ECSP992942A - HEMATOPOYETIC STIMULATION - Google Patents
HEMATOPOYETIC STIMULATIONInfo
- Publication number
- ECSP992942A ECSP992942A ECSP992942A ECSP992942A EC SP992942 A ECSP992942 A EC SP992942A EC SP992942 A ECSP992942 A EC SP992942A EC SP992942 A ECSP992942 A EC SP992942A
- Authority
- EC
- Ecuador
- Prior art keywords
- hematopoietic cells
- stimulation
- products
- methods
- hydroxyl group
- Prior art date
Links
- 230000000638 stimulation Effects 0.000 title abstract 2
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000004471 Glycine Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Se proporcionan métodos y productos para la estimulación de células hematopoyéticas, para la prevención de bajos niveles de células hematopoyéticas, y las producción de incrementos números de células hematopoyéticas y células sanguineas maduras. Los métodos y productos se pueden usar tanto in vitro. Los agentes útiles de acuerdo con la invención son compuestos de fórmula I: (gráfico), en donde m es un entero entre 0 y 10, inclusive; A y A1 son residuos Laminoácidos (para glicina no hay dicha distinción), de manera que el A en cada unidad de repetición entre paréntesis puede ser un residuo de aminoácido diferente; el C enlazado a B se encuentra en la configuración L; los enlaces entre A y N A1 y C y entre péptidos; y cada X1 y X2 es independientemente, un grupo hidroxilo o un grupo capaz de ser hidrolizado a un grupo hidroxilo en solución acuosa a pH fisiológico.Methods and products are provided for the stimulation of hematopoietic cells, for the prevention of low levels of hematopoietic cells, and the production of increased numbers of hematopoietic cells and mature blood cells. The methods and products can be used both in vitro. Agents useful in accordance with the invention are compounds of formula I: (graph), wherein m is an integer from 0 to 10, inclusive; A and A1 are Lamino Acid residues (for glycine there is no such distinction), so that A in each repeat unit in parentheses may be a different amino acid residue; C linked to B is in configuration L; the bonds between A and N A1 and C and between peptides; and each X1 and X2 is independently a hydroxyl group or a group capable of being hydrolyzed to a hydroxyl group in aqueous solution at physiological pH.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP992942 ECSP992942A (en) | 1999-05-04 | 1999-05-04 | HEMATOPOYETIC STIMULATION |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP992942 ECSP992942A (en) | 1999-05-04 | 1999-05-04 | HEMATOPOYETIC STIMULATION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP992942A true ECSP992942A (en) | 1999-07-08 |
Family
ID=42043932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP992942 ECSP992942A (en) | 1999-05-04 | 1999-05-04 | HEMATOPOYETIC STIMULATION |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP992942A (en) |
-
1999
- 1999-05-04 EC ECSP992942 patent/ECSP992942A/en unknown
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