ECSP993094A - NEW PHARMACEUTICAL USES FOR US INHIBITORS - Google Patents
NEW PHARMACEUTICAL USES FOR US INHIBITORSInfo
- Publication number
- ECSP993094A ECSP993094A ECSP993094A ECSP993094A EC SP993094 A ECSP993094 A EC SP993094A EC SP993094 A ECSP993094 A EC SP993094A EC SP993094 A ECSP993094 A EC SP993094A
- Authority
- EC
- Ecuador
- Prior art keywords
- combination
- inhibitors
- treatment
- nos
- alone
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 4
- 102000008299 Nitric Oxide Synthase Human genes 0.000 abstract 4
- 108010021487 Nitric Oxide Synthase Proteins 0.000 abstract 4
- 239000013543 active substance Substances 0.000 abstract 3
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
- XADCESSVHJOZHK-UHFFFAOYSA-N Meperidine Chemical compound C=1C=CC=CC=1C1(C(=O)OCC)CCN(C)CC1 XADCESSVHJOZHK-UHFFFAOYSA-N 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 208000008784 apnea Diseases 0.000 abstract 1
- 230000003930 cognitive ability Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940080861 demerol Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 206010022437 insomnia Diseases 0.000 abstract 1
- 229960005181 morphine Drugs 0.000 abstract 1
- 201000003631 narcolepsy Diseases 0.000 abstract 1
- 230000003533 narcotic effect Effects 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 229940127240 opiate Drugs 0.000 abstract 1
- 229940124641 pain reliever Drugs 0.000 abstract 1
- 208000019116 sleep disease Diseases 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención hace referencia a nuevos usos farmacéuticos para compuestos que presentan actividad como inhibidores de la óxido nítrico sintetasa (NOS). Más especificamente, hace referencia al uso de inhibidores NOS y, en particular, a los inhibidores neuronales NOS (N-NOS) selectivos: (a) solos o en combinación con otro agente activo para el tratamiento de la psoriasis; (b) en combinación con un agente antiinflamatorio para el tratamiento de trastornos inflamatorios; (c) en combinación con un analgésico narcótico (opiáceos como la morfina o el demerol, por ejemplo) para el tratamiento del dolor; (d) solo o en combinación con otros agentes activos para el desarrollo de la capacidad cognitiva; y (f) solo o en combinación con otros agentes activos para el tratamiento de trastornos del sueño, como apnea, narcolepsia o insomnio.The present invention relates to new pharmaceutical uses for compounds that exhibit activity as nitric oxide synthase (NOS) inhibitors. More specifically, it refers to the use of NOS inhibitors and, in particular, selective NOS neuronal inhibitors (N-NOS): (a) alone or in combination with another active agent for the treatment of psoriasis; (b) in combination with an anti-inflammatory agent for the treatment of inflammatory disorders; (c) in combination with a narcotic pain reliever (opiates such as morphine or demerol, for example) for the treatment of pain; (d) alone or in combination with other active agents for the development of cognitive ability; and (f) alone or in combination with other active agents for the treatment of sleep disorders, such as apnea, narcolepsy, or insomnia.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993094 ECSP993094A (en) | 1999-08-11 | 1999-08-11 | NEW PHARMACEUTICAL USES FOR US INHIBITORS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993094 ECSP993094A (en) | 1999-08-11 | 1999-08-11 | NEW PHARMACEUTICAL USES FOR US INHIBITORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP993094A true ECSP993094A (en) | 1999-10-06 |
Family
ID=42044081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP993094 ECSP993094A (en) | 1999-08-11 | 1999-08-11 | NEW PHARMACEUTICAL USES FOR US INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP993094A (en) |
-
1999
- 1999-08-11 EC ECSP993094 patent/ECSP993094A/en unknown
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