ECSP993125A - Derivados de piperidina - Google Patents
Derivados de piperidinaInfo
- Publication number
- ECSP993125A ECSP993125A ECSP993125A ECSP993125A EC SP993125 A ECSP993125 A EC SP993125A EC SP993125 A ECSP993125 A EC SP993125A EC SP993125 A ECSP993125 A EC SP993125A
- Authority
- EC
- Ecuador
- Prior art keywords
- lower alkyl
- disorders
- lower alkoxy
- cycloalkyl
- disease
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical class C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 206010012289 Dementia Diseases 0.000 abstract 2
- 208000002193 Pain Diseases 0.000 abstract 2
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000000044 Amnesia Diseases 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000027796 Blood pressure disease Diseases 0.000 abstract 1
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- 206010010904 Convulsion Diseases 0.000 abstract 1
- 208000026139 Memory disease Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000013200 Stress disease Diseases 0.000 abstract 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
- 201000004810 Vascular dementia Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 208000005298 acute pain Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000006984 memory degeneration Effects 0.000 abstract 1
- 208000023060 memory loss Diseases 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
El presente invento se refirere a compuestos de la fórmula general (gráfico), en donde R1 es tetrahidronaftilo; o -(CH2)nC6H5-R4 es H, alquilo inferior o alcoxilo inferior; o cicloalquilo de C5-C12, opcionalmente sustituido por alquilo inferior; R2 es H, OH, alcoxilo inferior, alqueniloxilo inferior o alquilo inferior; R3 es cicloalquilo de C5-C7 o fenilo, opcionalmente sustituido por OH, halógeno, alcoxilo inferior, alqueniloxilo inferior, alquilo inferior u -O-(CH2)n-C6H5 en donde n es 0-3; y a sus sales de adición de ácido farmacéuticamente aceptables. Los compuestos de la fórmula general I son apropiados para el tratamiento de deficits de memoria y atención, transtornos psiquiátricos, neurológicos y fisiológicos, tal como ansiedad y trastornos de estres, depresión, pérdida de memoria debido a enfermedad de Alzheimer u otras demencias tales como demencia vascular y complejo por demencia por SIDA, enfermedad de Parkinson, epilepsia y convulsiones, condiciones de dolor agudo y/ocrónico, sintomas de abstinencia de drogas adictas y reducción de su abuso/deseo, control de equilibrio de agua, excresión de Na+ y trastornos de presión arterial y trastornos metabólicos tal como obesidad.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993125 ECSP993125A (es) | 1999-09-07 | 1999-09-07 | Derivados de piperidina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993125 ECSP993125A (es) | 1999-09-07 | 1999-09-07 | Derivados de piperidina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP993125A true ECSP993125A (es) | 2000-05-08 |
Family
ID=42044113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP993125 ECSP993125A (es) | 1999-09-07 | 1999-09-07 | Derivados de piperidina |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP993125A (es) |
-
1999
- 1999-09-07 EC ECSP993125 patent/ECSP993125A/es unknown
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