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Priority to ECSP993127priorityCriticalpatent/ECSP993127A/en
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La invención se refiere a determinados compuestos antagonistas del receptor 5-HT4 representados por la fórmula (gráfico), en que Z está representado por la fórmula (A) o (B): (gráfcio), en que R1, R2, R3, R4 y R5 y los otros sustituyentes son como se define en la especificación; y los isómeros individuales, mezclas racémicas o no recámicas de isómeros y sales o hidratos de los mismos farmacéuticamente aceptables. La invención se refiere adicionalmente a composiciones farmacéuticas que contienen dichos compuestos y a su uso como agentes terapéuticos.The invention relates to certain 5-HT4 receptor antagonist compounds represented by the formula (graph), in which Z is represented by the formula (A) or (B): (graph), in which R1, R2, R3, R4 and R5 and the other substituents are as defined in the specification; and the individual isomers, racemic or non-ceramic mixtures of isomers and pharmaceutically acceptable salts or hydrates thereof. The invention further relates to pharmaceutical compositions containing such compounds and their use as therapeutic agents.
ECSP9931271999-09-091999-09-09
DERIVATIVES OF DIHYDROBENZODIOXIN CARBOXAMIDE AND KETONE
ECSP993127A
(en)
2-Furanecarboxylic acid hydrazide compounds, pharmaceutical compositions containing them and use thereof for the preparation of a preventive or therapeutic agent
NON-PEPTIDIC INHIBITING COMPOUNDS OF THE VLA-4 DEPENDENT CELL UNION IN THE TREATMENT OF INFLAMMATORY, AUTOIMMUNE AND RESPIRATORY DISEASES; PHARMACEUTICAL COMPOSITION AND TREATMENT PROCEDURE
COMPOUNDS DERIVED FROM 3H-QUINAZOLIN-4-ONA, ITS PREPARATION PROCESS, PHARMACEUTICAL COMPOSITION CONTAINING THEM, AND USE IN THE TREATMENT AND PREVENTION OF DISEASES MEDIATED BY MAO-B INHIBITORS, SUCH AS THE DISEASE OF ALZHEIMER AND DEMENCIER
ANTI-TUMOR AND ANTIVIRAL RENTAL AGENTS, PROCEDURE FOR THEIR PREPARATION, USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITION CONTAINING SUCH AGENTS.
DERIVATIVES OF BETA-ALANINA, USEFUL AS RECEIVER ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE USE OF THEM FOR THE PREPARATION OF MEDICINES
Use of benzopyran derivatives for the preparation of pharmaceutical compositions intended for the treatment of pathologies associated with the Na + -independent C1-HCO3 yields