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Priority to ECSP993127priorityCriticalpatent/ECSP993127A/en
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La invención se refiere a determinados compuestos antagonistas del receptor 5-HT4 representados por la fórmula (gráfico), en que Z está representado por la fórmula (A) o (B): (gráfcio), en que R1, R2, R3, R4 y R5 y los otros sustituyentes son como se define en la especificación; y los isómeros individuales, mezclas racémicas o no recámicas de isómeros y sales o hidratos de los mismos farmacéuticamente aceptables. La invención se refiere adicionalmente a composiciones farmacéuticas que contienen dichos compuestos y a su uso como agentes terapéuticos.The invention relates to certain 5-HT4 receptor antagonist compounds represented by the formula (graph), in which Z is represented by the formula (A) or (B): (graph), in which R1, R2, R3, R4 and R5 and the other substituents are as defined in the specification; and the individual isomers, racemic or non-ceramic mixtures of isomers and pharmaceutically acceptable salts or hydrates thereof. The invention further relates to pharmaceutical compositions containing such compounds and their use as therapeutic agents.
ECSP9931271999-09-091999-09-09
DERIVATIVES OF DIHYDROBENZODIOXIN CARBOXAMIDE AND KETONE
ECSP993127A
(en)
2-Furanecarboxylic acid hydrazide compounds, pharmaceutical compositions containing them and use thereof for the preparation of a preventive or therapeutic agent
NON-PEPTIDIC INHIBITING COMPOUNDS OF THE VLA-4 DEPENDENT CELL UNION IN THE TREATMENT OF INFLAMMATORY, AUTOIMMUNE AND RESPIRATORY DISEASES; PHARMACEUTICAL COMPOSITION AND TREATMENT PROCEDURE
COMPOUNDS DERIVED FROM 3H-QUINAZOLIN-4-ONA, ITS PREPARATION PROCESS, PHARMACEUTICAL COMPOSITION CONTAINING THEM, AND USE IN THE TREATMENT AND PREVENTION OF DISEASES MEDIATED BY MAO-B INHIBITORS, SUCH AS THE DISEASE OF ALZHEIMER AND DEMENCIER
ANTI-TUMOR AND ANTIVIRAL RENTAL AGENTS, PROCEDURE FOR THEIR PREPARATION, USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITION CONTAINING SUCH AGENTS.
Use of benzopyran derivatives for the preparation of pharmaceutical compositions intended for the treatment of pathologies associated with the Na + -independent C1-HCO3 yields
DERIVATIVES OF BETA-ALANINA, USEFUL AS RECEIVER ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE USE OF THEM FOR THE PREPARATION OF MEDICINES