ECSP993132A - HIV PROTEASE INHIBITORS - Google Patents

HIV PROTEASE INHIBITORS

Info

Publication number
ECSP993132A
ECSP993132A ECSP993132A ECSP993132A EC SP993132 A ECSP993132 A EC SP993132A EC SP993132 A ECSP993132 A EC SP993132A EC SP993132 A ECSP993132 A EC SP993132A
Authority
EC
Ecuador
Prior art keywords
protease inhibitors
hiv protease
dihydropyrones
relates
present
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Vara Prasad Venkata Nagendra Josyula
John Michael Domagala
Christopher Andrew Gajda
Bradley Dean Tait
Frederick Earl Boyer Jr
Edmund Lee Ellsworth
Susan Elizabeth Hagen
Michael James Lovdahl
Elizabeth Ann Lunney
Larry James Markoski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP993132 priority Critical patent/ECSP993132A/en
Publication of ECSP993132A publication Critical patent/ECSP993132A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se relaciona con dihidropironas novedosas con heterociclos unidos a ellas que tienen propiedades farmocológicas mejoradas que inhiben en forma potente la HIV aspartil proteasa bloqueando la infectividad del HIV. Las dihidroperonas son útiles en el desarrollo de terapias para el tratamiento de infecciones y enfermedades virales, incluyendo el SIDA. La presente invención se refiere también a los métodos de sintesis de las dihidropironas y los intermedios útiles en la preparación de los compuestos finales.The present invention relates to novel dihydropyrones with heterocycles attached to them that have improved pharmacological properties that potently inhibit HIV aspartyl protease by blocking HIV infectivity. Dihydroperones are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS. The present invention also relates to methods of synthesizing dihydropyrones and intermediates useful in the preparation of the final compounds.

ECSP993132 1999-09-10 1999-09-10 HIV PROTEASE INHIBITORS ECSP993132A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP993132 ECSP993132A (en) 1999-09-10 1999-09-10 HIV PROTEASE INHIBITORS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP993132 ECSP993132A (en) 1999-09-10 1999-09-10 HIV PROTEASE INHIBITORS

Publications (1)

Publication Number Publication Date
ECSP993132A true ECSP993132A (en) 2000-05-25

Family

ID=42044120

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP993132 ECSP993132A (en) 1999-09-10 1999-09-10 HIV PROTEASE INHIBITORS

Country Status (1)

Country Link
EC (1) ECSP993132A (en)

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