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La presente invención se refiere a composiciones farmacéuticas sólidas, de forma de dosificación oral, de liberación sostenida, que contienen cantidades terapéuticas de un agente farmacéuticamente activo, celulosa hidroxipropilmetílica, y un polímero hidrfilico no iónico seleccionado a partir del grupo que consiste en celulosa hidroxietílica que tiene un peso molecular promedio en número de 90000 a 1300000, celulosa hidroxipropilica que tiene un peso molecular promedio de 370000 a 1500000 y poli (óxido de etileno) que tiene un peso molecular promedio en número de 100000 a 500000.The present invention relates to solid, sustained release, oral dosage form pharmaceutical compositions containing therapeutic amounts of a pharmaceutically active agent, hydroxypropylmethyl cellulose, and a nonionic hydrophilic polymer selected from the group consisting of hydroxyethyl cellulose which It has a number average molecular weight of 90,000 to 1,300,000, hydroxypropyl cellulose that has an average molecular weight of 370,000 to 1,500,000, and poly (ethylene oxide) that has a number average molecular weight of 100,000 to 500,000.
ECSP9931751999-10-121999-10-12
PHARMACEUTICAL COMPOSITION OF SUSTAINED LIBERATION, AND METHOD TO RELEASE A PHARMACEUTICALLY ACTIVE AGENT
ECSP993175A
(en)
copolymer, process for preparing same, biodegradable particle, use thereof, process for preparing a release system, perfume composition, and fragrant product
PILLS THAT HAVE A PHARMACEUTICAL MATRIX THAT PROVIDE AN APPROPRIATE PROFILE OF DRUG RELEASE, COMPOSITION FOR THE PREPARATION OF SAID PILLS, PROCESS FOR PREPARING SUCH PILLS AND DOSAGE FORMS OF SUCH COMPOSITION.