ECSP993185A - DERIVATIVES OF TIAZOLE - Google Patents
DERIVATIVES OF TIAZOLEInfo
- Publication number
- ECSP993185A ECSP993185A ECSP993185A ECSP993185A EC SP993185 A ECSP993185 A EC SP993185A EC SP993185 A ECSP993185 A EC SP993185A EC SP993185 A ECSP993185 A EC SP993185A
- Authority
- EC
- Ecuador
- Prior art keywords
- cell
- arthritis
- well
- tiazole
- derivatives
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 206010003246 arthritis Diseases 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 206010012689 Diabetic retinopathy Diseases 0.000 abstract 1
- 206010016654 Fibrosis Diseases 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 208000010191 Osteitis Deformans Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 208000027868 Paget disease Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 230000008619 cell matrix interaction Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000004761 fibrosis Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000008611 intercellular interaction Effects 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 208000002780 macular degeneration Diseases 0.000 abstract 1
- 208000027202 mammary Paget disease Diseases 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 208000037803 restenosis Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000004614 tumor growth Effects 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compuestos de fórmula (I) (gráfico), asi como las sales y esteres farmacéuticamente aceptables de los mismos, en donde R1, R2 y R3 tienen el significado dado en la reivindicación 1, inhiben la unión de las proteínas adhesiva a la superficie de diferentes tipos de células y en consecuencia influyen sobre las interacciones célula-célula y célula-matriz. Pueden emplearse en forma de preparaciones farmacéuticas para el control o prevención de neoplasmas, metástasis de tumores, crecimiento tumoral, osteoporosis, enfermedad de Paget, retinopatía diabética, degeneración macular, restenosis depués de una intervención vascular, psoriasis, artritis, artritis, fibrosis, deficiencia renal, asi como infecciones causadas por virus, bacterias u hongos.Compounds of formula (I) (graph), as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2 and R3 have the meaning given in claim 1, inhibit the binding of adhesive proteins to the surface of different cell types and consequently influence cell-cell and cell-matrix interactions. They can be used in the form of pharmaceutical preparations for the control or prevention of neoplasms, tumor metastases, tumor growth, osteoporosis, Paget's disease, diabetic retinopathy, macular degeneration, restenosis after vascular intervention, psoriasis, arthritis, arthritis, fibrosis, deficiency. kidney, as well as infections caused by viruses, bacteria or fungi.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993185 ECSP993185A (en) | 1999-10-21 | 1999-10-21 | DERIVATIVES OF TIAZOLE |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993185 ECSP993185A (en) | 1999-10-21 | 1999-10-21 | DERIVATIVES OF TIAZOLE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP993185A true ECSP993185A (en) | 2000-05-25 |
Family
ID=42044174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP993185 ECSP993185A (en) | 1999-10-21 | 1999-10-21 | DERIVATIVES OF TIAZOLE |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP993185A (en) |
-
1999
- 1999-10-21 EC ECSP993185 patent/ECSP993185A/en unknown
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