ECSP993191A - COMPOUNDS DERIVED FROM AN AMINE CORE WHICH ARE INHIBITORS OF THE IMPDH ENZYME - Google Patents
COMPOUNDS DERIVED FROM AN AMINE CORE WHICH ARE INHIBITORS OF THE IMPDH ENZYMEInfo
- Publication number
- ECSP993191A ECSP993191A ECSP993191A ECSP993191A EC SP993191 A ECSP993191 A EC SP993191A EC SP993191 A ECSP993191 A EC SP993191A EC SP993191 A ECSP993191 A EC SP993191A
- Authority
- EC
- Ecuador
- Prior art keywords
- inhibitors
- compounds derived
- impdh
- amine core
- impdh enzyme
- Prior art date
Links
- 101710200424 Inosine-5'-monophosphate dehydrogenase Proteins 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 150000001412 amines Chemical group 0.000 title 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 101710088194 Dehydrogenase Proteins 0.000 abstract 1
- HAEJPQIATWHALX-KQYNXXCUSA-N ITP Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C(N=CNC2=O)=C2N=C1 HAEJPQIATWHALX-KQYNXXCUSA-N 0.000 abstract 1
- 206010052779 Transplant rejections Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención describe la identificación de nuevos inhibidores de IMPDH (inosina-5¿-monofosfato deshidorgenasa). Los compuestos y composiciones farmacéuticas descritos aquí son útiles para tratar o prevenir padecimientos asociados con IMPDH, tal como rechazo de transplante y enfermedades y enfermedades autoinmunes.The present invention describes the identification of new IMPDH inhibitors (inosine-5¿-monophosphate dehydrogenase). The compounds and pharmaceutical compositions described herein are useful for treating or preventing conditions associated with IMPDH, such as transplant rejection and autoimmune diseases and conditions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993191 ECSP993191A (en) | 1999-10-25 | 1999-10-25 | COMPOUNDS DERIVED FROM AN AMINE CORE WHICH ARE INHIBITORS OF THE IMPDH ENZYME |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993191 ECSP993191A (en) | 1999-10-25 | 1999-10-25 | COMPOUNDS DERIVED FROM AN AMINE CORE WHICH ARE INHIBITORS OF THE IMPDH ENZYME |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP993191A true ECSP993191A (en) | 1999-11-29 |
Family
ID=42044180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP993191 ECSP993191A (en) | 1999-10-25 | 1999-10-25 | COMPOUNDS DERIVED FROM AN AMINE CORE WHICH ARE INHIBITORS OF THE IMPDH ENZYME |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP993191A (en) |
-
1999
- 1999-10-25 EC ECSP993191 patent/ECSP993191A/en unknown
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