ECSP993222A - PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULES - Google Patents
PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULESInfo
- Publication number
- ECSP993222A ECSP993222A ECSP993222A ECSP993222A EC SP993222 A ECSP993222 A EC SP993222A EC SP993222 A ECSP993222 A EC SP993222A EC SP993222 A ECSP993222 A EC SP993222A
- Authority
- EC
- Ecuador
- Prior art keywords
- capsules
- active agent
- present
- manufacture
- dissolution rate
- Prior art date
Links
- 239000002775 capsule Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 239000007788 liquid Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 3
- 238000004090 dissolution Methods 0.000 abstract 2
- 239000000945 filler Substances 0.000 abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000005538 encapsulation Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a un procedimiento para el encapsulado de una masa de relleno sensible al cizallamiento en una cápsula, caracterizado porque dicha masa de relleno se calienta y seguidamente se enfria inmediatamente antes del encapsulado. La invención se refiere también a las cápsulas que pueden obtenerse mediante dicho procedimiento. El procedimiento de acuerdo con la presente invención npermite la obtención de cápsulas que presentan una alta y constante velocidad de disolución. La cantidad de agente activio ingerido puede por lo tanto disminuirse dado que el propio agente activo se disuelve rápidamente. Los costos totales del medicamento por lo tanto también disminuyen. La alta homogenidad (y por lo tanto la alta y constante velocidad de disolución) de las cápsulas elaboradas con el procedimiento de acuerdo con la presente invención garantiza una biodisponibilidad y efecto terapéutico reproducibles del agente activo que está contenido en la misma.The present invention relates to a process for encapsulating a shear-sensitive filler mass in a capsule, characterized in that said filler mass is heated and then cooled immediately prior to encapsulation. The invention also relates to the capsules that can be obtained by said procedure. The process according to the present invention does not allow the obtaining of capsules that have a high and constant dissolution rate. The amount of active agent ingested can therefore be decreased since the active agent itself dissolves rapidly. Total drug costs therefore also decrease. The high homogeneity (and therefore the high and constant dissolution rate) of the capsules made with the process according to the present invention guarantees a reproducible bioavailability and therapeutic effect of the active agent contained therein.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993222 ECSP993222A (en) | 1999-11-17 | 1999-11-17 | PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULES |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP993222 ECSP993222A (en) | 1999-11-17 | 1999-11-17 | PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP993222A true ECSP993222A (en) | 2000-06-19 |
Family
ID=42044210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP993222 ECSP993222A (en) | 1999-11-17 | 1999-11-17 | PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULES |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP993222A (en) |
-
1999
- 1999-11-17 EC ECSP993222 patent/ECSP993222A/en unknown
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