EE03067B1 - 2,6-diisopropüülfenooli puhastamise meetod - Google Patents
2,6-diisopropüülfenooli puhastamise meetodInfo
- Publication number
- EE03067B1 EE03067B1 EE9400247A EE9400247A EE03067B1 EE 03067 B1 EE03067 B1 EE 03067B1 EE 9400247 A EE9400247 A EE 9400247A EE 9400247 A EE9400247 A EE 9400247A EE 03067 B1 EE03067 B1 EE 03067B1
- Authority
- EE
- Estonia
- Prior art keywords
- purification
- phenol
- propofol
- temperature
- diisopropylphenol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/68—Purification; separation; Use of additives, e.g. for stabilisation
- C07C37/70—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment
- C07C37/84—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment by crystallisation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Artificial Filaments (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI912102A FI912102A7 (fi) | 1991-04-30 | 1991-04-30 | Menetelmä 2,6-di-isopropyylifenolin puhdistamiseksi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE03067B1 true EE03067B1 (et) | 1998-02-16 |
Family
ID=8532425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EE9400247A EE03067B1 (et) | 1991-04-30 | 1994-11-16 | 2,6-diisopropüülfenooli puhastamise meetod |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5175376A (et) |
| EP (1) | EP0511947B1 (et) |
| AT (1) | ATE140212T1 (et) |
| DE (2) | DE511947T1 (et) |
| EE (1) | EE03067B1 (et) |
| ES (1) | ES2091449T3 (et) |
| FI (1) | FI912102A7 (et) |
| SG (1) | SG44681A1 (et) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1269977B (it) * | 1994-07-01 | 1997-04-16 | Archimica Spa | Purificazione del propofol |
| IT1270093B (it) * | 1994-09-28 | 1997-04-28 | Zambon Spa | Processo per la purificazione di 2,6-diisopropilfenolo |
| US5705039A (en) * | 1995-10-13 | 1998-01-06 | Albemarle Corporation | Process for purifying a 2,6-dialkylphenol |
| US5591311A (en) * | 1995-10-26 | 1997-01-07 | Albemarle Corporation | Process for purifying a 2,6-dialkylphenol |
| WO2000014043A1 (en) † | 1998-09-03 | 2000-03-16 | General Electric Company | Purification of alkylated phenols by melt crystallization |
| WO2000034218A1 (en) * | 1998-12-04 | 2000-06-15 | Dong Kook Pharmaceutical Co., Ltd. | Process for purification of 2,6-diisopropyl phenol |
| US7862552B2 (en) | 2005-05-09 | 2011-01-04 | Boston Scientific Scimed, Inc. | Medical devices for treating urological and uterine conditions |
| CN101081804B (zh) * | 2007-06-04 | 2010-08-25 | 西安力邦制药有限公司 | 一种双异丙酚的精制方法 |
| WO2011161687A1 (en) | 2010-06-23 | 2011-12-29 | Harman Finochem Limited | Process for preparing extra pure 2, 6-diisopropyl phenol |
| EP2522651B1 (en) | 2011-05-12 | 2013-11-20 | Siegfried AG | Process for the purification of 2,6-diisopropyl phenol |
| CN105777497A (zh) * | 2014-12-26 | 2016-07-20 | 辽宁药联制药有限公司 | 一种丙泊酚精馏前馏分的处理方法 |
| CN114133318B (zh) * | 2021-12-09 | 2023-08-29 | 广东嘉博制药有限公司 | 一种降除丙泊酚产品中丙泊酚杂质o的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2536040A (en) * | 1948-03-02 | 1951-01-02 | Shell Dev | Purification of alkyl phenols |
| US2831898A (en) * | 1954-04-29 | 1958-04-22 | Ethyl Corp | Phenol alkylation process |
| DE1145628B (de) * | 1961-06-28 | 1963-03-21 | Ruetgerswerke Ag | Verfahren zur Gewinnung von reinem 4-Methyl-2, 6-di-tertiaer-butylphenol |
| BE716974A (et) * | 1967-06-27 | 1968-12-02 | ||
| US4433181A (en) * | 1980-06-12 | 1984-02-21 | Koppers Company, Inc. | Process for recovering a crystallization medium |
| US4391998A (en) * | 1981-10-21 | 1983-07-05 | Mobil Oil Corporation | Production of para-isopropylphenol |
| JPS6212733A (ja) * | 1985-07-10 | 1987-01-21 | Honsyu Kagaku Kogyo Kk | フェノ−ル類のo−イソプロピル化方法 |
-
1991
- 1991-04-30 FI FI912102A patent/FI912102A7/fi not_active Application Discontinuation
-
1992
- 1992-04-27 EP EP92850096A patent/EP0511947B1/en not_active Expired - Lifetime
- 1992-04-27 SG SG1996005476A patent/SG44681A1/en unknown
- 1992-04-27 AT AT92850096T patent/ATE140212T1/de not_active IP Right Cessation
- 1992-04-27 DE DE199292850096T patent/DE511947T1/de active Pending
- 1992-04-27 DE DE69212065T patent/DE69212065T2/de not_active Expired - Fee Related
- 1992-04-27 ES ES92850096T patent/ES2091449T3/es not_active Expired - Lifetime
- 1992-04-30 US US07/876,873 patent/US5175376A/en not_active Expired - Lifetime
-
1994
- 1994-11-16 EE EE9400247A patent/EE03067B1/et not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SG44681A1 (en) | 1997-12-19 |
| FI912102L (fi) | 1992-10-31 |
| ES2091449T3 (es) | 1996-11-01 |
| DE69212065D1 (de) | 1996-08-14 |
| DE511947T1 (de) | 1993-04-08 |
| FI912102A7 (fi) | 1992-10-31 |
| ATE140212T1 (de) | 1996-07-15 |
| DE69212065T2 (de) | 1997-01-30 |
| US5175376A (en) | 1992-12-29 |
| EP0511947B1 (en) | 1996-07-10 |
| EP0511947A1 (en) | 1992-11-04 |
| FI912102A0 (fi) | 1991-04-30 |
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Legal Events
| Date | Code | Title | Description |
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| KB4A | Valid patent at the end of a year |
Effective date: 20021231 |
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| KB4A | Valid patent at the end of a year |
Effective date: 20031231 |
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| KB4A | Valid patent at the end of a year |
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| KB4A | Valid patent at the end of a year |
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| KB4A | Valid patent at the end of a year |
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| KB4A | Valid patent at the end of a year |
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| KB4A | Valid patent at the end of a year |
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| KB4A | Valid patent at the end of a year |
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| KB4A | Valid patent at the end of a year |
Effective date: 20101231 |
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| MM4A | Lapsed by not paying the annual fees |
Effective date: 20111116 |