EE03669B1 - Liquid alendronate preparations and method of preparation - Google Patents

Liquid alendronate preparations and method of preparation

Info

Publication number: EE03669B1
Authority: EE; Estonia
Prior art keywords: preparations; preparation; alendronate; liquid; liquid alendronate
Prior art date: 1996-10-04

Application number

EEP199900113A

Other languages

Estonian (et)

Other versions

EE9900113A (en

Inventor

J. Nerurkar Maneesh

A. Hunke William

Ostovic Drazen

Original Assignee

Merck & Co., Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-04

Filing date

1997-10-02

Publication date

2002-04-15

1997-01-13 Priority claimed from GBGB9700541.7A external-priority patent/GB9700541D0/en

1997-10-02 Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.

1999-10-15 Publication of EE9900113A publication Critical patent/EE9900113A/en

2002-04-15 Publication of EE03669B1 publication Critical patent/EE03669B1/en

Links

238000002360 preparation method Methods 0.000 title 2
OGSPWJRAVKPPFI-UHFFFAOYSA-N Alendronic Acid Chemical compound NCCCC(O)(P(O)(O)=O)P(O)(O)=O OGSPWJRAVKPPFI-UHFFFAOYSA-N 0.000 title 1
229940062527 alendronate Drugs 0.000 title 1
239000007788 liquid Substances 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Physical Education & Sports Medicine (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EEP199900113A 1996-10-04 1997-10-02 Liquid alendronate preparations and method of preparation EE03669B1 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US2676596P	1996-10-04	1996-10-04
GBGB9700541.7A GB9700541D0 (en)	1997-01-13	1997-01-13	Liquid alendronate formulation
US3600297P	1997-01-22	1997-01-22
PCT/US1997/015740 WO1998014196A1 (en)	1996-10-04	1997-10-02	Liquid alendronate formulations

Publications (2)

Publication Number	Publication Date
EE9900113A EE9900113A (en)	1999-10-15
EE03669B1 true EE03669B1 (en)	2002-04-15

Family

ID=27268667

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP199900113A EE03669B1 (en)	1996-10-04	1997-10-02	Liquid alendronate preparations and method of preparation

Country Status (20)

Country	Link
EP (1)	EP1007054A4 (en)
JP (1)	JP2001501222A (en)
CN (1)	CN1238691A (en)
AU (1)	AU723357B2 (en)
BG (1)	BG103306A (en)
BR (1)	BR9712197A (en)
CA (1)	CA2267370A1 (en)
CZ (1)	CZ116999A3 (en)
EA (1)	EA001213B1 (en)
EE (1)	EE03669B1 (en)
HU (1)	HUP0000125A3 (en)
IL (1)	IL129127A0 (en)
IS (1)	IS5012A (en)
NO (1)	NO991569L (en)
NZ (1)	NZ334836A (en)
PL (1)	PL332496A1 (en)
SK (1)	SK42999A3 (en)
TR (1)	TR199900730T2 (en)
WO (1)	WO1998014196A1 (en)
YU (1)	YU17499A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7560490B2 (en) *	2001-01-23	2009-07-14	Gador S.A.	Composition comprising bisphosphonates for prevention and/or treatment of metabolic diseases of bones, process for preparing such composition and use thereof
US7645460B2 (en)	2004-05-24	2010-01-12	The Procter & Gamble Company	Dosage forms of risedronate
US7645459B2 (en)	2004-05-24	2010-01-12	The Procter & Gamble Company	Dosage forms of bisphosphonates
US20080286359A1 (en)	2004-05-24	2008-11-20	Richard John Dansereau	Low Dosage Forms Of Risedronate Or Its Salts
US20080287400A1 (en)	2004-05-24	2008-11-20	Richard John Dansereau	Low Dosage Forms Of Risedronate Or Its Salts
US7473684B2 (en)	2005-09-16	2009-01-06	Selamine Limited	Bisphosphonate formulation
CA2622322A1 (en) *	2005-09-16	2007-03-22	Selamine Ltd	Bisphosphonate formulation
JP2010043119A (en) *	2009-10-16	2010-02-25	Gador Sa	Composition for preventing and/or treating bone metabolic disease, method of preparing the same and use thereof
US8568747B1 (en)	2012-10-05	2013-10-29	Silvergate Pharmaceuticals, Inc.	Enalapril compositions
US9463183B1 (en)	2015-10-30	2016-10-11	Silvergate Pharmaceuticals, Inc.	Lisinopril formulations
US9669008B1 (en)	2016-03-18	2017-06-06	Silvergate Pharmaceuticals, Inc.	Enalapril formulations

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4206209A (en) *	1978-11-02	1980-06-03	Kracauer Paul	Sublingual aspirin tablet
IT1201087B (en) *	1982-04-15	1989-01-27	Gentili Ist Spa	PHARMACOLOGICALLY ACTIVE BIPPHOSPHONES, PROCEDURE FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
US4922007A (en) *	1989-06-09	1990-05-01	Merck & Co., Inc.	Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
US5019651A (en) *	1990-06-20	1991-05-28	Merck & Co., Inc.	Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof
US5270365A (en) *	1991-12-17	1993-12-14	Merck & Co., Inc.	Prevention and treatment of periodontal disease with alendronate
US5358941A (en) *	1992-12-02	1994-10-25	Merck & Co., Inc.	Dry mix formulation for bisphosphonic acids with lactose
FR2703590B1 (en) *	1993-04-05	1995-06-30	Sanofi Elf	USE OF BISPHOSPHONIC ACID DERIVATIVES FOR THE PREPARATION OF MEDICINES FOR PROMOTING BONE REPAIR.
US5510517A (en) *	1993-08-25	1996-04-23	Merck & Co., Inc.	Process for producing N-amino-1-hydroxy-alkylidene-1,1-bisphosphonic acids
US5462932A (en) *	1994-05-17	1995-10-31	Merck & Co., Inc.	Oral liquid alendronate formulations
US5780455A (en) *	1994-08-24	1998-07-14	Merck & Co., Inc.	Intravenous alendronate formulations
US5616571A (en) *	1995-06-06	1997-04-01	Merck & Co., Inc.	Bisphosphonates prevent bone loss associated with immunosuppressive therapy

1997
- 1997-10-02 CN CN97180165A patent/CN1238691A/en active Pending
- 1997-10-02 EP EP97945195A patent/EP1007054A4/en not_active Withdrawn
- 1997-10-02 JP JP10516541A patent/JP2001501222A/en active Pending
- 1997-10-02 CA CA002267370A patent/CA2267370A1/en not_active Abandoned
- 1997-10-02 WO PCT/US1997/015740 patent/WO1998014196A1/en not_active Ceased
- 1997-10-02 HU HU0000125A patent/HUP0000125A3/en unknown
- 1997-10-02 EE EEP199900113A patent/EE03669B1/en not_active IP Right Cessation
- 1997-10-02 NZ NZ334836A patent/NZ334836A/en unknown
- 1997-10-02 CZ CZ991169A patent/CZ116999A3/en unknown
- 1997-10-02 SK SK429-99A patent/SK42999A3/en unknown
- 1997-10-02 TR TR1999/00730T patent/TR199900730T2/en unknown
- 1997-10-02 BR BR9712197-5A patent/BR9712197A/en unknown
- 1997-10-02 AU AU46448/97A patent/AU723357B2/en not_active Ceased
- 1997-10-02 PL PL97332496A patent/PL332496A1/en unknown
- 1997-10-02 IL IL12912797A patent/IL129127A0/en unknown
- 1997-10-02 EA EA199900352A patent/EA001213B1/en not_active IP Right Cessation
1999
- 1999-03-26 IS IS5012A patent/IS5012A/en unknown
- 1999-03-30 NO NO991569A patent/NO991569L/en not_active Application Discontinuation
- 1999-03-31 YU YU17499A patent/YU17499A/en unknown
- 1999-04-02 BG BG103306A patent/BG103306A/en unknown

Also Published As

Publication number	Publication date
IL129127A0 (en)	2000-02-17
JP2001501222A (en)	2001-01-30
EA199900352A1 (en)	1999-08-26
CN1238691A (en)	1999-12-15
NO991569L (en)	1999-06-04
CA2267370A1 (en)	1998-04-09
EE9900113A (en)	1999-10-15
PL332496A1 (en)	1999-09-13
NO991569D0 (en)	1999-03-30
BR9712197A (en)	1999-08-31
HUP0000125A3 (en)	2001-04-28
NZ334836A (en)	2000-11-24
YU17499A (en)	1999-11-22
EP1007054A4 (en)	2000-07-19
AU723357B2 (en)	2000-08-24
TR199900730T2 (en)	1999-07-21
AU4644897A (en)	1998-04-24
EP1007054A1 (en)	2000-06-14
IS5012A (en)	1999-03-26
HUP0000125A2 (en)	2000-06-28
EA001213B1 (en)	2000-12-25
CZ116999A3 (en)	1999-09-15
BG103306A (en)	2000-01-31
WO1998014196A1 (en)	1998-04-09
SK42999A3 (en)	2000-01-18

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2004-06-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20031002

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