EE04878B1 - šhendid maop?hja kahjustunud relaksatsiooni raviks, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod - Google Patents

šhendid maop?hja kahjustunud relaksatsiooni raviks, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod

Info

Publication number
EE04878B1
EE04878B1 EEP200200694A EEP200200694A EE04878B1 EE 04878 B1 EE04878 B1 EE 04878B1 EE P200200694 A EEP200200694 A EE P200200694A EE P200200694 A EEP200200694 A EE P200200694A EE 04878 B1 EE04878 B1 EE 04878B1
Authority
EE
Estonia
Prior art keywords
preparation
compounds
treatment
pharmaceutical composition
gastrointestinal lesions
Prior art date
Application number
EEP200200694A
Other languages
English (en)
Estonian (et)
Inventor
Van Emelen Kristof
Frans Leopold De Bruyn Marcel
Jesus Alc βzar-Vaca Manuel
Ignacio Andr�s-Gil Jos�
Javier Fern βndez-Gadea Francisco
Encarnacion Matesanz-Ballesteros Maria
Manuel Bartolom�-Nebreda Jos�
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of EE200200694A publication Critical patent/EE200200694A/xx
Publication of EE04878B1 publication Critical patent/EE04878B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EEP200200694A 2000-06-22 2001-06-13 šhendid maop?hja kahjustunud relaksatsiooni raviks, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod EE04878B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00202180 2000-06-22
PCT/EP2001/006749 WO2001098306A1 (en) 2000-06-22 2001-06-13 Compounds for treating impaired fundic relaxation

Publications (2)

Publication Number Publication Date
EE200200694A EE200200694A (et) 2004-06-15
EE04878B1 true EE04878B1 (et) 2007-08-15

Family

ID=8171674

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200694A EE04878B1 (et) 2000-06-22 2001-06-13 šhendid maop?hja kahjustunud relaksatsiooni raviks, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod

Country Status (33)

Country Link
US (2) US7081453B2 (cs)
EP (1) EP1296987B1 (cs)
JP (1) JP4911860B2 (cs)
KR (1) KR100821107B1 (cs)
CN (2) CN1288157C (cs)
AR (1) AR032158A1 (cs)
AT (1) ATE312104T1 (cs)
AU (1) AU783292B2 (cs)
BG (1) BG65895B1 (cs)
BR (1) BR0111859B1 (cs)
CA (1) CA2410233C (cs)
CZ (1) CZ305005B6 (cs)
DE (1) DE60115647T2 (cs)
EA (1) EA005760B1 (cs)
EE (1) EE04878B1 (cs)
EG (1) EG24462A (cs)
ES (1) ES2254467T3 (cs)
HR (1) HRP20020988B1 (cs)
HU (1) HU227398B1 (cs)
IL (2) IL153559A0 (cs)
IS (1) IS2618B (cs)
JO (1) JO2352B1 (cs)
MX (1) MXPA02012844A (cs)
MY (1) MY155267A (cs)
NO (1) NO328547B1 (cs)
NZ (1) NZ522519A (cs)
PA (1) PA8519601A1 (cs)
PL (1) PL201656B1 (cs)
SA (1) SA01220442B1 (cs)
SK (1) SK287730B6 (cs)
UA (1) UA74576C2 (cs)
WO (1) WO2001098306A1 (cs)
ZA (1) ZA200210303B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE04780B1 (et) * 1999-06-02 2007-02-15 Janssen Pharmaceutica N.V. Aminoalküül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod
SK286159B6 (sk) 1999-06-02 2008-04-07 Janssen Pharmaceutica N. V. Benzodioxánový, benzofuránový alebo benzopyránovýderivát, spôsob jeho prípravy, tento derivát na použitie ako liečivo, farmaceutická kompozícia obsahujúca tento derivát a spôsob jej prípravy
JO2352B1 (en) * 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) * 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
EP1622569B1 (en) 2003-04-24 2015-12-02 Incyte Corporation Aza spiro alkane derivatives as inhibitors of metallproteases
JP4896476B2 (ja) * 2005-09-16 2012-03-14 広栄化学工業株式会社 メチルオキシメチルアミノピリジン誘導体及びその製造方法
US7999107B2 (en) 2007-01-31 2011-08-16 Merck Sharp & Dohme Corp. Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators
JP2010526825A (ja) * 2007-05-10 2010-08-05 エーエムアール テクノロジー インコーポレイテッド アリール置換およびヘテロアリール置換テトラヒドロベンゾ−１，４−ジアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
CN103917529B (zh) 2011-11-11 2016-08-17 辉瑞大药厂 2-硫代嘧啶酮类
AU2016257179A1 (en) 2015-05-05 2017-11-02 Pfizer Inc. 2-thiopyrimidinones
CN105481839B (zh) * 2015-11-23 2018-05-11 安徽千和新材料科技发展有限公司 一种光活性环氧啉对映体的制备方法
EP3229193A1 (en) 2016-04-07 2017-10-11 The Boeing Company A computer-implemented method and system for sharing information between passengers and air traffic management stakeholders

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
DE2400049A1 (de) * 1974-01-02 1975-07-10 Spumalit Anstalt Transportkasten aus kunststoff, insbesondere fuer flaschen
GR71865B (cs) * 1978-03-20 1983-07-07 Ciba Geigy
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
DE3484096D1 (de) * 1983-11-30 1991-03-14 Janssen Pharmaceutica Nv Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine.
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
ZA931343B (en) 1992-03-06 1993-09-24 Akzo Nv 1,4-dioxino(2,3-b)pyridine derivatives.
US6403103B1 (en) * 1994-08-12 2002-06-11 Bio Merieux Trypanosoma cruzi antigen, gene encoding therefore, and methods of detecting and treating chagas disease
FR2744451B1 (fr) * 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
EE04780B1 (et) * 1999-06-02 2007-02-15 Janssen Pharmaceutica N.V. Aminoalküül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod
SK286159B6 (sk) 1999-06-02 2008-04-07 Janssen Pharmaceutica N. V. Benzodioxánový, benzofuránový alebo benzopyránovýderivát, spôsob jeho prípravy, tento derivát na použitie ako liečivo, farmaceutická kompozícia obsahujúca tento derivát a spôsob jej prípravy
TWI225488B (en) * 1999-12-21 2004-12-21 Janssen Pharmaceutica Nv Derivatives of homopiperidinyl substituted benzimidazole analogues
JO2352B1 (en) * 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus

Also Published As

Publication number Publication date
WO2001098306A1 (en) 2001-12-27
HU227398B1 (hu) 2011-05-30
BR0111859A (pt) 2003-05-13
ZA200210303B (en) 2004-03-19
DE60115647T2 (de) 2006-08-24
MXPA02012844A (es) 2003-05-15
JP4911860B2 (ja) 2012-04-04
EE200200694A (et) 2004-06-15
BR0111859B1 (pt) 2015-01-06
US20060142318A1 (en) 2006-06-29
AU8386401A (en) 2002-01-02
AU783292B2 (en) 2005-10-13
BG65895B1 (bg) 2010-04-30
UA74576C2 (en) 2006-01-16
CN100516066C (zh) 2009-07-22
HUP0301185A3 (en) 2009-03-30
NO20026219D0 (no) 2002-12-23
BG107313A (bg) 2003-06-30
US20040019051A1 (en) 2004-01-29
IL153559A0 (en) 2003-07-06
PL358886A1 (en) 2004-08-23
AR032158A1 (es) 2003-10-29
SA01220442B1 (ar) 2008-05-21
HRP20020988A2 (en) 2005-02-28
PA8519601A1 (es) 2002-08-26
NO328547B1 (no) 2010-03-15
MY155267A (en) 2015-09-30
EA200300049A1 (ru) 2003-04-24
SK287730B6 (en) 2011-07-06
KR100821107B1 (ko) 2008-04-14
CN1437602A (zh) 2003-08-20
EA005760B1 (ru) 2005-06-30
HK1057896A1 (en) 2004-04-23
CZ2003115A3 (cs) 2003-06-18
ATE312104T1 (de) 2005-12-15
EP1296987B1 (en) 2005-12-07
JO2352B1 (en) 2006-12-12
KR20030007566A (ko) 2003-01-23
IS2618B (is) 2010-04-15
HUP0301185A2 (hu) 2003-08-28
IL153559A (en) 2008-03-20
JP2004501157A (ja) 2004-01-15
US7081453B2 (en) 2006-07-25
SK492003A3 (en) 2003-07-01
NO20026219L (no) 2003-02-17
US7423048B2 (en) 2008-09-09
CA2410233A1 (en) 2001-12-27
ES2254467T3 (es) 2006-06-16
CN1288157C (zh) 2006-12-06
CZ305005B6 (cs) 2015-03-25
EG24462A (en) 2009-07-16
IS6591A (is) 2002-10-25
HRP20020988B1 (en) 2011-06-30
NZ522519A (en) 2003-09-26
CN1781921A (zh) 2006-06-07
CA2410233C (en) 2011-01-25
PL201656B1 (pl) 2009-04-30
EP1296987A1 (en) 2003-04-02
DE60115647D1 (de) 2006-01-12

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20190613