EE04953B1 - Tsinkhaluronaadi kasutamine ja meetod ravimkoostise valmistamiseks - Google Patents

Tsinkhaluronaadi kasutamine ja meetod ravimkoostise valmistamiseks

Info

Publication number: EE04953B1
Authority: EE; Estonia
Prior art keywords: aluronate; zinc; preparation; pharmaceutical composition; peptic ulcer
Prior art date: 1997-04-29

Application number

EEP199900470A

Other languages

English (en)

Estonian (et)

Inventor

βszl� Szporny L (surnud)

βnos Ill�s J

Matuz Judit

Neszm�lyi Erzs�bet

βborn� Forrai G

Zs�ka Erika

Stefk� B�la

S βghy Katalin

Original Assignee

Richter Gedeon Vegy�szeti Gy βr Rt.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-29

Filing date

1998-04-28

Publication date

2008-02-15

1998-04-28 Application filed by Richter Gedeon Vegy�szeti Gy βr Rt. filed Critical Richter Gedeon Vegy�szeti Gy βr Rt.

2000-06-15 Publication of EE9900470A publication Critical patent/EE9900470A/xx

2008-02-15 Publication of EE04953B1 publication Critical patent/EE04953B1/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 title 1
239000011701 zinc Substances 0.000 title 1
229910052725 zinc Inorganic materials 0.000 title 1
208000008469 Peptic Ulcer Diseases 0.000 abstract 2
208000011906 peptic ulcer disease Diseases 0.000 abstract 2
239000004480 active ingredient Substances 0.000 abstract 1
VJVOFLWZDWLHNR-MRCUWXFGSA-N icosan-9-yl (z)-docos-13-enoate Chemical compound CCCCCCCCCCCC(CCCCCCCC)OC(=O)CCCCCCCCCCC\C=C/CCCCCCCC VJVOFLWZDWLHNR-MRCUWXFGSA-N 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Dermatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EEP199900470A 1997-04-29 1998-04-28 Tsinkhaluronaadi kasutamine ja meetod ravimkoostise valmistamiseks EE04953B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU9700826A HU225991B1 (en)	1997-04-29	1997-04-29	Use of the zinc hyaluronate associate (complex) for the preparation of pharmaceutical compositions for oral use against peptic ulcer
PCT/HU1998/000044 WO1998048815A1 (en)	1997-04-29	1998-04-28	Use of zinc hyaluronate against peptic ulcer

Publications (2)

Publication Number	Publication Date
EE9900470A EE9900470A (et)	2000-06-15
EE04953B1 true EE04953B1 (et)	2008-02-15

Family

ID=89995068

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP199900470A EE04953B1 (et)	1997-04-29	1998-04-28	Tsinkhaluronaadi kasutamine ja meetod ravimkoostise valmistamiseks

Country Status (26)

Country	Link
US (1)	US6656921B1 (da)
EP (1)	EP1017403B1 (da)
JP (1)	JP2001522361A (da)
KR (1)	KR100572190B1 (da)
CN (1)	CN1126548C (da)
AT (1)	ATE320814T1 (da)
BG (1)	BG64458B1 (da)
BR (1)	BR9809354A (da)
CA (1)	CA2286756C (da)
CZ (1)	CZ297317B6 (da)
DE (1)	DE69833937T2 (da)
DK (1)	DK1017403T3 (da)
EA (1)	EA002134B1 (da)
EE (1)	EE04953B1 (da)
ES (1)	ES2259813T3 (da)
HU (1)	HU225991B1 (da)
IL (1)	IL132214A0 (da)
NO (1)	NO328313B1 (da)
NZ (1)	NZ500978A (da)
PL (1)	PL189526B1 (da)
PT (1)	PT1017403E (da)
SK (1)	SK284864B6 (da)
TW (1)	TW501927B (da)
UA (1)	UA62964C2 (da)
WO (1)	WO1998048815A1 (da)
ZA (1)	ZA983626B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU225991B1 (en)	1997-04-29	2008-02-28	Richter Gedeon Nyrt	Use of the zinc hyaluronate associate (complex) for the preparation of pharmaceutical compositions for oral use against peptic ulcer
ITPD980168A1 (it) *	1998-07-06	2000-01-06	Fidia Advanced Biopolymers Srl	Composizioni biocompatibili e biodegradabili comprendenti acido ialuronico e suoi derivati per il trattamento delle ulcere dell'appara
HUP0303779A2 (en) *	2003-11-20	2006-02-28	Richter Gedeon Vegyeszet	Pharmaceutical compositions containing hyaluronan complex for the treatment of sclerosis multiplex
US8057294B2 (en) *	2005-09-09	2011-11-15	Wms Gaming Inc.	Wagering game system with community gaming system
CN100355790C (zh) *	2005-11-04	2007-12-19	山东福瑞达生物化工有限公司	一种透明质酸锌的制备方法
CN100348621C (zh) *	2005-12-02	2007-11-14	凌沛学	透明质酸铋及其制备方法和应用
CN1329414C (zh) *	2005-12-02	2007-08-01	凌沛学	透明质酸铋钾及其制备方法和应用
CN101023961B (zh) *	2006-02-23	2010-07-21	山东省生物药物研究院	一种含透明质酸钠和锌盐的药物组合物
ITMI20061132A1 (it) *	2006-06-13	2007-12-14	Sinclair Pharmaceuticals Ltd	Composizioni topiche antimicrobiche comprendenti lattoferrina, acido ialuronico o suoi sali ed estratti vegetali
TWI383796B (zh) *	2009-08-14	2013-02-01	Holy Stone Healthcare Co Ltd	Use of hyaluronic acid mixture for the treatment and prevention of peptic ulcer and duodenal ulcer
TWI516269B (zh) *	2009-08-14	2016-01-11	禾伸堂生技股份有限公司	使用於炎症性腸疾病（ｉｂｄ）治療和預防之透明質酸混合物
HUP0900717A3 (en) *	2009-11-18	2012-02-28	Richter Gedeon Nyrt	Pharmaceutical composition for urological use containing zinc hyaluronate
US8722644B2 (en)	2010-01-04	2014-05-13	Holy Stone Healthcare Co., Ltd.	Mixture of hyaluronic acid for treating and preventing peptic ulcer and duodenal ulcer
US20110166099A1 (en) *	2010-01-04	2011-07-07	Wu Tsung-Chung	Mixture of hyaluronic acid for treating and preventing peptic ulcer and duodenal ulcer
ES2388281B1 (es) *	2010-12-27	2013-10-01	Laboratorios Viñas S.A.	Composición farmacéutica que comprende ácido hialurónico y un compuesto de zinc y pastilla con palito y procedimiento para preparación correspondientes
JP6095014B2 (ja) *	2012-03-01	2017-03-15	キユーピー株式会社	浮腫抑制用経口剤
JPWO2015076294A1 (ja) *	2013-11-22	2017-03-16	キユーピー株式会社	薬剤の副作用である胃潰瘍の発症抑制方法、および胃潰瘍発症が抑制された経口薬剤組成物ならびにその製造方法
CN104262499A (zh) *	2014-09-03	2015-01-07	佐源集团有限公司	一种低聚果糖锌及含有低聚果糖锌的口服液
CN108051553A (zh) *	2017-12-29	2018-05-18	武汉轻工大学	一种仔猪肠道功能保护剂的筛选方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1229075B (it) *	1985-04-05	1991-07-17	Fidia Farmaceutici	Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico
WO1987005517A1 (en) *	1986-03-14	1987-09-24	Bio-Technology General Corp.	Heavy metal salts of hyaluronic acid useful as antimicrobial agents
US6458774B1 (en) *	1989-02-24	2002-10-01	Richter Gedeon Vegyeszeti Gyar Rt.	Compositions containing hyaluronic acid associates and a process for preparing same
US5472950A (en)	1989-02-24	1995-12-05	Richter Gedeon Vegyeszeti Gyar Rt.	Compositions containing cobalt hyaluronic acid complex
HU203372B (en)	1989-02-24	1991-07-29	Richter Gedeon Vegyeszet	Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient
JPH0648950A (ja)	1992-07-30	1994-02-22	Taito Kk	抗潰瘍剤
HU225991B1 (en)	1997-04-29	2008-02-28	Richter Gedeon Nyrt	Use of the zinc hyaluronate associate (complex) for the preparation of pharmaceutical compositions for oral use against peptic ulcer
HU225329B1 (en) *	1996-09-12	2006-09-28	Richter Gedeon Vegyeszet	Use of zinc or cobalt hyaluronate associate for the manufacture of pharmaceutical compositions of antimicrobial activity

1997
- 1997-04-29 HU HU9700826A patent/HU225991B1/hu unknown
1998
- 1998-04-28 CN CN98804672A patent/CN1126548C/zh not_active Expired - Fee Related
- 1998-04-28 BR BR9809354-1A patent/BR9809354A/pt not_active IP Right Cessation
- 1998-04-28 CZ CZ0382799A patent/CZ297317B6/cs not_active IP Right Cessation
- 1998-04-28 IL IL13221498A patent/IL132214A0/xx not_active IP Right Cessation
- 1998-04-28 EP EP98920684A patent/EP1017403B1/en not_active Expired - Lifetime
- 1998-04-28 PT PT98920684T patent/PT1017403E/pt unknown
- 1998-04-28 UA UA99116468A patent/UA62964C2/uk unknown
- 1998-04-28 DK DK98920684T patent/DK1017403T3/da active
- 1998-04-28 PL PL98336482A patent/PL189526B1/pl unknown
- 1998-04-28 NZ NZ500978A patent/NZ500978A/en not_active IP Right Cessation
- 1998-04-28 WO PCT/HU1998/000044 patent/WO1998048815A1/en not_active Ceased
- 1998-04-28 ES ES98920684T patent/ES2259813T3/es not_active Expired - Lifetime
- 1998-04-28 EA EA199900983A patent/EA002134B1/ru not_active IP Right Cessation
- 1998-04-28 CA CA002286756A patent/CA2286756C/en not_active Expired - Fee Related
- 1998-04-28 SK SK1468-99A patent/SK284864B6/sk not_active IP Right Cessation
- 1998-04-28 JP JP54638898A patent/JP2001522361A/ja active Pending
- 1998-04-28 DE DE69833937T patent/DE69833937T2/de not_active Expired - Lifetime
- 1998-04-28 TW TW087106525A patent/TW501927B/zh not_active IP Right Cessation
- 1998-04-28 US US09/403,714 patent/US6656921B1/en not_active Expired - Lifetime
- 1998-04-28 KR KR1019997010037A patent/KR100572190B1/ko not_active Expired - Fee Related
- 1998-04-28 AT AT98920684T patent/ATE320814T1/de active
- 1998-04-28 EE EEP199900470A patent/EE04953B1/xx unknown
- 1998-04-29 ZA ZA983626A patent/ZA983626B/xx unknown
1999
- 1999-10-19 BG BG103822A patent/BG64458B1/bg unknown
- 1999-10-26 NO NO19995229A patent/NO328313B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO1998048815A1 (en)	1998-11-05
CZ297317B6 (cs)	2006-11-15
NO328313B1 (no)	2010-01-25
JP2001522361A (ja)	2001-11-13
IL132214A0 (en)	2001-03-19
EP1017403A1 (en)	2000-07-12
SK146899A3 (en)	2000-06-12
NO995229D0 (no)	1999-10-26
CN1254285A (zh)	2000-05-24
SK284864B6 (sk)	2006-01-05
US6656921B1 (en)	2003-12-02
EA199900983A1 (ru)	2000-08-28
DE69833937T2 (de)	2007-06-06
HU225991B1 (en)	2008-02-28
BG103822A (en)	2000-04-28
KR20010020413A (ko)	2001-03-15
BR9809354A (pt)	2000-07-04
CN1126548C (zh)	2003-11-05
UA62964C2 (en)	2004-01-15
ATE320814T1 (de)	2006-04-15
DK1017403T3 (da)	2006-07-31
HK1025250A1 (en)	2000-11-10
PL336482A1 (en)	2000-06-19
CZ382799A3 (cs)	2000-03-15
EE9900470A (et)	2000-06-15
CA2286756A1 (en)	1998-11-05
ES2259813T3 (es)	2006-10-16
NO995229L (no)	1999-12-22
HU9700826D0 (en)	1997-06-30
PT1017403E (pt)	2006-07-31
EA002134B1 (ru)	2001-12-24
BG64458B1 (bg)	2005-03-31
EP1017403B1 (en)	2006-03-22
DE69833937D1 (de)	2006-05-11
ZA983626B (en)	1998-11-05
HUP9700826A1 (hu)	1998-12-28
TW501927B (en)	2002-09-11
KR100572190B1 (ko)	2006-04-18
NZ500978A (en)	2001-05-25
CA2286756C (en)	2008-02-19
PL189526B1 (pl)	2005-08-31

Legal Events

Date	Code	Title	Description
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231

Publication	Publication Date	Title
EE9900470A (et)	2000-06-15	Tsinkhüaluronaadi kasutamine peptilise haavandi vastu
MY130477A (en)	2007-06-29	Pharmaceutical compositions for the treatmen of mucositis, stomatitis and behcet,s syndrome
UA56989C2 (uk)	2003-06-16	ФІЗІОЛОГІЧНО АКТИВНИЙ ПЕГ-КОН'ЮГАТ <font face="Symbol">a</font>-ІНТЕРФЕРОНУ, СПОСІБ ЙОГО ОДЕРЖАННЯ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ НА ЙОГО ОСНОВІ ТА СПОСІБ ЛІКУВАННЯ АБО ПРОФІЛАКТИКИ ІМУНОМОДУЛЯТОРНИХ ЗАХВОРЮВАНЬ
AU3435497A (en)	1998-01-14	Autocross-linked hyaluronic acid and related pharmaceutical compositions for the treatment of arthropathies
NO971889L (no)	1997-06-23	Forbindelser og sammensetninger for levering av aktive midler
TR199801315T2 (xx)	1998-10-21	X sendromunun tedavisi i�in bir ppar-alpha ve ppar-gamma antagonistinin kullan�lmas�.
DE69909818D1 (de)	2003-08-28	Pyrazolopyimidinon-derivate zur behandlung von impotenz
ATE254922T1 (de)	2003-12-15	Pharmazeutische zusammensetzungen mit antimikrobieller wirkung
BG103947A (en)	2000-07-31	Derivatives of 9-oxymerythromycin
CA2070685A1 (en)	1991-06-20	Method for treating painful, inflammatory or allergic disorders
UA37263C2 (uk)	2001-05-15	Протруйник та спосіб протруювання насіння
EA199700032A1 (ru)	1997-12-30	Дезинфицирующий состав "велтолен"
PL316656A1 (en)	1997-02-03	Free halophantrin base for use in treating marsh-fever and compositions containing same
CA2275167A1 (en)	1998-06-25	The topical use of kappa opioid agonists to treat ocular pain
AU8020698A (en)	1998-12-11	Use of glucosamine and glucosamine derivatives for quick alleviation of itching or localized pain
CA2529441A1 (en)	2005-01-06	Use of hyaluronic acid for preparing compositions for treating oral cavity aphthas
BG105275A (en)	2001-11-30	Tan-1057 derivatives
ATE201882T1 (de)	2001-06-15	Formulierung von energie
GB9505082D0 (en)	1995-05-03	Medicament
EP0244937A3 (en)	1988-07-20	Pharmaceutical compositions containing (R,S) or (S) N-(2-[2-hydroxy-3-phenoxypropyl]aminoethyl)isobutyramide
ATE193206T1 (de)	2000-06-15	Zusammensetzung zur behandlung oder vorbeugung von herpes
AU9080398A (en)	1999-03-29	Novel diamine alkylene diacetic or triacetic acid derivatives, preparation method, use in cosmetic and pharmaceutical compositions and compositions containing them
LV11593A (lv)	1996-12-20	Dimetikona pielietojums aizcietejumu arstesana
CA2269031A1 (en)	1998-04-23	Treatment of urinary incontinence and compositions for use therein
UA15363A (uk)	1997-06-30	Засіб для лікуваhhя відкритих пошкоджеhь

EE04953B1 - Tsinkhaluronaadi kasutamine ja meetod ravimkoostise valmistamiseks - Google Patents