EE200000592A - Method of Sterilization of Native Collagen in Liquid Medium, Sterile Native Collagen Obtained, Compositions Containing It and Their Use - Google Patents

Method of Sterilization of Native Collagen in Liquid Medium, Sterile Native Collagen Obtained, Compositions Containing It and Their Use

Info

Publication number
EE200000592A
EE200000592A EEP200000592A EEP200000592A EE200000592A EE 200000592 A EE200000592 A EE 200000592A EE P200000592 A EEP200000592 A EE P200000592A EE P200000592 A EEP200000592 A EE P200000592A EE 200000592 A EE200000592 A EE 200000592A
Authority
EE
Estonia
Prior art keywords
native collagen
collagen
liquid medium
sterile
sterilization
Prior art date
Application number
EEP200000592A
Other languages
Estonian (et)
Inventor
Mansour Hamza
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma Ag filed Critical Octapharma Ag
Publication of EE200000592A publication Critical patent/EE200000592A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/044—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Cardiology (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention concerns a method for preparing native collagen, comprising pretreatment of the collagen in a mixer with double transverse cutters equipped with a system controlling agitating and shearing velocity and a thermostat, and a subsequent step of sterilising the collagen in liquid medium. The invention also concerns a sterile collagen, in particular a collagen mostly of type I, in native state and in particular pharmaceutical and/or parapharmaceutical and /or medico-surgical and/or ophthalmologic an/or cosmetic compositions and applications thereof.
EEP200000592A 1998-04-10 1999-04-09 Method of Sterilization of Native Collagen in Liquid Medium, Sterile Native Collagen Obtained, Compositions Containing It and Their Use EE200000592A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9804531A FR2777284B1 (en) 1998-04-10 1998-04-10 PROCESS FOR THE STERILIZATION OF A NATIVE COLLAGEN IN A LIQUID MEDIUM, A STERILE NATIVE COLLAGEN OBTAINED, COMPOSITIONS CONTAINING THE SAME AND APPLICATIONS
PCT/FR1999/000814 WO1999052946A1 (en) 1998-04-10 1999-04-09 Method for sterilising native collagen in liquid medium, resulting native collagen, compositions containing same and uses

Publications (1)

Publication Number Publication Date
EE200000592A true EE200000592A (en) 2002-04-15

Family

ID=9525129

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000592A EE200000592A (en) 1998-04-10 1999-04-09 Method of Sterilization of Native Collagen in Liquid Medium, Sterile Native Collagen Obtained, Compositions Containing It and Their Use

Country Status (20)

Country Link
EP (1) EP1068240B1 (en)
JP (1) JP2002511489A (en)
KR (1) KR20010042539A (en)
CN (1) CN1304416A (en)
AT (1) ATE229982T1 (en)
AU (1) AU3151499A (en)
BR (1) BR9909566A (en)
CA (1) CA2327882A1 (en)
DE (1) DE69904578T2 (en)
EE (1) EE200000592A (en)
FR (1) FR2777284B1 (en)
HU (1) HUP0102575A2 (en)
ID (1) ID26038A (en)
IL (1) IL138562A0 (en)
NO (1) NO20005079L (en)
PL (1) PL343523A1 (en)
RU (1) RU2188206C2 (en)
WO (1) WO1999052946A1 (en)
YU (1) YU61100A (en)
ZA (1) ZA200005497B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE42190E1 (en) 1998-11-20 2011-03-01 Arena Pharmaceuticals, Inc. Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors
US20030017528A1 (en) 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
US7816492B2 (en) 1998-11-20 2010-10-19 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors
AT411326B (en) * 2000-06-20 2003-12-29 Biering Wolfgang HEMOSTATIC COLLAGEN PELLETS
RU2220724C1 (en) * 2002-11-20 2004-01-10 Государственное образовательное учреждение высшего профессионального образования Московская медицинская академия им. И.М. Сеченова Antibacterial and wound-healing agent "ultrakol"
CA2554994C (en) * 2004-01-30 2015-05-19 Ferrosan A/S Haemostatic sprays and compositions
JP4705359B2 (en) * 2004-10-20 2011-06-22 新田ゼラチン株式会社 Cosmetic composition comprising avian collagen
DE102005017845A1 (en) 2005-04-18 2006-10-19 Lohmann & Rauscher Gmbh & Co. Kg Autosterile, antiseptic collagen preparations, their use and methods of preparation
CN101332316B (en) * 2008-07-22 2012-12-26 广东冠昊生物科技股份有限公司 Biotype nose bridge implantation body
US20080102095A1 (en) * 2006-10-31 2008-05-01 Kent Young Acidic processes to prepare antimicrobial contact lenses
JP5632162B2 (en) * 2007-06-01 2014-11-26 協和発酵バイオ株式会社 Oral composition
RU2433828C1 (en) * 2010-10-14 2011-11-20 Закрытое акционерное общество "БИОМИР сервис" Injection heterogenic biopolymer hydrogel for substitutional and regenerative surgery and method of its obtaining
TWI552774B (en) * 2011-05-24 2016-10-11 武田公司 Rolled collagen carrier
JP6242874B2 (en) 2012-05-24 2017-12-06 タケダ エイエスＴａｋｅｄａ ＡＳ package
BR112014028594B1 (en) 2012-05-24 2021-11-30 Takeda As APPARATUS FOR PROVIDING A ROLLED COLLAGEN LOADER AND PROCESS TO ROLLS A COLLAGEN LOADER
CN102846536B (en) * 2012-09-26 2014-03-26 关节动力安达（天津）生物科技有限公司 Essence containing I type collagen
RU2597085C2 (en) * 2013-11-07 2016-09-10 Федеральное государственное бюджетное учреждение науки Институт биологии моря им. А.В. Жирмунского Дальневосточного отделения Российской академии наук (ИБМ ДВО РАН) Implanted matrix material for regenerative medicine and method of its production (versions)
WO2019208831A1 (en) * 2018-04-27 2019-10-31 凸版印刷株式会社 Extracellular-matrix-containing composition, temporary scaffold for three-dimensional tissue formation, three-dimensional tissue formation agent, and method for recovering cells from three-dimensional tissue
RU2715715C1 (en) * 2019-03-06 2020-03-03 Общество с ограниченной ответственностью фирмы "Имтек" Sterile transparent concentrated solution of biocompatible collagen, method for production and use thereof
CN110354246A (en) * 2019-07-22 2019-10-22 中肽生物科技(大连)有限公司 A kind of preparation method of the eye-candy liquid of nanoscale small molecule complex peptides

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
DE2462222A1 (en) * 1974-02-02 1976-05-06 Trommsdorff Fa H Soluble human collagen free of non-helical peptides - prepd by treating purified collagen with ficin or pepsin, used to accelerate wound or burn healing etc.
US3949073A (en) * 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
DE3522626A1 (en) * 1985-06-25 1987-01-08 Merz & Co Gmbh & Co SOLUBLE COLLAGEN SPONGE
FR2586703B1 (en) * 1985-09-02 1989-12-01 Merieux Inst PROCESS FOR EXTRACTING PLACENTAL COLLAGENS, COLLAGENS OBTAINED IN PARTICULAR IN THE FORM OF GELS OR SOLUTIONS AND THEIR APPLICATIONS
IT1181737B (en) * 1985-11-26 1987-09-30 Pierfrancesco Morganti Spongy matrix of natural animal collagen
GB8812992D0 (en) * 1988-06-01 1988-07-06 Natural Resources Mfg Ltd Improvements in/relating to protein products
RU2076718C1 (en) * 1993-04-09 1997-04-10 Курский Государственный Медицинский Институт Method of collagen preparing
FR2715309B1 (en) * 1994-01-24 1996-08-02 Imedex Adhesive composition, for surgical use, based on collagen modified by oxidative cutting and not crosslinked.
CA2146090C (en) * 1994-05-10 1998-11-24 Mark E. Mitchell Apparatus and method of mixing materials in a sterile environment
RU2116801C1 (en) * 1995-06-15 1998-08-10 Институт элементоорганических соединений РАН Method of the porous collagen-containing material preparing
US5670369A (en) * 1996-06-25 1997-09-23 Ranpak Corporation Method for the production of soluble collagen

Also Published As

Publication number Publication date
AU3151499A (en) 1999-11-01
ATE229982T1 (en) 2003-01-15
CN1304416A (en) 2001-07-18
YU61100A (en) 2003-10-31
PL343523A1 (en) 2001-08-27
ID26038A (en) 2000-11-16
EP1068240A1 (en) 2001-01-17
CA2327882A1 (en) 1999-10-21
NO20005079L (en) 2000-12-08
KR20010042539A (en) 2001-05-25
WO1999052946A1 (en) 1999-10-21
ZA200005497B (en) 2001-04-24
BR9909566A (en) 2000-12-26
EP1068240B1 (en) 2002-12-18
DE69904578T2 (en) 2003-11-20
FR2777284B1 (en) 2000-05-26
HUP0102575A2 (en) 2001-11-28
DE69904578D1 (en) 2003-01-30
JP2002511489A (en) 2002-04-16
NO20005079D0 (en) 2000-10-09
IL138562A0 (en) 2001-10-31
RU2188206C2 (en) 2002-08-27
FR2777284A1 (en) 1999-10-15

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