EE200100070A - (R)-(+)-N-[[3-[1-bensoüül-3-(3,4-diklorofenüül)piperidiin-3-üül] prop-1-üül]-4-fenüülpiperidiin-4-üül]-N-metüülatseetamiidi (osanetandi) kristallivormid ja nende valmistamise meetod - Google Patents

(R)-(+)-N-[[3-[1-bensoüül-3-(3,4-diklorofenüül)piperidiin-3-üül] prop-1-üül]-4-fenüülpiperidiin-4-üül]-N-metüülatseetamiidi (osanetandi) kristallivormid ja nende valmistamise meetod

Info

Publication number: EE200100070A
Authority: EE; Estonia
Prior art keywords: osetane; phenylpiperidin; methylacetamide; dichlorophenyl; piperidin
Prior art date: 1998-08-05

Application number

EEP200100070A

Other languages

English (en)

Inventor

Alcade Alain

Anne-Archard Gilles

Grosclaude Patrick

Monnier Olivier

Roche J�rome

Original Assignee

Sanofi-Synthlabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-05

Filing date

1999-08-03

Publication date

2002-06-17

1999-08-03 Application filed by Sanofi-Synthlabo filed Critical Sanofi-Synthlabo

2002-06-17 Publication of EE200100070A publication Critical patent/EE200100070A/et

2004-04-15 Publication of EE04274B1 publication Critical patent/EE04274B1/et

Links

125000004189 3,4-dichlorophenyl group Chemical group [H]C1=C([H])C(Cl)=C(Cl)C([H])=C1* 0.000 title 1
OHLUUHNLEMFGTQ-UHFFFAOYSA-N N-methylacetamide Chemical compound CNC(C)=O OHLUUHNLEMFGTQ-UHFFFAOYSA-N 0.000 title 1
125000004483 piperidin-3-yl group Chemical group N1CC(CCC1)* 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EEP200100070A 1998-08-05 1999-08-03 (R)-(+)-N-[[3-[1-bensoüül-3-(3,4-diklorofenüül)piperidiin-3-üül] prop-1-üül]-4-fenüülpiperidiin-4-üül]-N-metüülatseetamiidi (osanetandi) kristallivormid ja nende valmistamise meetod EE04274B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9810107A FR2782082B3 (fr)	1998-08-05	1998-08-05	Formes cristallines de (r)-(+)-n-[[3-[1-benzoyl-3-(3,4- dichlorophenyl)piperidin-3-yl]prop-1-yl]-4-phenylpiperidin-4 -yl]-n-methylacetamide (osanetant) et procede pour la preparation dudit compose
PCT/FR1999/001914 WO2000007987A1 (fr)	1998-08-05	1999-08-03	Formes cristallines du osanetant

Publications (2)

Publication Number	Publication Date
EE200100070A true EE200100070A (et)	2002-06-17
EE04274B1 EE04274B1 (et)	2004-04-15

Family

ID=9529458

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200100070A EE04274B1 (et)	1998-08-05	1999-08-03	(R)-(+)-N-[[3-[1-bensoüül-3-(3,4-diklorofenüül)piperidiin-3-üül] prop-1-üül]-4-fenüülpiperidiin-4-üül]-N-metüülatseetamiidi (osanetandi) kristallivormid ja nende valmistamise meetod

Country Status (31)

Country	Link
US (1)	US7041679B2 (et)
EP (1)	EP1102747B1 (et)
JP (1)	JP3807938B2 (et)
KR (1)	KR100571944B1 (et)
CN (1)	CN1114592C (et)
AR (1)	AR019953A1 (et)
AT (1)	ATE243197T1 (et)
AU (1)	AU748177B2 (et)
BR (1)	BR9913357A (et)
CA (1)	CA2339007A1 (et)
CO (1)	CO5070576A1 (et)
DE (1)	DE69908951T2 (et)
DK (1)	DK1102747T3 (et)
DZ (1)	DZ3074A1 (et)
EA (1)	EA003205B1 (et)
EE (1)	EE04274B1 (et)
ES (1)	ES2200535T3 (et)
FR (1)	FR2782082B3 (et)
HU (1)	HUP0103134A3 (et)
IS (1)	IS5821A (et)
MY (1)	MY121447A (et)
NO (1)	NO320645B1 (et)
NZ (1)	NZ509561A (et)
PL (1)	PL345999A1 (et)
PT (1)	PT1102747E (et)
SK (1)	SK1742001A3 (et)
TR (1)	TR200100261T2 (et)
TW (1)	TW527354B (et)
UA (1)	UA72890C2 (et)
WO (1)	WO2000007987A1 (et)
YU (1)	YU8601A (et)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE0100902D0 (sv) *	2001-03-15	2001-03-15	Astrazeneca Ab	Compounds
SE0202539D0 (sv)	2002-08-27	2002-08-27	Astrazeneca Ab	Compounds
US7648992B2 (en) *	2004-07-05	2010-01-19	Astrazeneca Ab	Hydantoin derivatives for the treatment of obstructive airway diseases
SE0401762D0 (sv) *	2004-07-05	2004-07-05	Astrazeneca Ab	Novel compounds
SE0403086D0 (sv) *	2004-12-17	2004-12-17	Astrazeneca Ab	Compounds
SE0403085D0 (sv) *	2004-12-17	2004-12-17	Astrazeneca Ab	Novel componds
TW200800954A (en) *	2006-03-16	2008-01-01	Astrazeneca Ab	Novel crystal modifications
TW200831488A (en) *	2006-11-29	2008-08-01	Astrazeneca Ab	Novel compounds
US20240336565A1 (en) *	2021-07-02	2024-10-10	Acer Therapeutics, Inc.	Solid forms of osanetant

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2719311B1 (fr)	1994-03-18	1998-06-26	Sanofi Sa	Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
JPH1053576A (ja) *	1996-06-07	1998-02-24	Eisai Co Ltd	塩酸ドネペジルの多形結晶およびその製造法
WO1998005640A2 (en) *	1996-08-05	1998-02-12	Smithkline Beecham S.P.A.	Process for the preparation of 3,3-disubstituted piperidines
US6040316A (en) *	1996-09-16	2000-03-21	Warner-Lambert Company	3-alkyl-3-phenyl-piperidines
FR2757543B1 (fr) *	1996-12-23	1999-04-02	Sanofi Sa	Procede pour la cristallisation d'un derive de tetrahydropyridine et formes cristallines ainsi obtenues

1998
- 1998-08-05 FR FR9810107A patent/FR2782082B3/fr not_active Expired - Lifetime
1999
- 1999-07-25 DZ DZ990156A patent/DZ3074A1/xx active
- 1999-07-28 AR ARP990103741A patent/AR019953A1/es unknown
- 1999-08-03 EA EA200100096A patent/EA003205B1/ru not_active IP Right Cessation
- 1999-08-03 TR TR2001/00261T patent/TR200100261T2/xx unknown
- 1999-08-03 AT AT99936672T patent/ATE243197T1/de not_active IP Right Cessation
- 1999-08-03 BR BR9913357-1A patent/BR9913357A/pt not_active IP Right Cessation
- 1999-08-03 PT PT99936672T patent/PT1102747E/pt unknown
- 1999-08-03 ES ES99936672T patent/ES2200535T3/es not_active Expired - Lifetime
- 1999-08-03 WO PCT/FR1999/001914 patent/WO2000007987A1/fr not_active Ceased
- 1999-08-03 DK DK99936672T patent/DK1102747T3/da active
- 1999-08-03 HU HU0103134A patent/HUP0103134A3/hu unknown
- 1999-08-03 SK SK174-2001A patent/SK1742001A3/sk unknown
- 1999-08-03 PL PL99345999A patent/PL345999A1/xx not_active Application Discontinuation
- 1999-08-03 YU YU8601A patent/YU8601A/sh unknown
- 1999-08-03 NZ NZ509561A patent/NZ509561A/xx unknown
- 1999-08-03 EP EP99936672A patent/EP1102747B1/fr not_active Expired - Lifetime
- 1999-08-03 CN CN99810182A patent/CN1114592C/zh not_active Expired - Fee Related
- 1999-08-03 KR KR1020017001460A patent/KR100571944B1/ko not_active Expired - Fee Related
- 1999-08-03 MY MYPI99003297A patent/MY121447A/en unknown
- 1999-08-03 CA CA002339007A patent/CA2339007A1/en not_active Abandoned
- 1999-08-03 JP JP2000563621A patent/JP3807938B2/ja not_active Expired - Fee Related
- 1999-08-03 UA UA2001010591A patent/UA72890C2/xx unknown
- 1999-08-03 DE DE69908951T patent/DE69908951T2/de not_active Expired - Fee Related
- 1999-08-03 EE EEP200100070A patent/EE04274B1/et not_active IP Right Cessation
- 1999-08-03 AU AU51685/99A patent/AU748177B2/en not_active Ceased
- 1999-08-04 TW TW088113235A patent/TW527354B/zh not_active IP Right Cessation
- 1999-08-04 CO CO99049286A patent/CO5070576A1/es unknown
2001
- 2001-01-23 IS IS5821A patent/IS5821A/is unknown
- 2001-02-01 NO NO20010553A patent/NO320645B1/no unknown
2003
- 2003-08-28 US US10/651,313 patent/US7041679B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69908951T2 (de)	2004-05-19
CA2339007A1 (en)	2000-02-17
HUP0103134A2 (en)	2002-06-29
TR200100261T2 (tr)	2001-06-21
HK1035535A1 (en)	2001-11-30
UA72890C2 (en)	2005-05-16
JP2002522419A (ja)	2002-07-23
PT1102747E (pt)	2003-09-30
NO20010553D0 (no)	2001-02-01
DK1102747T3 (da)	2003-09-29
CN1314888A (zh)	2001-09-26
DE69908951D1 (de)	2003-07-24
BR9913357A (pt)	2001-05-15
JP3807938B2 (ja)	2006-08-09
PL345999A1 (en)	2002-01-14
EA200100096A1 (ru)	2001-08-27
IS5821A (is)	2001-01-23
HUP0103134A3 (en)	2003-03-28
US20040044215A1 (en)	2004-03-04
NZ509561A (en)	2002-10-25
WO2000007987A1 (fr)	2000-02-17
EP1102747B1 (fr)	2003-06-18
ES2200535T3 (es)	2004-03-01
EE04274B1 (et)	2004-04-15
NO20010553L (no)	2001-04-05
NO320645B1 (no)	2006-01-09
MY121447A (en)	2006-01-28
AU5168599A (en)	2000-02-28
US7041679B2 (en)	2006-05-09
TW527354B (en)	2003-04-11
FR2782082A1 (fr)	2000-02-11
FR2782082B3 (fr)	2000-09-22
CN1114592C (zh)	2003-07-16
AU748177B2 (en)	2002-05-30
KR20010072220A (ko)	2001-07-31
DZ3074A1 (fr)	2004-07-20
KR100571944B1 (ko)	2006-04-18
YU8601A (sh)	2003-07-07
AR019953A1 (es)	2002-03-27
ATE243197T1 (de)	2003-07-15
SK1742001A3 (en)	2001-11-06
EP1102747A1 (fr)	2001-05-30
CO5070576A1 (es)	2001-08-28
EA003205B1 (ru)	2003-02-27

Legal Events

Date	Code	Title	Description
2005-02-15	HC1A	Change of owner name
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2008-04-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20070803

Publication	Publication Date	Title
FI972037L (fi)	1997-07-11	Parannettu menetelmä syötävien pakkausten valmistamiseksi ja koostumuksia niitä varten
DE69612185D1 (de)	2001-04-26	Bleichverfahren und bleichmittelzusammensetzung
DE59903302D1 (de)	2002-12-12	Verfahren und spinnmaschine zum herstellen von coregarn
NO953658D0 (no)	1995-09-15	Fremgangsmåte for fremstilling av 3-[4-(2-aminoetoksy)-benzoylÅ-2-aryl-6-hydroksybenzo[bÅtiofener
DE69536084D1 (de)	2010-08-05	Halbleiterbauelement und Verfahren zu seiner Herstellung
DE69830500D1 (de)	2005-07-14	Verfahren und zusammensetzungen zum bleichen von zähnen
BR9408540A (pt)	1997-05-20	Ferramenta de inserçao e método de produçao de uma ferramenta de inserçao
DE69615361D1 (de)	2001-10-25	Melkverfahren und melkmaschine
DE69911730D1 (de)	2003-11-06	Zahnbleichmittelsystem und Verfahren
DE69621777D1 (de)	2002-07-18	Formen von paroxetin hydrochlorid
NO20005202L (no)	2001-01-04	Fremgangsmåte for fremstilling av börstevarer og börstevarer fremstilt ifölge fremgangsmåten
DE69938533D1 (de)	2008-05-29	Trägheitssensor und Verfahren zu seiner Herstellung
EE200100070A (et)	2002-06-17	(R)-(+)-N-[[3-[1-bensoüül-3-(3,4-diklorofenüül)piperidiin-3-üül] prop-1-üül]-4-fenüülpiperidiin-4-üül]-N-metüülatseetamiidi (osanetandi) kristallivormid ja nende valmistamise meetod
DE69419922D1 (de)	1999-09-09	Verfahren zum kontinuierlichen Conchieren von Schokolade
ID20624A (id)	1999-01-28	Proses pembuatan 2'-flouro-5-metil-betha-l-rabinofuranosiluridin
DE69617035D1 (de)	2001-12-20	Waschmittelzusammensetzungen und verfahren zu ihrer herstellung
BR9915444B1 (pt)	2013-10-22	"processo para encapsular uma massa de enchimento"
DE19604279B4 (de)	2005-04-28	Einsatzwerkzeuge für Bohrhämmer und Verfahren zu seiner Herstellung
PL342064A1 (en)	2001-05-21	Method of obtaining (-)-cis-3-hydroxy-methyl-4-(2,4,6-trimethoxyphenyl)piperidine
DE69926978D1 (de)	2005-10-06	Flüssigkeitsgefüllter Schwingungsisolator und ein Verfahren zu seiner Herstellung
DE69914820D1 (de)	2004-03-25	Verbindungshalbleiter-Kristall und Verfahren zu seiner Herstellung
BR9402627A (pt)	1995-06-06	Processo de destalar manocas e máquina destaladeira
FI972055A0 (fi)	1997-05-14	Syljen analysointimenetelmä
FI972310L (fi)	1997-07-21	Substituoituja 2-(fosfinyylioksimetyyli-1,2,5-tiadiatsolidin-3-oni-1,1-dioksideja, niitä sisältäviä koostumuksia ja menetelmä niiden käyttämiseksi
ID26708A (id)	2001-02-01	Proses pembuatan kaprolaktam