EE200200314A - Tsüklilised kvaternaarsed ammooniumiühendid - Google Patents

Tsüklilised kvaternaarsed ammooniumiühendid

Info

Publication number
EE200200314A
EE200200314A EEP200200314A EEP200200314A EE200200314A EE 200200314 A EE200200314 A EE 200200314A EE P200200314 A EEP200200314 A EE P200200314A EE P200200314 A EEP200200314 A EE P200200314A EE 200200314 A EE200200314 A EE 200200314A
Authority
EE
Estonia
Prior art keywords
quaternary ammonium
ammonium compounds
cyclic quaternary
cyclic
compounds
Prior art date
Application number
EEP200200314A
Other languages
English (en)
Inventor
Siu Leung Choi Lewis
N. Beatch Gregory
P. Page Clive
Original Assignee
Ucb Farchim S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Farchim S.A. filed Critical Ucb Farchim S.A.
Publication of EE200200314A publication Critical patent/EE200200314A/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
EEP200200314A 1999-12-15 2000-12-15 Tsüklilised kvaternaarsed ammooniumiühendid EE200200314A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2292351 1999-12-15
PCT/CA2000/001506 WO2001044192A1 (en) 1999-12-15 2000-12-15 Cyclic quaternary ammonium compounds

Publications (1)

Publication Number Publication Date
EE200200314A true EE200200314A (et) 2003-08-15

Family

ID=4164887

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200314A EE200200314A (et) 1999-12-15 2000-12-15 Tsüklilised kvaternaarsed ammooniumiühendid

Country Status (19)

Country Link
US (1) US20030166629A1 (et)
EP (1) EP1278731A1 (et)
JP (1) JP2003516966A (et)
KR (1) KR20020074170A (et)
CN (1) CN1425005A (et)
AU (1) AU2334501A (et)
BG (1) BG106816A (et)
BR (1) BR0016431A (et)
CZ (1) CZ20022095A3 (et)
EE (1) EE200200314A (et)
HU (1) HUP0301686A2 (et)
IL (1) IL150179A0 (et)
IS (1) IS6417A (et)
MX (1) MXPA02006051A (et)
NO (1) NO20022870L (et)
PL (1) PL356032A1 (et)
WO (1) WO2001044192A1 (et)
YU (1) YU44102A (et)
ZA (1) ZA200205566B (et)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2446903B1 (en) 2006-11-20 2019-10-09 President and Fellows of Harvard College Compositions for treating itch
BRPI0909627A2 (pt) * 2008-03-11 2018-04-10 Harvard College métodos, composições e kits para tratar dores e pruridos
US20120172429A1 (en) 2009-07-10 2012-07-05 Woolf Clifford J Permanently charged sodium and calcium channel blockers as anti- inflammatory agents
US10130632B2 (en) 2012-11-27 2018-11-20 Beth Israel Deaconess Medical Center, Inc. Methods for treating renal disease
WO2015120069A1 (en) 2014-02-04 2015-08-13 Beth Israel Deaconess Medical Center, Inc. Methods and kits for the diagnosis and treatment of pancreatic cancer
US11021443B2 (en) 2015-08-03 2021-06-01 President And Fellows Of Harvard College Charged ion channel blockers and methods for use
JP7692834B2 (ja) 2019-03-11 2025-06-16 ノシオン セラピューティクス,インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
MA55320A (fr) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueurs de canaux ioniques substitués par un ester et méthodes d'utilisation
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CA3129111A1 (en) 2019-03-11 2020-09-17 Bridget M. Cole Charged ion channel blockers and methods for use
CN114828845A (zh) 2019-11-06 2022-07-29 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
EP4118070A4 (en) 2020-03-11 2024-04-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI58632C (fi) * 1978-02-07 1981-03-10 Orion Yhtymae Oy Foerfarande foer framstaellning av anilider med antitussiv verkan

Also Published As

Publication number Publication date
HUP0301686A2 (hu) 2003-08-28
IS6417A (is) 2002-06-12
ZA200205566B (en) 2003-11-17
BG106816A (en) 2003-04-30
MXPA02006051A (es) 2004-08-23
KR20020074170A (ko) 2002-09-28
WO2001044192A1 (en) 2001-06-21
YU44102A (sh) 2005-09-19
EP1278731A1 (en) 2003-01-29
AU2334501A (en) 2001-06-25
PL356032A1 (en) 2004-06-14
US20030166629A1 (en) 2003-09-04
JP2003516966A (ja) 2003-05-20
BR0016431A (pt) 2002-10-01
CZ20022095A3 (cs) 2003-02-12
IL150179A0 (en) 2002-12-01
CN1425005A (zh) 2003-06-18
NO20022870D0 (no) 2002-06-14
NO20022870L (no) 2002-08-14

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