EE200200531A - Terapeutiliste rakkusisenevate antikehade saamineja kasutamine - Google Patents

Terapeutiliste rakkusisenevate antikehade saamineja kasutamine

Info

Publication number
EE200200531A
EE200200531A EEP200200531A EEP200200531A EE200200531A EE 200200531 A EE200200531 A EE 200200531A EE P200200531 A EEP200200531 A EE P200200531A EE P200200531 A EEP200200531 A EE P200200531A EE 200200531 A EE200200531 A EE 200200531A
Authority
EE
Estonia
Prior art keywords
production
intracellular antibodies
therapeutic
therapeutic intracellular
antibodies
Prior art date
Application number
EEP200200531A
Other languages
English (en)
Inventor
Valkna Andres
Kogerman Priit
Original Assignee
O� InBio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by O� InBio filed Critical O� InBio
Priority to EEP200200531A priority Critical patent/EE200200531A/et
Priority to AU2003266225A priority patent/AU2003266225A1/en
Priority to CA002499321A priority patent/CA2499321A1/en
Priority to EP03797197A priority patent/EP1539823A1/en
Priority to PCT/EE2003/000005 priority patent/WO2004026911A1/en
Priority to US10/528,073 priority patent/US20080063633A1/en
Publication of EE200200531A publication Critical patent/EE200200531A/et

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • A61K47/6865Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from skin, nerves or brain cancer cell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6889Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6891Pre-targeting systems involving an antibody for targeting specific cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medical Informatics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP200200531A 2002-09-17 2002-09-17 Terapeutiliste rakkusisenevate antikehade saamineja kasutamine EE200200531A (et)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EEP200200531A EE200200531A (et) 2002-09-17 2002-09-17 Terapeutiliste rakkusisenevate antikehade saamineja kasutamine
AU2003266225A AU2003266225A1 (en) 2002-09-17 2003-09-16 Obtaining and use of therapeutic antibodies entering into the cell
CA002499321A CA2499321A1 (en) 2002-09-17 2003-09-16 Obtaining and use of therapeutic antibodies entering into the cell
EP03797197A EP1539823A1 (en) 2002-09-17 2003-09-16 Obtaining and use of therapeutic antibodies entering into the cell
PCT/EE2003/000005 WO2004026911A1 (en) 2002-09-17 2003-09-16 Obtaining and use of therapeutic antibodies entering into the cell
US10/528,073 US20080063633A1 (en) 2002-09-17 2003-09-16 Obtaining and Use of Therapeutic Antibodies Entering Into the Cell

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EEP200200531A EE200200531A (et) 2002-09-17 2002-09-17 Terapeutiliste rakkusisenevate antikehade saamineja kasutamine

Publications (1)

Publication Number Publication Date
EE200200531A true EE200200531A (et) 2004-04-15

Family

ID=32010907

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200531A EE200200531A (et) 2002-09-17 2002-09-17 Terapeutiliste rakkusisenevate antikehade saamineja kasutamine

Country Status (6)

Country Link
US (1) US20080063633A1 (et)
EP (1) EP1539823A1 (et)
AU (1) AU2003266225A1 (et)
CA (1) CA2499321A1 (et)
EE (1) EE200200531A (et)
WO (1) WO2004026911A1 (et)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013504585A (ja) 2009-09-09 2013-02-07 セントローズ, エルエルシー 細胞外標的化薬物複合体
EP2825561A4 (en) * 2012-03-15 2016-03-09 Permeon Biolog Inc CELL PENETRATING COMPOSITIONS FOR THE DISPOSAL OF INTRA-CELLULAR ANTIBODIES AND ANTIBODY-RELATED UNITS AND METHODS OF USE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1263473A (zh) * 1997-05-21 2000-08-16 利兰·斯坦福青年大学托管委员会 增加跨生物膜转运的组合物和方法
US6238876B1 (en) * 1997-06-20 2001-05-29 New York University Methods and materials for the diagnosis and treatment of sporadic basal cell carcinoma
SE9902899D0 (sv) * 1999-08-13 1999-08-13 Karolinska Innovations Ab New peptides, corresponding antibodies, and compositions thereof

Also Published As

Publication number Publication date
US20080063633A1 (en) 2008-03-13
WO2004026911A1 (en) 2004-04-01
EP1539823A1 (en) 2005-06-15
CA2499321A1 (en) 2004-04-01
AU2003266225A1 (en) 2004-04-08

Similar Documents

Publication Publication Date Title
CY2016035I2 (el) Θεραπευτικη χρηση αντισωματων anti-cs1
PL373333A1 (pl) Stosowanie przeciwciał skierowanych przeciw TNFalfa i innego leku
ATE549033T1 (de) Therapeutischer menschlicher monoklonaler anti-il-1r1-antikörper
NO20044402L (no) Kombinasjonsbehandling av kemokine-medierte sykdommer
CY2015015I1 (el) Παραγωγη τιακουμυκινης
PL377931A1 (pl) Farmaceutyczne preparaty donosowe oraz sposoby ich stosowania
NO20033387L (no) Modifiserte antistoffer og fremgangsmåter for anvendelse
EP1581622A4 (en) REMODELING AND GLYCOKON JUGATION OF ERYTHROPOETIN
PL374832A1 (pl) Nowe podstawione benzoimidazolowe postacie dawkowe i sposoby ich stosowania
DE60324099D1 (de) Arzneistoffhaltiger tampon
EP1482984A4 (en) REPLACEMENT ANTIBODIES AND METHOD FOR THEIR MANUFACTURE AND USE
MA28802B1 (fr) Utilisations therapeutiques d'inhibiteurs de rtp801
EE05505B1 (et) Personaalne teraapiasektsioon
DK1537096T3 (da) Derivater af dioxan-2-alkylcarbamater, fremstilling og terapeutisk anvendelse heraf
IS7725A (is) Imidazólópyridín og aðferðir við framleiðslu og notkun þeirra
NO20044916L (no) Preparater av sulfinylacetamid
DK1513836T3 (da) Piperazinylacylpiperidinderivater, fremstilling og terapeutisk anvendelse heraf
EP1478761A4 (en) DEGRADATION OF PESTICIDES AND HYDROPHOBIC ESTERIC TOXINS
IS6967A (is) Ný cýanó-tengd díhýdrópýrimídín efnasambönd og notkun þeirra við meðhöndlun sjúkdóma
DK1556382T3 (da) 3-Phenylpyridoindolderivater, fremstilling og terapeutisk anvendelse deraf
NO20050689L (no) Terapeutisk anvendelse
DE60238174D1 (de) Fluoropolymere und Herstellungs- und Verwendungsverfahren
FI20020360A0 (fi) Biologisesti aktiivisen tuotteen uusi käyttö
EP1646401A4 (en) SPECIFIC HUMAN ANTIBODIES
NO20034172L (no) Bisykliske guanidinderivater og terapeutiske anvendelser derav