EE200200564A - Stavudiini sisaldavad toimeainet aeglustatult vabastavad graanulid - Google Patents
Stavudiini sisaldavad toimeainet aeglustatult vabastavad graanulidInfo
- Publication number
- EE200200564A EE200200564A EEP200200564A EEP200200564A EE200200564A EE 200200564 A EE200200564 A EE 200200564A EE P200200564 A EEP200200564 A EE P200200564A EE P200200564 A EEP200200564 A EE P200200564A EE 200200564 A EE200200564 A EE 200200564A
- Authority
- EE
- Estonia
- Prior art keywords
- sustained
- granules containing
- release granules
- stavudine
- containing stavudine
- Prior art date
Links
- XNKLLVCARDGLGL-JGVFFNPUSA-N Stavudine Chemical compound O=C1NC(=O)C(C)=CN1[C@H]1C=C[C@@H](CO)O1 XNKLLVCARDGLGL-JGVFFNPUSA-N 0.000 title 1
- 239000008187 granular material Substances 0.000 title 1
- 229960001203 stavudine Drugs 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19358800P | 2000-03-30 | 2000-03-30 | |
| PCT/US2001/010078 WO2001074329A2 (en) | 2000-03-30 | 2001-03-29 | Sustained release beadlets containing stavudine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200200564A true EE200200564A (et) | 2004-06-15 |
Family
ID=22714247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200200564A EE200200564A (et) | 2000-03-30 | 2001-03-29 | Stavudiini sisaldavad toimeainet aeglustatult vabastavad graanulid |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7135465B2 (de) |
| EP (1) | EP1267879A2 (de) |
| JP (1) | JP2003528905A (de) |
| KR (1) | KR20030011805A (de) |
| CN (1) | CN1187052C (de) |
| AR (1) | AR027748A1 (de) |
| AU (1) | AU2001249591A1 (de) |
| BG (1) | BG107157A (de) |
| BR (1) | BR0109602A (de) |
| CA (1) | CA2404687A1 (de) |
| CZ (1) | CZ20023003A3 (de) |
| EE (1) | EE200200564A (de) |
| GE (1) | GEP20043285B (de) |
| HU (1) | HUP0302631A2 (de) |
| IL (1) | IL151475A0 (de) |
| LT (1) | LT5045B (de) |
| LV (1) | LV12939B (de) |
| MX (1) | MXPA02009534A (de) |
| NO (1) | NO20024645D0 (de) |
| NZ (1) | NZ522250A (de) |
| PE (1) | PE20011179A1 (de) |
| PL (1) | PL366089A1 (de) |
| RU (1) | RU2239435C2 (de) |
| SK (1) | SK12822002A3 (de) |
| WO (1) | WO2001074329A2 (de) |
| ZA (1) | ZA200207760B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY169670A (en) | 2003-09-03 | 2019-05-08 | Tibotec Pharm Ltd | Combinations of a pyrimidine containing nnrti with rt inhibitors |
| WO2004002398A2 (en) * | 2002-06-27 | 2004-01-08 | Cilag Ag | Spherical pellet containing a water-soluble active ingredient |
| US8802139B2 (en) | 2003-06-26 | 2014-08-12 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
| US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
| US20060024361A1 (en) * | 2004-07-28 | 2006-02-02 | Isa Odidi | Disintegrant assisted controlled release technology |
| US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
| CN100548309C (zh) * | 2004-11-24 | 2009-10-14 | 东北制药总厂 | 司他夫定缓释片剂 |
| TW201414495A (zh) | 2005-04-04 | 2014-04-16 | Tibotec Pharm Ltd | Hiv-感染之預防 |
| EP1898890A1 (de) * | 2005-06-16 | 2008-03-19 | Forest Laboratories, Inc. | Memantin-bead-formulierung mit modifizierter und sofortiger freisetzung |
| WO2007026156A1 (en) * | 2005-08-31 | 2007-03-08 | Cipla Limited | Pharmaceutical combinations containing lamivudine, stavudine and nevirapine |
| GB0525461D0 (en) | 2005-12-15 | 2006-01-25 | Archimedes Dev Ltd | Pharmaceutical compositions |
| US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
| UA96436C2 (ru) | 2006-01-20 | 2011-11-10 | Тиботек Фармасьютикелз Лтд. | Долгосрочное лечение вич-инфекции |
| CN104825397A (zh) | 2006-04-03 | 2015-08-12 | 伊萨·奥迪迪 | 含有机溶胶涂层的受控释放递送物件 |
| US20190083399A9 (en) * | 2006-04-03 | 2019-03-21 | Isa Odidi | Drug delivery composition |
| US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
| AR065720A1 (es) | 2007-03-14 | 2009-06-24 | Tibotec Pharm Ltd | Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso. |
| CN102319181B (zh) * | 2011-09-08 | 2014-07-16 | 广东大华农动物保健品股份有限公司 | 一种微囊型动物药品的包被工艺 |
| US20140271893A1 (en) * | 2013-03-15 | 2014-09-18 | Mcneil-Ppc, Inc. | Coated phenylephrine particles and use thereof in pharmaceutical formulations |
| EP3169314A1 (de) * | 2014-07-17 | 2017-05-24 | Dow Global Technologies LLC | Ethylcellulosedispersion und folie |
| CN105511174A (zh) * | 2016-01-05 | 2016-04-20 | 深圳市华星光电技术有限公司 | 液晶显示面板和显示装置 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4671963A (en) | 1983-10-28 | 1987-06-09 | Germino Felix J | Stearate treated food products |
| US4670270A (en) | 1984-05-07 | 1987-06-02 | Germino Felix J | Stearate treated food products |
| US4940556A (en) | 1986-01-30 | 1990-07-10 | Syntex (U.S.A.) Inc. | Method of preparing long acting formulation |
| US4978655A (en) * | 1986-12-17 | 1990-12-18 | Yale University | Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses |
| GB8707421D0 (en) * | 1987-03-27 | 1987-04-29 | Wellcome Found | Pharmaceutical formulations |
| CA2126441C (en) | 1991-12-30 | 1999-12-21 | David F. Erkoboni | Microcrystalline cellulose spheronization composition |
| US5472711A (en) | 1992-07-30 | 1995-12-05 | Edward Mendell Co., Inc. | Agglomerated hydrophilic complexes with multi-phasic release characteristics |
| US5723490A (en) | 1992-09-08 | 1998-03-03 | Vertex Pharmaceuticals Incorporated | THF-containing sulfonamide inhibitors of aspartyl protease |
| FI101039B (fi) | 1992-10-09 | 1998-04-15 | Eeva Kristoffersson | Menetelmä lääkepellettien valmistamiseksi |
| US5869097A (en) * | 1992-11-02 | 1999-02-09 | Alza Corporation | Method of therapy comprising an osmotic caplet |
| GB9403449D0 (en) | 1994-02-23 | 1994-04-13 | Wellcome Found | Therapeutic benzonitriles |
| EP0749421B1 (de) | 1994-03-07 | 1999-09-15 | Vertex Pharmaceuticals Incorporated | Sulfonamidderivate als aspartylprotease-inhibitoren |
| GB9417249D0 (en) * | 1994-08-26 | 1994-10-19 | Wellcome Found | A novel salt |
| KR19980701739A (ko) | 1995-02-23 | 1998-06-25 | 디르크 반테 | 신경보호제로서 융합된 벤조티아졸의 용도 |
| US6177460B1 (en) | 1995-04-12 | 2001-01-23 | The Procter & Gamble Company | Method of treatment for cancer or viral infections |
| US5691372A (en) | 1995-04-19 | 1997-11-25 | Vertex Pharmaceuticals Incorporated | Oxygenated-Heterocycle containing sulfonamide inhibitors of aspartyl protease |
| US5914332A (en) | 1995-12-13 | 1999-06-22 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| NZ501172A (en) | 1995-12-15 | 2000-04-28 | Cyropreservation Technologies | Composition for organ cryopreservation comprising substituted amides |
| SE9600072D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients II |
| US5883252A (en) | 1996-01-26 | 1999-03-16 | Vertex Pharmaceuticals Incorporated | Aspartyl protease inhibitors |
| US5766623A (en) | 1996-03-25 | 1998-06-16 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University | Compactable self-sealing drug delivery agents |
| US5849911A (en) | 1996-04-22 | 1998-12-15 | Novartis Finance Corporation | Antivirally active heterocyclic azahexane derivatives |
| US5780055A (en) | 1996-09-06 | 1998-07-14 | University Of Maryland, Baltimore | Cushioning beads and tablet comprising the same capable of forming a suspension |
| US5905068A (en) | 1996-09-24 | 1999-05-18 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| CA2269707C (en) | 1996-10-25 | 2005-08-16 | Edward M. Rudnic | Soluble form osmotic dose delivery system |
| US5962462A (en) | 1996-12-13 | 1999-10-05 | Merck & Co., Inc. | Spiro-substituted azacycles as modulators of chemokine receptor activity |
| US5919776A (en) | 1996-12-20 | 1999-07-06 | Merck & Co., Inc. | Substituted aminoquinolines as modulators of chemokine receptor activity |
| US6124319A (en) | 1997-01-21 | 2000-09-26 | Merck & Co., Inc. | 3,3-disubstituted piperidines as modulators of chemokine receptor activity |
| US6136827A (en) | 1997-07-25 | 2000-10-24 | Merck & Co., Inc. | Cyclic amine modulations of chemokine receptor activity |
| PT1003476E (pt) | 1997-08-11 | 2005-05-31 | Alza Corp | Forma de dosagem de agente activo de libertacao prolongada adaptada para retencao gastrica |
| US6166037A (en) | 1997-08-28 | 2000-12-26 | Merck & Co., Inc. | Pyrrolidine and piperidine modulators of chemokine receptor activity |
| US6692767B2 (en) * | 1997-09-19 | 2004-02-17 | Shire Laboratories Inc. | Solid solution beadlet |
| US5904937A (en) | 1997-10-03 | 1999-05-18 | Fmc Corporation | Taste masked pharmaceutical compositions |
| US6180634B1 (en) | 1997-11-13 | 2001-01-30 | Merck & Co., Inc. | Combination therapy for the treatment of AIDS |
| US6013644A (en) | 1997-12-12 | 2000-01-11 | Merck & Co., Inc. | Spiro-substituted azacycles as modulators of chemokine receptor activity |
| AU748064B2 (en) | 1997-12-19 | 2002-05-30 | Takeda Chemical Industries Ltd. | Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative |
| US6140349A (en) | 1998-02-02 | 2000-10-31 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
| US7122207B2 (en) * | 1998-05-22 | 2006-10-17 | Bristol-Myers Squibb Company | High drug load acid labile pharmaceutical composition |
| US6093743A (en) | 1998-06-23 | 2000-07-25 | Medinox Inc. | Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor |
| AU4716299A (en) | 1998-06-24 | 2000-01-10 | Emory University | Use of 3'-azido-2',3'-dideoxyuridine in combination with further anti-hiv drugs for the manufacture of a medicament for the treatment of hiv |
| JP2002540151A (ja) | 1999-03-31 | 2002-11-26 | ザ プロクター アンド ギャンブル カンパニー | ウイルス治療 |
| US6136835A (en) | 1999-05-17 | 2000-10-24 | The Procter & Gamble Company | Methods of treatment for viral infections |
-
2001
- 2001-03-29 EE EEP200200564A patent/EE200200564A/xx unknown
- 2001-03-29 AU AU2001249591A patent/AU2001249591A1/en not_active Abandoned
- 2001-03-29 GE GEAP20016630A patent/GEP20043285B/en unknown
- 2001-03-29 MX MXPA02009534A patent/MXPA02009534A/es not_active Application Discontinuation
- 2001-03-29 BR BR0109602-8A patent/BR0109602A/pt not_active IP Right Cessation
- 2001-03-29 RU RU2002126540/15A patent/RU2239435C2/ru not_active IP Right Cessation
- 2001-03-29 CA CA002404687A patent/CA2404687A1/en not_active Abandoned
- 2001-03-29 CZ CZ20023003A patent/CZ20023003A3/cs unknown
- 2001-03-29 KR KR1020027012769A patent/KR20030011805A/ko not_active Withdrawn
- 2001-03-29 CN CNB018074405A patent/CN1187052C/zh not_active Expired - Fee Related
- 2001-03-29 SK SK1282-2002A patent/SK12822002A3/sk unknown
- 2001-03-29 IL IL15147501A patent/IL151475A0/xx unknown
- 2001-03-29 WO PCT/US2001/010078 patent/WO2001074329A2/en not_active Ceased
- 2001-03-29 EP EP01922832A patent/EP1267879A2/de not_active Withdrawn
- 2001-03-29 NZ NZ522250A patent/NZ522250A/en unknown
- 2001-03-29 US US09/821,103 patent/US7135465B2/en not_active Expired - Lifetime
- 2001-03-29 AR ARP010101516A patent/AR027748A1/es unknown
- 2001-03-29 JP JP2001572074A patent/JP2003528905A/ja active Pending
- 2001-03-29 PL PL01366089A patent/PL366089A1/xx not_active Application Discontinuation
- 2001-03-29 HU HU0302631A patent/HUP0302631A2/hu unknown
- 2001-03-30 PE PE2001000297A patent/PE20011179A1/es not_active Application Discontinuation
-
2002
- 2002-09-06 LT LT2002099A patent/LT5045B/lt not_active IP Right Cessation
- 2002-09-26 ZA ZA200207760A patent/ZA200207760B/en unknown
- 2002-09-27 NO NO20024645A patent/NO20024645D0/no not_active Application Discontinuation
- 2002-09-30 BG BG107157A patent/BG107157A/xx unknown
- 2002-10-25 LV LVP-02-187A patent/LV12939B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20030011805A (ko) | 2003-02-11 |
| JP2003528905A (ja) | 2003-09-30 |
| PL366089A1 (en) | 2005-01-24 |
| MXPA02009534A (es) | 2003-05-14 |
| LT2002099A (en) | 2003-04-25 |
| RU2239435C2 (ru) | 2004-11-10 |
| NO20024645L (no) | 2002-09-27 |
| BG107157A (en) | 2003-06-30 |
| RU2002126540A (ru) | 2004-03-27 |
| US20020002147A1 (en) | 2002-01-03 |
| EP1267879A2 (de) | 2003-01-02 |
| US7135465B2 (en) | 2006-11-14 |
| NZ522250A (en) | 2004-09-24 |
| WO2001074329A2 (en) | 2001-10-11 |
| LV12939B (en) | 2003-04-20 |
| CN1420774A (zh) | 2003-05-28 |
| AR027748A1 (es) | 2003-04-09 |
| LT5045B (lt) | 2003-08-25 |
| CZ20023003A3 (cs) | 2002-11-13 |
| AU2001249591A1 (en) | 2001-10-15 |
| CN1187052C (zh) | 2005-02-02 |
| WO2001074329A3 (en) | 2002-05-10 |
| BR0109602A (pt) | 2004-06-29 |
| NO20024645D0 (no) | 2002-09-27 |
| HUP0302631A2 (hu) | 2003-11-28 |
| SK12822002A3 (sk) | 2003-02-04 |
| CA2404687A1 (en) | 2001-10-11 |
| PE20011179A1 (es) | 2001-12-06 |
| IL151475A0 (en) | 2003-04-10 |
| ZA200207760B (en) | 2004-01-30 |
| GEP20043285B (en) | 2004-07-26 |
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