EE200300244A - 3-aroüülindooli derivaadid ja nende kasutamine CB2-retseptorite agonistidena - Google Patents

3-aroüülindooli derivaadid ja nende kasutamine CB2-retseptorite agonistidena

Info

Publication number: EE200300244A
Authority: EE; Estonia
Prior art keywords: aroylindole; derivatives; receptor agonists; agonists; receptor
Prior art date: 2000-11-22

Application number

EEP200300244A

Other languages

English (en)

Estonian (et)

Inventor

Barth Francis

Congy Christian

Guillaumont Carole

Rinaldi Murielle

Vasse Fabienne

Vernhet Claude

Original Assignee

Sanofi-Synthlabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-22

Filing date

2001-11-21

Publication date

2003-10-15

2001-11-21 Application filed by Sanofi-Synthlabo filed Critical Sanofi-Synthlabo

2003-10-15 Publication of EE200300244A publication Critical patent/EE200300244A/xx

Links

102000009135 CB2 Cannabinoid Receptor Human genes 0.000 title 1
108010073376 CB2 Cannabinoid Receptor Proteins 0.000 title 1
239000000018 receptor agonist Substances 0.000 title 1
229940044601 receptor agonist Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
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Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Cardiology (AREA)
Virology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)
Psychology (AREA)
Dermatology (AREA)
Hospice & Palliative Care (AREA)
AIDS & HIV (AREA)
Ophthalmology & Optometry (AREA)
Obesity (AREA)

EEP200300244A 2000-11-22 2001-11-21 3-aroüülindooli derivaadid ja nende kasutamine CB2-retseptorite agonistidena EE200300244A (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0015158A FR2816938B1 (fr)	2000-11-22	2000-11-22	Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant
PCT/FR2001/003665 WO2002042269A1 (fr)	2000-11-22	2001-11-21	Derives de 3-aroylindole et leur utilisation en tant qu'agonistes des recepteurs cb2

Publications (1)

Publication Number	Publication Date
EE200300244A true EE200300244A (et)	2003-10-15

Family

ID=8856819

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300244A EE200300244A (et)	2000-11-22	2001-11-21	3-aroüülindooli derivaadid ja nende kasutamine CB2-retseptorite agonistidena

Country Status (32)

Country	Link
US (1)	US6995184B2 (cs)
EP (1)	EP1339679B1 (cs)
JP (1)	JP4264258B2 (cs)
KR (1)	KR20030048161A (cs)
CN (1)	CN1234688C (cs)
AR (1)	AR033594A1 (cs)
AT (1)	ATE301638T1 (cs)
AU (1)	AU2002222001A1 (cs)
BG (1)	BG107827A (cs)
BR (1)	BR0115580A (cs)
CA (1)	CA2427444A1 (cs)
CZ (1)	CZ20031392A3 (cs)
DE (1)	DE60112607T2 (cs)
DK (1)	DK1339679T3 (cs)
DZ (1)	DZ3443A1 (cs)
EA (1)	EA005854B1 (cs)
EE (1)	EE200300244A (cs)
ES (1)	ES2247201T3 (cs)
FR (1)	FR2816938B1 (cs)
HR (1)	HRP20030417A2 (cs)
HU (1)	HUP0400561A2 (cs)
IL (1)	IL155634A0 (cs)
IS (1)	IS6802A (cs)
MA (1)	MA26959A1 (cs)
MX (1)	MXPA03004549A (cs)
NO (1)	NO20031952L (cs)
NZ (1)	NZ525609A (cs)
PL (1)	PL362276A1 (cs)
SK (1)	SK6042003A3 (cs)
TW (1)	TWI224592B (cs)
WO (1)	WO2002042269A1 (cs)
ZA (1)	ZA200303728B (cs)

Families Citing this family (37)

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TW200407110A (en) *	2001-11-23	2004-05-16	Astrazeneca Ab	New use for the treatment of gastroesophageal reflux disease
NZ535349A (en)	2002-03-08	2007-01-26	Signal Pharm Inc	JNK inhibitors with chemotherapeutic agents in a combination therapy for treating or preventing cancer and other proliferative disorders in refractory patients in particular
EP1509250B1 (en) *	2002-06-06	2008-05-07	Yissum Research Development Company Of The Hebrew University Of Jerusalem	Methods compositions and articles of manufacture for modulating bone growth
ATE375349T1 (de)	2002-08-02	2007-10-15	Merck & Co Inc	Substituierte furo(2,3-b)pyridin derivate
FR2843964B1 (fr) *	2002-08-29	2004-10-01	Sanofi Synthelabo	Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique
FR2847899B1 (fr)	2002-11-29	2006-04-28	Sanofi Synthelabo	Derives d'indole-3-carboxamide, leur preparation et leur application en therapeutique
FR2854633B1 (fr) *	2003-05-07	2005-06-24	Sanofi Synthelabo	Derives de piperidinyl-et piperazinyl-alkylcarbamates, leur preparation et leur application en therapeutique
FR2856684B1 (fr)	2003-06-26	2008-04-11	Sanofi Synthelabo	Derives de diphenylpyridine, leur preparation et leur application en therapeutique
FR2865205B1 (fr) *	2004-01-16	2006-02-24	Sanofi Synthelabo	Derives de type aryloxyalkylcarbamates, leur preparation et leur application en therapeutique
WO2005123053A2 (en) *	2004-06-22	2005-12-29	Pharmos Limited	Use of cb2 receptors agonists for the treatment of huntington’s disease
CA2586011C (en)	2004-07-12	2011-07-19	Cadila Healthcare Limited	Tricyclic pyrazole derivatives as cannabinoid receptor modulators
US20060025448A1 (en)	2004-07-22	2006-02-02	Cadila Healthcare Limited	Hair growth stimulators
JP2008520719A (ja) *	2004-11-22	2008-06-19	スレショルドファーマシューティカルズインコーポレイティッド	チューブリン結合抗癌剤およびそれらのプロドラッグ
JP4922946B2 (ja) *	2004-12-21	2012-04-25	アボット・ラボラトリーズ	カンナビノイド受容体リガンドとしての３−シクロアルキルカルボニルインドール類
FR2893615B1 (fr) *	2005-11-18	2008-03-07	Sanofi Aventis Sa	Derives de 3-acylindole, leur preparation et leur application en therapeutique
RU2306906C1 (ru) *	2006-04-21	2007-09-27	Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по здравоохранению и социальному развитию"	Способ повышения зрительных функций при сублюксации хрусталика в случаях нарушения обмена в системе соединительной ткани
EP2024349B1 (en)	2006-05-31	2017-08-02	AbbVie Inc.	Compounds as cannabinoid receptor ligands and uses thereof
US8841334B2 (en)	2006-05-31	2014-09-23	Abbvie Inc.	Compounds as cannabinoid receptor ligands and uses thereof
GB0702862D0 (en) *	2007-02-14	2007-03-28	Univ Aberdeen	Therapeutic compounds
JP2010522760A (ja)	2007-03-28	2010-07-08	アボット・ラボラトリーズ	カンナビノイド受容体リガンドとしての１，３−チアゾール−２（３ｈ）−イリデン化合物
US7872033B2 (en) *	2007-04-17	2011-01-18	Abbott Laboratories	Compounds as cannabinoid receptor ligands
FR2915199B1 (fr) *	2007-04-18	2010-01-22	Sanofi Aventis	Derives de triazolopyridine-carboxamides et triazolopyrimidine-carboxamides, leur preparation et leur application en therapeutique.
WO2008144360A1 (en)	2007-05-18	2008-11-27	Abbott Laboratories	Novel compounds as cannabinoid receptor ligands
US9193713B2 (en) *	2007-10-12	2015-11-24	Abbvie Inc.	Compounds as cannabinoid receptor ligands
FR2933697B1 (fr) *	2008-07-11	2010-08-13	Sanofi Aventis	Derives de 1-benzyl-cinnolin-4-(1h)-one substitues, leur preparation et leur application en therapeutique
US8846730B2 (en)	2008-09-08	2014-09-30	Abbvie Inc.	Compounds as cannabinoid receptor ligands
CA2737199A1 (en) *	2008-09-16	2010-03-25	Abbott Laboratories	Novel compounds as cannabinoid receptor ligands
PA8854001A1 (es)	2008-12-16	2010-07-27	Abbott Lab	Compuestos novedosos como ligandos de receptores de canabinoides
FR2941696B1 (fr)	2009-02-05	2011-04-15	Sanofi Aventis	Derives d'azaspiranyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
FR2945533B1 (fr)	2009-05-12	2011-05-27	Sanofi Aventis	Derives de cyclopenta°c!pyrrolyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
EP2456428A1 (en)	2009-07-23	2012-05-30	INSERM - Institut National de la Santé et de la Recherche Médicale	Selective cb2 receptor agonists for use in the prevention or treatment of alcoholic liver disease
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2000
- 2000-11-22 FR FR0015158A patent/FR2816938B1/fr not_active Expired - Fee Related
2001
- 2001-11-21 US US10/416,617 patent/US6995184B2/en not_active Expired - Fee Related
- 2001-11-21 EP EP01997476A patent/EP1339679B1/fr not_active Expired - Lifetime
- 2001-11-21 IL IL15563401A patent/IL155634A0/xx unknown
- 2001-11-21 JP JP2002544405A patent/JP4264258B2/ja not_active Expired - Fee Related
- 2001-11-21 HR HR20030417A patent/HRP20030417A2/hr not_active Application Discontinuation
- 2001-11-21 DK DK01997476T patent/DK1339679T3/da active
- 2001-11-21 AT AT01997476T patent/ATE301638T1/de not_active IP Right Cessation
- 2001-11-21 EE EEP200300244A patent/EE200300244A/xx unknown
- 2001-11-21 HU HU0400561A patent/HUP0400561A2/hu unknown
- 2001-11-21 DE DE60112607T patent/DE60112607T2/de not_active Expired - Lifetime
- 2001-11-21 AR ARP010105425A patent/AR033594A1/es not_active Application Discontinuation
- 2001-11-21 ES ES01997476T patent/ES2247201T3/es not_active Expired - Lifetime
- 2001-11-21 MX MXPA03004549A patent/MXPA03004549A/es active IP Right Grant
- 2001-11-21 CZ CZ20031392A patent/CZ20031392A3/cs unknown
- 2001-11-21 PL PL01362276A patent/PL362276A1/xx not_active Application Discontinuation
- 2001-11-21 AU AU2002222001A patent/AU2002222001A1/en not_active Abandoned
- 2001-11-21 EA EA200300453A patent/EA005854B1/ru not_active IP Right Cessation
- 2001-11-21 KR KR10-2003-7006862A patent/KR20030048161A/ko not_active Withdrawn
- 2001-11-21 CN CNB018211755A patent/CN1234688C/zh not_active Expired - Fee Related
- 2001-11-21 BR BR0115580-6A patent/BR0115580A/pt not_active IP Right Cessation
- 2001-11-21 CA CA002427444A patent/CA2427444A1/fr not_active Abandoned
- 2001-11-21 WO PCT/FR2001/003665 patent/WO2002042269A1/fr not_active Ceased
- 2001-11-21 NZ NZ525609A patent/NZ525609A/en unknown
- 2001-11-21 SK SK604-2003A patent/SK6042003A3/sk unknown
- 2001-11-21 DZ DZ013443A patent/DZ3443A1/fr active
- 2001-11-22 TW TW090128947A patent/TWI224592B/zh active
2003
- 2003-04-29 NO NO20031952A patent/NO20031952L/no unknown
- 2003-04-30 IS IS6802A patent/IS6802A/is unknown
- 2003-05-13 MA MA27157A patent/MA26959A1/fr unknown
- 2003-05-14 ZA ZA200303728A patent/ZA200303728B/en unknown
- 2003-05-19 BG BG107827A patent/BG107827A/bg unknown

Also Published As

Publication number	Publication date
DK1339679T3 (da)	2005-12-12
CN1234688C (zh)	2006-01-04
BR0115580A (pt)	2003-09-09
AU2002222001A1 (en)	2002-06-03
CZ20031392A3 (cs)	2003-09-17
NO20031952D0 (no)	2003-04-29
NO20031952L (no)	2003-07-22
CA2427444A1 (fr)	2002-05-30
DZ3443A1 (fr)	2002-05-30
CN1483023A (zh)	2004-03-17
EP1339679A1 (fr)	2003-09-03
AR033594A1 (es)	2003-12-26
BG107827A (bg)	2004-01-30
IS6802A (is)	2003-04-30
JP4264258B2 (ja)	2009-05-13
ZA200303728B (en)	2004-05-14
WO2002042269A1 (fr)	2002-05-30
EA005854B1 (ru)	2005-06-30
HUP0400561A2 (hu)	2004-07-28
MXPA03004549A (es)	2004-03-26
FR2816938B1 (fr)	2003-01-03
PL362276A1 (en)	2004-10-18
US6995184B2 (en)	2006-02-07
JP2004514668A (ja)	2004-05-20
NZ525609A (en)	2004-11-26
DE60112607T2 (de)	2006-06-14
DE60112607D1 (de)	2005-09-15
HRP20030417A2 (en)	2003-08-31
KR20030048161A (ko)	2003-06-18
EP1339679B1 (fr)	2005-08-10
EA200300453A1 (ru)	2003-10-30
IL155634A0 (en)	2003-11-23
TWI224592B (en)	2004-12-01
FR2816938A1 (fr)	2002-05-24
MA26959A1 (fr)	2004-12-20
ES2247201T3 (es)	2006-03-01
SK6042003A3 (en)	2003-12-02
US20040034090A1 (en)	2004-02-19
ATE301638T1 (de)	2005-08-15

Legal Events

Date	Code	Title	Description
2005-02-15	HC1A	Change of owner name

Publication	Publication Date	Title
IS6802A (is)	2003-04-30	3-arýlindólafleiður og notkun þeirra sem CB2 viðtakagerandefni
EE200200251A (et)	2003-06-16	Uued N-asabitsükloamiidi derivaadid ja nende kasutamine
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ATE298332T1 (de)	2005-07-15	Decahydro-isochinolinderivate
DE50114491D1 (de)	2008-12-24	Substituierte C-Cyclohexylmethylamin-Derivative
EE200200135A (et)	2003-04-15	D4 antagonistidena toimivad tienoisoksasolüül- jatienüülpürrasolüülfenoksü-asendatud propüülderivaadid
ATE282021T1 (de)	2004-11-15	Substituierte aminomethyl-phenyl- cyclohexanderivate
ATE272045T1 (de)	2004-08-15	Substituierte 1-aminobutan-3-ol-derivate
PT1351959E (pt)	2005-09-30	Novos derivados de pleuromutilina
DK1246791T3 (da)	2005-02-14	Aminomethyl-phenyl-cyklohexanonderivater
DE60141206D1 (de)	2010-03-18	Anilin-derivate
ATE361274T1 (de)	2007-05-15	Substituierte 5-amino-1-penten-3-ol-derivate
ATE374776T1 (de)	2007-10-15	Pyrrolotriazolopyrimidinonderivate
NO20021249L (no)	2002-05-10	Tienoisoksazolfenoksyusubstituerte etyl- og propylderivater anvendbare som D4antagonister
HK1055961A (en)	2004-01-30	3-arylindole derivatives and their use as cb2 receptor agonists
DK1246793T3 (da)	2005-02-21	Substituerede aminomethyl-phenyl-cyclohexanderivater