EE201100037A - Use of microRNAs as biomarkers and targets for influencing cell proliferative properties and a method and kit for detecting their expression level - Google Patents

Use of microRNAs as biomarkers and targets for influencing cell proliferative properties and a method and kit for detecting their expression level

Info

Publication number
EE201100037A
EE201100037A EEP201100037A EEP201100037A EE201100037A EE 201100037 A EE201100037 A EE 201100037A EE P201100037 A EEP201100037 A EE P201100037A EE P201100037 A EEP201100037 A EE P201100037A EE 201100037 A EE201100037 A EE 201100037A
Authority
EE
Estonia
Prior art keywords
micrornas
biomarkers
targets
kit
detecting
Prior art date
Application number
EEP201100037A
Other languages
Estonian (et)
Inventor
Rebane Ana
Tserel Liina
Runnel Toomas
Kisand Kai
Pihlap Maire
Original Assignee
Tartu Ülikool
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tartu Ülikool filed Critical Tartu Ülikool
Priority to EEP201100037A priority Critical patent/EE201100037A/en
Priority to PCT/EP2012/059186 priority patent/WO2012156473A2/en
Publication of EE201100037A publication Critical patent/EE201100037A/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26DCUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D3/00Cutting work characterised by the nature of the cut made; Apparatus therefor
    • B26D3/18Cutting work characterised by the nature of the cut made; Apparatus therefor to obtain cubes or the like
    • B26D3/185Grid like cutters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26DCUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D5/00Arrangements for operating and controlling machines or devices for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
    • B26D5/08Means for actuating the cutting member to effect the cut
    • B26D5/10Hand or foot actuated means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26DCUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D3/00Cutting work characterised by the nature of the cut made; Apparatus therefor
    • B26D3/18Cutting work characterised by the nature of the cut made; Apparatus therefor to obtain cubes or the like
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26DCUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D5/00Arrangements for operating and controlling machines or devices for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
    • B26D5/08Means for actuating the cutting member to effect the cut
    • B26D5/18Toggle-link means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26DCUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D7/00Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
    • B26D7/06Arrangements for feeding or delivering work of other than sheet, web, or filamentary form
    • B26D7/0608Arrangements for feeding or delivering work of other than sheet, web, or filamentary form by pushers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26DCUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D7/00Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
    • B26D7/18Means for removing cut-out material or waste
    • B26D7/1818Means for removing cut-out material or waste by pushing out
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Forests & Forestry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP201100037A 2011-05-16 2011-05-16 Use of microRNAs as biomarkers and targets for influencing cell proliferative properties and a method and kit for detecting their expression level EE201100037A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EEP201100037A EE201100037A (en) 2011-05-16 2011-05-16 Use of microRNAs as biomarkers and targets for influencing cell proliferative properties and a method and kit for detecting their expression level
PCT/EP2012/059186 WO2012156473A2 (en) 2011-05-16 2012-05-16 A set of micrornas as markers and targets in cancer and immune system related diseases, methods for their application and a kit

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EEP201100037A EE201100037A (en) 2011-05-16 2011-05-16 Use of microRNAs as biomarkers and targets for influencing cell proliferative properties and a method and kit for detecting their expression level

Publications (1)

Publication Number Publication Date
EE201100037A true EE201100037A (en) 2012-12-17

Family

ID=45937266

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP201100037A EE201100037A (en) 2011-05-16 2011-05-16 Use of microRNAs as biomarkers and targets for influencing cell proliferative properties and a method and kit for detecting their expression level

Country Status (2)

Country Link
EE (1) EE201100037A (en)
WO (1) WO2012156473A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106957894A (en) * 2016-01-11 2017-07-18 中国医学科学院肿瘤医院 MicroRNA molecule express spectra is used to predict the purposes that brain transplantation of non small cell Lung shifts risk
CN107137701B (en) * 2017-05-07 2020-07-14 山东兴瑞生物科技有限公司 Gene target and inhibitor for improving anti-liver cancer effect of DC vaccine and DC tumor vaccine
CN108125976B (en) * 2017-12-29 2020-07-31 唐山市人民医院 Molecular marker miR-4270 for predicting brain metastases from lung cancer and its application in drugs and diagnostic kits
CN111053789A (en) * 2019-11-26 2020-04-24 湖南营养树生物科技有限公司 Methods and compositions for modulating the immune system

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004032196A1 (en) 2004-07-02 2006-02-02 Strasser, Wolfgang, Dr.med. Test kit and pressure-sensitive adhesive tape for a cytological examination of the skin surface
EP2338994B1 (en) * 2004-09-02 2014-03-19 Yale University Regulation of oncogenes by microRNAs
EP2302055B1 (en) * 2004-11-12 2014-08-27 Asuragen, Inc. Methods and compositions involving miRNA and miRNA inhibitor molecules
EP2295598A4 (en) 2008-05-07 2013-06-12 Univ Sapporo Medical METHOD AND KIT FOR DETECTING CANCER, AND THERAPEUTIC AGENT FOR CANCER
US9394538B2 (en) 2008-05-07 2016-07-19 Shi-Lung Lin Development of universal cancer drugs and vaccines
WO2010056737A2 (en) * 2008-11-11 2010-05-20 Mirna Therapeutics, Inc. Methods and compositions involving mirnas in cancer stem cells
US20130177624A1 (en) 2009-05-08 2013-07-11 David Brian Corry Mirna expression in allergic disease
CN102725632A (en) 2009-08-28 2012-10-10 奥斯瑞根公司 MiRNA biomarkers of lung disease
ITMI20091538A1 (en) 2009-09-07 2011-03-08 Istituto Naz Di Genetica Mole Colare Ingm PROFILES OF EXPRESSION OF MICRO-RNA IN THE PERIPHERAL BLOOD OF PATIENTS WITH HEPATOCARCINOMA OR HEPATIC CIRROSIS AND THEIR USES

Also Published As

Publication number Publication date
WO2012156473A3 (en) 2013-03-07
WO2012156473A2 (en) 2012-11-22

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