EE9900560A - 5-Naphthalen-1-yl-1,3-dioxane derivatives, their preparation and therapeutic use - Google Patents

5-Naphthalen-1-yl-1,3-dioxane derivatives, their preparation and therapeutic use

Info

Publication number
EE9900560A
EE9900560A EEP199900560A EEP9900560A EE9900560A EE 9900560 A EE9900560 A EE 9900560A EE P199900560 A EEP199900560 A EE P199900560A EE P9900560 A EEP9900560 A EE P9900560A EE 9900560 A EE9900560 A EE 9900560A
Authority
EE
Estonia
Prior art keywords
naphthalen
preparation
therapeutic use
dioxane derivatives
dioxane
Prior art date
Application number
EEP199900560A
Other languages
Estonian (et)
Inventor
Dargazanli Gihad
Lardenois Patrick
Frost Jonathan
George Pascal
Original Assignee
Sanofi-Synthlabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9706946A external-priority patent/FR2764289B1/en
Priority claimed from FR9706947A external-priority patent/FR2764291B1/en
Priority claimed from FR9706945A external-priority patent/FR2764288B1/en
Priority claimed from FR9706944A external-priority patent/FR2764287B1/en
Application filed by Sanofi-Synthlabo filed Critical Sanofi-Synthlabo
Publication of EE9900560A publication Critical patent/EE9900560A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
EEP199900560A 1997-06-05 1998-06-03 5-Naphthalen-1-yl-1,3-dioxane derivatives, their preparation and therapeutic use EE9900560A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR9706946A FR2764289B1 (en) 1997-06-05 1997-06-05 5-NAPHTALEN-1-YL-1,3-DIOXANE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR9706947A FR2764291B1 (en) 1997-06-05 1997-06-05 5-NAPHTALEN-1-YL-1,3-DIOXANE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR9706945A FR2764288B1 (en) 1997-06-05 1997-06-05 5-NAPHTALEN-1-YL-1,3-DIOXANE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR9706944A FR2764287B1 (en) 1997-06-05 1997-06-05 5-NAPHTALEN-1-YL-1,3-DIOXANES DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
PCT/FR1998/001113 WO1998055474A1 (en) 1997-06-05 1998-06-03 5-naphthalen-1-yl-1,3-dioxane derivatives, preparation and therapeutic application

Publications (1)

Publication Number Publication Date
EE9900560A true EE9900560A (en) 2000-06-15

Family

ID=27447000

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900560A EE9900560A (en) 1997-06-05 1998-06-03 5-Naphthalen-1-yl-1,3-dioxane derivatives, their preparation and therapeutic use

Country Status (18)

Country Link
EP (1) EP0986552A1 (en)
JP (1) JP2002502412A (en)
KR (1) KR20010013435A (en)
CN (1) CN1265658A (en)
AR (1) AR012908A1 (en)
AU (1) AU8025198A (en)
BG (1) BG103937A (en)
BR (1) BR9810742A (en)
CA (1) CA2290695A1 (en)
CO (1) CO4940480A1 (en)
EE (1) EE9900560A (en)
HU (1) HUP0002166A3 (en)
IL (1) IL133242A0 (en)
NO (1) NO995966L (en)
PL (1) PL337234A1 (en)
SK (1) SK166199A3 (en)
TR (1) TR199903022T2 (en)
WO (1) WO1998055474A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7349301A (en) * 2000-07-21 2002-02-05 Ortho Mcneil Pharm Inc Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
FR2843964B1 (en) 2002-08-29 2004-10-01 Sanofi Synthelabo DIOXANE-2-ALKYLCARBAMATES DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE111460T1 (en) * 1990-06-15 1994-09-15 Synthelabo 2-(AMINOALKYL)-5-(ARYLALKYL)1,3-DIOXANE DERIVATIVES, THEIR PRODUCTION AND APPLICATIONS IN THERAPEUTICS.
FR2714055B1 (en) * 1993-12-22 1996-01-19 Synthelabo Derivatives of 5- (arylalkyl) -1,3-dioxane substituted in position 2, their preparation and their use in therapy.
FR2742152B1 (en) * 1995-12-06 1998-01-16 Synthelabo 5-NAPHTALEN-1-YL-1,3-DIOXANES DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Also Published As

Publication number Publication date
NO995966L (en) 2000-02-04
AU8025198A (en) 1998-12-21
EP0986552A1 (en) 2000-03-22
BR9810742A (en) 2000-09-12
HUP0002166A2 (en) 2001-06-28
BG103937A (en) 2000-07-31
WO1998055474A1 (en) 1998-12-10
JP2002502412A (en) 2002-01-22
SK166199A3 (en) 2000-06-12
HUP0002166A3 (en) 2002-12-28
CA2290695A1 (en) 1998-12-10
IL133242A0 (en) 2001-03-19
TR199903022T2 (en) 2000-04-21
AR012908A1 (en) 2000-11-22
CN1265658A (en) 2000-09-06
NO995966D0 (en) 1999-12-03
CO4940480A1 (en) 2000-07-24
KR20010013435A (en) 2001-02-26
PL337234A1 (en) 2000-08-14

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