EG24885A - Substituted 4-nitroimidazole compound and process for producing the same - Google Patents

Substituted 4-nitroimidazole compound and process for producing the same

Info

Publication number
EG24885A
EG24885A EGNA2005000131A EG24885A EG 24885 A EG24885 A EG 24885A EG NA2005000131 A EGNA2005000131 A EG NA2005000131A EG 24885 A EG24885 A EG 24885A
Authority
EG
Egypt
Prior art keywords
substituted
producing
same
nitroimidazole compound
nitroimidazole
Prior art date
Application number
Other languages
English (en)
Inventor
Fumitaka Goto
Noriaki Takemura
Otani Tadaaki
Takeshi Hasegawa
Hidetsugu Tsubouchi
Naoto Utsumi
Shigekazu Fujita
Hideaki Kuroda
Takuya Shitsuta
Hirofumi Sasaki
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of EG24885A publication Critical patent/EG24885A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EGNA2005000131 2002-10-15 2005-04-12 Substituted 4-nitroimidazole compound and process for producing the same EG24885A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002299896 2002-10-15
JP2003037914 2003-02-17
PCT/JP2003/013134 WO2004035547A1 (ja) 2002-10-15 2003-10-14 １位置換―４―ニトロイミダゾール化合物及びその製造法

Publications (1)

Publication Number Publication Date
EG24885A true EG24885A (en) 2010-12-06

Family

ID=32109445

Family Applications (1)

Application Number Title Priority Date Filing Date
EGNA2005000131 EG24885A (en) 2002-10-15 2005-04-12 Substituted 4-nitroimidazole compound and process for producing the same

Country Status (16)

Country Link
US (4) US7368579B2 (de)
EP (2) EP1553088A4 (de)
JP (1) JP5014315B2 (de)
KR (1) KR100655670B1 (de)
AR (1) AR041605A1 (de)
AU (1) AU2003301282B2 (de)
BR (1) BR0313566A (de)
CA (1) CA2494710C (de)
EG (1) EG24885A (de)
ES (1) ES2526892T3 (de)
MX (1) MXPA05002414A (de)
MY (1) MY145079A (de)
PL (1) PL375103A1 (de)
RU (1) RU2324682C2 (de)
TW (2) TWI331607B (de)
WO (1) WO2004035547A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2494710C (en) * 2002-10-15 2011-05-03 Otsuka Pharmaceutical Co., Ltd. 1-substituted-4-nitroimidazole compound and method for preparing the same
PT1678185E (pt) * 2003-10-31 2009-01-13 Otsuka Pharma Co Ltd Compostos 2,3-di-hidro-6-nitroimidazo[2,1-b]oxazole para o tratamento da tuberculose
TWI300409B (en) * 2004-02-18 2008-09-01 Otsuka Pharma Co Ltd Method for producing 4-nitroimidazole compound
TW200624422A (en) * 2004-09-27 2006-07-16 Otsuka Pharma Co Ltd Process for production of 2-chloro-4-nitroimidazole
CN100338039C (zh) * 2004-11-29 2007-09-19 南京圣和药业有限公司 奥硝唑光学对映体的制备及纯化方法
PT1906926E (pt) 2005-07-28 2011-01-26 Otsuka Pharma Co Ltd Composição farmacêutica que contém derivados de 2,3-di-hidro-6-nitroimidazo[2,1-b]oxazole
AR070301A1 (es) * 2007-05-08 2010-03-31 Otsuka Pharma Co Ltd Compuesto epoxi y metodo para producir el mismo
EP2323990B1 (de) * 2008-08-21 2014-06-18 Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Verfahren zur herstellung von 2-halogeno-4-nitroimidazolen
TW201200523A (en) 2010-01-29 2012-01-01 Otsuka Pharma Co Ltd Synthetic intermediate of oxazole compound and method for producing the same
WO2014014845A1 (en) 2012-07-18 2014-01-23 Vertex Pharmaceuticals Incorporated Combination therapy comprising|1 -ethyl-3-[5-[2-{1 -hydroxy-1 -methyl-ethyl}pyrimidin-5-yl]-7-(tetra hydrofuran-2-|yl}-1 h-benzimidazol-2-yl]urea and derivatives thereof to treat mycobacterium|diseases
CN103396369B (zh) * 2013-08-14 2016-03-23 盐城工学院 一种制备2-氯-4-硝基咪唑的方法
AU2018260098A1 (en) 2017-04-26 2019-10-31 Basf Se Substituted succinimide derivatives as pesticides
EP3696177A1 (de) 2019-02-12 2020-08-19 Basf Se Heterocyclische verbindungen zur bekämpfung von wirbellosen schädlingen
WO2020202205A1 (en) * 2019-04-01 2020-10-08 Council Of Scientific And Industrial Research Process for the preparation of derivatives of 1,1-dialkylethane-1,2-diols as useful intermediates
EP3962903A1 (de) 2019-05-01 2022-03-09 Boehringer Ingelheim International GmbH (r)-(2-methyloxiran-2-yl)methyl 4-bromobenzolsulfonat
TW202339719A (zh) 2021-12-14 2023-10-16 德商百靈佳殷格翰國際股份有限公司 用於治療慢性腎臟病之醛固酮合成酶抑制劑

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU143401A1 (ru) * 1961-02-03 1961-11-30 П.М. Кочергин Способ получени нитрохлоримидазолов
US3341548A (en) * 1964-04-29 1967-09-12 Hoffmann La Roche Nitroimidazoles and their preparation
US3435049A (en) * 1965-05-19 1969-03-25 Hoffmann La Roche Nitroimidazole derivatives
DE2414280C2 (de) * 1974-03-25 1981-12-17 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 1-Methyl-5-nitroimidazolen
CH605811A5 (de) * 1974-04-19 1978-10-13 Crc Ricerca Chim
US4183941A (en) 1978-08-21 1980-01-15 John R. A. Simoons Treatment of rheumatoid arthritis and related diseases
AR245935A1 (es) * 1988-01-15 1994-03-30 Rhone Poulenc Sante Procedimiento para la preparacion de alquil-1 nitro-5 imidazoles.
US5344937A (en) * 1993-04-20 1994-09-06 Eli Lilly And Company Alkyl substituted nitroimidazole acetic acids
US5668127A (en) 1995-06-26 1997-09-16 Pathogenesis Corporation Nitroimidazole antibacterial compounds and methods of use thereof
AR041198A1 (es) * 2002-10-11 2005-05-04 Otsuka Pharma Co Ltd Compuesto 2,3-dihidro-6-nitroimidazo[2,1-b] oxaxol, y composiciones farmaceuticas que lo contienen
CA2494710C (en) * 2002-10-15 2011-05-03 Otsuka Pharmaceutical Co., Ltd. 1-substituted-4-nitroimidazole compound and method for preparing the same
TWI300409B (en) * 2004-02-18 2008-09-01 Otsuka Pharma Co Ltd Method for producing 4-nitroimidazole compound

Also Published As

Publication number Publication date
US20080200689A1 (en) 2008-08-21
KR20050046013A (ko) 2005-05-17
RU2005114534A (ru) 2006-01-20
TW200410943A (en) 2004-07-01
US7368579B2 (en) 2008-05-06
BR0313566A (pt) 2005-06-21
US20120130082A1 (en) 2012-05-24
JP5014315B2 (ja) 2012-08-29
MY145079A (en) 2011-12-15
US20060079697A1 (en) 2006-04-13
US20080097107A1 (en) 2008-04-24
CA2494710A1 (en) 2004-04-29
PL375103A1 (en) 2005-11-28
AU2003301282B2 (en) 2009-04-30
US8129544B2 (en) 2012-03-06
EP2644599A1 (de) 2013-10-02
MXPA05002414A (es) 2005-06-22
AU2003301282A1 (en) 2004-05-04
RU2324682C2 (ru) 2008-05-20
EP1553088A1 (de) 2005-07-13
TW200838855A (en) 2008-10-01
WO2004035547A1 (ja) 2004-04-29
JP2009102329A (ja) 2009-05-14
HK1188993A1 (en) 2014-05-23
EP2644599B1 (de) 2014-12-10
US7807843B2 (en) 2010-10-05
HK1083830A1 (en) 2006-08-11
ES2526892T3 (es) 2015-01-16
KR100655670B1 (ko) 2007-02-28
AR041605A1 (es) 2005-05-26
CA2494710C (en) 2011-05-03
EP1553088A4 (de) 2011-03-02
TWI331607B (en) 2010-10-11

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