EP0034096A1 - Kreislauf zum Belüften und Filtern der Atmosphäre in einem abgedichteten Raum - Google Patents

Kreislauf zum Belüften und Filtern der Atmosphäre in einem abgedichteten Raum Download PDF

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Publication number
EP0034096A1
EP0034096A1 EP81400177A EP81400177A EP0034096A1 EP 0034096 A1 EP0034096 A1 EP 0034096A1 EP 81400177 A EP81400177 A EP 81400177A EP 81400177 A EP81400177 A EP 81400177A EP 0034096 A1 EP0034096 A1 EP 0034096A1
Authority
EP
European Patent Office
Prior art keywords
enclosure
filtration
ventilation
circuit
establishing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP81400177A
Other languages
English (en)
French (fr)
Other versions
EP0034096B1 (de
Inventor
Claude Picard
Bernard Saint Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Getinge Life Science France SAS
Original Assignee
La Calhene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by La Calhene SA filed Critical La Calhene SA
Publication of EP0034096A1 publication Critical patent/EP0034096A1/de
Application granted granted Critical
Publication of EP0034096B1 publication Critical patent/EP0034096B1/de
Expired legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
    • G21F7/00—Shielded cells or rooms
    • G21F7/04—Shielded glove-boxes
    • G21F7/041—Glove-box atmosphere, temperature or pressure control devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers
    • B01L1/02—Air-pressure chambers; Air-locks therefor
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F3/00—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
    • F24F3/12—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling
    • F24F3/16—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by purification, e.g. by filtering; by sterilisation; by ozonisation
    • F24F3/167—Clean rooms, i.e. enclosed spaces in which a uniform flow of filtered air is distributed

Definitions

  • the present invention relates to a circuit for ventilation and filtration of the medium contained in a sealed enclosure, this circuit comprising a main circuit and an emergency circuit making it possible to ensure ventilation and filtration in the event of failure of the main circuit or in the event of rupture of the sealing of the enclosure.
  • the invention applies to the case where the medium contained in the enclosure presents risks of contamination for people located nearby. This is particularly the case when the sealed enclosure is used to carry out biological experiments or manipulations, for example on viruses or bacteria, or when the products contained in the enclosure are radioactive products.
  • the protection of the personnel in the event of micro-leakage in the enclosure is obtained by establishing a permanent depression inside it.
  • This depression is generally established by means of a motor-fan arranged in an outlet pipe further equipped with filtration means making it possible to reject the gases without the latter being contaminated.
  • the outlet pipe can lead to the outside of the building in which the confinement enclosure is located, in particular in order to avoid that residual vapors leaving the enclosure, for example during sterilizations, inconvenience the personnel present in the room.
  • This outlet pipe making it possible to establish a vacuum inside the enclosure is generally associated with an inlet pipe equipped with filtration means and in which the flow is regulated.
  • this inlet pipe allows to regularly renew the medium contained in the enclosure. Such renewal is necessary when calories or a gas such as water vapor are released inside the enclosure, for example by a motor or an oven, or when living beings present inside the enclosure requires the regular supply of a certain volume of fresh air.
  • the object of the present invention is to maintain the vacuum inside the enclosure and to continue to ensure the renewal of the medium contained in the enclosure in the event of a circuit failure.
  • normal ventilation for example from an engine shutdown, or in the event of a leak occurring in the enclosure.
  • the subject of the present invention is the production of a ventilation and filtration circuit making it possible to obtain this result without the need to provide two complete and independent circuits, that is to say without increasing too costly the cost of installation.
  • a circuit for ventilation and filtration of the medium contained in a sealed enclosure comprising an inlet pipe equipped with means for regulating the flow rate and with filtration means, and a pipe for outlet equipped with filtration means and means for establishing a vacuum inside the enclosure, characterized in that it comprises second means for establishing a vacuum inside the enclosure, arranged in the pipe of entry upstream of the filtration means.
  • the ventilation and filtration circuit further comprises means for detecting a fall in the vacuum prevailing inside the enclosure automatically controlling the implementation of the second means for establishing a depression inside the enclosure.
  • the detection means can be constituted by a pressure switch which communicates with the enclosure by a pipe in which are arranged filtration means and means for interrupting the communication between the enclosure and the pressure switch, in particular when it is necessary to sterilize the medium contained in the enclosure.
  • the power of the second means for establishing a vacuum inside the enclosure is greater than the power of the first means for establishing a vacuum inside the enclosure, so that this vacuum remains at an acceptable level even in case of rupture of the enclosure seal.
  • a sterilization device can be connected to the inlet pipe between the filtration means and the second means for establishing a vacuum inside the enclosure.
  • the single figure shows a sealed enclosure 10 isolating air in a sterile environment from the surrounding atmosphere.
  • An enclosure of the type of enclosure 10 can in particular be used in order to carry out biological experiments or manipulations, for example on viruses or bacteria, or even to work on radioactive products.
  • a permanent depression is created inside the enclosure by means of an outlet pipe 12 through which the air contained in the enclosure is sucked by means of a suction fan 14 which rejects this air into the atmosphere, outside the building in which the enclosure 10 is located in order to protect the personnel from the residual vapors which leave of the enclosure, in particular in the event of sterilization.
  • Two air filters 16, of the absolute type are placed in the pipe 12 at the outlet of the enclosure 10, so as to retain the contaminating products such as bacteria or viruses which are present in the enclosure.
  • each of the filters 16 can be made of sandpaper and mounted inside a sealed metallic or plastic casing. Each filter has an efficiency of 99.99% for particles of 0.3u.
  • a full-flow valve 18 is placed in the line 12 between the fan 14 and the filters 16 so to regulate the depression inside the enclosure during sterilizations.
  • an inlet pipe 20 also opens into the enclosure 10 in order to admit air therefrom the outside atmosphere by means of two absolute filters 22 mounted in series.
  • the filters 22 can be of the same type as the filters 16 mounted in the outlet pipe 12.
  • a calibrated check valve 24 is also mounted in the inlet pipe 20, upstream of the filters 22, in order to regulate the flow of air entering the enclosure 10.
  • the assembly constituted by the inlet 20 and outlet 12 pipes and by the various devices mounted in these pipes constitutes a ventilation and filtration circuit ensuring in normal operation the establishment of a given vacuum inside the enclosure 10 and the regular ventilation of this enclosure.
  • the arrows 26 show in the figure the flow of air generated by this circuit in normal operation.
  • line 20 is provided in accordance with the present invention, to use line 20 as an outlet line or d suction and the outlet pipe 12 as the inlet pipe for emergency operation.
  • a second fan. suction 28 is mounted in the pipe 20, upstream of the valve 24 during normal operation of the circuit.
  • the use of the suction fan 28 controls, via the line 20, the maintenance of a vacuum at the inside the enclosure 10, and the air contained in the enclosure is regularly renewed by the pipe 12 as well as by a possible leak from the wall of the enclosure.
  • the direction of air flow is represented by the arrows 46 in the figure.
  • the suction fan 28 Since the suction fan 28 must make it possible to maintain a vacuum in the enclosure 10, even in the event of the sealing of the latter being broken, the power of this fan is greater than the power of the fan 14 ensuring the creation of depression in normal operation.
  • the power of the fan motor 28 is 85 Watts while the power of the fan motor 14 is 40 Watts.
  • the operation of the fan motor 28 is automatically controlled by the drop in vacuum prevailing inside the enclosure 10, whatever the cause of this drop in pressure.
  • a pressure switch 30 communicates with the enclosure 10 by a pipe 32 in which are further arranged an absolute filter 34 and a full-flow valve 36.
  • the filter 34 is of the same type as the filters 16 and 22 and protects the pressure switch 30 from any contamination, while the valve 36 makes it possible to isolate the latter from the enclosure when necessary, and in particular during sterilizations.
  • the pressure switch 30 In the event of a fall in the vacuum prevailing in the enclosure 10, the pressure switch 30 emits a signal which is transmitted by an electrical circuit 38 to an electronic control system of conventional design 40 which in turn delivers a control signal transmitted by a line 42 to the fan motor 28.
  • the start-up of the fan 28 is automatically controlled in order to restore the vacuum and circulation air in the direction of the arrows 46 inside the enclosure.
  • a sterilizer 44 can be connected to the inlet pipe 20 upstream of the valve 24.
  • the invention is not limited to the embodiment which has just been described by way of example but covers all the varian your.
  • the medium contained inside the enclosure can be different from atmospheric air.
  • the inlet and, optionally, outlet pipes are then connected to suitable conventional supply and outlet circuits.

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Combustion & Propulsion (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Filtering Of Dispersed Particles In Gases (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Ventilation (AREA)
  • Accommodation For Nursing Or Treatment Tables (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP81400177A 1980-02-12 1981-02-04 Kreislauf zum Belüften und Filtern der Atmosphäre in einem abgedichteten Raum Expired EP0034096B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8003067A FR2475679A1 (fr) 1980-02-12 1980-02-12 Circuit de ventilation et de filtration du milieu contenu dans une enceinte etanche
FR8003067 1980-02-12

Publications (2)

Publication Number Publication Date
EP0034096A1 true EP0034096A1 (de) 1981-08-19
EP0034096B1 EP0034096B1 (de) 1983-12-21

Family

ID=9238496

Family Applications (1)

Application Number Title Priority Date Filing Date
EP81400177A Expired EP0034096B1 (de) 1980-02-12 1981-02-04 Kreislauf zum Belüften und Filtern der Atmosphäre in einem abgedichteten Raum

Country Status (5)

Country Link
US (1) US4435194A (de)
EP (1) EP0034096B1 (de)
JP (1) JPS56130547A (de)
DE (1) DE3161670D1 (de)
FR (1) FR2475679A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2522791A1 (fr) * 1982-03-05 1983-09-09 Loubet Eliane Equipement de controle pour pressuriseurs conditionneurs d'air notamment pour cabines de travail en atmosphere polluee
FR2617264A1 (fr) * 1987-06-25 1988-12-30 Commissariat Energie Atomique Soupape de securite a pleine ouverture pour une enceinte en depression
EP0326257A1 (de) * 1988-01-29 1989-08-02 United Kingdom Atomic Energy Authority Strömungsgerät

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2522963A1 (fr) * 1982-03-12 1983-09-16 Calhene Installation pour le confinement et le transport en atmosphere sterile d'etres humains, notamment de nouveau-nes
US4584930A (en) * 1982-04-06 1986-04-29 British Nuclear Fuels Limited Ventilation systems for glove boxes
JPS6111051A (ja) * 1984-06-27 1986-01-18 ハウス食品工業株式会社 無菌空気製造装置
FR2574520B1 (fr) * 1984-12-11 1987-07-10 Cogema Dispositif de ventilation d'une enceinte confinee
US4894207A (en) * 1986-10-03 1990-01-16 Archer Aire Industries, Inc. Recirculating high velocity hot air sterilizing device
US4824644A (en) * 1987-04-30 1989-04-25 Archeraire Industries, Inc. Recirculating high velocity hot air sterilizing device having improved internal insulation structure
US4909999A (en) * 1987-07-06 1990-03-20 American Sterilizer Company Flow-through vapor phase sterilization system
US4937046A (en) * 1988-01-26 1990-06-26 H. W. Andersen Products Inc. Sterilization system and method
US4954315A (en) * 1988-02-03 1990-09-04 Mg Industries Method for recovery of sterilizing gas
US5188800A (en) * 1988-06-03 1993-02-23 Implant Innovations, Inc. Dental implant system
US5173258A (en) * 1989-10-11 1992-12-22 American Sterilizer Company Recirculation, vapor and humidity control in a sealable enclosure
JP4153029B2 (ja) * 1992-03-13 2008-09-17 アメリカン ステリライザー カンパニー 多数の成分を含有する滅菌剤のための滅菌装置および方法
DK85093D0 (da) * 1993-07-16 1993-07-16 Landsforeningen Til Kraeftens Method and apparatus for performing operations
US5368633A (en) * 1993-08-12 1994-11-29 Morrison-Knudson (An Idaho Corporation) Pressurized radioactive gas treatment system
US5906794A (en) * 1995-06-15 1999-05-25 American Sterilizer Company Continuous-operation, closed loop decontamination system and method
US5738713A (en) * 1995-08-10 1998-04-14 Firth; Jay A. Apparatus for biological control of noxious gas from swine waste
US5965087A (en) * 1996-02-27 1999-10-12 The Boc Group, Inc. System and method for controlling microorganisms associated with poultry
US5795552A (en) * 1996-03-04 1998-08-18 Eastman Kodak Company Apparatus for heating and venting a container
US5876664A (en) * 1996-06-14 1999-03-02 American Sterilizer Company Continuous-operation, closed loop decontamination system and method
US5865144A (en) * 1997-08-29 1999-02-02 Semenuk; Michael Ventilated cage for laboratory animal
US6257171B1 (en) 1998-01-16 2001-07-10 Animal Care Systems, Inc. Animal caging and biological storage systems
US6387156B1 (en) * 2000-05-15 2002-05-14 Agfa Corporation Filtration system for collecting and filtering particles and fumes from ablative imaging plates
ATE377942T1 (de) * 2001-09-26 2007-11-15 Ovagen Internat Ltd Verfahren zur herstellung von vogeleiern und vögeln die frei sind von einer bestimmten kontamination
WO2003104087A2 (en) * 2001-11-08 2003-12-18 United States Postal Service Handling potentially contaminated mail
JP2003286012A (ja) * 2002-03-28 2003-10-07 Toshiba Corp ガスリサイクルシステムおよび方法、ガス絶縁機器、六弗化硫黄供給システム並びに電力事業システム
US7027887B2 (en) * 2002-07-03 2006-04-11 Theries, Llc Apparatus, systems and methods for use in three-dimensional printing
US6911061B2 (en) * 2002-09-05 2005-06-28 Nuclear Filter Technology In-line HEPA filter
GB2393393B (en) * 2002-09-24 2005-06-15 Bioquell Uk Ltd A pre-sterilisation ante-chamber for a processing enclosure
US6835233B2 (en) * 2003-02-20 2004-12-28 Taiwan Semiconductor Manufacturing Co., Ltd Method and apparatus for reducing particle contamination
DE602004026646D1 (de) * 2004-08-18 2010-05-27 Lg Electronics Inc Kontrollverfahren zum automatischen trocknen
CN2851928Y (zh) * 2005-12-05 2006-12-27 丁祺恒 空气净化过滤系统
WO2014018265A2 (en) 2012-07-23 2014-01-30 Lenderking Caging Products Cage for laboratory animal
US9275767B2 (en) * 2013-02-06 2016-03-01 Westinghouse Electric Company Llc Systems and methods for generating power employing VES air supply stored energy
CN103234244B (zh) * 2013-04-28 2015-09-30 姜天华 层流动态空气消毒机
CN111086029B (zh) * 2019-12-31 2021-10-08 深圳市华星光电半导体显示技术有限公司 手套箱系统

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US3396375A (en) * 1965-05-20 1968-08-06 Atomic Energy Commission Usa Fail-safe alarm system
FR2130721A1 (de) * 1971-03-26 1972-11-03 Grundy Equipment Ltd
FR2197611A2 (de) * 1972-09-01 1974-03-29 Draegerwerk Ag
DE2530608A1 (de) * 1975-07-09 1977-01-27 Kernforschung Gmbh Ges Fuer Sicherheitseinrichtung

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Publication number Priority date Publication date Assignee Title
US3396375A (en) * 1965-05-20 1968-08-06 Atomic Energy Commission Usa Fail-safe alarm system
FR2130721A1 (de) * 1971-03-26 1972-11-03 Grundy Equipment Ltd
FR2197611A2 (de) * 1972-09-01 1974-03-29 Draegerwerk Ag
DE2530608A1 (de) * 1975-07-09 1977-01-27 Kernforschung Gmbh Ges Fuer Sicherheitseinrichtung

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2522791A1 (fr) * 1982-03-05 1983-09-09 Loubet Eliane Equipement de controle pour pressuriseurs conditionneurs d'air notamment pour cabines de travail en atmosphere polluee
EP0092448A1 (de) * 1982-03-05 1983-10-26 Société SODICEP (S.a.r.l.) Überdruck-Klimaanlage, insbesondere für Arbeitskabinen in verunreinigter Umgebungsluft
FR2617264A1 (fr) * 1987-06-25 1988-12-30 Commissariat Energie Atomique Soupape de securite a pleine ouverture pour une enceinte en depression
EP0297954A1 (de) * 1987-06-25 1989-01-04 Commissariat A L'energie Atomique Ein sich vollständig öffnendes Sicherheitsventil für ein Vakuumgehäuse
EP0326257A1 (de) * 1988-01-29 1989-08-02 United Kingdom Atomic Energy Authority Strömungsgerät

Also Published As

Publication number Publication date
FR2475679B1 (de) 1984-03-09
DE3161670D1 (en) 1984-01-26
US4435194A (en) 1984-03-06
JPS56130547A (en) 1981-10-13
FR2475679A1 (fr) 1981-08-14
EP0034096B1 (de) 1983-12-21

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