EP0070259A2 - Künstliche Herzklappe - Google Patents

Künstliche Herzklappe Download PDF

Info

Publication number
EP0070259A2
EP0070259A2 EP82830152A EP82830152A EP0070259A2 EP 0070259 A2 EP0070259 A2 EP 0070259A2 EP 82830152 A EP82830152 A EP 82830152A EP 82830152 A EP82830152 A EP 82830152A EP 0070259 A2 EP0070259 A2 EP 0070259A2
Authority
EP
European Patent Office
Prior art keywords
obturator
central axis
annular frame
frame
angular position
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP82830152A
Other languages
English (en)
French (fr)
Other versions
EP0070259B1 (de
EP0070259A3 (en
Inventor
Franco Vallana
Gioachino Bona
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sorin Biomedica Cardio SpA
Original Assignee
Sorin Biomedica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sorin Biomedica SpA filed Critical Sorin Biomedica SpA
Priority to AT82830152T priority Critical patent/ATE21617T1/de
Publication of EP0070259A2 publication Critical patent/EP0070259A2/de
Publication of EP0070259A3 publication Critical patent/EP0070259A3/en
Application granted granted Critical
Publication of EP0070259B1 publication Critical patent/EP0070259B1/de
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2403—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with pivoting rigid closure members
    • A61F2/2406—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with pivoting rigid closure members without fixed axis
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K15/00—Check valves
    • F16K15/02—Check valves with guided rigid valve members
    • F16K15/03—Check valves with guided rigid valve members with a hinged closure member or with a pivoted closure member
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/7722—Line condition change responsive valves
    • Y10T137/7837—Direct response valves [i.e., check valve type]
    • Y10T137/7898—Pivoted valves
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/7722—Line condition change responsive valves
    • Y10T137/7837—Direct response valves [i.e., check valve type]
    • Y10T137/7898—Pivoted valves
    • Y10T137/7903—Weight biased

Definitions

  • the present invention relates to heart valve prostheses, and is particularly concerned with a prosthesis comprising an annular frame, a disc-shaped obturator, and means for coupling the obturator to the annular frame which enable the obturator to rotate about its central axis and to orient itself about one of its chordal axes, under the action of the blood flow, between an open angular position and a closed angular position, so as to allow the flow of blood through the aperture of the annular frame in one direction and the interruption of the flow in the opposite direction, respectively.
  • prosthetic heart valves of the aforesaid type there is the problem of reproducing the fluid dynamic characteristics of natural heart valves, which are marked by a very low pressure gradient and the absence of areas of turbulent flow, vortices or stasis in the blood flow.
  • the pressure gradient across the prosthetic valve is directly related to heart activity, while irregularities of the blood flow through the prosthesis may cause haemolysis, thrombosis and changes in the characteristics of the blood medium.
  • the obturator is in the form of a substantially flat disc which is coupled to the annular frame in such a manner that, when in the open angular position, it normally forms an angle of between 60° and 80° with the plane of the frame.
  • the pressure exerted by the blood flow on the side of the disc which is opposite the central axis of the annular frame -causes the obturator to return to the closed position, in which the obturator interrupts the flow of blood through the prosthesis.
  • the obturator acts as a deflector of the blood flow and encourages the formation of turbulence and vortices, particularly around its peripheral parts which serve respectively as an inlet edge and an outlet edge of the obturator in the blood flow.
  • the object of the present invention is to provide a heart valve prosthesis of the type specified above without the above-mentioned drawbacks.
  • the present invention relates to a heart valve prosthesis of the type specified above, characterised in that the coupling ; means are such as to enable the obturator to orient itself substantially perpendicular to the plane of the frame in the open position, and in that the side of the obturator which faces away from the central axis of the annular frame in the open angular position is defined, ) at least in its peripheral part, by a surface which is generated by rotation, about the central axis of the obturator, of a curve the locus of the centres of curvature of which lies on the opposite side of said curve from a curve which generates, by rotation about said central axis,a surface defining the other side of the obturator.
  • the peripheral part of the obturator lies in a plane which is substantially parallel to the lines of the blood flow through the central aperture of the frame. The formation of any turbulence, vortices or other irregularities in the blood flow is thus avoided.
  • Figure 1 shows, in its entirety, an annular frame 1 of biocompatible material with a central aperture la and with a central axis lb.
  • the outer surface of the annular frame 1 has a textile covering 2 made from a biocompatible synthetic yarn.
  • the covering 2 acts as a sutural element which enables the prosthesis to be applied to the heart muscle after removal of the original valve membranes.
  • a disc shaped obturator 3 which has rotational symmetry about a central axis 3a and is pivotable relative to the frame 1 between an open angular position, shown by the continuous line A in Figure 2, and a closed angular position, shown by the broken lines B in the same Figure.
  • the obturator 3 In the open angular position A, the obturator 3 allows blood to flow through the central aperture la of the annular frame 1 in the direction shown by the arrow in Figure 2.
  • the obturator 3 In the closed angular position B, the obturator 3 interrupts the flow of blood in the opposite direction through the aperture la.
  • the obturator 3 is coupled to the annular frame 1 with a slight radial clearance which allows the obturator 3 to rotate about its central axis 3a, in addition to the angular orienting movement between the open position A and the closed position B, so that the mechanical stresses and phenomena of wear which appear during the operation of the prosthesis are uniformly distributed around the edge of the obturator 3.
  • the obturator 3 is coupled to the annular frame 1 by coupling means, generally indicated 10, which allow the obturator 3 to orient itself angularly about an axis lying on a chord which is approximately equidistant from the central axis lb and the peripheral edge of the annular frame 1.
  • the orientation axis of the obturator 3 may be displaced during the angular movement between the open position A and the closed position B when, during this movement, the obturator 3 effects a slight translational movement in its own plane.
  • this axis will be defined as the "chordal axis" in the claim which follows.
  • the coupling means 10 comprise a pair of first protuberances lOa and a pair of second protuberances 10b, which project from the frame 1 into the aperture la, and triangular projections 10c which extend from the annular frame 1 in an approximately axial direction relative to the frame 1.
  • the first protuberances 10a engage a side 3b of the obturator 3, which faces towards the central axis lb of the frame 1 in the open position A.
  • the second protuberances 10b engage the other side 3c of the obturator 3, which faces away from the central axis lb in the open position A.
  • each first protuberance 10a forms, with the respective second protuberance lOb, a fork-shaped element which embraces a peripheral part of the obturator 3 and, in the manner of a fulcrum, guides the orienting movement of the obturator 3 relative to the frame 1.
  • the triangular projections 10c are curved slightly towards the inside of the annular frame 1, and those of their faces which are turned towards the central axis lb of the frame 1 have a concavity complementary to the peripheral curvature of the obturator 3, so that the obturator 3 is retained by the annular frame 1, being coupled thereto in a manner which permits the orientation.
  • the triangular projections 10c have edges 10d which face the central axis lb and are curved slightly towards the inside of the annular frame 1.
  • the curved edges 10d curtail the opening stroke of the obturator 3 at position A where the obturator 3 is substantially perpendicular to the plane of the annular frame 1.
  • the side 3c of the obturator 3 is defined, in its central part, by a convex surface and, in its peripheral part, by a surface which is generated by rotation, about the central axis 3a of the obturator, of a curve the locus of the centres of curvature of which lies on the opposite side of this curve from a curve (straight in the example shown in Figures 1 and 2) which generates, by rotation around the central axis 3a, a surface defining the other side 3b of obturator 3.
  • the two generatrix curves must be mutually positioned in a plane which is radial to the obturator (the plane of rotation).
  • the side 13c of the obturator 3 which faces away from the central axis lb of the annular frame 1 in the open angular position A is defined entirely by a rotation surface of the aforesaid type.
  • the obturator shown in Figure 3 differs from that shown in Figures 1 and 2 only in that the central part of the side 13c in Figure 3 has a more or less pointed convexity., in contrast to the rounded convexity characteristic of the central part of the side 3b of the obturator 3 shown in Figures 1 and 2.
  • the side 23c corresponding to sides 3c, 13c of Figures 1, 2 and 3 is defined by a conical surface where the locus of the centres of curvature lies virtually at infinity.
  • the surfaces defining the sides 3c, 13c, 23c of the obturator 3 are identical to the surfaces which define the corresponding sides of the obturators illustrated in Figures 2, 3 and 4 respectively.
  • the sides 13b, 23b, 33b which face the central axis lc of the annular frame 1 in the open position A are defined by surfaces which are complementary to the surfaces of the sides 3c, 13c and 23c respectively, thus giving the obturator a more or less constant thickness in all parts.
  • valve prosthesis which will now be described with reference to the embodiment shown in Figures 1 and 2, is controlled by the action of the blood flow on the obturator 3.
  • the obturator 3 When the obturator 3 is in the open angular position A and the blood is flowing through the central aperture of the annular frame 1 in the direction indicated diagrammatically by the arrow in Figure 2, the obturator 3 lies in a plane which is substantially perpendicular to the plane of the frame 1 and its central axis 3a is substantially perpendicular to the central axis 1b of frame 1.
  • the obturator 3 offers minimal resistance to the blood flow.
  • the peripheral edge of obturator 3 lies in a plane which is substantially parallel to the axis lb and the lines of blood flow. In this manner, the formation of turbulence, vortices and other irregularities in the blood flow is kept to a minimum.
  • the deviation of the flow lines caused by obturator 3 is gradual, and their parallelism is restored immediately downstream of the obturator.
  • the blood stream impinges on the side 3b of the obturator 3 which faces the aperture la in the closed position B, and the obturator 3 is thereby returned to its open position A.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Prostheses (AREA)
  • External Artificial Organs (AREA)
  • Materials For Medical Uses (AREA)
EP82830152A 1981-07-14 1982-06-01 Künstliche Herzklappe Expired EP0070259B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT82830152T ATE21617T1 (de) 1981-07-14 1982-06-01 Kuenstliche herzklappe.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT6797281 1981-07-14
IT67972/81A IT1144379B (it) 1981-07-14 1981-07-14 Protesi valvolare cardiaca

Publications (3)

Publication Number Publication Date
EP0070259A2 true EP0070259A2 (de) 1983-01-19
EP0070259A3 EP0070259A3 (en) 1983-11-30
EP0070259B1 EP0070259B1 (de) 1986-08-27

Family

ID=11306849

Family Applications (1)

Application Number Title Priority Date Filing Date
EP82830152A Expired EP0070259B1 (de) 1981-07-14 1982-06-01 Künstliche Herzklappe

Country Status (6)

Country Link
US (1) US4423525A (de)
EP (1) EP0070259B1 (de)
AT (1) ATE21617T1 (de)
DE (1) DE3272871D1 (de)
ES (1) ES513770A0 (de)
IT (1) IT1144379B (de)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4676789A (en) * 1985-05-16 1987-06-30 Sorensen H Rahbek Heart valve
EP0277527A1 (de) * 1987-01-22 1988-08-10 B. Braun Melsungen AG Herzklappenprothese
EP0277528A1 (de) * 1987-01-22 1988-08-10 B. Braun Melsungen AG Herzklappenprothese
EP0321588A4 (de) * 1987-06-25 1989-06-26 Bukatov Alexandr S Herzklappenprothese.
US5755783A (en) * 1996-07-29 1998-05-26 Stobie; Robert Suture rings for rotatable artificial heart valves
US8366769B2 (en) 2000-06-01 2013-02-05 Edwards Lifesciences Corporation Low-profile, pivotable heart valve sewing ring

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822353A (en) * 1984-09-24 1989-04-18 Carbomedics, Inc. Heart valve
US4872875A (en) * 1989-01-28 1989-10-10 Carbon Implants, Inc. Prosthetic heart valve
US5522886A (en) * 1994-07-29 1996-06-04 Milo; Simcha Heart valve prostheses
US8308797B2 (en) 2002-01-04 2012-11-13 Colibri Heart Valve, LLC Percutaneously implantable replacement heart valve device and method of making same
US8870950B2 (en) 2009-12-08 2014-10-28 Mitral Tech Ltd. Rotation-based anchoring of an implant
US8961596B2 (en) 2010-01-22 2015-02-24 4Tech Inc. Method and apparatus for tricuspid valve repair using tension
US10058323B2 (en) 2010-01-22 2018-08-28 4 Tech Inc. Tricuspid valve repair using tension
US9307980B2 (en) 2010-01-22 2016-04-12 4Tech Inc. Tricuspid valve repair using tension
US8475525B2 (en) 2010-01-22 2013-07-02 4Tech Inc. Tricuspid valve repair using tension
US20110224785A1 (en) 2010-03-10 2011-09-15 Hacohen Gil Prosthetic mitral valve with tissue anchors
WO2012006124A2 (en) 2010-06-28 2012-01-12 Vela Biosystems Llc Method and apparatus for the endoluminal delivery of intravascular devices
US9763657B2 (en) 2010-07-21 2017-09-19 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US9132009B2 (en) 2010-07-21 2015-09-15 Mitraltech Ltd. Guide wires with commissural anchors to advance a prosthetic valve
US11653910B2 (en) 2010-07-21 2023-05-23 Cardiovalve Ltd. Helical anchor implantation
JP2014507179A (ja) 2010-12-14 2014-03-27 コリブリ ハート バルブ エルエルシー 統合された弁尖を伴う折り畳まれた膜の心臓弁膜尖を含む経皮的にデリバリー可能な心臓弁
WO2012177942A2 (en) 2011-06-21 2012-12-27 Hanson Gifford, Iii Prosthetic heart valve devices and associated systems and methods
WO2013011502A2 (en) 2011-07-21 2013-01-24 4Tech Inc. Method and apparatus for tricuspid valve repair using tension
US8852272B2 (en) 2011-08-05 2014-10-07 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US20140324164A1 (en) 2011-08-05 2014-10-30 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
WO2013021374A2 (en) 2011-08-05 2013-02-14 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
WO2013021375A2 (en) 2011-08-05 2013-02-14 Mitraltech Ltd. Percutaneous mitral valve replacement and sealing
JP6133309B2 (ja) 2011-10-19 2017-05-24 トゥエルヴ， インコーポレイテッド 人工心臓弁デバイス
US9039757B2 (en) 2011-10-19 2015-05-26 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
CN103889369B (zh) 2011-10-19 2016-09-14 托尔福公司 用于心脏瓣膜置换术的装置
US11202704B2 (en) 2011-10-19 2021-12-21 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US8961594B2 (en) 2012-05-31 2015-02-24 4Tech Inc. Heart valve repair system
US8628571B1 (en) 2012-11-13 2014-01-14 Mitraltech Ltd. Percutaneously-deliverable mechanical valve
CN105007832B (zh) 2013-01-09 2018-01-23 4科技有限公司 组织锚状物设备
US20150351906A1 (en) 2013-01-24 2015-12-10 Mitraltech Ltd. Ventricularly-anchored prosthetic valves
WO2014141239A1 (en) 2013-03-14 2014-09-18 4Tech Inc. Stent with tether interface
EP3062709A2 (de) 2013-10-30 2016-09-07 4Tech Inc. Spannungssystem mit mehreren verankerungspunkten
US10022114B2 (en) 2013-10-30 2018-07-17 4Tech Inc. Percutaneous tether locking
US10052095B2 (en) 2013-10-30 2018-08-21 4Tech Inc. Multiple anchoring-point tension system
EP3157607B1 (de) 2014-06-19 2019-08-07 4Tech Inc. Herzgewebe-cinch
WO2016016899A1 (en) 2014-07-30 2016-02-04 Mitraltech Ltd. Articulatable prosthetic valve
US9907547B2 (en) 2014-12-02 2018-03-06 4Tech Inc. Off-center tissue anchors
CA2973940C (en) 2015-02-05 2022-08-23 Mitraltech Ltd. Prosthetic valve with axially-sliding frames
US9974651B2 (en) 2015-02-05 2018-05-22 Mitral Tech Ltd. Prosthetic valve with axially-sliding frames
US10531866B2 (en) 2016-02-16 2020-01-14 Cardiovalve Ltd. Techniques for providing a replacement valve and transseptal communication
GB201613219D0 (en) 2016-08-01 2016-09-14 Mitraltech Ltd Minimally-invasive delivery systems
USD800908S1 (en) 2016-08-10 2017-10-24 Mitraltech Ltd. Prosthetic valve element
WO2018029680A1 (en) 2016-08-10 2018-02-15 Mitraltech Ltd. Prosthetic valve with concentric frames
US10702378B2 (en) 2017-04-18 2020-07-07 Twelve, Inc. Prosthetic heart valve device and associated systems and methods
US10709591B2 (en) 2017-06-06 2020-07-14 Twelve, Inc. Crimping device and method for loading stents and prosthetic heart valves
US10729541B2 (en) 2017-07-06 2020-08-04 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
US10786352B2 (en) 2017-07-06 2020-09-29 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
US10537426B2 (en) 2017-08-03 2020-01-21 Cardiovalve Ltd. Prosthetic heart valve
US10888421B2 (en) 2017-09-19 2021-01-12 Cardiovalve Ltd. Prosthetic heart valve with pouch
US12064347B2 (en) 2017-08-03 2024-08-20 Cardiovalve Ltd. Prosthetic heart valve
US10575948B2 (en) 2017-08-03 2020-03-03 Cardiovalve Ltd. Prosthetic heart valve
US11793633B2 (en) 2017-08-03 2023-10-24 Cardiovalve Ltd. Prosthetic heart valve
US11246704B2 (en) 2017-08-03 2022-02-15 Cardiovalve Ltd. Prosthetic heart valve
US11395726B2 (en) 2017-09-11 2022-07-26 Incubar Llc Conduit vascular implant sealing device for reducing endoleaks
US12458493B2 (en) 2017-09-19 2025-11-04 Cardiovalve Ltd. Prosthetic heart valve and delivery systems and methods
US9895226B1 (en) 2017-10-19 2018-02-20 Mitral Tech Ltd. Techniques for use with prosthetic valve leaflets
WO2019079788A1 (en) 2017-10-20 2019-04-25 Boston Scientific Scimed, Inc. CARDIAC VALVE REPAIR IMPLANT FOR THE TREATMENT OF TRICUSPID REGURGITATION
GB201720803D0 (en) 2017-12-13 2018-01-24 Mitraltech Ltd Prosthetic Valve and delivery tool therefor
GB201800399D0 (en) 2018-01-10 2018-02-21 Mitraltech Ltd Temperature-control during crimping of an implant
US12186188B2 (en) 2019-05-01 2025-01-07 Twelve, Inc. Support devices for transcatheter delivery system handles
US11452599B2 (en) 2019-05-02 2022-09-27 Twelve, Inc. Fluid diversion devices for hydraulic delivery systems and associated methods
US11857417B2 (en) 2020-08-16 2024-01-02 Trilio Medical Ltd. Leaflet support
US12357459B2 (en) 2020-12-03 2025-07-15 Cardiovalve Ltd. Transluminal delivery system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3476143A (en) 1967-04-17 1969-11-04 Univ Minnesota Pivoting disc heart valve
AU450689B2 (en) * 1969-06-10 1974-07-02 Regents Ofthe Universityof Minnesota Pivoting disc heart valve
US4240161A (en) 1979-02-21 1980-12-23 Medical, Incorporated Arcuate disc heart valve
US4308624A (en) 1979-08-07 1982-01-05 Hemex, Inc. Heart valve prosthesis

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4676789A (en) * 1985-05-16 1987-06-30 Sorensen H Rahbek Heart valve
EP0277527A1 (de) * 1987-01-22 1988-08-10 B. Braun Melsungen AG Herzklappenprothese
EP0277528A1 (de) * 1987-01-22 1988-08-10 B. Braun Melsungen AG Herzklappenprothese
EP0321588A4 (de) * 1987-06-25 1989-06-26 Bukatov Alexandr S Herzklappenprothese.
US5755783A (en) * 1996-07-29 1998-05-26 Stobie; Robert Suture rings for rotatable artificial heart valves
US6143025A (en) * 1996-07-29 2000-11-07 Edwards Lifesciences Corporation Suture rings for rotatable artificial heart valves
US8366769B2 (en) 2000-06-01 2013-02-05 Edwards Lifesciences Corporation Low-profile, pivotable heart valve sewing ring

Also Published As

Publication number Publication date
ES8303914A1 (es) 1983-03-01
IT8167972A0 (it) 1981-07-14
EP0070259B1 (de) 1986-08-27
EP0070259A3 (en) 1983-11-30
DE3272871D1 (en) 1986-10-02
US4423525A (en) 1984-01-03
IT1144379B (it) 1986-10-29
ATE21617T1 (de) 1986-09-15
ES513770A0 (es) 1983-03-01

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