EP0084086A2 - Microsonde à laser - Google Patents

Microsonde à laser Download PDF

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Publication number
EP0084086A2
EP0084086A2 EP82109634A EP82109634A EP0084086A2 EP 0084086 A2 EP0084086 A2 EP 0084086A2 EP 82109634 A EP82109634 A EP 82109634A EP 82109634 A EP82109634 A EP 82109634A EP 0084086 A2 EP0084086 A2 EP 0084086A2
Authority
EP
European Patent Office
Prior art keywords
laser
time
sample
ion
excitation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP82109634A
Other languages
German (de)
English (en)
Other versions
EP0084086A3 (fr
Inventor
Hans-Josef Dr. Heinen
Stefan Meier
Henning Vogt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Balzers und Leybold Deutschland Holding AG
Original Assignee
Leybold Heraeus GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leybold Heraeus GmbH filed Critical Leybold Heraeus GmbH
Publication of EP0084086A2 publication Critical patent/EP0084086A2/fr
Publication of EP0084086A3 publication Critical patent/EP0084086A3/fr
Withdrawn legal-status Critical Current

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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Definitions

  • Laser microprobes of this type have been known for a long time (cf. Nature, Vol. 256, July 10, 1975) and have been on the market.

Landscapes

  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
EP82109634A 1982-01-16 1982-10-19 Microsonde à laser Withdrawn EP0084086A3 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3201264 1982-01-16
DE19823201264 DE3201264A1 (de) 1982-01-16 1982-01-16 Lasermikrosonde

Publications (2)

Publication Number Publication Date
EP0084086A2 true EP0084086A2 (fr) 1983-07-27
EP0084086A3 EP0084086A3 (fr) 1984-02-22

Family

ID=6153253

Family Applications (1)

Application Number Title Priority Date Filing Date
EP82109634A Withdrawn EP0084086A3 (fr) 1982-01-16 1982-10-19 Microsonde à laser

Country Status (2)

Country Link
EP (1) EP0084086A3 (fr)
DE (1) DE3201264A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0539664A1 (fr) * 1991-10-28 1993-05-05 SPECTRO ANALYTICAL INSTRUMENTS Gesellschaft für analytische Messgeräte mbH Système programmable de commande et d'enregistrement des données pour un spectromètre de masse à temps de vol
US5894063A (en) * 1993-05-28 1999-04-13 Baylor College Of Medicine Surface-enhanced neat desorption for disorption and detection of analytes
US6020208A (en) * 1994-05-27 2000-02-01 Baylor College Of Medicine Systems for surface-enhanced affinity capture for desorption and detection of analytes
US7294515B2 (en) 1993-05-28 2007-11-13 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
US20210391161A1 (en) * 2019-01-15 2021-12-16 Fluidigm Canada Inc. Direct ionization in imaging mass spectrometry operation

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641959A (en) * 1995-12-21 1997-06-24 Bruker-Franzen Analytik Gmbh Method for improved mass resolution with a TOF-LD source

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3307033A (en) * 1963-07-19 1967-02-28 William H Johnston Lab Inc Coincidence mass spectrometer with electrostatic means to separate positive and negative ions and detectors and method of use
FR1580234A (fr) * 1968-05-15 1969-09-05

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0539664A1 (fr) * 1991-10-28 1993-05-05 SPECTRO ANALYTICAL INSTRUMENTS Gesellschaft für analytische Messgeräte mbH Système programmable de commande et d'enregistrement des données pour un spectromètre de masse à temps de vol
US6734022B2 (en) 1993-05-28 2004-05-11 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
US6027942A (en) * 1993-05-28 2000-02-22 Baylor College Medicine Surface-enhanced affinity capture for desorption and detection or analytes
US6124137A (en) * 1993-05-28 2000-09-26 Baylor College Of Medicine Surface-enhanced photolabile attachment and release for desorption and detection of analytes
US6528320B2 (en) 1993-05-28 2003-03-04 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
US5894063A (en) * 1993-05-28 1999-04-13 Baylor College Of Medicine Surface-enhanced neat desorption for disorption and detection of analytes
US7071003B2 (en) 1993-05-28 2006-07-04 Baylor College Of Medicine Surface-enhanced laser desorption/Ionization for desorption and detection of analytes
US7294515B2 (en) 1993-05-28 2007-11-13 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
US7413909B2 (en) * 1993-05-28 2008-08-19 Baylor College Of Medicine Method and apparatus for desorption and ionization of analytes
US7449150B2 (en) 1993-05-28 2008-11-11 Baylor College Of Medicine Probe and apparatus for desorption and ionization of analytes
US7491549B2 (en) 1993-05-28 2009-02-17 Baylor College Of Medicine Apparatus for desorption and ionization of analytes
US8748193B2 (en) 1993-05-28 2014-06-10 Baylor College Of Medicine Apparatus for desorption and ionization of analytes
US6020208A (en) * 1994-05-27 2000-02-01 Baylor College Of Medicine Systems for surface-enhanced affinity capture for desorption and detection of analytes
US20210391161A1 (en) * 2019-01-15 2021-12-16 Fluidigm Canada Inc. Direct ionization in imaging mass spectrometry operation

Also Published As

Publication number Publication date
DE3201264A1 (de) 1983-07-28
EP0084086A3 (fr) 1984-02-22

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19821019

AK Designated contracting states

Designated state(s): DE FR GB NL

PUAL Search report despatched

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AK Designated contracting states

Designated state(s): DE FR GB NL

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19850531

RIN1 Information on inventor provided before grant (corrected)

Inventor name: HEINEN, HANS-JOSEF, DR.

Inventor name: VOGT, HENNING

Inventor name: MEIER, STEFAN