EP0143796B1 - Dosierpipette - Google Patents

Dosierpipette Download PDF

Info

Publication number
EP0143796B1
EP0143796B1 EP84901351A EP84901351A EP0143796B1 EP 0143796 B1 EP0143796 B1 EP 0143796B1 EP 84901351 A EP84901351 A EP 84901351A EP 84901351 A EP84901351 A EP 84901351A EP 0143796 B1 EP0143796 B1 EP 0143796B1
Authority
EP
European Patent Office
Prior art keywords
dosage
rack
toothed
lever
toothing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
EP84901351A
Other languages
English (en)
French (fr)
Other versions
EP0143796A1 (de
Inventor
Mikael Fagerstedt
Erkki Kaski
Jukka TERVAMÄKI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Fisher Scientific Oy
Original Assignee
Labsystems Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labsystems Oy filed Critical Labsystems Oy
Priority to AT84901351T priority Critical patent/ATE31150T1/de
Publication of EP0143796A1 publication Critical patent/EP0143796A1/de
Application granted granted Critical
Publication of EP0143796B1 publication Critical patent/EP0143796B1/de
Expired legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0234—Repeating pipettes, i.e. for dispensing multiple doses from a single charge

Definitions

  • the invention described herein is concerned with a pipette which is provided with a piston and a cylinder and with two operating knobs, whereat, by means of one of the said knobs, the cylinder can be filled with liquid by depressing the knob once, and by means of the other one of the knobs, the cylinder can be emptied stepwise by means of successive depressions of the piston, of desired magnitude.
  • a pipette which is provided with a piston and a cylinder and with two operating knobs, whereat, by means of one of the said knobs, the cylinder can be filled with liquid by depressing the knob once, and by means of the other one of the knobs, the cylinder can be emptied stepwise by means of successive depressions of the piston, of desired magnitude.
  • the said prior-art pipettes often involve the drawback that the filling lever must be operated by lifting, whereby two hands are usually required.
  • an error is often produced when, by mistake, the last dose is also dosed, in which case the piston can no longer be displaced over a sufficiently long distance.
  • the pipette of DE-A-2926691 has a special device to prevent actuation of the piston when insufficient liquid remains.
  • DE-A-3008346 discloses a dosage pipette has been piston mounted inside a cylinder.
  • a toothed dosage rack is attached to the piston and a striking pin is engageable with the dosage toothing of the toothed dosage rack.
  • the striking pin has coupled to it a dosage button so that when the dosage button is depressed the striking pin engages and displaces the toothed rack longitudinally.
  • the toothed dosage rack is also provided with a second toothing engaged by a cog wheel. That cog wheel engages a second toothed rack which is provided with a filling pressing knob.
  • a dosage pipette provided with a handle, a cylinder attached to the handle, a piston inside the cylinder, a toothed dosage rack attached to the piston, a striking pin engageable with the dosage toothing of the said rack, the said striking pin being mounted on a dosage lever so that, when the dosage lever is depressed, the striking pin engages and displaces the toothed rack longitudinally, characterised in that, at the side of the dosage toothing, there is pivoted lifting lever, whose pivot position in relation to the toothed rack can be adjusted longitudinally as desired by means of an adjusting device and which lever is provided at the end opposite its pivot with a cam disposed to lie laterally alongside the rack teeth, and which engages the striking pin to displace it from the dosage toothing during upward movement of the striking pin and disengages thereafter, and that the toothed dosage rack is additionally provided with a second toothing, with a cogwheel resting -against the said toothing and, at the opposite side, resting against
  • the pipette is easy to operate, because it can be filled by one hand, while the other hand remains free, e.g., for the handling of test tubes.
  • the lifting-lever system described here is of simple construction and reliable in operation. By means of the cam provided at the top end of the toothed rack, it is, moreover, possible to avoid the pipetting of the last, too little dose.
  • Figure 1 is a sectional side view of an embodiment
  • Figure 2 is a certain sectional view of same as viewed from the top
  • Figure 3 shows a detail of the tip portion of a multi-tip pipette.
  • the pipette comprises an oblong handle (1), at whose lower end there is a cylinder (2), and in the cylinder a piston (3).
  • the cylinder may be attached to the handle, e.g., by means of a bayonet socket.
  • a toothed rack (4) - parallel to the handle is attached, which rack is provided with two toothings (5) and (6).
  • a striking pin (8) is pressed against the toothing (6) by the force of a spring (16), and the striking pin is mounted on a lever (9).
  • the lever (9) is mounted on a shaft (15) located in the handle.
  • the lever is connected with a spring (19), which attempts to keep the lever in its upper position. The movement of the striking pin (8) is stopped at the lower position by a limiter (18)
  • a cogwheel 7 operates in contact with the toothing 5 on the toothed rack 4, which cogwheel is mounted on a shaft 10. At the other side, the cogwheel 7 operates in contact with a toothed rack 11, whose top end is provided with a press knob 12.
  • a resilient lifting lever 20 At the side of the toothing 6 on the toothed rack 4, there is a resilient lifting lever 20 and, on the lever, a cam 21, which raises the striking pin 8 apart from the toothing 6 during the stage of upward movement of the lever 9.
  • the top end of the lifting lever is provided with a guide pin 23, which is fitted into a guide groove 25 provided in the adjusting wheel 24.
  • the adjusting wheel is mounted on a shaft 26.
  • the top end of the toothed rack 4 is additionally provided with a cam 22, which, as the toothed rack approaches its lower position, shifts the lifting lever 20 towards the striking pin 8.
  • the pipette operates so that, when the lever 9 is in its upper position and when the striking pin 8 is, consequently, apart from the toothing 6 and when the piston 3 is in the cylinder 2 in its lower position, the press knob 12 is depressed, whereat the cogwheel 7 starts revolving and lifts the toothed rack 4 and, along with the rack, the piston 3 in the cylinder 2 upwards. In this way, suction is generated in the cylinder 2, whereby the cylinder is filled with liquid 13.
  • the dosage can be started by means of the lever 9.
  • the spring 16 presses the striking pin 8 into the toothing 6, whereat the striking pin 8 starts pushing the toothed rack 4 and the piston 3 downwards until the striking pin 8 meets the limiter 18, against which the movement stops.
  • the spring 19 restores the dosage lever 9 back to its upper position upon completion of the depressing.
  • the striking pin 8 must jump over the toothing 6 until; near the upper position of the striking pin 8, the cam 21 of the resilient lifting lever 20 raises the striking pin 8 apart from the toothing 6.
  • the dosage can be repeated until the toothed rack 4 and the piston 3 approach their lower position.
  • the cam 22 at the top end of the toothed rack 4 meets the lifting lever 20 and raises it by the height of the toothing 6.
  • the cam 21 of the lifting lever 20 raises the striking pin 8 to such an extent that the striking pin no longer reaches the toothing 6 when the lever 9 is depressed again for dosage.
  • the guide groove 25 shifts the lifting lever 20 upwards or downwards by the intermediate of the pin 23, whereat, correspondingly, at the botton end of the lifting lever, the cam 21 is shifted and permits the striking pin 8 to move over the desired distance on the toothing 6, e.g. over 1, 2, 3, 4 or more teeth, per each depression of the dosage lever 9. In this way, a 1-, 2-, 3- or 4-fold dose is obtained.
  • toothings 5 and 6 are shown as located one after the other, but, if desired, they may also be very well placed side by side on the toothed rack 4.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Transmission Devices (AREA)
  • Portable Nailing Machines And Staplers (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (5)

1. Dosierpipette mit einem Griff (1), einem am Griff befestigten Zylinder (2), einem Kolben (3) innerhalb des Zylinders, einer mit dem Kolben verbundenen Dosierzahnstange (4), einem mit der Dosierzahnung (6) der Zahnstange in Eingriff bringbaren Anschlagzapfen (8), wobei der Anschlagzapfen so auf einem Dosierhebel (9) angeordnet ist, daß, wenn der Dosierhebel gedrückt wird, der Anschlagzapfen mit der Zahnstange in Eingriff tritt und sie in Längsrichtung verschiebt, dadurch gekennzeichnet, daß auf der Seite der Dosierverzahnung ein Hubhebel (20) angelenkt ist, dessen Schwenklage mit Bezug zur Verzahnungsstange je nach Wunsch in Längsrichtung eingestellt werden kann, und zwar mittels einer Einstelleinrichtung (24), wobei der Hebel an seinem'der Anlenkung gegenüberliegenden Ende mit einem Nocken (21) versehen ist, der seitlich entlang der Zähne der Zahnstange liegt und der mit dem Anschlagzapfen in Eingriff tritt, um diesen von der Dosierverzahnung während der Aufwärtsbewegung des Anschlagzapfens (8) zu verschieben und dann zu lösen, und daß die Dosierzahnstange zusätzlich mit einer zweiten Verzahnung (5) versehen ist, wobei ein Sperrad (7) auf der Verzahnung aufruht und auf der gegenüberliegenden Seite an einer zweiten Zahnstange (11) anliegt, die mit einem Fülldruckknopf (12) versehen ist.
2. Pipette nach Anspruch 1, dadurch gekennzeichnet, daß die Dosierzahnstange am oberen Ende mit einem Nocken (22) versehen ist, der, wenn die Dosierzahnstange sich ihrer unteren Lage nähert, den Hubhebel gegen den Anschlagzapfen drückt, so daß der Hubhebel den Anschlagzapfen daran hindert, mit der Verzahnung in Kontakt zu treten.
3. Pipette nach Anspruch 1 oder 2, dadurch gekennzeichnet, daß die Verzahnungen auf der Dosierzahnstange nebeneinander angeordnet sind.
4. Pipette nach Anspruch 1 oder 2, dadurch gekennzeichnet, daß die Verzahnungen der Dosierzahnstange hintereinander angeordnet sind.
5. Pipette nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, daß der Fülldruckknopf seitlich an Griff angeordnet ist.
EP84901351A 1983-04-13 1984-03-29 Dosierpipette Expired EP0143796B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT84901351T ATE31150T1 (de) 1983-04-13 1984-03-29 Dosierpipette.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI831239A FI831239A0 (fi) 1983-04-13 1983-04-13 Doseringspipett
FI831239 1983-04-13

Publications (2)

Publication Number Publication Date
EP0143796A1 EP0143796A1 (de) 1985-06-12
EP0143796B1 true EP0143796B1 (de) 1987-12-02

Family

ID=8517044

Family Applications (1)

Application Number Title Priority Date Filing Date
EP84901351A Expired EP0143796B1 (de) 1983-04-13 1984-03-29 Dosierpipette

Country Status (7)

Country Link
EP (1) EP0143796B1 (de)
JP (1) JPS60501048A (de)
DE (1) DE3467860D1 (de)
FI (1) FI831239A0 (de)
IT (1) IT1178875B (de)
SU (1) SU1373300A3 (de)
WO (1) WO1984004056A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202010010942U1 (de) 2010-08-03 2011-11-08 Brand Gmbh + Co Kg Pipette für ein Pipettensystem mit Pipette und Spritze
EP4406655A3 (de) * 2020-06-22 2024-08-21 Eppendorf SE Pipette für den gebrauch mit einer einen kolben und einen zylinder aufweisenden pipettenspitze oder spritze

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728501A (en) * 1984-07-27 1988-03-01 Minoru Atake Adjustable liquid sampling apparatus
US4929428A (en) * 1988-02-19 1990-05-29 Fuji Photo Film Co., Ltd. Quantitative pipette
DE4141608C2 (de) * 1991-12-17 1993-12-02 Eppendorf Geraetebau Netheler Pipettiervorrichtung
FI921648A0 (fi) * 1992-04-13 1992-04-13 Labsystems Oy Stegpipett.
US5364596A (en) * 1992-12-01 1994-11-15 Rainin Instrument Co., Inc. Manual pipette with plunger velocity governor, home position latch and trigger release
FI931806A0 (fi) * 1993-04-21 1993-04-21 Labsystems Oy Kolvpipett
DE9415847U1 (de) * 1994-09-30 1994-12-08 Ritter, Ralf, 86150 Augsburg Repetierpipette
FI961649A0 (fi) * 1996-04-15 1996-04-15 Labsystems Oy Spaerrpipett
FR2762671B1 (fr) * 1997-04-29 1999-07-16 D Autry Eric Marteau Dispositif de distribution de volumes sucessifs de liquide avec element d'accrochage aimante
FI108281B (fi) * 1999-07-07 2001-12-31 Biohit Oyj Imulaite ja menetelmä käytettäväksi imulaitteessa
FR2807340B1 (fr) * 2000-04-07 2002-12-06 Gilson Sa Pipette de prelevement d'echantillons liquides a mecanisme d'ejecteur de cone
FR2807339B1 (fr) * 2000-04-07 2002-12-13 Gilson Sa Pipette de prelevement d'echantillons liquides a ejecteur reglable
FR2836400B1 (fr) * 2002-02-25 2004-07-09 Junior Instruments Dispositif de pipetage automatique de precision
GB2504333B (en) * 2012-07-26 2016-10-05 Ttp Labtech Ltd Liquid dispensing device
DE102014109345A1 (de) 2014-07-04 2016-01-07 Eppendorf Ag Pipette zum Betätigen einer Spritze
BE1022747A9 (nl) * 2015-02-27 2016-10-03 Pilipili Productontwerp Nv Activator voor het opbouwen en vrijgeven van een zekere kracht

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2926691C2 (de) * 1979-07-02 1983-05-26 Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg Repetierpipette
US4099548A (en) * 1976-08-25 1978-07-11 Oxford Laboratories Inc. Hand-held pipette for repetitively dispensing precise volumes of liquid
FI60137C (fi) * 1979-03-23 1981-12-10 Suovaniemi Finnpipette Pipett
FI58875C (fi) * 1979-08-31 1981-05-11 Suovaniemi Finnpipette Pipett
JPS6035458B2 (ja) * 1980-08-02 1985-08-14 アイシン精機株式会社 刺しゆう枠

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202010010942U1 (de) 2010-08-03 2011-11-08 Brand Gmbh + Co Kg Pipette für ein Pipettensystem mit Pipette und Spritze
EP2415525A2 (de) 2010-08-03 2012-02-08 Brand GmbH + Co KG Pipette für ein Pipettensystem mit Pipette und Spritze
EP2415525A3 (de) * 2010-08-03 2014-07-02 Brand GmbH + Co KG Pipette für ein Pipettensystem mit Pipette und Spritze
EP4406655A3 (de) * 2020-06-22 2024-08-21 Eppendorf SE Pipette für den gebrauch mit einer einen kolben und einen zylinder aufweisenden pipettenspitze oder spritze
EP3928868B1 (de) * 2020-06-22 2024-11-27 Eppendorf SE Pipette für den gebrauch mit einer einen kolben und einen zylinder aufweisenden pipettenspitze oder spritze

Also Published As

Publication number Publication date
SU1373300A3 (ru) 1988-02-07
IT8467229A0 (it) 1984-03-12
DE3467860D1 (en) 1988-01-14
IT1178875B (it) 1987-09-16
JPS60501048A (ja) 1985-07-11
FI831239A0 (fi) 1983-04-13
WO1984004056A1 (en) 1984-10-25
EP0143796A1 (de) 1985-06-12
IT8467229A1 (it) 1985-09-12

Similar Documents

Publication Publication Date Title
EP0143796B1 (de) Dosierpipette
US4268481A (en) Pipette
US6295880B1 (en) Adjustable pipette
FI58875C (fi) Pipett
US3248950A (en) Stop mechanism for pipette filling device
US5879633A (en) Ratchet pipette
EP0566041B1 (de) Repetierpipette
JP4214269B2 (ja) ピペット
JPH0623283A (ja) 先端部除去器を備えたピペット
US5672320A (en) Repeating pipet having a plunger advance mechanism
JPS6229096B2 (de)
US5403553A (en) Jet part pipette
US4437586A (en) Mechanically actuated pipette dispenser
CN1416369A (zh) 人体工学的无复回弹簧的手动排气吸量管
US5696330A (en) Phase pipette
GB2045641A (en) Pipette
US4144761A (en) Handpipette
US5804144A (en) Piston pipette
US6708853B1 (en) Manual cookie press
EP0695220B1 (de) Kolbenhubpipette
US4306863A (en) Amalgam dispenser with lockable plugger
FI77166B (fi) Doseringspipett.
SU1242229A1 (ru) Пипеточный дозатор

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19841204

AK Designated contracting states

Designated state(s): AT BE CH DE FR GB LI LU NL SE

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE CH DE FR GB LI LU NL SE

REF Corresponds to:

Ref document number: 31150

Country of ref document: AT

Date of ref document: 19871215

Kind code of ref document: T

REF Corresponds to:

Ref document number: 3467860

Country of ref document: DE

Date of ref document: 19880114

ET Fr: translation filed
PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed
PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 19910329

Year of fee payment: 8

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 19910331

Year of fee payment: 8

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Effective date: 19921001

NLV4 Nl: lapsed or anulled due to non-payment of the annual fee
PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Effective date: 19921130

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

EPTA Lu: last paid annual fee
EAL Se: european patent in force in sweden

Ref document number: 84901351.1

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: LU

Payment date: 19960301

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: SE

Payment date: 19960318

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: AT

Payment date: 19960321

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 19960401

Year of fee payment: 13

Ref country code: BE

Payment date: 19960401

Year of fee payment: 13

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 19970320

Year of fee payment: 14

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 19970329

Ref country code: AT

Effective date: 19970329

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Effective date: 19970330

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Effective date: 19970331

Ref country code: CH

Effective date: 19970331

Ref country code: BE

Effective date: 19970331

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 19970528

Year of fee payment: 14

BERE Be: lapsed

Owner name: LABSYSTEMS OY

Effective date: 19970331

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

EUG Se: european patent has lapsed

Ref document number: 84901351.1

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 19980329

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 19980329

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 19981201