EP0160091A4 - Production d'hormones heterodimeriques de la fertilite chez l'homme. - Google Patents

Production d'hormones heterodimeriques de la fertilite chez l'homme.

Info

Publication number: EP0160091A4
Authority: EP; European Patent Office
Prior art keywords: production; human fertility; fertility hormones; heterodimeric human; heterodimeric
Prior art date: 1983-11-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19850900266

Other languages

German (de)

English (en)

Other versions

EP0160091A1 (fr

Inventor

Vermuri B Reddy

Nancy Hsiung

Anton K Beck

Edward George Bernstine

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Applied Research Systems ARS Holding NV

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-11-02

Filing date

1984-10-31

Publication date

1987-10-08

1983-11-02 Priority claimed from US06/548,228 external-priority patent/US4840896A/en

1984-10-31 Application filed by Individual filed Critical Individual

1985-11-06 Publication of EP0160091A1 publication Critical patent/EP0160091A1/fr

1987-10-08 Publication of EP0160091A4 publication Critical patent/EP0160091A4/fr

Status Withdrawn legal-status Critical Current

Links

230000035558 fertility Effects 0.000 title 1
229940088597 hormone Drugs 0.000 title 1
239000005556 hormone Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4715—Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Reproductive Health (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Wood Science & Technology (AREA)
Endocrinology (AREA)
Toxicology (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Gynecology & Obstetrics (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Pregnancy & Childbirth (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

EP19850900266 1983-11-02 1984-10-31 Production d'hormones heterodimeriques de la fertilite chez l'homme. Withdrawn EP0160091A4 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US54821183A	1983-11-02	1983-11-02
US06/548,228 US4840896A (en)	1983-11-02	1983-11-02	Heteropolymeric protein
US548228		2000-04-12

Publications (2)

Publication Number	Publication Date
EP0160091A1 EP0160091A1 (fr)	1985-11-06
EP0160091A4 true EP0160091A4 (fr)	1987-10-08

Family

ID=46229989

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19850900266 Withdrawn EP0160091A4 (fr)	1983-11-02	1984-10-31	Production d'hormones heterodimeriques de la fertilite chez l'homme.

Country Status (1)

Country	Link
EP (1)	EP0160091A4 (fr)

1984
- 1984-10-31 EP EP19850900266 patent/EP0160091A4/fr not_active Withdrawn

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 85, no. 3, 19th July 1976, page 205, abstract no. 15625m, Columbus, Ohio, US; R.C. SHOWNKEEN et al.: "Purification and properties of the subunits of human pituitary follicle-stimulating hormone", & J.ENDOCRINOL. 1976, 69(2), 263-73 *
See also references of WO8501958A1 *

Also Published As

Publication number	Publication date
EP0160091A1 (fr)	1985-11-06

Legal Events

Date	Code	Title	Description
1985-09-07	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1985-11-06	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB LI LU NL SE Designated state(s): AT BE CH DE FR GB LI LU NL SE
1986-01-15	17P	Request for examination filed	Effective date: 19851108
1987-11-25	A4	Supplementary search report drawn up and despatched	Effective date: 19871008
1990-04-18	17Q	First examination report despatched	Effective date: 19900305
1990-11-14	DIN1	Information on inventor provided before grant (deleted)
1990-12-05	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
1990-12-05	RIN1	Information on inventor provided before grant (corrected)	Inventor name: BERNSTINE, EDWARD GEORGE Inventor name: BECK, ANTON K. Inventor name: HSIUNG, NANCY Inventor name: REDDY, VERMURI B.
1992-02-25	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1992-04-15	18D	Application deemed to be withdrawn	Effective date: 19910917

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