EP0189391A2 - Tube pour échantillon de sang - Google Patents

Tube pour échantillon de sang Download PDF

Info

Publication number
EP0189391A2
EP0189391A2 EP86890008A EP86890008A EP0189391A2 EP 0189391 A2 EP0189391 A2 EP 0189391A2 EP 86890008 A EP86890008 A EP 86890008A EP 86890008 A EP86890008 A EP 86890008A EP 0189391 A2 EP0189391 A2 EP 0189391A2
Authority
EP
European Patent Office
Prior art keywords
tube
closure element
cap
sealing membrane
open end
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP86890008A
Other languages
German (de)
English (en)
Other versions
EP0189391A3 (fr
Inventor
Franz Konrad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CA Greiner and Soehne GmbH
Original Assignee
CA Greiner and Soehne GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CA Greiner and Soehne GmbH filed Critical CA Greiner and Soehne GmbH
Publication of EP0189391A2 publication Critical patent/EP0189391A2/fr
Publication of EP0189391A3 publication Critical patent/EP0189391A3/fr
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs

Definitions

  • the invention relates to a sealed, evacuable blood sample tube for a blood collection device with a hollow cylindrical holder, which has a double-ended hollow needle at one end and in the other, open end of which the blood sample tube can be inserted to such an extent that one needle end pierces the seal.
  • the tube is closed at its open end by a cap having a double jacket, which encloses the open end of the tube from the inside and outside, is press-fitted therein and carries a closure element which is made of a flat, preferably constant wall thickness film, e.g. consists of aluminum, which is provided on its side facing the inside of the tube with a continuous heat-sealable layer, the closure element additionally having a sealing membrane made of rubber-elastic material, e.g. Silicone rubber, is provided.
  • a tube for a vacuum blood collection system is known from DE-OS 2908817.
  • the closure element there forms a screw-on cap which has an opening, the edge of which presses a membrane forming the seal from a material which can be pierced by one end of the needle, sealingly against the open end of the blood test tube.
  • threads have to be made at its opening and at its closure cap, and furthermore, when the cap is screwed on, a careful sealing of the membrane between the cap and the end of the tube must be made.
  • Access to the sample taken with such a tube ultimately requires unscrewing the cap again, which is cumbersome and time consuming; in addition, it cannot be determined on the tube whether an unwanted opening has been carried out.
  • a flange is provided in the cap on which the closure element is fixed by means of the heat-sealable layer, the sealing membrane being outside the closure element but still inside the cap.
  • the object of the invention is to eliminate the drawbacks in the tubes of the latter types and to create a closure element which is easy to manufacture and handle.
  • this object is achieved in that the closure element closes the cap at its upper end by means of the heat-sealable layer and that the sealing membrane is arranged within the closure element.
  • the cap has a closed bottom part. In this way, the bottom part can support the desired press fit of the cap on the tube.
  • Another feature of the invention provides that a sleeve is arranged within the inner cap shell, which receives the sealing membrane. This training enables a substantial reduction in the volume of the sealing membrane consisting of expensive material.
  • a final feature of the invention is that on the inside of the inner jacket or sleeve protrusions, e.g. V-ribs are arranged, which engage in the sealing membrane.
  • This inner jacket 4 is provided on the inside, approximately halfway up, with a base part 5, which gives the cap or its inner jacket 4 increased rigidity and additionally increases the tightness of the tube.
  • the cap 1 carries on its upper side a closure 6 which is formed in the form of a circuit board from an aluminum foil 8 provided with a heat seal layer 7 and having a constant wall thickness. Such films are known per se. A 0.3 mm thick aluminum foil is expediently used.
  • the closure 6 is heat-sealed on the web part 3 of the cap 1 by means of the layer 7.
  • sealing pad 9 as a membrane, which consists of a rubber-elastic material, preferably silicone rubber and is arranged in the illustrated embodiment within a sleeve 10, which extends from the base part 5 upwards, etc. at a distance from the inner jacket 4.
  • a sleeve 10 which extends from the base part 5 upwards, etc. at a distance from the inner jacket 4.
  • the inside of the sleeve 10 is provided with protrusions in the form of V-ribs 11.
  • This sealing pad 9 has the property that when you pierce one end of the double-ended needle of the hollow cylindrical holder and pull the needle out again after the blood is drawn, it closes completely.
  • the tube 12 to be closed for example made of glass, is inserted with its open end 13 between the outer jacket 2 and the inner jacket 4, with an interference fit between these parts.
  • the outside of the outside jacket 2 can, as shown, be provided with grooves 14.
  • the interior of the tube 12 is under vacuum; this can be generated after the seal 6 has been heat-sealed and the sealing pad 9 has been applied.
  • the tube 12 e.g. also consist of plastic instead of glass. It is also possible to produce the closure 6 with a plastic film 8 instead of a metal film.
  • the bottom part 5 can also be designed in the form of a circular ring, that is to say have a central opening which, for example, has the same diameter as the inner diameter of the sleeve 10.
  • the sleeve 10 can also be omitted at all, so that the sealing pad 9 extends to the inner wall of the inner shell 4; in this case, the V-ribs 11 are formed on this inner wall.
  • the shape of these protrusions can also be different from that of continuous V-ribs, e.g. as individually spaced pyramids, hemispheres or the like.
  • the tube designed according to the invention can be used not only for taking blood, but also for taking other body fluids and also for similar purposes.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP86890008A 1985-01-24 1986-01-20 Tube pour échantillon de sang Withdrawn EP0189391A3 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT186/85 1985-01-24
AT0018685A AT380392B (de) 1985-01-24 1985-01-24 Blutprobenr!hrchen

Publications (2)

Publication Number Publication Date
EP0189391A2 true EP0189391A2 (fr) 1986-07-30
EP0189391A3 EP0189391A3 (fr) 1989-05-10

Family

ID=3483764

Family Applications (1)

Application Number Title Priority Date Filing Date
EP86890008A Withdrawn EP0189391A3 (fr) 1985-01-24 1986-01-20 Tube pour échantillon de sang

Country Status (6)

Country Link
US (1) US4664274A (fr)
EP (1) EP0189391A3 (fr)
JP (1) JPS61170437A (fr)
AT (1) AT380392B (fr)
AU (1) AU573418B2 (fr)
ZA (1) ZA86233B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5358641A (en) * 1989-10-27 1994-10-25 Helena Laboratories Corporation Column analyzer system and improved chromatograph column for use in the system
US7097057B2 (en) 1999-12-23 2006-08-29 Helvoet Pharma Belgium N.V. Closure device for a vacuum sample collector
CN102847572A (zh) * 2012-09-26 2013-01-02 无锡耐思生物科技有限公司 微量离心管结构

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988004154A1 (fr) * 1986-12-11 1988-06-16 Terumo Kabushiki Kaisha Tube de prelevement de sang
SE464344B (sv) * 1988-02-18 1991-04-15 Norden Pac Dev Ab Aendstycke, foerfarande foer dess montering paa roerformade hylsor samt anordning foer genomfoerande av foerfarandet
JPH04501994A (ja) * 1988-11-28 1992-04-09 ジョセフ　パーソンズ　ノミニーズ　プロプライエタリー　リミテッド キャップ
JPH02162229A (ja) * 1988-12-16 1990-06-21 Terumo Corp 採液管
DE4112209A1 (de) * 1991-04-13 1992-10-15 Behringwerke Ag Behaelterverschluss mit durchstossbarem verschlusskoerper
US5230427A (en) * 1991-06-12 1993-07-27 Ppg Industries, Inc. Sterilizable hermetically-sealed substantially glass container
US5494170A (en) * 1993-05-06 1996-02-27 Becton Dickinson And Company Combination stopper-shield closure
DE9418060U1 (de) * 1994-11-11 1996-03-14 SC - Sanguis Counting Kontrollblutherstellungs- und Vertriebs GmbH, 51588 Nümbrecht Probenröhre und Abschlußkappe, insesondere für Kapillar-Blutentnahme
DE19703921C1 (de) * 1997-02-03 1999-03-18 Sarstedt Walter Geraete Blutentnahmevorrichtung
US6066296A (en) * 1997-09-23 2000-05-23 Array Medical, Inc. Sample addition, reagent application, and testing chamber
AU744547B2 (en) * 1998-03-18 2002-02-28 Sekisui Chemical Co., Ltd. Plug body for vacuum specimen sampling container, vacuum specimen sampling container, vacuum specimen sampling system, vacuum specimen sampling holder, and thermoplastic elastomer composition for plug body
US6106783A (en) * 1998-06-30 2000-08-22 Microliter Analytical Supplies, Inc. Microplate assembly and closure
US6562300B2 (en) * 1998-08-28 2003-05-13 Becton, Dickinson And Company Collection assembly
US6716396B1 (en) 1999-05-14 2004-04-06 Gen-Probe Incorporated Penetrable cap
EP1066881A3 (fr) * 1999-07-09 2002-07-03 Becton Dickinson and Company Dispositif de prélèvement d'échantillons avec capuchon
US6382441B1 (en) * 2000-03-22 2002-05-07 Becton, Dickinson And Company Plastic tube and resealable closure having protective collar
KR20020068841A (ko) * 2001-02-23 2002-08-28 정삼채 진공 채혈관
ATE422965T2 (de) 2001-03-09 2009-03-15 Gen Probe Inc Verfahren zum entnehmen von flüssigkeit aus einem behälter mit durchdringbarem verschluss
JP2004532756A (ja) * 2001-06-18 2004-10-28 ベクトン・ディキンソン・アンド・カンパニー 多層容器および多層容器の形成方法
US20040097882A1 (en) * 2002-11-14 2004-05-20 Dibiasi Michael A. Self-aligning shield for syringe
TW593962B (en) * 2003-05-05 2004-06-21 Jiun-Guang Luo Flat end sealing type heat pipe and sealing method thereof
WO2005011495A1 (fr) * 2003-07-18 2005-02-10 Sekisui Chemical Co., Ltd. Recipient ferme hermetiquement et recipient collecteur de substance d'essai sous vide
US20110284550A1 (en) 2010-05-18 2011-11-24 Gerry Gersovitz Multi-Compartment Containers
US8915395B2 (en) 2003-09-23 2014-12-23 Gerry Gersovitz Multi-compartment container
US11225357B2 (en) 2003-09-23 2022-01-18 Gerry Gersovitz Multi-compartment container
ITMI20051057A1 (it) * 2005-06-08 2006-12-09 Copan Innovation Ltd Dispositivo di prelievo, raccolta e trasporto di campioni biologici
US8387811B2 (en) 2007-04-16 2013-03-05 Bd Diagnostics Pierceable cap having piercing extensions
US8387810B2 (en) * 2007-04-16 2013-03-05 Becton, Dickinson And Company Pierceable cap having piercing extensions for a sample container
GB0722385D0 (en) * 2007-11-14 2007-12-27 Novathera Ltd Vessel cap
EP2213374A1 (fr) * 2009-01-15 2010-08-04 Syntesys sas Bouchon de fermeture à répétition pour tube à essais
US10407214B2 (en) 2010-05-18 2019-09-10 Gerry Gersovitz Multi-compartment containers
CN104010945B (zh) * 2011-12-22 2019-01-01 凸版印刷株式会社 塞子
US12434889B2 (en) * 2022-12-09 2025-10-07 Instrumentation Laboratory Company Sealing systems

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL263437A (fr) *
US2603218A (en) * 1952-07-15 Stopper for
US2783908A (en) * 1953-02-13 1957-03-05 Glaxo Lab Ltd Closures for bottles, vials and the like
CH397953A (de) * 1959-09-21 1965-08-31 Rubberfabriek Helvoet N V Behälterverschluss
GB928842A (en) * 1960-04-11 1963-06-19 Allen & Hanburys Ltd Improvements relating to containers for fluids
FR1325077A (fr) * 1962-03-16 1963-04-26 Bouchon, en particulier pour flacon de perfusion sanguine
CH603168A5 (fr) * 1975-03-21 1978-08-15 Dematex Dev & Invest
US4089432A (en) * 1977-05-06 1978-05-16 The Upjohn Company Vial and closure
US4254884A (en) * 1978-10-20 1981-03-10 Toppan Printing Co., Ltd. Plug body for a container
AT368389B (de) * 1981-02-27 1982-10-11 C A Greiner Und Soehne Ges M B Mit einer dichtung verschlossenes, evakuierbares blutprobenroehrchen
DE3376194D1 (en) * 1982-10-08 1988-05-11 Terumo Corp Evacuated blood collecting device
US4517978A (en) * 1983-01-13 1985-05-21 Levin Paul D Blood sampling instrument
AT377907B (de) * 1983-01-27 1985-05-28 Greiner & Soehne C A Blutprobenroehrchen
AT379069B (de) * 1984-01-11 1985-11-11 Greiner & Soehne C A Blutprobenroehrchen

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5358641A (en) * 1989-10-27 1994-10-25 Helena Laboratories Corporation Column analyzer system and improved chromatograph column for use in the system
US5589063A (en) * 1989-10-27 1996-12-31 Helena Laboratories Corporation Column analyzer system and improved chromatograph column for use in the system
US5595664A (en) * 1989-10-27 1997-01-21 Helena Laboratories Corporation Column analyzer system and improved chromatograph column for use in the system
US7097057B2 (en) 1999-12-23 2006-08-29 Helvoet Pharma Belgium N.V. Closure device for a vacuum sample collector
CN102847572A (zh) * 2012-09-26 2013-01-02 无锡耐思生物科技有限公司 微量离心管结构

Also Published As

Publication number Publication date
ZA86233B (en) 1986-09-24
JPS61170437A (ja) 1986-08-01
ATA18685A (de) 1985-10-15
EP0189391A3 (fr) 1989-05-10
AU5262186A (en) 1986-07-31
AT380392B (de) 1986-05-12
AU573418B2 (en) 1988-06-09
US4664274A (en) 1987-05-12

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Inventor name: KONRAD, FRANZ