EP0284898A3 - Hinge peptide, son procédé de préparation et son emploi pour la préparation d'immunogènes synthétiques - Google Patents

Hinge peptide, son procédé de préparation et son emploi pour la préparation d'immunogènes synthétiques Download PDF

Info

Publication number
EP0284898A3
EP0284898A3 EP88104201A EP88104201A EP0284898A3 EP 0284898 A3 EP0284898 A3 EP 0284898A3 EP 88104201 A EP88104201 A EP 88104201A EP 88104201 A EP88104201 A EP 88104201A EP 0284898 A3 EP0284898 A3 EP 0284898A3
Authority
EP
European Patent Office
Prior art keywords
preparation
manufacturing synthetic
hinge
immunogenes
hinge peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP88104201A
Other languages
German (de)
English (en)
Other versions
EP0284898A2 (fr
Inventor
Erich Prof. Dr. Wünsch
Luis Prof.Dr. Moroder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften eV filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Publication of EP0284898A2 publication Critical patent/EP0284898A2/fr
Publication of EP0284898A3 publication Critical patent/EP0284898A3/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/866—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody fragment, e.g. fab', fab, fv, fc, heavy chain or light chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP88104201A 1987-04-02 1988-03-16 Hinge peptide, son procédé de préparation et son emploi pour la préparation d'immunogènes synthétiques Withdrawn EP0284898A3 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP87104867 1987-04-02
EP87104867 1987-04-02

Publications (2)

Publication Number Publication Date
EP0284898A2 EP0284898A2 (fr) 1988-10-05
EP0284898A3 true EP0284898A3 (fr) 1990-06-27

Family

ID=8196889

Family Applications (1)

Application Number Title Priority Date Filing Date
EP88104201A Withdrawn EP0284898A3 (fr) 1987-04-02 1988-03-16 Hinge peptide, son procédé de préparation et son emploi pour la préparation d'immunogènes synthétiques

Country Status (3)

Country Link
US (1) US5041533A (fr)
EP (1) EP0284898A3 (fr)
JP (1) JPS63258895A (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6558952B1 (en) * 1992-12-14 2003-05-06 Waratah Pharmaceuticals, Inc. Treatment for diabetes
US5683695A (en) * 1993-02-10 1997-11-04 United Biomedical, Inc. Production of recombinant proteins containing multiple antigenic determinants linked by flexible hinge domains
DE69433178T2 (de) 1993-10-14 2004-06-17 The Scripps Research Institute, La Jolla Rohr bestehend aus zyklischen peptiden
US7288623B2 (en) * 1993-10-14 2007-10-30 The Scripps Research Institute Cyclic peptide tube
GB9720054D0 (en) * 1997-09-19 1997-11-19 Celltech Therapeutics Ltd Biological products
US20040037818A1 (en) * 1998-07-30 2004-02-26 Brand Stephen J. Treatment for diabetes
IL165242A0 (en) * 2002-05-24 2005-12-18 Waratah Pharmaceuticals Inc Treatment for diabetes
EP1837031B1 (fr) * 2002-06-07 2009-10-14 Waratah Pharmaceuticals, Inc. Methodes et compositions pour le traitement du diabete
US20040229810A1 (en) * 2002-10-22 2004-11-18 Antonio Cruz Gastrin compositions and formulations, and methods of use and preparation
NZ544924A (en) * 2003-06-27 2009-03-31 Biogen Idec Inc Modified binding molecules comprising connecting peptides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415493A (en) * 1982-05-11 1983-11-15 Scripps Clinic And Research Foundation Immune modulator peptides
US4683221A (en) * 1986-01-09 1987-07-28 Scripps Clinic And Research Foundation Lymphocyte-activating polypeptides

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIOCHEMISTRY, Band 24, 1985, Seiten 6467-6474; W. ITO et al.: "Proton nuclear magnetic resonance study on the dynamics of the conformation of the hinge segment of human G1 immunoglobulin" *
PEPTIDE CHEMISTRY, 1987, Seiten 759-764; L. MORODER et al.: "Human immunoglobulin G1 hinge region. Synthesis of related peptides and their conformational features" *

Also Published As

Publication number Publication date
US5041533A (en) 1991-08-20
EP0284898A2 (fr) 1988-10-05
JPS63258895A (ja) 1988-10-26

Similar Documents

Publication Publication Date Title
DE3681466D1 (de) Insulin-receptor, seine reinigung, seine herstellung in rekombinanten zellen, dna hierfuer, antikoerper gegen den insulin-receptor und deren herstellung, sowie pharmazeutische zusammensetzungen, die diese antikoerper enthalten.
EP1803815A3 (fr) Promoteur homologue fort en hamster
CA2000786A1 (fr) 3-piperidinyl-1,2-benzisoxazoles
DE3750342D1 (de) Menschliches gamma-interferon-spezifisches Rezeptorprotein, Antikörper gegen dieses Protein, Verfahren zur Herstellung dieses Proteins und dieses Antikörpers und dieses Protein und diesen Antikörper enthaltende Zusammensetzungen.
DE3750733D1 (de) Verfahren zur Herstellung von Hyaluronsäure, dafür benötigte Bakterienstämme und kosmetische Zusammensetzung, welche Hyaluronsäure enthält.
DE3586189D1 (de) Menge und verfahren zur herstellung rekombinierter erzeugnisse in grosser ausbeute.
ATE121781T1 (de) Verwendung von dns-fragmenten, die ein signalpeptid kodieren zur sekretion von reifen proteinen in rekombinanten hefen, expressions- kassetten, transformierte hefen und verfahren zur herstellung dieser proteine.
ATE195148T1 (de) Prozess zur rekombinanten herstellung von hiv-2 - proteinen sowie zellen, die hiv-2 - proteine exprimiert
EP0284898A3 (fr) Hinge peptide, son procédé de préparation et son emploi pour la préparation d'immunogènes synthétiques
WO1995019435A3 (fr) Proteines de la region v du recepteur d'antigene des lymphocytes t et leurs procedes de preparation
DE3855122D1 (de) Artifizielles Gen, das für humane Serumalbumine kodiert, seine Verwendung und Verfahren zu seiner Herstellung
EP0231752A3 (fr) Peptides à activité vasorelaxante, natriurétique et diurétique, leur procédé de préparation, les agents les contenant et leur emploi
EP0291804A3 (fr) Protéines à effet de TNF
EP1142902A3 (fr) Analogues des oligonucléotides dérivées en position 3', avec des groupes non-nucléotidiques, leur préparation et leur utilisation
DE69013811D1 (de) Verfahren zur Herstellung von antiviralem Protein unter Benützung von E.coli-Transformant, das Gen, das für dieses Protein kodiert und E.coli-Vektor benützt in diesem Verfahren.
DE68907735D1 (de) Genfragmente, die die variable region eines anti-hiv-antikoerpers codieren, von diesen exprimierte chimaere anti-hiv-antikoerper und verfahren zu deren herstellung.
EP0249248A3 (fr) Dérivés de purine
EP0306870A3 (fr) Dérivés de l'interféron gamma, procédés, vecteurs et médicaments respectifs
EP0357024A3 (fr) Dipoprotéine I (OMPI) de Pseudomonas aéruginosa
DE58908935D1 (de) Kaltvulkanisierbare Siliconkautschukmasse, Verfahren zu ihrer Herstellung und Verwendung.
EP0177814A3 (fr) Anticorps contre les peptides et leurs utilisation dans la détection des produits d'oncogènes
ATE127478T1 (de) Onkogen kodierendes polypeptid, das wachstumsfaktoraktivität besitzt, verfahren zu seiner herstellung und verwendung.
EP0315118A3 (fr) ADN codant pour endothéline et son utilisant
ATE103989T1 (de) Monoklonale antikoerper gegen e7-protein des humanen papillomvirus typ 16, verfahren zu ihrer herstellung sowie ihre verwendung.
DE3751081D1 (de) [Leu 13] Motilin, dessen kodierende DNS-Moleküle und Verfahren zu dessen Herstellung.

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): BE CH DE FR GB IT LI SE

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): BE CH DE FR GB IT LI SE

17P Request for examination filed

Effective date: 19900727

17Q First examination report despatched

Effective date: 19920313

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19930123