EP0305111A3 - Composés de céphalosporine, procédé pour leur préparation et compositions pharmaceutiques les contenant - Google Patents

Composés de céphalosporine, procédé pour leur préparation et compositions pharmaceutiques les contenant Download PDF

Info

Publication number: EP0305111A3
Authority: EP; European Patent Office
Prior art keywords: preparation; pharmaceutical compositions; cephalosporin compounds; pharmaceutically acceptable; compounds
Prior art date: 1987-08-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19880307659

Other languages

German (de)

English (en)

Other versions

EP0305111A2 (fr

Inventor

Stephen Christopher Finch

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Beecham Group PLC

Original Assignee

Beecham Group PLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-22

Filing date

1988-08-18

Publication date

1991-04-03

1988-08-18 Application filed by Beecham Group PLC filed Critical Beecham Group PLC

1989-03-01 Publication of EP0305111A2 publication Critical patent/EP0305111A2/fr

1991-04-03 Publication of EP0305111A3 publication Critical patent/EP0305111A3/fr

Status Withdrawn legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
229930186147 Cephalosporin Natural products 0.000 title 1
-1 Cephalosporin compounds Chemical class 0.000 title 1
229940124587 cephalosporin Drugs 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
150000001450 anions Chemical class 0.000 abstract 1
239000003782 beta lactam antibiotic agent Substances 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000007942 carboxylates Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000002132 β-lactam antibiotic Substances 0.000 abstract 1
229940124586 β-lactam antibiotics Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EP19880307659 1987-08-22 1988-08-18 Composés de céphalosporine, procédé pour leur préparation et compositions pharmaceutiques les contenant Withdrawn EP0305111A3 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB878719875A GB8719875D0 (en)	1987-08-22	1987-08-22	Compounds
GB8719875		1987-08-22

Publications (2)

Publication Number	Publication Date
EP0305111A2 EP0305111A2 (fr)	1989-03-01
EP0305111A3 true EP0305111A3 (fr)	1991-04-03

Family

ID=10622671

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19880307659 Withdrawn EP0305111A3 (fr)	1987-08-22	1988-08-18	Composés de céphalosporine, procédé pour leur préparation et compositions pharmaceutiques les contenant

Country Status (10)

Country	Link
US (1)	US5028427A (fr)
EP (1)	EP0305111A3 (fr)
JP (1)	JPS6468379A (fr)
KR (1)	KR890003781A (fr)
AU (1)	AU2112588A (fr)
DK (1)	DK468788A (fr)
GB (1)	GB8719875D0 (fr)
NZ (1)	NZ225875A (fr)
PT (1)	PT88308A (fr)
ZA (1)	ZA886160B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102203100B (zh)	2008-10-31	2014-08-27	盐野义制药株式会社	具有邻苯二酚基团的头孢菌素
KR20130018845A (ko)	2010-04-05	2013-02-25	시오노기세야쿠 가부시키가이샤	카테콜기를 갖는 세펨 화합물
WO2011125966A1 (fr)	2010-04-05	2011-10-13	塩野義製薬株式会社	Composé céphème who portant un groupe pseudocatéchol
JP5852562B2 (ja)	2010-04-28	2016-02-03	塩野義製薬株式会社	新規なセフェム誘導体
EP2703406A4 (fr)	2011-04-28	2015-08-05	Shionogi & Co	Nouveau composé de cephème ayant la structure du catéchol ou une structure proche du catéchol
CN103619853A (zh)	2011-06-27	2014-03-05	盐野义制药株式会社	具有吡啶鎓基的头孢烯化合物
US10441115B2 (en) *	2016-02-11	2019-10-15	Gojo Industries, Inc.	High quality non-aerosol hand sanitizing foam
US10912426B2 (en)	2016-04-06	2021-02-09	Gojo Industries, Inc.	Sequentially activated multi-diaphragm foam pumps, refill units and dispenser systems

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0071395A1 (fr) *	1981-07-25	1983-02-09	Beecham Group Plc	Agents antibactériens bêta-lactamiques
EP0211656A2 (fr) *	1985-08-10	1987-02-25	Beecham Group Plc	Dérivés de céphalosporine, procédé pour leur préparation et les compositions pharmaceutiques les contenant

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8520155D0 (en)	1985-08-10	1985-09-18	Beecham Group Plc	Compounds

1987
- 1987-08-22 GB GB878719875A patent/GB8719875D0/en active Pending
1988
- 1988-08-18 EP EP19880307659 patent/EP0305111A3/fr not_active Withdrawn
- 1988-08-19 AU AU21125/88A patent/AU2112588A/en not_active Abandoned
- 1988-08-19 PT PT88308A patent/PT88308A/pt unknown
- 1988-08-19 NZ NZ225875A patent/NZ225875A/en unknown
- 1988-08-19 DK DK468788A patent/DK468788A/da not_active Application Discontinuation
- 1988-08-19 ZA ZA886160A patent/ZA886160B/xx unknown
- 1988-08-20 KR KR1019880010621A patent/KR890003781A/ko not_active Withdrawn
- 1988-08-22 US US07/235,388 patent/US5028427A/en not_active Expired - Fee Related
- 1988-08-22 JP JP63207966A patent/JPS6468379A/ja active Pending

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0071395A1 (fr) *	1981-07-25	1983-02-09	Beecham Group Plc	Agents antibactériens bêta-lactamiques
EP0211656A2 (fr) *	1985-08-10	1987-02-25	Beecham Group Plc	Dérivés de céphalosporine, procédé pour leur préparation et les compositions pharmaceutiques les contenant

Also Published As

Publication number	Publication date
EP0305111A2 (fr)	1989-03-01
PT88308A (pt)	1989-06-30
AU2112588A (en)	1989-02-23
GB8719875D0 (en)	1987-09-30
DK468788D0 (da)	1988-08-19
ZA886160B (en)	1989-09-27
KR890003781A (ko)	1989-04-18
US5028427A (en)	1991-07-02
JPS6468379A (en)	1989-03-14
NZ225875A (en)	1990-12-21
DK468788A (da)	1989-02-23

Legal Events

Date	Code	Title	Description
1989-01-14	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1989-03-01	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE
1989-11-02	17P	Request for examination filed	Effective date: 19890831
1991-02-12	PUAL	Search report despatched	Free format text: ORIGINAL CODE: 0009013
1991-04-03	AK	Designated contracting states	Kind code of ref document: A3 Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE
1992-02-06	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1992-03-25	18D	Application deemed to be withdrawn	Effective date: 19911004

Publication	Publication Date	Title
AU1331588A (en)	1988-09-29	Method for treatment of alcohol abuse
EP0395219A3 (fr)	1992-04-01	Céphalosporines et leurs homologues, procédé pour leur préparation et compositions pharmaceutiques
EP0305111A3 (fr)	1991-04-03	Composés de céphalosporine, procédé pour leur préparation et compositions pharmaceutiques les contenant
IE842559L (en)	1980-11-21	Preparing 6-beta-halopenicillanic acid derivatives
MY104937A (en)	1994-07-30	Cephalosporin derivatives and processes for their preparation
EP0137442A3 (fr)	1986-01-15	Dérivés de céphalosporine et procédé pour leur préparation
EP0359536A3 (fr)	1991-11-13	Dérivés de céphalosporine, leur procédé de préparation et compositions pharmaceutiques
IE801095L (en)	1981-01-09	Preparing pyrenzepine
IE812572L (en)	1982-05-17	Pharmaceutical preparation
EP0207497A3 (fr)	1988-05-18	Dérivé d'acide quinolonecarboxylique et son procédé de préparation
EP0354568A3 (fr)	1991-09-11	Dérivés du catéchol
AU645254B2 (en)	1994-01-13	Crystalline cephem acid addition salts and processes for their preparation
IE810452L (en)	1981-09-07	Orally administrable drug form
EP0354757A3 (fr)	1991-05-29	Céphalosporines et produits homologues, leur procédé de préparation et compositions pharmaceutiques les contenant
EP0379132A3 (fr)	1992-01-08	Dérivés de céphalosporine et leur procédé de préparation
EP0334281A3 (fr)	1991-08-28	Dérivés de céphalosporine et procédé de leur préparation
EP0295783A3 (fr)	1989-12-06	Dérivés de codéine
EP0363223A3 (fr)	1991-11-13	Dérivés de 3-aryloxyméthylcéphalosporine, leur préparation et applications pharmaceutiques
ES2000475A6 (es)	1988-03-01	Un procedimiento para la preparacion de cefalosporinas
AU1228988A (en)	1988-08-24	Cephalosporin compounds or their salts, process for their preparation, and pharmaceutical compositions
AU560185B2 (en)	1987-04-02	Penicillin derivatives
IE802045L (en)	1981-04-02	Penicillin derivatives
EP0159899A3 (fr)	1986-08-20	Esters de céphalosporine, leur préparation et utilisation
HUT53654A (en)	1990-11-28	Process for producing cefemcarboxylic acid compounds and pharmaceutical compositions comprising such compounds
EP0281092A3 (fr)	1990-05-09	Dérivés de céphalosporine et procédé pour leur préparation