EP0332026B1 - Tootbrush with slow release of disinfectant and anti-bacterial agents and method of manufacturing the same - Google Patents
Tootbrush with slow release of disinfectant and anti-bacterial agents and method of manufacturing the same Download PDFInfo
- Publication number
- EP0332026B1 EP0332026B1 EP89103503A EP89103503A EP0332026B1 EP 0332026 B1 EP0332026 B1 EP 0332026B1 EP 89103503 A EP89103503 A EP 89103503A EP 89103503 A EP89103503 A EP 89103503A EP 0332026 B1 EP0332026 B1 EP 0332026B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- bristles
- toothbrush
- agent
- anchor
- tuft
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000645 desinfectant Substances 0.000 title claims description 17
- 238000004519 manufacturing process Methods 0.000 title claims description 4
- 239000003242 anti bacterial agent Substances 0.000 title description 3
- 239000003814 drug Substances 0.000 claims description 17
- 239000003795 chemical substances by application Substances 0.000 claims description 16
- 229940079593 drug Drugs 0.000 claims description 16
- 230000001680 brushing effect Effects 0.000 claims description 13
- 239000000463 material Substances 0.000 claims description 11
- 239000011248 coating agent Substances 0.000 claims description 9
- 238000000576 coating method Methods 0.000 claims description 9
- 238000002483 medication Methods 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 238000004873 anchoring Methods 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 description 12
- 229910052751 metal Inorganic materials 0.000 description 7
- 239000002184 metal Substances 0.000 description 7
- 241000894006 Bacteria Species 0.000 description 6
- 210000003128 head Anatomy 0.000 description 4
- 241000233866 Fungi Species 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 229910001369 Brass Inorganic materials 0.000 description 2
- 208000010641 Tooth disease Diseases 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 239000010951 brass Substances 0.000 description 2
- 239000000551 dentifrice Substances 0.000 description 2
- 230000002538 fungal effect Effects 0.000 description 2
- 208000024693 gingival disease Diseases 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000005923 long-lasting effect Effects 0.000 description 2
- MOFOBJHOKRNACT-UHFFFAOYSA-N nickel silver Chemical compound [Ni].[Ag] MOFOBJHOKRNACT-UHFFFAOYSA-N 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 238000009732 tufting Methods 0.000 description 2
- 229920002818 (Hydroxyethyl)methacrylate Polymers 0.000 description 1
- WMOOOIUXYRHDEZ-UHFFFAOYSA-N 2,3,4-trichlorobenzaldehyde Chemical compound ClC1=CC=C(C=O)C(Cl)=C1Cl WMOOOIUXYRHDEZ-UHFFFAOYSA-N 0.000 description 1
- TYBHZVUFOINFDV-UHFFFAOYSA-N 2-bromo-6-[(3-bromo-5-chloro-2-hydroxyphenyl)methyl]-4-chlorophenol Chemical compound OC1=C(Br)C=C(Cl)C=C1CC1=CC(Cl)=CC(Br)=C1O TYBHZVUFOINFDV-UHFFFAOYSA-N 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 1
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 229940027983 antiseptic and disinfectant quaternary ammonium compound Drugs 0.000 description 1
- 229960000686 benzalkonium chloride Drugs 0.000 description 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 229960001927 cetylpyridinium chloride Drugs 0.000 description 1
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- -1 e.g. Polymers 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
- 239000010956 nickel silver Substances 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 150000003222 pyridines Chemical class 0.000 description 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 229960003500 triclosan Drugs 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000004636 vulcanized rubber Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B11/00—Brushes with reservoir or other means for applying substances, e.g. paints, pastes, water
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B11/00—Brushes with reservoir or other means for applying substances, e.g. paints, pastes, water
- A46B11/001—Brushes with reservoir or other means for applying substances, e.g. paints, pastes, water with integral reservoirs
- A46B11/0068—Brushes where the reservoir is specifically intended for solid substance that dissolves gradually
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B11/00—Brushes with reservoir or other means for applying substances, e.g. paints, pastes, water
- A46B11/0072—Details
- A46B11/0079—Arrangements for preventing undesired leakage or dispensing
- A46B11/0082—Means for closing, sealing or controlling the flow using capillary action
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B2200/00—Brushes characterized by their functions, uses or applications
- A46B2200/10—For human or animal care
- A46B2200/1066—Toothbrush for cleaning the teeth or dentures
Definitions
- the primary tool for every day cleaning of teeth remains the common toothbrush. Since the toothbrush frequently comes into contact with the oral environment and may be subsequently left in a non-sterile environment until subsequent use, the toothbrush bristles can harbour bacteria and upon re-use of the toothbrush, the bristles can become a source for introducing bacteria into the oral cavity.
- the toothbrush has not been used as a source of medication but, rather, as an applicator for dentrifice. There would be merit in using the toothbrush as such a medication source, preferably as a complement to the dentrifice if a viable and practical low-cost means for doing so could be found.
- U.S. Patent 914,501 is an early approach wherein a reservoir is formed along the sides of the bristles to contain liquid dentrifice.
- This disclosure fails to provide long-lasting means for release of dentrifice or other agents since the liquid dentrifice would be washed from the oral cavity with each use.
- the brushing head has tuft holes containing a disinfectant to be released during brushing.
- Figure 3 of U.K. Patent 1,026,738 discloses recesses 6 disposed annularly around the upper interior perimeter of tuft holes 4 to provide a source of dentrifice when the brush is immersed in water.
- This patent again, fails to teach how a long-lasting source of disinfectant and/or other medications can be maintained over extended periods or be absorbed by the bristles over such long periods, i.e., over a period of extended use, as opposed to prior art teachings which disclose systems which would be effective for only a single use.
- the drawing illustrates, in schematic form, a cross-section of a portion of the head of a toothbrush suitable for the present invention.
- toothbrushes of conventional manufacture are not sterile and, in fact, harbour bacteria which transfers into the oral cavity during repeated brushings.
- the primary instrument for tooth cleaning itself can be source of infection within the mouth.
- toothbrush which is capable of releasing medication effective against tooth and gum disease over extended periods of time, that is, during multiple uses of the toothbrush.
- the solution to these long-recognized needs is the device of the present invention wherein disinfectant, medication or a mixture thereof is contained in a slow-release material. Subsequently, during repeated brushings, the water and saliva present in the oral cavity during brushing seeps into the tuft holes and causes the release of measured amounts of the disinfectant and/or medication. These agents travel up the tuft hole and out of it and into the oral cavity during brushing. Moreover, at the end of brushing, there is sufficient disinfectant remaining on the bristles and toothbrush head and adjacent portions of the handle to sterilize the same so that bacteria will not build up on the brush and contaminate the mouth upon succeeding toothbrushings over an extended period of time, say about 2 to 3 months.
- the drawing shows, in schematic form, a cross-section of a portion of the head of a toothbrush suitable for the present invention.
- the device is generally designated 10 and has a brush head 11.
- Two tuft holes for the bristles, 15 and 16, are depicted in brush head 11.
- the bristles or filament 13 are inserted into the holes 15 and 16, most commonly by an anchor 17, typically composed of aluminum or an alloy such as brass or silver-nickel.
- the toothbrush In operation, the toothbrush is employed in the usual fashion, i.e., dentifrice is applied to the bristles and the brush is inserted into the oral cavity for brushing.
- the water and saliva generated during this process causes measured amounts of disinfectant and/or medication to pass from their capsule enclosures and up along the bristles out of the tuft holes and into the mouth.
- sufficient disinfectant remains on the bristles to render the same sterile, thereby preventing the formation of bacterial colonies and fungal growth which, in the case of prior art toothbrushes, infect the oral cavity when the toothbrush is next used.
- the slow-release material may be of natural or synthetic polymers, e.g., gelatin, polyvinylpyrrolidone and hydroxyethylmethacrylate.
- antimicrobial agents such as chlorhexidine, Triclosan, or bromochlorophene may be employed, as well as other known agents.
- a wide variety of medicaments effective to destroy bacteria and fungus may be employed, both for the purpose of preventing bacterial/fungus growth on the brush and to deliver such ingredients into the oral cavity.
- Hexetidene Phenols in general Trichlorophenyl Formaldehyde Quaternary Ammonium compounds e.g. Benzalkonium Chloride
- Pyridine Derivatives e.g. Cetylpyridinium chloride
- Hexachlorophane e.g., although the toothbrush of the present invention is well-suited for conventional brushing with a dentrifice, it may be used without the latter and thus be employed as a means of delivering suitable medications into the oral cavity.
- the anchor 17 - which is usually metal such as nickel-silver, brass, aluminum, etc.- is coated with the disinfectant and/or antibacterial/fungus agents described above.
- a water-swellable coating or a coating capable of releasing the above agent(s) in concentrations sufficient to achieve the disinfecting and medicinal purposes described when wet, is applied to the metal.
- the metal anchors are usually derived from a continuous spool of the metal(s) mentioned above and are passed to the tufting machine and cut to size in situ.
- the coating material may be, for example, a polyvinyl or similar polymer capable of forming a film, e.g., cast from alcohol.
- the coating can be applied to the spool of metal at the source of manufacture or just prior to the tufting process via a coating bath or spray. To retain sufficient material, a groove may be formed on one or both sides of the metal anchor to hold the coating material.
- a variation of the above is to form the metal anchor in two or more strips (not shown) and to apply the coating as a "sandwich" between two of the strips.
- the anchor can be made of high strength plastic which then can be coated with the agent(s) described above.
Landscapes
- Brushes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US165650 | 1980-07-03 | ||
| US16565088A | 1988-03-08 | 1988-03-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0332026A1 EP0332026A1 (en) | 1989-09-13 |
| EP0332026B1 true EP0332026B1 (en) | 1993-07-14 |
Family
ID=22599844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP89103503A Expired - Lifetime EP0332026B1 (en) | 1988-03-08 | 1989-02-28 | Tootbrush with slow release of disinfectant and anti-bacterial agents and method of manufacturing the same |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0332026B1 (da) |
| JP (1) | JPH027903A (da) |
| AU (1) | AU616483B2 (da) |
| BR (1) | BR8901058A (da) |
| CA (1) | CA1321290C (da) |
| DE (1) | DE68907502T2 (da) |
| DK (1) | DK169886B1 (da) |
| MX (1) | MX169824B (da) |
| PH (1) | PH27587A (da) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8240937B2 (en) | 2002-09-05 | 2012-08-14 | Colgate-Palmolive Company | Oral care implement with bead retention |
| US8282298B2 (en) | 2008-06-26 | 2012-10-09 | Colgate-Palmolive Company | Oral care implement |
| US8449211B2 (en) | 2002-09-05 | 2013-05-28 | Colgate-Palmolive Company | Oral care toothbrush |
| US8459892B2 (en) | 2008-06-25 | 2013-06-11 | Colgate-Palmolive Company | Oral care implement |
| USD700437S1 (en) | 2009-02-05 | 2014-03-04 | Colgate-Palmolive Company | Toothbrush |
| US8734042B2 (en) | 2010-03-31 | 2014-05-27 | Colgate-Palmolive Company | Oral care implement with rapid flavor release |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01101917A (ja) * | 1987-10-15 | 1989-04-19 | Sangi Co Ltd | 歯ブラシ |
| FR2643261A1 (fr) * | 1989-02-22 | 1990-08-24 | Tonelli Jean Charles | Perfectionnement aux dentifrices |
| DE19646519A1 (de) * | 1996-11-12 | 1998-05-14 | Pedex & Co Gmbh | Zahnpflegegerät und Verfahren zur Herstellung von Reinigungselementen für Zahnpflegegeräte |
| DE19818553C1 (de) * | 1998-04-24 | 1999-08-05 | Rueb F A Holding Gmbh | Verfahren zur Herstellung einer Zahnbürste aus Kunststoff |
| EP2537436B1 (en) * | 2002-09-05 | 2015-04-01 | Colgate-Palmolive Company | Disposable toothbrush |
| US7331731B2 (en) | 2002-09-05 | 2008-02-19 | Colgate-Palmolive Company | Oral care toothbrush |
| ITPD20130126A1 (it) * | 2013-05-10 | 2014-11-11 | Spazzolificio Piave Spa | Testa di spazzolino da denti |
| CN106794057B (zh) * | 2014-09-29 | 2020-07-03 | 皇家飞利浦有限公司 | 具有无泵流体输送系统的口腔护理设备 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE451728C (de) * | 1927-11-03 | Cornelius Gordijn Jr | Buerste mit einem mit Hohlraeumen zur Aufnahme eines Antiseptikums versehenen Buerstenkoerper | |
| JPS437396Y1 (da) * | 1965-10-12 | 1968-04-02 | ||
| JPS4318259Y1 (da) * | 1966-06-15 | 1968-07-29 | ||
| US3378870A (en) * | 1967-03-22 | 1968-04-23 | Matsunaga Kenji | Toothbrush |
| US4837007A (en) * | 1985-12-11 | 1989-06-06 | Lever Brothers Company | Fluoridating oral cavity |
-
1989
- 1989-02-28 DE DE89103503T patent/DE68907502T2/de not_active Expired - Fee Related
- 1989-02-28 EP EP89103503A patent/EP0332026B1/en not_active Expired - Lifetime
- 1989-03-01 AU AU30876/89A patent/AU616483B2/en not_active Ceased
- 1989-03-06 MX MX015159A patent/MX169824B/es unknown
- 1989-03-07 PH PH38298A patent/PH27587A/en unknown
- 1989-03-07 DK DK110989A patent/DK169886B1/da active
- 1989-03-07 CA CA000592981A patent/CA1321290C/en not_active Expired - Fee Related
- 1989-03-07 BR BR898901058A patent/BR8901058A/pt not_active IP Right Cessation
- 1989-03-08 JP JP1055999A patent/JPH027903A/ja active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8764332B2 (en) | 2002-09-05 | 2014-07-01 | Colgate-Palmolive Company | Oral care toothbrush |
| US9265337B2 (en) | 2002-09-05 | 2016-02-23 | Colgate-Palmolive Company | Oral care toothbrush |
| US8449211B2 (en) | 2002-09-05 | 2013-05-28 | Colgate-Palmolive Company | Oral care toothbrush |
| US8240937B2 (en) | 2002-09-05 | 2012-08-14 | Colgate-Palmolive Company | Oral care implement with bead retention |
| US9131767B2 (en) | 2008-06-25 | 2015-09-15 | Colgate-Palmolive Company | Oral care implement |
| US8459892B2 (en) | 2008-06-25 | 2013-06-11 | Colgate-Palmolive Company | Oral care implement |
| US8628264B2 (en) | 2008-06-26 | 2014-01-14 | Colgate-Palmolive Company | Oral care implement |
| US9149110B2 (en) | 2008-06-26 | 2015-10-06 | Colgate-Palmolive Company | Oral care implement |
| US8282298B2 (en) | 2008-06-26 | 2012-10-09 | Colgate-Palmolive Company | Oral care implement |
| USD700437S1 (en) | 2009-02-05 | 2014-03-04 | Colgate-Palmolive Company | Toothbrush |
| USD732831S1 (en) | 2009-02-05 | 2015-06-30 | Colgate-Palmolive Company | Toothbrush |
| USD782825S1 (en) | 2009-02-05 | 2017-04-04 | Colgate-Palmolive Company | Toothbrush |
| US8734042B2 (en) | 2010-03-31 | 2014-05-27 | Colgate-Palmolive Company | Oral care implement with rapid flavor release |
Also Published As
| Publication number | Publication date |
|---|---|
| AU3087689A (en) | 1989-09-14 |
| DE68907502T2 (de) | 1994-02-17 |
| PH27587A (en) | 1993-08-18 |
| JPH027903A (ja) | 1990-01-11 |
| DK110989D0 (da) | 1989-03-07 |
| DK110989A (da) | 1989-09-09 |
| AU616483B2 (en) | 1991-10-31 |
| CA1321290C (en) | 1993-08-17 |
| DK169886B1 (da) | 1995-03-27 |
| EP0332026A1 (en) | 1989-09-13 |
| MX169824B (es) | 1993-07-27 |
| DE68907502D1 (de) | 1993-08-19 |
| BR8901058A (pt) | 1989-10-24 |
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| STAA | Information on the status of an ep patent application or granted ep patent |
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| BERE | Be: lapsed |
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