EP0335726A3 - Verwendung von Thymopentin und Derivaten bei der Behandlung von HIV-Patienten - Google Patents

Verwendung von Thymopentin und Derivaten bei der Behandlung von HIV-Patienten Download PDF

Info

Publication number: EP0335726A3
Authority: EP; European Patent Office
Prior art keywords: thymopentin; derivatives; treatment; hiv; patients
Prior art date: 1988-03-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19890303179

Other languages

English (en)

French (fr)

Other versions

EP0335726A2 (de

Inventor

Gideon Goldstein

Robert Hirsch

Linda Meyerson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Immunobiology Research Institute Inc

Original Assignee

Immunobiology Research Institute Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-03-31

Filing date

1989-03-30

Publication date

1990-12-05

1989-03-30 Application filed by Immunobiology Research Institute Inc filed Critical Immunobiology Research Institute Inc

1989-10-04 Publication of EP0335726A2 publication Critical patent/EP0335726A2/de

1990-12-05 Publication of EP0335726A3 publication Critical patent/EP0335726A3/de

Status Withdrawn legal-status Critical Current

Links

102400000160 Thymopentin Human genes 0.000 title abstract 2
101800001703 Thymopentin Proteins 0.000 title abstract 2
PSWFFKRAVBDQEG-YGQNSOCVSA-N thymopentin Chemical compound NC(N)=NCCC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 PSWFFKRAVBDQEG-YGQNSOCVSA-N 0.000 title abstract 2
229960004517 thymopentin Drugs 0.000 title abstract 2
241000725303 Human immunodeficiency virus Species 0.000 abstract 2
206010058874 Viraemia Diseases 0.000 abstract 1
210000001124 body fluid Anatomy 0.000 abstract 1
239000010839 body fluid Substances 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
238000003501 co-culture Methods 0.000 abstract 1
210000003819 peripheral blood mononuclear cell Anatomy 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

EP19890303179 1988-03-31 1989-03-30 Verwendung von Thymopentin und Derivaten bei der Behandlung von HIV-Patienten Withdrawn EP0335726A3 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17591288A	1988-03-31	1988-03-31
US175912		1993-12-30

Publications (2)

Publication Number	Publication Date
EP0335726A2 EP0335726A2 (de)	1989-10-04
EP0335726A3 true EP0335726A3 (de)	1990-12-05

Family

ID=22642179

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19890303179 Withdrawn EP0335726A3 (de)	1988-03-31	1989-03-30	Verwendung von Thymopentin und Derivaten bei der Behandlung von HIV-Patienten

Country Status (3)

Country	Link
EP (1)	EP0335726A3 (de)
PT (1)	PT90169A (de)
WO (1)	WO1989009229A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1240353B (it) *	1990-03-30	1993-12-07	Poli Ind Chimica Spa	Formulazioni liposomiali di farmaci immunomodulatori per applicazionelocale ed aerosolica
DE4320201A1 (de) *	1993-06-18	1995-01-12	Asta Medica Ag	Verwendung von Cetrorelix und weiteren Nona- und Dekapeptiden zur Herstellung eines Arzneimittels zur Bekämpfung von Aids und zur Wachstumsstimulation
US6185561B1 (en)	1998-09-17	2001-02-06	Affymetrix, Inc.	Method and apparatus for providing and expression data mining database
JP2010539017A (ja) *	2007-09-11	2010-12-16	モンドバイオテックラボラトリーズアクチエンゲゼルシャフト	単独でまたはニューロキニン−ｂと組み合わせて用いる、治療剤としてのｒｆｒｐの使用
US20100204149A1 (en) *	2007-09-11	2010-08-12	Dorian Bevec	Use of octreotide as a therapeutic agent
WO2009046875A2 (en) *	2007-09-11	2009-04-16	Mondobiotech Laboratories Ag	Combination of splenopentin and thymopentin and the use thereof in medicine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4505853A (en) *	1983-11-18	1985-03-19	Ortho Pharmaceutical Corporation	Enzyme-resistant immunomodulatory peptides
US4547489A (en) *	1984-06-11	1985-10-15	Ortho Pharmaceutical Corporation	Conformationally restricted thymopentin-like compounds
US4629723A (en) *	1984-06-27	1986-12-16	Ortho Pharmaceutical Corporation	Potent thymopentin analogs

1989
- 1989-03-28 WO PCT/US1989/001271 patent/WO1989009229A1/en not_active Ceased
- 1989-03-30 PT PT90169A patent/PT90169A/pt not_active Application Discontinuation
- 1989-03-30 EP EP19890303179 patent/EP0335726A3/de not_active Withdrawn

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Acta Haemat., Vol. 78, suppl. 1, 1987, pages 84-90, S. Karger AG, Basel, CH; A. LAZZARIN et al.: "Experiences with immunomodulant agents in HIV infections", page 85, table 1, figure 1; page 86, table II; page 89, "Conclusions". *
G. Clin. Med., Vol. 68, nos. 6-7, 1987, pages 351-355; A. LATORRE et al.: "Effetti della timopentina e dell'interferone Alfa-2A ricombinante sulla biochemiluminescenza dei granulociti neutrofili in soggetti con infezione da virus HIV", page 351, summary; page 352, table 1; page 353, figure 1. *
Journal of Medical Virology, Vol. 23, 1987, pages 67-73, Alan R. Liss, Inc., J. ALBERT et al.: "Isolation of human immunodeficiency virus (HIV) from plasma during primary HIV infection", whole article. *
Surv. Immunol. Res., Vol. 4, suppl. 1, 1985, pages 58-62, S. Karger AG, Basel, CH; N. CLUMECK et al.: "Thymopentin treatment in AIDS and pre-AIDS patients", pages 60-61, "Discussion, summary". *
The New England Journal of Medicine, Vol. 317, 1987, pages 1125-1135; G.H. FRIEDLAND et al.: "Transmission of the human immunodeficiency virus", page 1125, right-hand column, line 4 - page 1126, line 7. *

Also Published As

Publication number	Publication date
EP0335726A2 (de)	1989-10-04
WO1989009229A1 (en)	1989-10-05
PT90169A (pt)	1989-11-10

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Legal Events

Date	Code	Title	Description
1989-08-19	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1989-10-04	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): BE CH DE ES FR GB IT LI
1990-10-16	PUAL	Search report despatched	Free format text: ORIGINAL CODE: 0009013
1990-12-05	AK	Designated contracting states	Kind code of ref document: A3 Designated state(s): BE CH DE ES FR GB IT LI
1990-12-05	RHK1	Main classification (correction)	Ipc: A61K 37/24
1991-02-27	17P	Request for examination filed	Effective date: 19901221
1991-04-11	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN
1991-05-15	18W	Application withdrawn	Withdrawal date: 19910309
1991-05-29	R18W	Application withdrawn (corrected)	Effective date: 19910309