EP0449562A3 - Use of r-fluoxetine as selective serotonin ic-receptor ligands - Google Patents

Use of r-fluoxetine as selective serotonin ic-receptor ligands Download PDF

Info

Publication number: EP0449562A3
Authority: EP; European Patent Office
Prior art keywords: fluoxetine; receptor ligands; selective serotonin; serotonin; selective
Prior art date: 1990-03-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19910302599

Other languages

English (en)

Other versions

EP0449562A2 (de

Inventor

David Wayne Robertson

David Taiwai Wong

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-03-29

Filing date

1991-03-26

Publication date

1992-03-18

1991-03-26 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1991-10-02 Publication of EP0449562A2 publication Critical patent/EP0449562A2/de

1992-03-18 Publication of EP0449562A3 publication Critical patent/EP0449562A3/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Addiction (AREA)
Child & Adolescent Psychology (AREA)
Pulmonology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EP19910302599 1990-03-29 1991-03-26 Use of r-fluoxetine as selective serotonin ic-receptor ligands Withdrawn EP0449562A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US50106090A	1990-03-29	1990-03-29
US501060		1990-03-29

Publications (2)

Publication Number	Publication Date
EP0449562A2 EP0449562A2 (de)	1991-10-02
EP0449562A3 true EP0449562A3 (en)	1992-03-18

Family

ID=23991998

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19910302599 Withdrawn EP0449562A3 (en)	1990-03-29	1991-03-26	Use of r-fluoxetine as selective serotonin ic-receptor ligands

Country Status (5)

Country	Link
EP (1)	EP0449562A3 (de)
JP (1)	JP3075577B2 (de)
AU (1)	AU633713B2 (de)
CA (1)	CA2039103A1 (de)
ZA (1)	ZA912277B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5589511A (en) *	1990-08-13	1996-12-31	Sepracor Inc.	Method for treating migraine headaches using optically pure S(+) fluoxetine
US5708035A (en) *	1991-02-04	1998-01-13	Sepracor Inc.	Methods of use and compositions of R(-) fluoxetine
DE69429895T2 (de)	1993-06-28	2002-08-29	American Home Products Corp., Madison	Neue Behandlungsmethoden durch Verwendung von Phenethylderivaten
ES2082723B1 (es) *	1994-07-20	1996-10-01	Lilly Sa	Formulacion farmaceutica de fluoxetina en forma dispersable.
US6548084B2 (en)	1995-07-20	2003-04-15	Smithkline Beecham Plc	Controlled release compositions
AU4100699A (en) *	1998-05-28	1999-12-13	Sepracor, Inc.	Compositions and methods employing r(-) fluoxetine and other active ingredients
EP4103177A4 (de) *	2020-02-11	2024-03-27	University of Virginia Patent Foundation	Zusammensetzungen und verfahren zur behandlung und/oder vorbeugung von augenerkrankungen

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989003692A1 (en) *	1987-10-22	1989-05-05	Massachusetts Institute Of Technology	Treating premenstrual or late luteal phase syndrome
US4868344A (en) *	1988-03-30	1989-09-19	Aldrich-Boranes, Inc.	Novel process of producing phenyl or substituted phenylalkylamine pharmaceutical agents and novel chiral intermediates of high enantiomeric purity useful therein

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3883606T2 (de) *	1987-05-04	1994-01-20	Lilly Co Eli	Verwendung von Fluoxetin zur Behandlung des Diabetes.
CA1327795C (en) *	1987-08-14	1994-03-15	Jules Freedman	Antidepressants which are aryloxy inadanamines
ZA898513B (en) *	1988-11-14	1991-07-31	Lilly Co Eli	Fluoxetine analog

1991
- 1991-03-26 CA CA002039103A patent/CA2039103A1/en not_active Abandoned
- 1991-03-26 ZA ZA912277A patent/ZA912277B/xx unknown
- 1991-03-26 EP EP19910302599 patent/EP0449562A3/en not_active Withdrawn
- 1991-03-27 AU AU73934/91A patent/AU633713B2/en not_active Ceased
- 1991-03-28 JP JP03064491A patent/JP3075577B2/ja not_active Expired - Fee Related

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989003692A1 (en) *	1987-10-22	1989-05-05	Massachusetts Institute Of Technology	Treating premenstrual or late luteal phase syndrome
US4868344A (en) *	1988-03-30	1989-09-19	Aldrich-Boranes, Inc.	Novel process of producing phenyl or substituted phenylalkylamine pharmaceutical agents and novel chiral intermediates of high enantiomeric purity useful therein

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J. MED. CHEM., vol. 31, no. 7, 1988, pages 1412-1417, American Chemical Society; D.W. ROBERTSON et al.: "Absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor" *
NEUROPSYCHOPHARMACOLOGY, vol. 5, no. 1, August 1991, pages 43-47, Elsevier Science Publishing Co., Inc.; D.T. WONG et al.: "Affinities of fluoxetine, its enantiomers, and other inhibitors of serotonin uptake for subtypes of serotonin receptors" *
PSYCHOPHARMACOLOGY, vol. 99, no. 2, 1989, pages 196-201, Springer-Verlag; J.C. NEILL et al.: "Selective reduction by serotonergic agents of hypertonic saline consumption in rats: evidence for possible 5-HT1c receptor mediation" *

Also Published As

Publication number	Publication date
AU633713B2 (en)	1993-02-04
ZA912277B (en)	1992-11-25
CA2039103A1 (en)	1991-09-30
JPH04221309A (ja)	1992-08-11
AU7393491A (en)	1991-10-03
EP0449562A2 (de)	1991-10-02
JP3075577B2 (ja)	2000-08-14

Legal Events

Date	Code	Title	Description
1991-08-15	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1991-10-02	17P	Request for examination filed	Effective date: 19910404
1991-10-02	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE
1992-01-28	PUAL	Search report despatched	Free format text: ORIGINAL CODE: 0009013
1992-03-18	AK	Designated contracting states	Kind code of ref document: A3 Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE
1994-03-16	17Q	First examination report despatched	Effective date: 19940201
1999-06-15	APCB	Communication from the board of appeal sent	Free format text: ORIGINAL CODE: EPIDOS OBAPE
1999-12-02	APCB	Communication from the board of appeal sent	Free format text: ORIGINAL CODE: EPIDOS OBAPE
1999-12-03	APCB	Communication from the board of appeal sent	Free format text: ORIGINAL CODE: EPIDOS OBAPE
2000-02-16	APCB	Communication from the board of appeal sent	Free format text: ORIGINAL CODE: EPIDOS OBAPE
2000-08-19	APAB	Appeal dossier modified	Free format text: ORIGINAL CODE: EPIDOS NOAPE
2005-10-05	APAF	Appeal reference modified	Free format text: ORIGINAL CODE: EPIDOSCREFNE
2007-09-14	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2007-10-17	18D	Application deemed to be withdrawn	Effective date: 20070825

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