EP0507772A4 - Nicht-melanozytische, eukaryotische zelle, die biologisch aktive menschliche tyrosinase konstitutiv exprimiert und deren verwendung. - Google Patents

Nicht-melanozytische, eukaryotische zelle, die biologisch aktive menschliche tyrosinase konstitutiv exprimiert und deren verwendung.

Info

Publication number
EP0507772A4
EP0507772A4 EP19900907793 EP90907793A EP0507772A4 EP 0507772 A4 EP0507772 A4 EP 0507772A4 EP 19900907793 EP19900907793 EP 19900907793 EP 90907793 A EP90907793 A EP 90907793A EP 0507772 A4 EP0507772 A4 EP 0507772A4
Authority
EP
European Patent Office
Prior art keywords
melanocytic
biologically active
active human
eucaryotic cell
constitutively expressing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900907793
Other languages
English (en)
French (fr)
Other versions
EP0507772A1 (de
Inventor
Brigitte Bouchard
Alan N Hougton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Memorial Sloan Kettering Cancer Center
Original Assignee
Memorial Sloan Kettering Cancer Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Memorial Sloan Kettering Cancer Center filed Critical Memorial Sloan Kettering Cancer Center
Publication of EP0507772A4 publication Critical patent/EP0507772A4/de
Publication of EP0507772A1 publication Critical patent/EP0507772A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/18—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with another compound as one donor, and incorporation of one atom of oxygen (1.14.18)
    • C12Y114/18001—Tyrosinase (1.14.18.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
EP90907793A 1989-04-26 1990-04-26 Nicht-melanozytische, eukaryotische zelle, die biologisch aktive menschliche tyrosinase konstitutiv exprimiert und deren verwendung Withdrawn EP0507772A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34396089A 1989-04-26 1989-04-26
US343960 1999-06-30

Publications (2)

Publication Number Publication Date
EP0507772A4 true EP0507772A4 (de) 1992-06-11
EP0507772A1 EP0507772A1 (de) 1992-10-14

Family

ID=23348412

Family Applications (1)

Application Number Title Priority Date Filing Date
EP90907793A Withdrawn EP0507772A1 (de) 1989-04-26 1990-04-26 Nicht-melanozytische, eukaryotische zelle, die biologisch aktive menschliche tyrosinase konstitutiv exprimiert und deren verwendung

Country Status (4)

Country Link
EP (1) EP0507772A1 (de)
JP (1) JPH04505249A (de)
CA (1) CA2054709A1 (de)
WO (1) WO1990012869A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2151544T3 (es) * 1992-12-22 2001-01-01 Ludwig Inst Cancer Res Metodos para la deteccion y el tratamiento de individuos con celulas anormales que expresan antigenos peptidos hla-a2/tirosinasa.
US5487974A (en) * 1992-12-22 1996-01-30 Ludwig Institute For Cancer-Research Method for detecting complexes containing human leukocyte antigen A2 (HLA-A2) molecules and a tyrosinase drived peptide on abnormal cells
US5571711A (en) * 1993-06-17 1996-11-05 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for BAGE tumor rejection antigen precursors
US6300057B1 (en) * 1997-02-06 2001-10-09 Large Scale Biology Corporation Melanins with improved ability to inhibit HIV replication
BR9910313B1 (pt) 1998-05-08 2008-11-18 reservatàrio de sangue/permutador tÉrmico combinado.
TW200718944A (en) * 1999-06-29 2007-05-16 Univ New York Screening methods for compounds that affect melanogenesis
CN1312375A (zh) * 2000-03-07 2001-09-12 上海博德基因开发有限公司 一种新的多肽——人酪氨酸酶12和编码这种多肽的多核苷酸
WO2014016118A1 (en) 2012-07-26 2014-01-30 Unilever N.V. A method of preparing recombinant human tyrosinase

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988002372A1 (en) * 1986-10-06 1988-04-07 Donald Guthrie Foundation For Medical Research, In A cDNA CLONE FOR HUMAN TYROSINASE

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988002372A1 (en) * 1986-10-06 1988-04-07 Donald Guthrie Foundation For Medical Research, In A cDNA CLONE FOR HUMAN TYROSINASE

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
NUCLEIC ACIDS RESEARCH. vol. 14, no. 6, 25 March 1986, ARLINGTON, VIRGINIA US pages 2413 - 2427; SHIBAHARA, S. ET AL.: 'Cloning and expression of cDNA encoding mouse tyrosinase' *
See also references of WO9012869A1 *
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE vol. 156, no. 4, December 1988, SENDAI, JP pages 403 - 414; SHIBAHARA, S. ET AL.: 'Molecular basis for the heterogeneity of human tyrosinase' *

Also Published As

Publication number Publication date
JPH04505249A (ja) 1992-09-17
WO1990012869A1 (en) 1990-11-01
EP0507772A1 (de) 1992-10-14
CA2054709A1 (en) 1990-10-27

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