EP0566237A3 - Inhibitoren der retroviralen Protease. - Google Patents

Inhibitoren der retroviralen Protease. Download PDF

Info

Publication number: EP0566237A3
Authority: EP; European Patent Office
Prior art keywords: protease inhibitors; retroviral protease; retroviral; inhibitors; protease
Prior art date: 1992-03-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19930301730

Other languages

English (en)

French (fr)

Other versions

EP0566237A2 (de

Inventor

Kwan Yuk Hui

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-03-13

Filing date

1993-03-08

Publication date

1994-10-26

1993-03-08 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1993-10-20 Publication of EP0566237A2 publication Critical patent/EP0566237A2/de

1994-10-26 Publication of EP0566237A3 publication Critical patent/EP0566237A3/de

Status Withdrawn legal-status Critical Current

Links

229940042399 direct acting antivirals protease inhibitors Drugs 0.000 title 1
239000000137 peptide hydrolase inhibitor Substances 0.000 title 1
230000001177 retroviral effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Virology (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

EP19930301730 1992-03-13 1993-03-08 Inhibitoren der retroviralen Protease. Withdrawn EP0566237A3 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US85285192A	1992-03-13	1992-03-13
US852851		1992-03-13

Publications (2)

Publication Number	Publication Date
EP0566237A2 EP0566237A2 (de)	1993-10-20
EP0566237A3 true EP0566237A3 (de)	1994-10-26

Family

ID=25314386

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP19930301730 Withdrawn EP0566237A3 (de)	1992-03-13	1993-03-08	Inhibitoren der retroviralen Protease.

Country Status (3)

Country	Link
EP (1)	EP0566237A3 (de)
JP (1)	JPH0673092A (de)
CA (1)	CA2091151A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5679688A (en)	1992-03-11	1997-10-21	Narhex Limited	Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US5888992A (en)	1992-03-11	1999-03-30	Narhex Limited	Polar substituted hydrocarbons
US6071895A (en)	1992-03-11	2000-06-06	Narhex Limited	Polar-substituted hydrocarbons

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5413999A (en) *	1991-11-08	1995-05-09	Merck & Co., Inc.	HIV protease inhibitors useful for the treatment of AIDS
EP0626178A1 (de) *	1993-05-17	1994-11-30	Ciba-Geigy Ag	Verwendung von Hemmstoffen von HIV-Aspartatproteasen zur Bekämpfung von Tumorerkrankungen
US5849691A (en) *	1996-02-20	1998-12-15	The United States Of America As Represented By The Department Of Health And Human Services	Peptidomimetic inhibitors of cathepsin D and plasmepsins I and II

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0374097A2 (de) *	1988-12-15	1990-06-20	Ciba-Geigy Ag	Verwendung von Peptidisosteren als retrovirale Proteasehemmer
EP0431784A2 (de) *	1989-11-20	1991-06-12	Eli Lilly And Company	Verfahren zur Behandlung retroviraler Infektionen
EP0498784A2 (de) *	1991-02-07	1992-08-12	Washington University	Retrovirale Protease-Inhibitoren

1993
- 1993-03-05 CA CA002091151A patent/CA2091151A1/en not_active Abandoned
- 1993-03-08 EP EP19930301730 patent/EP0566237A3/de not_active Withdrawn
- 1993-03-12 JP JP5052006A patent/JPH0673092A/ja not_active Withdrawn

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0374097A2 (de) *	1988-12-15	1990-06-20	Ciba-Geigy Ag	Verwendung von Peptidisosteren als retrovirale Proteasehemmer
EP0431784A2 (de) *	1989-11-20	1991-06-12	Eli Lilly And Company	Verfahren zur Behandlung retroviraler Infektionen
EP0498784A2 (de) *	1991-02-07	1992-08-12	Washington University	Retrovirale Protease-Inhibitoren

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
K.Y. HUI ET AL.: "A rational approach in the search for potent inhibitors against HIV protease", FASEB JOURNAL, vol. 5, no. 11, August 1991 (1991-08-01), BETHESDA, MD US, pages 2606 - 2610 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5679688A (en)	1992-03-11	1997-10-21	Narhex Limited	Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US5888992A (en)	1992-03-11	1999-03-30	Narhex Limited	Polar substituted hydrocarbons
US6071895A (en)	1992-03-11	2000-06-06	Narhex Limited	Polar-substituted hydrocarbons

Also Published As

Publication number	Publication date
CA2091151A1 (en)	1993-09-14
EP0566237A2 (de)	1993-10-20
JPH0673092A (ja)	1994-03-15

Legal Events

Date	Code	Title	Description
1993-09-03	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1993-10-20	17P	Request for examination filed	Effective date: 19930315
1993-10-20	AK	Designated contracting states	Kind code of ref document: A2 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
1994-09-05	PUAL	Search report despatched	Free format text: ORIGINAL CODE: 0009013
1994-10-26	AK	Designated contracting states	Kind code of ref document: A3 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
1997-03-12	17Q	First examination report despatched	Effective date: 19970124
1997-11-21	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1998-01-07	18D	Application deemed to be withdrawn	Effective date: 19970604

Publication	Publication Date	Title
ZA915269B (en)	1992-08-26	Retroviral protease inhibitors
IL102534A0 (en)	1993-01-14	Retroviral protease inhibitors
KR100190517B1 (en)	1999-06-01	Hiv protease inhibitors
HU9302080D0 (en)	1993-10-28	Amine-diole protease inhibitors
GR3030719T3 (en)	1999-11-30	Sulfonamide inhibitors of hiv-aspartyl protease.
EP0683772A4 (de)	1995-09-27	Retrovirale protease hemmende verbindungen.
HU9601508D0 (en)	1996-07-29	Dp-iv-serine protease inhibitors
EP0415981A4 (en)	1991-10-09	Retroviral protease inhibitors
EP0601322A3 (de)	1994-10-12	Adenosindeaminaseinhibitor.
PH31249A (en)	1998-06-18	Inhibitors of hiv protease.
EP0428849A3 (en)	1991-07-31	Retroviral protease inhibitors
IL108006A0 (en)	1994-04-12	Retroviral protease inhibitors
ZA899558B (en)	1990-08-29	Retroviral protease inhibitors
IL100161A0 (en)	1992-08-18	Retroviral protease inhibitors derived from 3-chloro-2-chloro-methyl-1-propene
EP0628035A4 (de)	1995-03-29	Retrovirale protease inhibitoren.
ZA949259B (en)	1995-11-29	Retroviral protease inhibiting compounds
ZA946325B (en)	1995-08-21	Retroviral protease inhibitors and combinations thereof.
EP0443560A3 (en)	1992-07-01	Hiv protease inhibitors
EP0566237A3 (de)	1994-10-26	Inhibitoren der retroviralen Protease.
EP0594586A4 (en)	1994-08-17	Hiv protease inhibitors
ZA928396B (en)	1993-05-12	HIV protease inhibitors.
ZA925360B (en)	1993-06-14	Retroviral protease inhibitors.
IL105450A0 (en)	1993-08-18	Hydroxy-carbamate retroviral protease inhibitors
MXPA94001311A (es)	2003-11-13	Combinaciones de inhibidores retrovirales.
IL100085A0 (en)	1992-08-18	Retroviral protease inhibitors

EP0566237A3 - Inhibitoren der retroviralen Protease. - Google Patents

Info

Links

Classifications

Landscapes

Applications Claiming Priority (2)

Publications (2)

Family

ID=25314386

Family Applications (1)

Country Status (3)

Cited By (3)

Families Citing this family (3)

Citations (3)

Patent Citations (3)

Non-Patent Citations (1)

Cited By (3)

Also Published As

Similar Documents

Legal Events