EP0600873A4 - Therapeutisch wirksame, örtliche anwendung von st1435. - Google Patents

Therapeutisch wirksame, örtliche anwendung von st1435.

Info

Publication number: EP0600873A4
Authority: EP; European Patent Office
Prior art keywords: therapeutically effective; topical application; effective topical; skin; blood
Prior art date: 1990-06-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

EP19910912052

Other languages

English (en)

French (fr)

Other versions

EP0600873B1 (de

EP0600873A1 (de

Inventor

Alfred Moo-Young

Ana Zepeda-Ortega

Horacio Bruno Croxatto

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Population Council Inc

Original Assignee

ROBERTSON DALE N

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-01

Filing date

1991-05-24

Publication date

1993-09-02

1991-05-24 Application filed by ROBERTSON DALE N filed Critical ROBERTSON DALE N

1991-05-24 Priority to EP96201585A priority Critical patent/EP0754456B1/de

1991-05-24 Priority to EP99202044A priority patent/EP1093816A3/de

1993-09-02 Publication of EP0600873A4 publication Critical patent/EP0600873A4/de

1994-06-15 Publication of EP0600873A1 publication Critical patent/EP0600873A1/de

1997-04-23 Application granted granted Critical

1997-04-23 Publication of EP0600873B1 publication Critical patent/EP0600873B1/de

2011-05-24 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

230000000699 topical effect Effects 0.000 title 1
239000008280 blood Substances 0.000 abstract 2
210000004369 blood Anatomy 0.000 abstract 2
238000001794 hormone therapy Methods 0.000 abstract 1
210000002966 serum Anatomy 0.000 abstract 1
230000002459 sustained effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Diabetes (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)

EP91912052A 1990-06-01 1991-05-24 Therapeutisch wirksame, örtliche anwendung von st1435 Expired - Lifetime EP0600873B1 (de)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
EP96201585A EP0754456B1 (de)	1990-06-01	1991-05-24	Herstellung von ST1435 enthaltenden pharmazeutischen Zusammensetzungen zur topischen Verwendung
EP99202044A EP1093816A3 (de)	1990-06-01	1991-05-24	Verwendung von ST1435 in Hormonaltherapie durch transdermale Verabreichung

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US53221590A	1990-06-01	1990-06-01
US532215		1990-06-01
PCT/US1991/003697 WO1991018570A1 (en)	1990-06-01	1991-05-24	Therapeutically effective topical application of st1435

Related Child Applications (2)

Application Number	Title	Priority Date	Filing Date
EP96201585A Division EP0754456B1 (de)	1990-06-01	1991-05-24	Herstellung von ST1435 enthaltenden pharmazeutischen Zusammensetzungen zur topischen Verwendung
EP96201585.5 Division-Into		1996-06-06

Publications (3)

Publication Number	Publication Date
EP0600873A4 true EP0600873A4 (de)	1993-09-02
EP0600873A1 EP0600873A1 (de)	1994-06-15
EP0600873B1 EP0600873B1 (de)	1997-04-23

Family

ID=24120850

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
EP91912052A Expired - Lifetime EP0600873B1 (de)	1990-06-01	1991-05-24	Therapeutisch wirksame, örtliche anwendung von st1435
EP99202044A Withdrawn EP1093816A3 (de)	1990-06-01	1991-05-24	Verwendung von ST1435 in Hormonaltherapie durch transdermale Verabreichung
EP96201585A Expired - Lifetime EP0754456B1 (de)	1990-06-01	1991-05-24	Herstellung von ST1435 enthaltenden pharmazeutischen Zusammensetzungen zur topischen Verwendung

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
EP99202044A Withdrawn EP1093816A3 (de)	1990-06-01	1991-05-24	Verwendung von ST1435 in Hormonaltherapie durch transdermale Verabreichung
EP96201585A Expired - Lifetime EP0754456B1 (de)	1990-06-01	1991-05-24	Herstellung von ST1435 enthaltenden pharmazeutischen Zusammensetzungen zur topischen Verwendung

Country Status (10)

Country	Link
US (1)	US5651973A (de)
EP (3)	EP0600873B1 (de)
JP (1)	JP2625254B2 (de)
AT (2)	ATE220912T1 (de)
CA (1)	CA2083404C (de)
DE (2)	DE69125855T2 (de)
DK (2)	DK0600873T3 (de)
ES (2)	ES2099747T3 (de)
GR (1)	GR3023312T3 (de)
WO (1)	WO1991018570A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991018570A1 (en) *	1990-06-01	1991-12-12	Robertson, Dale, N.	Therapeutically effective topical application of st1435
US6197327B1 (en)	1997-06-11	2001-03-06	Umd, Inc.	Device and method for treatment of dysmenorrhea
FR2776191B1 (fr) *	1998-03-23	2002-05-31	Theramex	Composition hormonale topique a effet systemique
US6503894B1 (en)	2000-08-30	2003-01-07	Unimed Pharmaceuticals, Inc.	Pharmaceutical composition and method for treating hypogonadism
US8529807B2 (en) *	2002-01-17	2013-09-10	Lts Lohmann Therapie-Systeme Ag	Method for neutralizing or recycling carrier materials for film-like coatings
GB2389793A (en) *	2002-06-18	2003-12-24	Euro Celtique Sa	Transdermal delivery system
US20040057983A1 (en)	2002-09-25	2004-03-25	David Schmidt	Biomolecular wearable apparatus
GEP20125432B (en)	2005-10-12	2012-03-26	Unimed Pharmaceuticals Llc	Improved testosterone gel and use thereof
US8602961B2 (en)	2008-05-15	2013-12-10	Lifewave Products Llc	Apparatus and method of stimulating elevation of glutathione levels in a subject
WO2010019365A1 (en) *	2008-08-12	2010-02-18	Optimer, Inc.	Method of reducing the distortion of the electromagnetic field
CN102753180A (zh)	2009-12-17	2012-10-24	人口委员会股份有限公司	Nestorone*/雌二醇透皮凝胶
US10322063B2 (en)	2013-03-19	2019-06-18	Genovus Biotechnologies Inc.	Muscle optimization device and method
US10888707B2 (en)	2013-03-19	2021-01-12	Genovus Biotechnologies Inc.	Muscle optimization device and method
EP3224410B1 (de)	2014-11-25	2019-06-05	Buckman Laboratories International, Inc	Filzkonditionierer und -reiniger

Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1292545A (en) *	1969-02-13	1972-10-11	Organon Labor Ltd	Medical plaster
US4292965A (en) *	1978-12-29	1981-10-06	The Population Council, Inc.	Intravaginal ring
US4911916A (en) *	1986-12-22	1990-03-27	Cygnus Research Corporation	Diffusion matrix for transdermal drug administration and transdermal drug delivery devices including same
EP0370220A1 (de) *	1988-10-27	1990-05-30	Schering Aktiengesellschaft	Mittel zur transdermalen Applikation enthaltend Gestoden
WO1991018572A1 (en) *	1990-06-01	1991-12-12	Robertson, Dale, N.	Device for transdermal administration of drugs

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1543245C3 (de) *	1965-11-26	1974-07-18	Merck Patent Gmbh, 6100 Darmstadt	16-Methy len-19-norprogesteronderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
US3854480A (en) *	1969-04-01	1974-12-17	Alza Corp	Drug-delivery system
US3948262A (en) *	1969-04-01	1976-04-06	Alza Corporation	Novel drug delivery device
US4144317A (en) *	1975-05-30	1979-03-13	Alza Corporation	Device consisting of copolymer having acetoxy groups for delivering drugs
US4379454A (en) *	1981-02-17	1983-04-12	Alza Corporation	Dosage for coadministering drug and percutaneous absorption enhancer
US4834978A (en) *	1984-10-01	1989-05-30	Biotek, Inc.	Method of transdermal drug delivery
US4818540A (en) *	1985-02-25	1989-04-04	Rutgers, The State University Of New Jersey	Transdermal fertility control system and process
CH674618A5 (de) *	1987-04-02	1990-06-29	Ciba Geigy Ag
WO1991018570A1 (en) *	1990-06-01	1991-12-12	Robertson, Dale, N.	Therapeutically effective topical application of st1435
US5122382A (en) *	1990-10-29	1992-06-16	Alza Corporation	Transdermal contraceptive formulations, methods and devices

1991
- 1991-05-24 WO PCT/US1991/003697 patent/WO1991018570A1/en not_active Ceased
- 1991-05-24 DE DE69125855T patent/DE69125855T2/de not_active Expired - Lifetime
- 1991-05-24 AT AT96201585T patent/ATE220912T1/de not_active IP Right Cessation
- 1991-05-24 EP EP91912052A patent/EP0600873B1/de not_active Expired - Lifetime
- 1991-05-24 JP JP3511213A patent/JP2625254B2/ja not_active Expired - Lifetime
- 1991-05-24 US US07/952,867 patent/US5651973A/en not_active Expired - Lifetime
- 1991-05-24 EP EP99202044A patent/EP1093816A3/de not_active Withdrawn
- 1991-05-24 DK DK91912052.7T patent/DK0600873T3/da active
- 1991-05-24 CA CA002083404A patent/CA2083404C/en not_active Expired - Lifetime
- 1991-05-24 ES ES91912052T patent/ES2099747T3/es not_active Expired - Lifetime
- 1991-05-24 DE DE69133077T patent/DE69133077T2/de not_active Expired - Lifetime
- 1991-05-24 EP EP96201585A patent/EP0754456B1/de not_active Expired - Lifetime
- 1991-05-24 AT AT91912052T patent/ATE151977T1/de not_active IP Right Cessation
- 1991-05-24 ES ES96201585T patent/ES2180690T3/es not_active Expired - Lifetime
- 1991-05-24 DK DK96201585T patent/DK0754456T3/da active
1997
- 1997-05-02 GR GR970400968T patent/GR3023312T3/el unknown

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1292545A (en) *	1969-02-13	1972-10-11	Organon Labor Ltd	Medical plaster
US4292965A (en) *	1978-12-29	1981-10-06	The Population Council, Inc.	Intravaginal ring
US4911916A (en) *	1986-12-22	1990-03-27	Cygnus Research Corporation	Diffusion matrix for transdermal drug administration and transdermal drug delivery devices including same
EP0370220A1 (de) *	1988-10-27	1990-05-30	Schering Aktiengesellschaft	Mittel zur transdermalen Applikation enthaltend Gestoden
WO1991018572A1 (en) *	1990-06-01	1991-12-12	Robertson, Dale, N.	Device for transdermal administration of drugs

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CONTRACEPTION vol. 25, no. 3, March 1982, pages 299 - 306 P.L[HTEENM[KI ET AL. 'pituitary and ovarian function during contraception with one subcutaneous implant releasing a progestin, ST-1435' *
P.L[HTEENM[KI 'contraceptive action of a synthetic progestin, st-1435 ÄthesisÜ' 1986 , UNIVERSITY OF HELSINKI , HELSINKI, FINLAND *

Also Published As

Publication number	Publication date
EP0754456A3 (de)	2000-02-02
DE69125855D1 (de)	1997-05-28
EP0754456B1 (de)	2002-07-24
EP0600873B1 (de)	1997-04-23
DK0600873T3 (da)	1997-05-20
DE69133077D1 (de)	2002-08-29
DK0754456T3 (da)	2002-11-11
US5651973A (en)	1997-07-29
DE69125855T2 (de)	1997-07-31
JP2625254B2 (ja)	1997-07-02
CA2083404C (en)	2001-02-20
EP1093816A3 (de)	2003-10-22
EP0754456A2 (de)	1997-01-22
CA2083404A1 (en)	1991-12-02
ES2099747T3 (es)	1997-06-01
ES2180690T3 (es)	2003-02-16
WO1991018570A1 (en)	1991-12-12
JPH07502253A (ja)	1995-03-09
ATE220912T1 (de)	2002-08-15
ATE151977T1 (de)	1997-05-15
GR3023312T3 (en)	1997-08-29
EP0600873A1 (de)	1994-06-15
EP1093816A2 (de)	2001-04-25
DE69133077T2 (de)	2002-11-07

Legal Events

Date	Code	Title	Description
1994-04-29	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1994-06-15	17P	Request for examination filed	Effective date: 19921007
1994-06-15	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE
1996-04-24	17Q	First examination report despatched	Effective date: 19951106
1996-05-29	GRAG	Despatch of communication of intention to grant	Free format text: ORIGINAL CODE: EPIDOS AGRA
1996-10-18	GRAH	Despatch of communication of intention to grant a patent	Free format text: ORIGINAL CODE: EPIDOS IGRA
1996-11-06	RAP1	Party data changed (applicant data changed or rights of an application transferred)	Owner name: THE POPULATION COUNCIL
1996-11-28	GRAH	Despatch of communication of intention to grant a patent	Free format text: ORIGINAL CODE: EPIDOS IGRA
1997-03-07	GRAA	(expected) grant	Free format text: ORIGINAL CODE: 0009210
1997-03-25	ITF	It: translation for a ep patent filed
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1997-04-23	DX	Miscellaneous (deleted)
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Publication	Publication Date	Title
GR3023312T3 (en)	1997-08-29	Therapeutically effective topical application of st1435.
AU549481B2 (en)	1986-01-30	Hair growing agent
DK0502092T3 (da)	1995-12-27	Oralt præparat til behandling af inflammatoriske tarmsygdomme
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AU4132397A (en)	1998-04-02	Therapeutic formulations containing venom or venom anti-serum either lone or in combination for the therapeutic prophylaxis and therapy of neoplasms
RU96104062A (ru)	1998-05-27	Средство "витадерм" в комплексной терапии ожоговых ран
ES481109A1 (es)	1980-09-01	Un metodo de preparacion de un extracto de stephania cepha- rantha.
WO2001041771A3 (de)	2001-12-27	Acetylsalicylsäure enthaltendes transdermales system zur behandlung von migräne
AU603375B2 (en)	1990-11-15	Therapeutic agent for the treatment of disorders associated with cerebral ischemia
ES469022A1 (es)	1978-11-16	Un procedimiento de preparacion del nuevo compuesto acido (2-isopropil-4-(2-tenoil)-5-metil)-fenoxi-acetico.
AU4246189A (en)	1990-04-12	Medicament for the treatment of diseases caused by retroviruses
JPS53107478A (en)	1978-09-19	Purification of urokinase
GB2011256A (en)	1979-07-11	Aluminium compounds or therapeutic use
NO172587C (no)	1993-08-11	Analogifremgangsmaate for fremstilling av terapeutisk aktive steroider med 19,11beta-brubinding
PT82421A (en)	1986-05-01	Process for the preparation of topical agents for inhibiting the melanin generation