EP0614345A4 - F TALE MEMBRANE TUBE FOR NERVES AND VESSELS. - Google Patents
F TALE MEMBRANE TUBE FOR NERVES AND VESSELS.Info
- Publication number
- EP0614345A4 EP0614345A4 EP19930900646 EP93900646A EP0614345A4 EP 0614345 A4 EP0614345 A4 EP 0614345A4 EP 19930900646 EP19930900646 EP 19930900646 EP 93900646 A EP93900646 A EP 93900646A EP 0614345 A4 EP0614345 A4 EP 0614345A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- nervous
- blood vessel
- fetal membrane
- membrane tubes
- transplants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/005—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/044—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/047—Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Surgery (AREA)
- Cardiology (AREA)
- Botany (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Graft Or Block Polymers (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79951791A | 1991-11-26 | 1991-11-26 | |
| US799517 | 1991-11-26 | ||
| PCT/US1992/010165 WO1993010722A2 (en) | 1991-11-26 | 1992-11-25 | Fetal membrane tubes for nerve and vessel grafts |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0614345A1 EP0614345A1 (en) | 1994-09-14 |
| EP0614345A4 true EP0614345A4 (en) | 1994-12-07 |
Family
ID=25176121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP19930900646 Ceased EP0614345A4 (en) | 1991-11-26 | 1992-11-25 | F TALE MEMBRANE TUBE FOR NERVES AND VESSELS. |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0614345A4 (sv) |
| JP (1) | JPH07501465A (sv) |
| CN (1) | CN1079912A (sv) |
| AU (1) | AU663150B2 (sv) |
| CA (1) | CA2124190A1 (sv) |
| FI (1) | FI942425L (sv) |
| IL (1) | IL103893A (sv) |
| NO (1) | NO941917L (sv) |
| NZ (1) | NZ245286A (sv) |
| RU (1) | RU94028108A (sv) |
| TW (1) | TW310273B (sv) |
| WO (1) | WO1993010722A2 (sv) |
| ZA (1) | ZA929119B (sv) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9400163D0 (en) * | 1994-01-06 | 1994-03-02 | Geistlich Soehne Ag | Membrane |
| US6334872B1 (en) | 1994-02-18 | 2002-01-01 | Organogenesis Inc. | Method for treating diseased or damaged organs |
| US5834029A (en) * | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
| GB9503492D0 (en) * | 1995-02-22 | 1995-04-12 | Ed Geistlich S Hne A G F R Che | Chemical product |
| CA2173508A1 (en) * | 1995-03-31 | 1996-10-01 | Tooru Yui | Medical device and method for producing the same |
| US20020095218A1 (en) | 1996-03-12 | 2002-07-18 | Carr Robert M. | Tissue repair fabric |
| US5733337A (en) * | 1995-04-07 | 1998-03-31 | Organogenesis, Inc. | Tissue repair fabric |
| JPH09122227A (ja) * | 1995-10-31 | 1997-05-13 | Bio Eng Lab:Kk | 医用材料およびその製造方法 |
| JPH09122225A (ja) * | 1995-10-31 | 1997-05-13 | Bio Eng Lab:Kk | 医用材料の原料膜材およびその製造方法 |
| JP3476631B2 (ja) * | 1995-12-21 | 2003-12-10 | 株式会社アムニオテック | ヒト由来の天然コラーゲン膜からなる医用材料 |
| TW528600B (en) * | 1996-11-20 | 2003-04-21 | Yasuhiko Shimizu | Artificial neural canal |
| US20050186283A1 (en) | 1997-10-10 | 2005-08-25 | Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie | Collagen carrier of therapeutic genetic material, and method |
| US9034315B2 (en) | 1997-10-10 | 2015-05-19 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Cell-charged multi-layer collagen membrane |
| US8858981B2 (en) | 1997-10-10 | 2014-10-14 | Ed. Geistlich Soehne Fuer Chemistrie Industrie | Bone healing material comprising matrix carrying bone-forming cells |
| CN1101704C (zh) * | 1998-05-28 | 2003-02-19 | 南京市鼓楼医院 | 用人脐动脉作为血管移植物的制备工艺 |
| MXPA00012064A (es) | 1998-06-05 | 2003-04-22 | Organogenesis Inc | Protesis de injerto tubular biodisenadas. |
| CA2334228C (en) | 1998-06-05 | 2010-09-28 | Organogenesis Inc. | Bioengineered vascular graft support prostheses |
| CA2334364C (en) | 1998-06-05 | 2011-01-04 | Organogenesis Inc. | Bioengineered flat sheet graft prostheses |
| DE69940507D1 (de) | 1998-06-05 | 2009-04-16 | Organogenesis Inc | Biotechnisch erzeugte gefässprothese für die implantation |
| WO1999063908A1 (en) * | 1998-06-10 | 1999-12-16 | Tapic International Co., Ltd. | Artificial neural tube |
| CZ301649B6 (cs) * | 2000-06-28 | 2010-05-12 | Ed. Geistlich Soehne Ag Fur Chemische Industrie Incorporated Under The Laws Of Switzerland | Trubice pro regeneraci nervu a zpusob jejich výroby |
| US6773723B1 (en) * | 2000-08-30 | 2004-08-10 | Depuy Acromed, Inc. | Collagen/polysaccharide bilayer matrix |
| AU784394B2 (en) | 2001-04-27 | 2006-03-23 | Geistlich Pharma Ag | Method and membrane for mucosa regeneration |
| DE10141652B4 (de) * | 2001-08-24 | 2011-04-07 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung |
| WO2003020327A2 (en) * | 2001-09-06 | 2003-03-13 | Bone Sa | A cross-linked collagenous biomaterial |
| CA2412012C (en) | 2001-11-20 | 2011-08-02 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Resorbable extracellular matrix containing collagen i and collagen ii for reconstruction of cartilage |
| CN100368534C (zh) * | 2003-05-01 | 2008-02-13 | 四川大学华西医院 | 生物衍生羊膜、复合生物衍生羊膜及其制备方法 |
| CN1986001B (zh) * | 2005-12-20 | 2011-09-14 | 广东冠昊生物科技股份有限公司 | 生物护创膜 |
| US8372437B2 (en) | 2006-08-17 | 2013-02-12 | Mimedx Group, Inc. | Placental tissue grafts |
| EP4559488A3 (en) | 2007-09-07 | 2025-08-13 | MiMedx Group, Inc. | Placental tissue grafts and improved methods of preparing and using the same |
| US20110152898A1 (en) * | 2008-05-09 | 2011-06-23 | The General Hospital Corporation | Tissue engineered constructs |
| US20140205646A1 (en) | 2011-02-14 | 2014-07-24 | Mimedx Group, Inc. | Tissue grafts modified with a cross-linking agent and method of making and using the same |
| WO2012112441A1 (en) * | 2011-02-14 | 2012-08-23 | Mimedx Group Inc. | Laminated tissue grafts composed of wharton's jelly and methods of making and using the same |
| US9585983B1 (en) | 2011-10-12 | 2017-03-07 | BioDlogics, LLC | Wound covering and method of preparation |
| EP2793745B1 (en) | 2011-12-22 | 2019-07-31 | MIMEDX Group Inc. | Cross-linked dehydrated placental tissue grafts and methods for making and using the same |
| US11338063B2 (en) * | 2012-08-15 | 2022-05-24 | Mimedx Group, Inc. | Placental tissue grafts modified with a cross-linking agent and methods of making and using the same |
| US9789138B1 (en) | 2013-03-06 | 2017-10-17 | BioDlogics, LLC | Neural repair construct and method of use |
| US11116871B2 (en) | 2015-09-17 | 2021-09-14 | Stimlabs Llc | Compositions derived from placenta and methods of producing the same |
| US11154641B2 (en) | 2017-12-22 | 2021-10-26 | Stimlabs Llc | Translucent, dehydrated placental tissue and methods of producing and using the same |
| CN113304321B (zh) * | 2021-06-01 | 2022-08-26 | 山东隽秀生物科技股份有限公司 | 一种生物膜材料及其制备方法与在修复神经中的应用 |
| US11925532B2 (en) | 2021-12-10 | 2024-03-12 | Vivex Biologics Group, Inc. | Vented wound dressing barrier |
| AU2023299174A1 (en) | 2022-06-29 | 2025-01-16 | Biostem Technologies, Inc. | Sterile human placental allografts having a plurality of slits, openings, and/or fenestrations formed thereon |
| USD1085424S1 (en) | 2022-11-18 | 2025-07-22 | Biostem Technologies, Inc. | Fenestrated human placental allograft |
| USD1085425S1 (en) | 2022-11-18 | 2025-07-22 | Biostem Technologies, Inc. | Fenestrated human placental allograft |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0333328A2 (en) * | 1988-02-17 | 1989-09-20 | Genethics Limited | Clinical developments using amniotic cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL47062A (en) * | 1975-04-10 | 1979-07-25 | Yeda Res & Dev | Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde |
| US4894063A (en) * | 1983-05-24 | 1990-01-16 | Baxter International Inc. | Barrier layer for implantable tendons and ligaments |
| US5019087A (en) * | 1986-10-06 | 1991-05-28 | American Biomaterials Corporation | Nerve regeneration conduit |
| US5026381A (en) * | 1989-04-20 | 1991-06-25 | Colla-Tec, Incorporated | Multi-layered, semi-permeable conduit for nerve regeneration comprised of type 1 collagen, its method of manufacture and a method of nerve regeneration using said conduit |
-
1992
- 1992-11-25 FI FI942425A patent/FI942425L/sv not_active Application Discontinuation
- 1992-11-25 AU AU32245/93A patent/AU663150B2/en not_active Ceased
- 1992-11-25 EP EP19930900646 patent/EP0614345A4/en not_active Ceased
- 1992-11-25 CA CA002124190A patent/CA2124190A1/en not_active Abandoned
- 1992-11-25 RU RU94028108/14A patent/RU94028108A/ru unknown
- 1992-11-25 WO PCT/US1992/010165 patent/WO1993010722A2/en not_active Ceased
- 1992-11-25 JP JP5510233A patent/JPH07501465A/ja active Pending
- 1992-11-25 ZA ZA929119A patent/ZA929119B/xx unknown
- 1992-11-26 IL IL10389392A patent/IL103893A/xx not_active IP Right Cessation
- 1992-11-26 NZ NZ245286A patent/NZ245286A/en unknown
- 1992-11-26 CN CN92114817A patent/CN1079912A/zh active Pending
- 1992-12-15 TW TW081110056A patent/TW310273B/zh active
-
1994
- 1994-05-24 NO NO941917A patent/NO941917L/no unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0333328A2 (en) * | 1988-02-17 | 1989-09-20 | Genethics Limited | Clinical developments using amniotic cells |
Also Published As
| Publication number | Publication date |
|---|---|
| IL103893A (en) | 1997-02-18 |
| JPH07501465A (ja) | 1995-02-16 |
| CN1079912A (zh) | 1993-12-29 |
| RU94028108A (ru) | 1996-06-20 |
| AU663150B2 (en) | 1995-09-28 |
| NO941917D0 (no) | 1994-05-24 |
| AU3224593A (en) | 1993-06-28 |
| FI942425A0 (sv) | 1994-05-25 |
| FI942425A7 (sv) | 1994-05-25 |
| NZ245286A (en) | 1995-06-27 |
| CA2124190A1 (en) | 1993-06-10 |
| WO1993010722A3 (en) | 1993-06-24 |
| NO941917L (no) | 1994-05-24 |
| WO1993010722A2 (en) | 1993-06-10 |
| FI942425L (sv) | 1994-05-25 |
| EP0614345A1 (en) | 1994-09-14 |
| TW310273B (sv) | 1997-07-11 |
| IL103893A0 (en) | 1993-04-04 |
| ZA929119B (en) | 1994-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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| 17P | Request for examination filed |
Effective date: 19940509 |
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| AK | Designated contracting states |
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| A4 | Supplementary search report drawn up and despatched | ||
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| 17Q | First examination report despatched |
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| GRAG | Despatch of communication of intention to grant |
Free format text: ORIGINAL CODE: EPIDOS AGRA |
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| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
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| 18R | Application refused |
Effective date: 19990830 |