EP0651650A4 - METHODE ZUR BEHANDLUNG VON AUGENKRANKHEITEN MITTELS TGF--g(b). - Google Patents

METHODE ZUR BEHANDLUNG VON AUGENKRANKHEITEN MITTELS TGF--g(b).

Info

Publication number
EP0651650A4
EP0651650A4 EP93917021A EP93917021A EP0651650A4 EP 0651650 A4 EP0651650 A4 EP 0651650A4 EP 93917021 A EP93917021 A EP 93917021A EP 93917021 A EP93917021 A EP 93917021A EP 0651650 A4 EP0651650 A4 EP 0651650A4
Authority
EP
European Patent Office
Prior art keywords
tgf
ophthalmic disorders
treating ophthalmic
treating
disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP93917021A
Other languages
English (en)
French (fr)
Other versions
EP0651650A1 (de
Inventor
Bert M Glaser
Bruce B Pharriss
Ann F Hanham
George A Ksander
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celtrix Pharmaceuticals Inc
Original Assignee
Celtrix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celtrix Pharmaceuticals Inc filed Critical Celtrix Pharmaceuticals Inc
Publication of EP0651650A1 publication Critical patent/EP0651650A1/de
Publication of EP0651650A4 publication Critical patent/EP0651650A4/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
EP93917021A 1992-07-08 1993-07-08 METHODE ZUR BEHANDLUNG VON AUGENKRANKHEITEN MITTELS TGF--g(b). Ceased EP0651650A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US91083492A 1992-07-08 1992-07-08
US910834 1992-07-08
US877893A 1993-01-22 1993-01-22
US8778 1993-01-22
PCT/US1993/006420 WO1994001124A1 (en) 1992-07-08 1993-07-08 METHOD OF TREATING OPHTHALMIC DISORDERS USING TGF-$g(b)

Publications (2)

Publication Number Publication Date
EP0651650A1 EP0651650A1 (de) 1995-05-10
EP0651650A4 true EP0651650A4 (de) 1996-04-17

Family

ID=26678611

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93917021A Ceased EP0651650A4 (de) 1992-07-08 1993-07-08 METHODE ZUR BEHANDLUNG VON AUGENKRANKHEITEN MITTELS TGF--g(b).

Country Status (5)

Country Link
EP (1) EP0651650A4 (de)
JP (1) JPH08502033A (de)
AU (1) AU4668193A (de)
CA (1) CA2138644A1 (de)
WO (1) WO1994001124A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688765A (en) * 1992-04-21 1997-11-18 The Schepens Eye Research Institute, Inc. Ocular therapy in Sjogren's syndrome using topically applied androgensor TGF-β
US5411940A (en) * 1993-09-29 1995-05-02 Alcon Laboratories, Inc. Use of TGF-β3 to reduce the formation of scar tissue in response to corneal trauma
EP0670733A1 (de) * 1993-09-29 1995-09-13 Alcon Laboratories, Inc. Zusammensetzungen welche wachstumsfaktoren und antineoplastische mitteln enthalten
US5449671A (en) * 1993-09-29 1995-09-12 Alcon Laboratories, Inc. Use of TGF-β3, to prevent or retard fistula closure following glaucoma filtration surgery
CA2149528A1 (en) * 1993-09-29 1995-04-06 Billie M. York Compositions containing growth factors and antimetabolites
ATE315939T1 (de) * 1993-11-19 2006-02-15 Univ Sydney Verfahren zur prophylaxe oder kontrolle des katarakts
AU688409B2 (en) * 1993-11-19 1998-03-12 University Of Sydney, The A method for preventing or controlling cataract
US5827702A (en) * 1994-10-31 1998-10-27 Genentech, Inc. Ocular gene therapy
AU5261898A (en) * 1996-12-04 1998-06-29 Abbot F. Clark Tgfalpha for the treatment of ocular hypertension and glaucoma
US6750052B1 (en) 1997-07-23 2004-06-15 The Brigham And Women's Hospital, Inc. Lens epithelial cell derived growth factor
EP1066382A1 (de) * 1997-07-23 2001-01-10 Brigham & Women's Hospital, Inc. Lensepithelzellen erhältlicher wachstumsfaktor
US6331523B1 (en) 1998-03-12 2001-12-18 Genentech, Inc. Method of enhancing the survival of retinal neurons and treating ocular diseases using FGF-5
CN1172673C (zh) * 1998-11-23 2004-10-27 诺瓦提斯公司 星形孢菌素衍生物在制备治疗眼睛新血管生成性疾病的药物中的应用
AU3737500A (en) * 1999-03-12 2000-09-28 Genentech Inc. Method of preventing the death of retinal neurons and treating ocular diseases
AU6391000A (en) * 1999-07-28 2001-02-19 Genentech Inc. Method of preventing the injury or death of retinal cells and treating ocular diseases
EP1252895A4 (de) * 2000-01-31 2003-04-16 Santen Pharmaceutical Co Ltd Heilmittel für ophthalmologische zustände
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
EP2627292B1 (de) 2010-10-15 2018-10-10 Clearside Biomedical, Inc. Vorrichtung für okularen zugang
KR102467714B1 (ko) 2012-11-08 2022-11-16 클리어사이드 바이오메디컬, 인코포레이드 인간 대상체에서 안구 질병을 치료하기 위한 방법 및 장치
AU2014259694B2 (en) 2013-05-03 2018-11-08 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
RU2540504C1 (ru) * 2013-12-26 2015-02-10 Федеральное государственное бюджетное учреждение "Московский научно-исследовательский институт глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации Способ прогнозирования риска развития поздней отслойки сетчатки у детей с рубцовой ретинопатией недоношенных
WO2015142855A1 (en) * 2014-03-17 2015-09-24 University Of Virginia Patent Foundation Compositions and methods for treating retinopathy
US9844556B2 (en) 2015-03-25 2017-12-19 Megumi Honjo Preventive/therapeutic method and preventive/therapeutic agent for complications after cataract surgery
WO2017139375A1 (en) 2016-02-10 2017-08-17 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
WO2017192565A1 (en) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
US10973681B2 (en) 2016-08-12 2021-04-13 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
US12090294B2 (en) 2017-05-02 2024-09-17 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
CN111803623B (zh) * 2020-07-31 2024-07-02 重庆康视美科技有限公司 一种治疗近视的生物制剂及其制备方法、使用方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002247A1 (en) * 1990-08-01 1992-02-20 Chiron Ophthalmics, Inc. Method for treating corneal endothelial wounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002247A1 (en) * 1990-08-01 1992-02-20 Chiron Ophthalmics, Inc. Method for treating corneal endothelial wounds

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CONNOR T.B. ET AL.: "Correlation of Fibrosis and Transforming Growth Factor-beta Type 2 Levels in the Eye", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 85, no. 5, pages 1661 - 1666, XP002047092, DOI: doi:10.1172/JCI114065 *
JAMPEL H D ET AL: "TRANSFORMING GROWTH FACTOR -BETA IN HUMAN AQUEOUS HUMOR.", CURR EYE RES 9 (10). 1990. 963-970. *
See also references of WO9401124A1 *
TRIPATHI R C ET AL: "Role of Growth Factors in the Uveal Tract of the Eye as Targeted to the Development of Nw Drugs", DRUG DEV RES 23(1). 1991. 1-25. *

Also Published As

Publication number Publication date
AU4668193A (en) 1994-01-31
CA2138644A1 (en) 1994-01-20
JPH08502033A (ja) 1996-03-05
WO1994001124A1 (en) 1994-01-20
EP0651650A1 (de) 1995-05-10

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