EP0666752A4 - Therapeutische mikroemulsionen. - Google Patents

Therapeutische mikroemulsionen.

Info

Publication number: EP0666752A4
Authority: EP; European Patent Office
Prior art keywords: microemulsions; therapeutic; therapeutic microemulsions
Prior art date: 1992-10-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP93923933A

Other languages

English (en)

French (fr)

Other versions

EP0666752A1 (de

Inventor

Panayiotis Peri Constantinides

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-10-16

Filing date

1993-10-15

Publication date

1996-09-11

1993-10-15 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

1995-08-16 Publication of EP0666752A1 publication Critical patent/EP0666752A1/de

1996-09-11 Publication of EP0666752A4 publication Critical patent/EP0666752A4/de

Status Withdrawn legal-status Critical Current

Links

239000004530 micro-emulsion Substances 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Zoology (AREA)
Dispersion Chemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biomedical Technology (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EP93923933A 1992-10-16 1993-10-15 Therapeutische mikroemulsionen. Withdrawn EP0666752A4 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US96295792A	1992-10-16	1992-10-16
US962957		1992-10-16
PCT/US1993/009963 WO1994008605A1 (en)	1992-10-16	1993-10-15	Therapeutic microemulsions

Publications (2)

Publication Number	Publication Date
EP0666752A1 EP0666752A1 (de)	1995-08-16
EP0666752A4 true EP0666752A4 (de)	1996-09-11

Family

ID=25506555

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP93923933A Withdrawn EP0666752A4 (de)	1992-10-16	1993-10-15	Therapeutische mikroemulsionen.

Country Status (3)

Country	Link
EP (1)	EP0666752A4 (de)
JP (1)	JPH08502492A (de)
WO (1)	WO1994008605A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69229779T2 (de) *	1991-04-19	1999-12-23	Lds Technologies, Inc.	Konvertierbare mikroemulsionsverbindungen
US5688761A (en) *	1991-04-19	1997-11-18	Lds Technologies, Inc.	Convertible microemulsion formulations
US6395494B1 (en)	1993-05-13	2002-05-28	Neorx Corporation	Method to determine TGF-β
US5981568A (en)	1993-01-28	1999-11-09	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
ATE223231T1 (de) *	1993-04-19	2002-09-15	Inst Advanced Skin Res Inc	Mikroemulsionszubereitung enthaltend eine schwer absorbierbare substanz
DE69435137D1 (de) *	1993-05-13	2008-10-16	Poniard Pharmaceuticals Inc	Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind
DE69535127T2 (de) *	1994-03-18	2007-02-15	Supernus Pharmaceuticals, Inc.	Emulgierte arzneistoffabgabesysteme
HU215966B (hu) *	1994-11-21	1999-07-28	BIOGAL Gyógyszergyár Rt.	Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
EP0811072A1 (de)	1995-02-25	1997-12-10	Imperial Cancer Research Technology Limited	Transgene tiere als modell für psoriasis
US5824638A (en) *	1995-05-22	1998-10-20	Shire Laboratories, Inc.	Oral insulin delivery
US6008228A (en) *	1995-06-06	1999-12-28	Hoffman-La Roche Inc.	Pharmaceutical compositions containing proteinase inhibitors
US5734770A (en) *	1995-06-29	1998-03-31	Minnesota Mining And Manufacturing Company	Cleave and bevel fiber optic connector
US5660858A (en) *	1996-04-03	1997-08-26	Research Triangle Pharmaceuticals	Cyclosporin emulsions
GB9613858D0 (en)	1996-07-02	1996-09-04	Cortecs Ltd	Hydrophobic preparations
WO1998022089A1 (en) *	1996-11-22	1998-05-28	Pharmacia & Upjohn Ab	Pharmaceutical composition based on a lipid matrix system
JP2001521503A (ja)	1997-03-31	2001-11-06	ネオルックスコーポレイション	血管平滑筋細胞の治療的阻害物質
US6284268B1 (en)	1997-12-10	2001-09-04	Cyclosporine Therapeutics Limited	Pharmaceutical compositions containing an omega-3 fatty acid oil
US6979456B1 (en)	1998-04-01	2005-12-27	Jagotec Ag	Anticancer compositions
WO1999053941A1 (fr) *	1998-04-15	1999-10-28	Shionogi & Co., Ltd.	Preparations orales contenant des derives de trh
DE10024451A1 (de) *	2000-05-18	2001-11-29	Asta Medica Ag	Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
US20020155084A1 (en) *	2000-06-02	2002-10-24	The Regents Of The University Of The Michigan	Nanoemulsion formulations
CN1160122C (zh)	2001-04-20	2004-08-04	清华大学	一种制备口服胰岛素油相制剂的方法
US6613083B2 (en)	2001-05-02	2003-09-02	Eckhard Alt	Stent device and method
EP1435910B9 (de)	2001-10-19	2010-02-03	Isotechnika Inc.	Neue cyclosporin-analoge mikroemulsionsvorkonzentrate
MXPA04005783A (es) *	2001-12-14	2004-09-13	Jagotec Ag	Formulacion farmaceutica que comprende ciclosporina y uso de la misma.
PE20050596A1 (es) *	2003-12-19	2005-10-18	Novartis Ag	Microemulsion que comprende un inhibidor renina
CA2560613C (en)	2004-03-22	2015-11-24	Solvay Pharmaceuticals Gmbh	Oral pharmaceutical compositions of lipase-containing products, in particular of pancreatin, containing surfactants
US9743680B2 (en) *	2005-10-14	2017-08-29	Wild Flavors, Inc.	Microemulsions for use in food and beverage products
EP1961412A1 (de) *	2006-12-27	2008-08-27	LEK Pharmaceuticals D.D.	Selbstmikroemulgierende Arzneimittelabgabesysteme
EP2514406A1 (de) *	2007-06-01	2012-10-24	Novo Nordisk A/S	Spontan dispergierbare Vorkonzentrate mit einem Peptidwirkstoff in einem festen oder halbfesten Träger
HUE032284T2 (en)	2008-03-18	2017-09-28	Novo Nordisk As	Protease-stabilized, acylated insulin analogues
GB201107630D0 (en) *	2011-05-06	2011-06-22	Proxima Concepts Ltd	Microemulsions
EP2836508B1 (de)	2012-04-11	2016-06-29	Novo Nordisk A/S	Insulinformulierungen
ES2886837T3 (es)	2016-12-16	2021-12-21	Novo Nordisk As	Composiciones farmacéuticas que contienen insulina
KR101991661B1 (ko) *	2017-03-02	2019-06-21	대화제약 주식회사	자나미비르를 포함하는 안정한 약제학적 조성물
WO2018159941A1 (ko) *	2017-03-02	2018-09-07	대화제약 주식회사	자나미비르를 포함하는 안정한 약제학적 조성물

Citations (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4146499A (en) *	1976-09-18	1979-03-27	Rosano Henri L	Method for preparing microemulsions
EP0278660A1 (de) *	1987-02-03	1988-08-17	Stiefel Laboratories (Ireland) Limited	Mikroemulsionen
EP0387647A2 (de) *	1989-03-13	1990-09-19	Desitin Arzneimittel GmbH	Hochdisperse pharmazeutische Zusammensetzung
WO1991018669A1 (en) *	1990-06-08	1991-12-12	Affinity Biotech, Inc.	Process for preparing microemulsion
WO1992018147A1 (en) *	1991-04-19	1992-10-29	Affinity Biotech, Inc.	Convertible microemulsion formulations
WO1993002664A1 (en) *	1991-07-26	1993-02-18	Smithkline Beecham Corporation	W/o microemulsions
WO1993002665A1 (en) *	1991-07-26	1993-02-18	Smithkline Beecham Corporation	W/o microemulsions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5110606A (en) *	1990-11-13	1992-05-05	Affinity Biotech, Inc.	Non-aqueous microemulsions for drug delivery

1993
- 1993-10-15 EP EP93923933A patent/EP0666752A4/de not_active Withdrawn
- 1993-10-15 JP JP6510336A patent/JPH08502492A/ja active Pending
- 1993-10-15 WO PCT/US1993/009963 patent/WO1994008605A1/en not_active Ceased

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4146499A (en) *	1976-09-18	1979-03-27	Rosano Henri L	Method for preparing microemulsions
EP0278660A1 (de) *	1987-02-03	1988-08-17	Stiefel Laboratories (Ireland) Limited	Mikroemulsionen
EP0387647A2 (de) *	1989-03-13	1990-09-19	Desitin Arzneimittel GmbH	Hochdisperse pharmazeutische Zusammensetzung
WO1991018669A1 (en) *	1990-06-08	1991-12-12	Affinity Biotech, Inc.	Process for preparing microemulsion
WO1992018147A1 (en) *	1991-04-19	1992-10-29	Affinity Biotech, Inc.	Convertible microemulsion formulations
WO1993002664A1 (en) *	1991-07-26	1993-02-18	Smithkline Beecham Corporation	W/o microemulsions
WO1993002665A1 (en) *	1991-07-26	1993-02-18	Smithkline Beecham Corporation	W/o microemulsions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9408605A1 *

Also Published As

Publication number	Publication date
EP0666752A1 (de)	1995-08-16
WO1994008605A1 (en)	1994-04-28
JPH08502492A (ja)	1996-03-19

Legal Events

Date	Code	Title	Description
1995-06-30	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-08-16	17P	Request for examination filed	Effective date: 19950510
1995-08-16	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): BE CH DE FR GB IT LI NL
1996-01-10	RHK1	Main classification (correction)	Ipc: A61K 38/00
1996-09-04	RHK1	Main classification (correction)	Ipc: A61K 37/00
1996-09-11	A4	Supplementary search report drawn up and despatched	Effective date: 19960729
1996-09-11	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): BE CH DE FR GB IT LI NL
1998-11-11	17Q	First examination report despatched	Effective date: 19980925
1999-06-18	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
1999-08-04	18D	Application deemed to be withdrawn	Effective date: 19990206

Publication	Publication Date	Title
EP0597463A3 (en)	1996-11-06	Thermotherapiesonde.
EP0580285A3 (de)	1995-05-03	Selbsttätige Wiedereinschalter.
GR3025363T3 (en)	1998-02-27	Medicaments.
GR3022484T3 (en)	1997-05-31	Osteosynthesis aid.
AU116235S (en)	1993-02-03	Chair
ZA927562B (en)	1993-04-14	Medicament.
EP0676156A4 (de)	1996-06-19	Stuhl.
EP0684834A4 (de)	1996-09-25	Mikroemulsionen, die therapeutische peptide enthalten.
EP0684833A4 (de)	1996-09-11	Mikroemulsionen mit therapeutischen peptiden.
ZA926220B (en)	1994-01-25	Microemulsions
EP0646342A3 (de)	1996-06-05	Stuhl.
EP0599191A3 (de)	1995-02-08	Motordrehzahlregler-Schaltkreis.
EP0599077A3 (de)	1994-11-23	Anti-metastatischer Impfstoff.
AU116238S (en)	1993-02-03	Chair
PH31659A (en)	1999-01-12	Therapeutic nucleotides.
ZA935828B (en)	1994-03-10	New insobutyl-substituted methanesulphonyl-quinolyl-methoxyphenyl-cycloalkylacetamides.
EP0624089A4 (en)	1994-12-14	Methods.
ZA921092B (en)	1992-09-30	Microemulsions
EP0662782A4 (de)	1995-10-25	Pp14-basierte therapie.
ZA939564B (en)	1994-08-15	Vaccines.
EP0681480A4 (de)	1997-06-25	Recognin vakzine.
ZA929916B (en)	1993-06-23	Therapeutic agents.
ZA93236B (en)	1993-08-16	Babesial rhoptry antigens.
EG19223A (en)	1994-09-29	Therapeutic agents.
ZA933136B (en)	1994-01-05	Therapeutic alcohols.