EP0674528A4 - Cyclodextrine et systeme de liberation de medicament a base de polymere. - Google Patents

Cyclodextrine et systeme de liberation de medicament a base de polymere.

Info

Publication number
EP0674528A4
EP0674528A4 EP94902482A EP94902482A EP0674528A4 EP 0674528 A4 EP0674528 A4 EP 0674528A4 EP 94902482 A EP94902482 A EP 94902482A EP 94902482 A EP94902482 A EP 94902482A EP 0674528 A4 EP0674528 A4 EP 0674528A4
Authority
EP
European Patent Office
Prior art keywords
cyclodextrin
delivery system
drug delivery
polymer based
based drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94902482A
Other languages
German (de)
English (en)
Other versions
EP0674528A1 (fr
Inventor
Sheng-Wan Tsao
Lyle M Bowman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Pharmaceutical Industries Inc
Original Assignee
Insite Vision Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/984,445 external-priority patent/US5332582A/en
Application filed by Insite Vision Inc filed Critical Insite Vision Inc
Publication of EP0674528A1 publication Critical patent/EP0674528A1/fr
Publication of EP0674528A4 publication Critical patent/EP0674528A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medical Informatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
EP94902482A 1992-12-02 1993-12-01 Cyclodextrine et systeme de liberation de medicament a base de polymere. Withdrawn EP0674528A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US07/984,445 US5332582A (en) 1990-06-12 1992-12-02 Stabilization of aminosteroids for topical ophthalmic and other applications
US984445 1992-12-02
US15516793A 1993-11-19 1993-11-19
US155167 1993-11-19
PCT/US1993/011651 WO1994012217A1 (fr) 1992-12-02 1993-12-01 Cyclodextrine et systeme de liberation de medicament a base de polymere

Publications (2)

Publication Number Publication Date
EP0674528A1 EP0674528A1 (fr) 1995-10-04
EP0674528A4 true EP0674528A4 (fr) 1996-06-26

Family

ID=26852057

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94902482A Withdrawn EP0674528A4 (fr) 1992-12-02 1993-12-01 Cyclodextrine et systeme de liberation de medicament a base de polymere.

Country Status (6)

Country Link
EP (1) EP0674528A4 (fr)
JP (1) JPH08503951A (fr)
CN (1) CN1103316A (fr)
AU (1) AU672862B2 (fr)
CA (1) CA2150554A1 (fr)
WO (1) WO1994012217A1 (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW434023B (en) * 1995-09-18 2001-05-16 Novartis Ag Preserved ophthalmic composition
JP3940209B2 (ja) 1996-11-14 2007-07-04 株式会社資生堂 可溶化化粧料
GB9711643D0 (en) * 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
US6656456B2 (en) 1998-11-23 2003-12-02 The Procter & Gamble Company Skin deodorizing compositions
WO2000030599A1 (fr) * 1998-11-23 2000-06-02 The Procter & Gamble Company Compositions de desodorisation et d'assainissement de la peau
CA2726789A1 (fr) 2000-02-05 2001-11-08 Theravance, Inc. Preparations antibiotiques a base de glycopeptides contenant des cyclodextrines
EP1938799B1 (fr) * 2000-03-10 2013-05-08 Insite Vision Incorporated Compositions pour le traitement et la prévention de troubles ophtalmiques du segment postérieur et leur utilisation
AU2001259298A1 (en) 2000-05-02 2001-11-12 Advanced Medicine, Inc. Polyacid glycopeptide derivatives
ES2302733T3 (es) 2000-06-22 2008-08-01 Theravance, Inc. Derivados carboxi-sacaridos de glucopeptido.
WO2001098329A1 (fr) 2000-06-22 2001-12-27 Theravance, Inc. Derives polyhydroxy de glycopeptides
US6872804B2 (en) 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
UA75083C2 (uk) 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
AU2001288120A1 (en) * 2000-09-26 2002-04-08 Kyorin Pharmaceutical Co. Ltd. Liquid prednisolone sodium phosphate preparation
JP2004529178A (ja) * 2001-05-11 2004-09-24 パシフィック・ファーマシューティカルズ・リミテッド 味遮蔽医薬組成物
EP1621199B8 (fr) * 2003-04-18 2011-01-19 Advanced Medicine Research Institute Remedes a des affections, a usage ophtalmique
US6933289B2 (en) 2003-07-01 2005-08-23 Allergan, Inc. Inhibition of irritating side effects associated with use of a topical ophthalmic medication
WO2006040839A1 (fr) * 2004-10-15 2006-04-20 Advanced Medicine Research Institute Gouttes oculaires et trousses de traitement de maladies oculaires
JP2007177149A (ja) * 2005-12-28 2007-07-12 Shield Lab:Kk チオクト酸又はジヒドロリポ酸と分岐鎖シクロデキストリンとの包接化合物
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US20100311738A1 (en) * 2007-12-21 2010-12-09 Aop Orphan Pharmaceuticals Ag Pharmaceutical Composition For The Parenteral Administration Of Ultrashort-Effective Beta-Adrenoreceptor Antagonists
US10201548B2 (en) 2009-03-06 2019-02-12 Sun Pharma Global Fze Methods for treating ocular inflammatory diseases
US10980818B2 (en) 2009-03-06 2021-04-20 Sun Pharma Global Fze Methods for treating ocular inflammatory diseases
JP5996544B2 (ja) 2010-10-15 2016-09-21 クリアサイド・バイオメディカル・インコーポレーテッドClearside Biomedical Incorporated 眼球アクセス用装置
MX373894B (es) 2012-11-08 2020-07-09 Clearside Biomedical Inc Métodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos.
WO2014127018A1 (fr) * 2013-02-12 2014-08-21 Ys Pharmtech Formulations d'épinéphrine pour produits médicinaux
BR112015027762A2 (pt) 2013-05-03 2017-08-29 Clearside Biomedical Inc Aparelho e métodos para injeção ocular
US10010447B2 (en) 2013-12-18 2018-07-03 Novartis Ag Systems and methods for subretinal delivery of therapeutic agents
CN103990137A (zh) * 2014-04-30 2014-08-20 福建融和药业有限公司 一种粘膜粘附性聚合物眼用药物的缓释剂
US10390901B2 (en) 2016-02-10 2019-08-27 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
EP3452165A1 (fr) 2016-05-02 2019-03-13 Clearside Biomedical, Inc. Systèmes et méthodes pour l'administration de médicaments par voie ophtalmique
IL305537B2 (en) 2016-08-12 2025-02-01 Clearside Biomedical Inc Devices and methods for adjusting the insertion depth of a needle for administering a drug
US12090294B2 (en) 2017-05-02 2024-09-17 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
CN109136177B (zh) * 2018-08-03 2021-09-17 湖南大学 一种地塞米松缓释体系以及一种成骨分化诱导液和应用
RU2740287C1 (ru) * 2019-08-30 2021-01-12 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) 3д-матриксная структура для доставки лекарственных препаратов
CN115380899A (zh) * 2022-08-30 2022-11-25 陕西科技大学 一种凝胶型腐植酸缓释农药及其制备方法
WO2024097388A1 (fr) * 2022-11-03 2024-05-10 Arizona Board Of Regents On Behalf Of The University Of Arizona Systèmes et méthodes de surveillance du métabolisme des acides gras

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300526A2 (fr) * 1987-07-01 1989-01-25 Janssen Pharmaceutica N.V. Compositions pharmaceutiques antivirales contenant des cyclodextrines
EP0399716A1 (fr) * 1989-05-24 1990-11-28 Innovet, Inc. Composition hypoallergénique stéroide à activité anesthésiante/hypnotique
EP0463653A1 (fr) * 1990-06-07 1992-01-02 PHARMACIA S.p.A. Formulations galéniques contenant des cyclodextrines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4383992A (en) * 1982-02-08 1983-05-17 Lipari John M Water-soluble steroid compounds
US5002935A (en) * 1987-12-30 1991-03-26 University Of Florida Improvements in redox systems for brain-targeted drug delivery
IE63392B1 (en) * 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300526A2 (fr) * 1987-07-01 1989-01-25 Janssen Pharmaceutica N.V. Compositions pharmaceutiques antivirales contenant des cyclodextrines
EP0399716A1 (fr) * 1989-05-24 1990-11-28 Innovet, Inc. Composition hypoallergénique stéroide à activité anesthésiante/hypnotique
EP0463653A1 (fr) * 1990-06-07 1992-01-02 PHARMACIA S.p.A. Formulations galéniques contenant des cyclodextrines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9412217A1 *

Also Published As

Publication number Publication date
WO1994012217A1 (fr) 1994-06-09
CN1103316A (zh) 1995-06-07
EP0674528A1 (fr) 1995-10-04
JPH08503951A (ja) 1996-04-30
CA2150554A1 (fr) 1994-06-09
AU672862B2 (en) 1996-10-17
AU5684194A (en) 1994-06-22

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19950529

AK Designated contracting states

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18D Application deemed to be withdrawn

Effective date: 19980813