EP0684833A4 - Microemulsions comprising therapeutic peptides. - Google Patents

Microemulsions comprising therapeutic peptides.

Info

Publication number
EP0684833A4
EP0684833A4 EP94909654A EP94909654A EP0684833A4 EP 0684833 A4 EP0684833 A4 EP 0684833A4 EP 94909654 A EP94909654 A EP 94909654A EP 94909654 A EP94909654 A EP 94909654A EP 0684833 A4 EP0684833 A4 EP 0684833A4
Authority
EP
European Patent Office
Prior art keywords
microemulsions
therapeutic peptides
peptides
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94909654A
Other languages
German (de)
French (fr)
Other versions
EP0684833A1 (en
Inventor
Panayiotis Peri Constantinides
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0684833A1 publication Critical patent/EP0684833A1/en
Publication of EP0684833A4 publication Critical patent/EP0684833A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/25Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP94909654A 1993-02-17 1994-02-17 Microemulsions comprising therapeutic peptides. Withdrawn EP0684833A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1860993A 1993-02-17 1993-02-17
US18609 1993-02-17
PCT/US1994/001678 WO1994019001A1 (en) 1993-02-17 1994-02-17 Microemulsions comprising therapeutic peptides

Publications (2)

Publication Number Publication Date
EP0684833A1 EP0684833A1 (en) 1995-12-06
EP0684833A4 true EP0684833A4 (en) 1996-09-11

Family

ID=21788831

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94909654A Withdrawn EP0684833A4 (en) 1993-02-17 1994-02-17 Microemulsions comprising therapeutic peptides.

Country Status (3)

Country Link
EP (1) EP0684833A4 (en)
JP (1) JPH08507066A (en)
WO (1) WO1994019001A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
CA2160681A1 (en) * 1993-04-19 1994-10-27 Masao Takahashi Microemulsion preparation containing a slightly absorbable substance
JPH09510182A (en) * 1993-11-17 1997-10-14 エルディーエス・テクノロジーズ・インコーポレーテッド Encapsulated transparent liquid for drug delivery
WO1998043618A2 (en) 1997-03-31 1998-10-08 Neorx Corporation Use of cytoskeletal inhibitors for the prevention of restenosis
DE19716953B4 (en) * 1997-04-22 2006-02-09 Forschungszentrum Jülich GmbH Process for the remediation of contaminated soil and bicontinuous microemulsion
DE10013796A1 (en) * 2000-03-20 2001-09-27 Kaercher Gmbh & Co Alfred Decontamination composition useful for treating surfaces contaminated with chemical warfare agents comprises an active agent, a neutral salt, an emulsifier and a solvent derived from natural fatty acids
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US20110144010A1 (en) * 2007-06-01 2011-06-16 Novo Nordisk A/S Spontaneously Dispersible Preconcentrates Including a Peptide Drug in a Solid or Semisolid Carrier
HUE032284T2 (en) 2008-03-18 2017-09-28 Novo Nordisk As Protease stabilized, acylated insulin analogues
CN104364260B (en) 2012-04-11 2017-02-22 诺和诺德股份有限公司 insulin formulations
BR112018069631B1 (en) * 2016-04-21 2021-10-26 Unilever Ip Holdings B.V. NANOEMULSION COMPOSITION, PERSONAL CARE COMPOSITION AND PROCESS TO PREPARE A NANOEMULSION
EA037099B1 (en) * 2016-04-21 2021-02-05 Юнилевер Н.В. Process for making a nanoemulsion composition of oils
US11744783B2 (en) 2016-04-21 2023-09-05 Conopco, Inc. Nanoemulsions comprising fatty acid and n-acyl derivatives of amino acid salt
PE20210857A1 (en) 2016-12-16 2021-05-18 Novo Nordisk As PHARMACEUTICAL COMPOSITIONS CONTAINING INSULIN
CN107496912B (en) * 2017-04-14 2021-06-29 郑振宜 An antigen-presenting signal ensemble of hepatitis B virus antigen peptide combined with liver cancer cell antigen information and its application
CN109010117B (en) * 2018-07-10 2021-05-25 山西医科大学 Micro-emulsion gel lip-protecting gel with moisturizing and moisturizing effects and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
EP0278660A1 (en) * 1987-02-03 1988-08-17 Stiefel Laboratories (Ireland) Limited Microemulsions
EP0387647A2 (en) * 1989-03-13 1990-09-19 Desitin Arzneimittel GmbH High-dispersion pharmaceutical composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110606A (en) * 1990-11-13 1992-05-05 Affinity Biotech, Inc. Non-aqueous microemulsions for drug delivery

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
EP0278660A1 (en) * 1987-02-03 1988-08-17 Stiefel Laboratories (Ireland) Limited Microemulsions
EP0387647A2 (en) * 1989-03-13 1990-09-19 Desitin Arzneimittel GmbH High-dispersion pharmaceutical composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9419001A1 *

Also Published As

Publication number Publication date
JPH08507066A (en) 1996-07-30
WO1994019001A1 (en) 1994-09-01
EP0684833A1 (en) 1995-12-06

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19950914

AK Designated contracting states

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Designated state(s): BE CH DE FR GB IT LI NL

A4 Supplementary search report drawn up and despatched

Effective date: 19960729

AK Designated contracting states

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Designated state(s): BE CH DE FR GB IT LI NL

RIN1 Information on inventor provided before grant (corrected)

Inventor name: CONSTANTINIDES, PANAYIOTIS PERICLEOUS

17Q First examination report despatched

Effective date: 19990218

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19990629