EP0703157A1 - Emballage du type blister - Google Patents
Emballage du type blister Download PDFInfo
- Publication number
- EP0703157A1 EP0703157A1 EP95810514A EP95810514A EP0703157A1 EP 0703157 A1 EP0703157 A1 EP 0703157A1 EP 95810514 A EP95810514 A EP 95810514A EP 95810514 A EP95810514 A EP 95810514A EP 0703157 A1 EP0703157 A1 EP 0703157A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- packaging material
- symmetry
- depressions
- sheet
- line
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000005022 packaging material Substances 0.000 claims abstract description 87
- 239000000463 material Substances 0.000 claims description 33
- 239000011888 foil Substances 0.000 claims description 26
- 238000007789 sealing Methods 0.000 claims description 26
- 238000000034 method Methods 0.000 claims description 15
- 229910052751 metal Inorganic materials 0.000 claims description 13
- 239000002184 metal Substances 0.000 claims description 13
- 229910052782 aluminium Inorganic materials 0.000 claims description 12
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 12
- 239000002775 capsule Substances 0.000 claims description 12
- 238000005520 cutting process Methods 0.000 claims description 12
- 239000004952 Polyamide Substances 0.000 claims description 10
- 229920002647 polyamide Polymers 0.000 claims description 10
- 238000007373 indentation Methods 0.000 claims description 9
- 238000004519 manufacturing process Methods 0.000 claims description 9
- 239000007903 gelatin capsule Substances 0.000 claims description 7
- 239000004615 ingredient Substances 0.000 claims description 7
- 239000008298 dragée Substances 0.000 claims description 6
- 229920000915 polyvinyl chloride Polymers 0.000 claims description 5
- 239000003826 tablet Substances 0.000 claims description 5
- 239000006187 pill Substances 0.000 claims description 4
- 239000004800 polyvinyl chloride Substances 0.000 claims description 4
- 235000013305 food Nutrition 0.000 claims description 3
- 238000004026 adhesive bonding Methods 0.000 claims 1
- 239000010410 layer Substances 0.000 description 29
- 239000000853 adhesive Substances 0.000 description 10
- 230000001070 adhesive effect Effects 0.000 description 10
- -1 for example Substances 0.000 description 9
- 230000003313 weakening effect Effects 0.000 description 9
- 229920006255 plastic film Polymers 0.000 description 8
- 239000002985 plastic film Substances 0.000 description 8
- 238000004080 punching Methods 0.000 description 8
- 238000004806 packaging method and process Methods 0.000 description 5
- 229920003023 plastic Polymers 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920002635 polyurethane Polymers 0.000 description 4
- 239000004814 polyurethane Substances 0.000 description 4
- 239000004698 Polyethylene Substances 0.000 description 3
- 239000004743 Polypropylene Substances 0.000 description 3
- 239000013067 intermediate product Substances 0.000 description 3
- 238000003475 lamination Methods 0.000 description 3
- 229920000573 polyethylene Polymers 0.000 description 3
- 229920000098 polyolefin Polymers 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 239000012173 sealing wax Substances 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 239000003822 epoxy resin Substances 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 239000002650 laminated plastic Substances 0.000 description 2
- 239000012939 laminating adhesive Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 229920000647 polyepoxide Polymers 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 210000002023 somite Anatomy 0.000 description 2
- 235000013599 spices Nutrition 0.000 description 2
- 239000012815 thermoplastic material Substances 0.000 description 2
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- 239000004821 Contact adhesive Substances 0.000 description 1
- 239000004593 Epoxy Substances 0.000 description 1
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 235000011941 Tilia x europaea Nutrition 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000002318 adhesion promoter Substances 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000003851 corona treatment Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000004922 lacquer Substances 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 239000010445 mica Substances 0.000 description 1
- 229910052618 mica group Inorganic materials 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229910000510 noble metal Inorganic materials 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 238000009832 plasma treatment Methods 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000010345 tape casting Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/321—Both sheets being recessed
- B65D75/323—Both sheets being recessed and forming several compartments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B9/00—Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
- B65B9/02—Enclosing successive articles, or quantities of material between opposed webs
- B65B9/04—Enclosing successive articles, or quantities of material between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material
- B65B9/045—Enclosing successive articles, or quantities of material between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material for single articles, e.g. tablets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
- B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/52—Details
- B65D75/527—Tear-lines for separating a package into individual packages
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2585/00—Containers, packaging elements or packages specially adapted for particular articles or materials
- B65D2585/56—Containers, packaging elements or packages specially adapted for particular articles or materials for medicinal tablets or pills
Definitions
- the present invention relates to a blister pack consisting of a base part and a cover part made of sheet-like packaging material, a method for producing blister packs and their use.
- So-called blister packs or blister packs are known.
- plastic films or plastic laminates or plastic laminates containing a metal foil are deepened in such a way that a plurality of depressions or cells are formed. Shoulders form between the individual wells. The shoulders run completely around each depression and form a flat shoulder surface. The materials prepared in this way form the base part of a blister pack.
- the bottom parts can be filled with the ingredients. Is known as an ingredient e.g. Pour tablets, capsules, dragees, etc. from the pharmaceutical sector, individually or in pairs, into each well.
- the bottom part is then closed, usually with a metal foil, such as an aluminum foil or a film composite, which contains, for example, a sealing layer and a metal foil, by sealing over the sealing layer.
- the depression is pressed in from the bottom part side and the tablet or capsule presses from the inside against the metal foil-containing lid over the depression. Due to the inelasticity of the lid material, the lid bursts and the contents are released.
- the object of the present invention is to propose a blister pack which, in particular in the case of relatively large ingredients, such as, for example, Capsules with pharmaceutical preparations, makes it possible to keep the height of the wells relatively small and thus simplify the depths. Furthermore, smaller shoulder areas should be provided and nevertheless a secure seal between the base part and the cover part should be achieved.
- the bottom part has permanently molded-in depressions which are surrounded by shoulders
- the cover part has permanently molded-in depressions which are surrounded by shoulders and with respect to the bottom part and cover part the openings of the depressions lie on a plane of symmetry and the bottom part and lid part are connected to one another in whole or in part over their shoulders in the area of the plane of symmetry, and form the depressions of the bottom part and lid part symmetrically with respect to the plane of symmetry, and the contents are located in the courtyards.
- a blister pack may have a series of indentations permanently molded or two or more rows of such recesses, the rows of the recesses being parallel to one another.
- the courtyards based on the length of a blister pack, can be arranged at the same height or offset from one another.
- the shoulders expediently form a flat shoulder surface.
- the blister pack is usually a section or die cut from an endless sheet of packaging material.
- Blister packs which have been produced by forming a single packaging material strip or two packaging material strips of the same or different packaging material are expedient, it being possible in particular for the depressions to be formed by means of a single molding tool.
- the cover material can be folded over the base material.
- the indentations, both for the base part and for the lid part, are in particular permanently (permanently) and in their final dimensions molded into the packaging material and the indentations of the base part are then available for filling with the content as a receiving tray.
- the lid part with the molded-in depressions is brought over the base part and the two parts are mutually fixed over the shoulders, the content being in the courtyard or cavity thus created, without the content causing, for example, further deformation of the packaging material.
- a blister pack is preferred in which one of the longitudinal side edges represents a web-shaped packaging material folded along a line of symmetry.
- the blister packs can be an intermediate product and a final blister pack can be a die cut from this intermediate product.
- the intermediate product can be changed by further processing, for example to remove the folded side edge or to shape the blister pack in its circumferential shape, by cutting or punching.
- a blister pack between the individual courtyards - in the area of the shoulders - can have weaknesses or perforations which make it possible to separate individual portions.
- each individual portion can have a weakening, an incision, a notch or the like, which make it possible to destroy the blister pack to such an extent that the courtyard is exposed and the content can be extracted.
- punch holes can be made, for example, in the region of the overlaps of the longitudinal and transverse perforations. The punch holes then form tear tabs for the individual portions.
- the blister pack according to the invention is manufactured from sheet-like packaging material.
- the packaging material can for example contain a metal layer and expediently a metal foil.
- the metal foil can, for example, be 8 to 50 ⁇ m thick and preferably consist of aluminum or its alloy, or it can be an iron or steel foil or, in special cases, a noble metal foil.
- the sheet-like packaging material can be, for example, a metal foil with a sealing layer, for example a sealing wax or a sealing foil.
- the sealing wax can have a thickness of, for example, 2 to 10 ⁇ m or a square meter weight of 0.1 to 10 g / m.
- the sealing layer can contain, for example, polyolefins, such as polyethylene or polypropylene or polyester.
- the sheet-like packaging material can also be a plastic layer and in particular a plastic film or can be a laminate of plastic layers and in particular plastic films, or can be a laminate of plastic layers and metal layers and in particular plastic films and metal foils.
- Typical plastic films are, for example, films made of thermoplastic materials, such as polyamides, polyvinyl chlorides, polyvinylidene chlorides, polyesters, such as polyethylene terephthalates or polyolefins, such as polyethylene or polypropylenes.
- the thickness of such plastic films can be, for example, from 12 to 50 ⁇ m.
- laminates composed of 2 or more plastic films of the thermoplastic materials mentioned are preferred.
- the thickness of the individual layers can again be 12 to 50 ⁇ m.
- the individual layers resp. Films can be mutually fixed, for example, by adhesives and / or adhesion promoters.
- the laminates can be produced as described above, for example by extrusion, coextrusion, lamination or extrusion lamination.
- the individual layers can also be subjected to a plasma or corona treatment, for example.
- a sealing layer is in particular on that Side of the films or laminates attached, which form the shoulders on the blister pack produced therefrom and which surrounds the openings of the recess.
- a packaging material which results in a suitable base material and particularly preferred cover material contains a layer with a thickness of 12 to 50 ⁇ m, preferably 20 to 30 ⁇ m, made of a film made of oriented polyamide, and a layer with a thickness of 16 to 50 ⁇ m, preferably 20 up to 45 ⁇ m, aluminum foil.
- This material on the other, i.e. free side of the aluminum foil e.g. have a sealing layer, expediently a hot sealing lacquer in a thickness of 5 to 15 ⁇ m, expediently 5 to 9 ⁇ m.
- a laminating adhesive layer e.g. in a thickness of 3 to 5 ⁇ m, e.g. a polyurethane adhesive and a primer layer, e.g. in a thickness of 1.5 to 3 ⁇ m, e.g. made of epoxy resin.
- the layer of oriented polyamide serves as a stretching agent in the deepening process and is advantageously placed on the outside in the finished blister pack.
- the sealing layer is accordingly on the inside and thus against the floor or. Cover part.
- a packaging material which produces a particularly preferred base part material and suitable cover part material contains a layer with a thickness of 12 to 50 ⁇ m, preferably 20 to 30 ⁇ m, made of a film of oriented polyamide, and a layer with a thickness of 16 to 50 ⁇ m, preferably 20 up to 45 ⁇ m, in the form of an aluminum foil.
- this material contains free side of the aluminum foil e.g. a 30 to 80 microns, preferably 50 to 70 microns thick film made of polyvinyl chloride.
- a lamination adhesive layer e.g. in a thickness of 3 to 5 ⁇ m, e.g. a polyurethane adhesive and, or only, e.g. 1.5 to 3 ⁇ m thick primer layer, e.g. made of epoxy resin.
- a layer with a thickness of 3 to 5 ⁇ m of a laminating adhesive for example a polyurethane adhesive, can be arranged between the aluminum foil and the PVC foil.
- Blister packs made of the particularly preferred base part material and the particularly preferred cover part material, as described above, are very particularly preferred.
- the packaging materials used expediently have such a degree of rigidity that they are rolled into supply rolls and, for example, also in machine processes can be unrolled again and guided through the corresponding processing machines. After the recesses have been made, due to the stiffening effect of the recesses, there are essentially dimensionally stable base parts and cover parts.
- the shape and height of the depressions in the base part and cover part can e.g. be symmetrical, i.e. the lid part forms the mirror image of the bottom part.
- Each depression in the base part has a mirror-image identical depression in the cover part and the two depressions together form a symmetrical courtyard.
- the base part and cover part preferably have depressions of symmetrical height. However, the shape and position of the opening of each depression in the base part and the associated opening of each depression in the cover part are the same and lie congruently one above the other.
- a depression in the base part and a depression in the cover part together form a courtyard or a cavity with a clear height x.
- the height x of each courtyard can be 1/10 to 9/10, expediently 5/10 to 9/10, from the depression in the base part and 9/10 to 1/10, expediently 5/10 to 1/10, from the Be formed in the lid part.
- the proportion of the height of the depression in the base part is 6/10 to 9/10 and in particular 7/10 to 9/10, the clear height x.
- the depressions in the bottom part expediently have the shape of a half-shell with a turning angle of 30 to 60 °, preferably 45 °.
- the proportion of the height of the depression in the cover part is preferably 4/10 to 1/10 and in particular 3/10 to 1/10 of the clear height x.
- the depressions in the cover part advantageously have side walls e.g. with a turning angle of 60 to 90 ° and have a flat top surface.
- This flat top surface can e.g. printed or stuck with labels.
- the present invention also relates to a method for producing the blister packs from sheet-like packaging material by making depressions on the sheet-like packaging material, filling the sheet material forming the base part, covering the base part with cover material and connecting the base part and cover material.
- the packaging material can be present in two webs of packaging material.
- the packaging material of each lane can be the same or different.
- the longitudinal line of symmetry is located between the two tracks and the tracks run symmetrically and in parallel through the following steps a) and c).
- the indentations in the sheet-like packaging material can be made, for example, by means of depths such as stretching, stretching or deep drawing, and in particular by means of stamping out of the pure stretching of the packaging material. Cold forming is particularly preferred.
- the recesses can be made continuously or step by step.
- the depression is expediently made in particular on an endless, e.g. from a roll of material, fed-in sheet-like packaging material. Forming by means of a stamp can be carried out intermittently, a hold-down fixes the sheet-like packaging material and a molding tool forms the depressions out of the stretch in a stamping process.
- the web-shaped packaging material can be weakened, for example by perforating or by notching or cutting through part of the thickness, along the line of symmetry (s).
- the depressions are placed in such a way that a line of symmetry can be placed between at least two rows of depressions, and the depressions and also the shoulder areas between the depressions continue in mirror symmetry over the entire length of the web. If more than one row of depressions is arranged on each side of the line of symmetry, the depressions can be present on the same axis or offset from one another. However, the feature that the depressions must lie in mirror image along a line of symmetry is retained. Depending on the web width and the method, it may be expedient to provide several lines of symmetry. Then comes between two lines of symmetry analogously to lay a dividing line. The dividing line runs parallel to the line of symmetry and, as the name suggests, the sheet-like material is cut lengthways along the dividing line later in the machining process.
- the web-shaped packaging material is weakened along the line of symmetry or along the lines of symmetry, or along the dividing lines separated.
- the indentations in the web-shaped packaging material can be filled with the contents on one side of the line of symmetry.
- the content can be, for example, pills, dragees, tablets, capsules, soft gelatin capsules, ampoules, all of which, for example, contain pharmaceutical active ingredients in their galenical formulations. It is also possible to pack luxury foods in this way. This can be, for example, sweets, spices or the like.
- such recesses can also be made with technical articles, such as batteries in the form of button cells or filigree components for machines or apparatus, or electronic components, e.g. be filled for the spare parts trade.
- the ingredients are filled into the recesses on one side of the line of symmetry and this side of the packaging material provided with recesses thus forms a base part.
- On the other side of the line of symmetry are the other depressions arranged in mirror image. These depressions are empty.
- the web-shaped packaging material may be weakened along the line of symmetry in some cases. Of course, this weakening can only take place at the time after filling. If the line of symmetry is weakened, the web-shaped packaging material can be folded over along this weakening and the folded-over part of the web-shaped packaging material now forms the cover part.
- flat shoulder surfaces remain, both on the base and on the cover part. Since there is a line of symmetry, the depressions come to lie precisely on one another and accordingly the shoulder surfaces come to lie precisely on one another.
- the shoulders and in particular the smooth and flat shoulder surfaces are connected to one another over the full or partial area.
- This connection can be made by the fact that web-shaped packaging material on the shoulder side contains a sealing layer and the sealing layer is activated for example by pressure and / or temperature.
- the sealing tool which transmits the pressure and / or the temperature to the sheet-like packaging material, the shoulders can be sealed against one another over the entire surface or only partially.
- at least the shoulders of the cover part or of the base part or of the base and cover part contain a sealing film or a sealing wax.
- the shoulders are connected to one another by means of a sealing tool and in particular a contour sealing tool using heat and / or pressure.
- Sealing by means of a contour sealing tool enables partial sealing of the shoulders against one another, each recess being surrounded by a sealing seam all around. Seal-free zones can be provided for pull tabs etc. It is also possible to provide the web-shaped packaging material with an adhesive over the whole or in part of the shoulder area, preferably after applying the depression, for example by rolling, brushing, knife coating or spraying, the adhesive being a contact adhesive or the adhesive being able to be applied by pressure and / or heat can be activated. This can be, for example, one- or two-component epoxy or polyurethane adhesives, or it can be vinyl acetate adhesives, etc.
- each depression in the base part is covered by a depression in the cover part and the depressions in the base part and the depressions in the cover part form courtyards and in the courtyards the content is included.
- the blister packs have a plane of symmetry that lies exactly at the point of contact between the base and cover part.
- connection in the shoulder area can be separable or can be peelable.
- separable is meant that the connection is undetachable and the contents of the package can only be removed by destroying the packaging material, such as tearing, cutting, etc.
- the connection can also be peelable or peelable, i.e. the adhesive or sealing layer breaks in itself or delaminates between two layers. This means that the base and lid material remains undamaged when the contents of the packaging are removed.
- preliminary products for the blister packs are also produced from the sheet-like packaging material, ie endless blister packs are produced.
- the sheet-like packaging material or the preliminary product for the blister packs can be made into the actual blister pack by cutting, cutting or punching.
- the web-shaped packaging material can already be cut or punched after the weakening and dividing lines have been attached and before the depressions have been filled. This method is less advantageous and therefore the web-shaped preliminary product, ie the still web-shaped blister pack, is preferably used the filled and covered with the lid part, the bottom part and the lid part are already connected to one another, cut to size in the package, as cut or punched out.
- the blister pack can also be divided into individual portions by applying weakenings in the longitudinal and transverse directions in the shoulder area between the courtyards. Hole punchings can also be made in the intersection of longitudinal and transverse perforations in order to create tear-open tabs. Any edge contour can be formed simultaneously with cutting or punching.
- the finished die-cut blister packs can then be fed to a cartoning system, for example.
- a reduction in base area of up to 40% can be achieved.
- This enables relatively large dosage forms of medication, e.g.
- capsules or ampoules in already introduced or standardized pack sizes or to reduce the known pack sizes in their dimensions.
- a previous blister pack with 10 wells has an external dimension of 144 x 98 mm
- external dimensions of 115 x 77 mm can be achieved.
- the content in this example is a capsule with a diameter of 9.4 mm and a length of 26.6 mm.
- FIG. 1 shows a web-shaped packaging material 10, which already has two double rows of depressions 11, 12 attached, for example by reshaping from the expansion of the packaging material.
- the web-shaped packaging material 10 has a line of symmetry 13.
- the depressions 11 and the depressions 12 are arranged in mirror image on both sides of the symmetry line 13.
- the web-shaped packaging material can be of substantially greater width than shown here and can for example have a large number of rows of depressions 11 which are in rows of one, two, three, etc., on both sides of a line of symmetry 13. With a large web width of the web-shaped packaging material 10, several lines of symmetry 13 can be provided.
- the material can be separated into two or more webs along dividing lines corresponding to the lines of symmetry.
- one side edge of the sheet-like packaging material 10 can represent a dividing line cut edge 22, while the other side edge represents the original edge 23 of the sheet-like packaging material.
- the sheet-like packaging material 10 provided with depressions 11, 12 has a line of symmetry 13. On one side of the line of symmetry are the depressions 11, which later form the lid, and on the other side of the symmetry line 13, the depressions 12 are attached, which belong to the bottom part and are filled with the contents of the package.
- the depressions 11 and 12 are each surrounded by the shoulders 25.
- a weakening of the web-shaped packaging material 10 is applied along the line of symmetry 13.
- the weakening line can be achieved, for example, by cutting through part of the thickness of the sheet-like material 10, or by notches, scratches or perforations.
- the weakening of the material can be done mechanically or, if necessary, also by thermal measures, e.g. B. by laser beams.
- FIG. 1 a shows a top view of the prepared sheet-like packaging material 10 and FIG. 1 b shows a cross section through the sheet-like packaging material 10.
- the depressions 12 can be filled with the contents.
- the content can be, for example, soft gelatin capsules, capsules, dragées, tablets or ampoules.
- FIG. 2 shows a further step in the production of the blister packs according to the invention.
- FIG. 2a again shows the top view
- FIG. 2b shows a cross section through an emerging blister pack of sheet-like packaging material 10.
- the sheet-like packaging material 10 was folded over along the line of symmetry 13 such that the shoulders of the two sheet halves touch.
- the depressions 11 are now associated with the covers, while the depressions 12 belong to the base part.
- a fold 16 is formed by folding over along the line of symmetry 13.
- On the shoulders 25, a connection between the base part and the cover part was achieved by sealing 24.
- the depressions 11 and 12 of the lid and bottom part form courtyards in which the content 15 is received.
- a plane of symmetry 14 can be placed through the blister pack that forms.
- the web-shaped packaging material 10 is arranged symmetrically or in mirror image on both sides of the plane 14. In the area of the plane of symmetry 14 there is also the seal 24 between the shoulders 25.
- the depressions of the base part and cover part can also have a different height, in which case only the edges of the depressions and the shoulders lie symmetrically one above the other.
- FIG. 3 shows a further stage in the production of the blister packs.
- the blister packs 18 are made from the web-shaped packaging material 10 and have the fold 16 on one side edge and the edge 23 on the other side edge.
- the depressions 11 of the cover are surrounded by the shoulders 25.
- the endless band has been cut into individual blister packs 18, with the formation of cut edges 17.
- the cutting can also be done, for example, by a thermal process, such as with a laser beam.
- the blister packs 18 can be packaged in the present form, for example, in a cardboard sleeve, which also contains, for example, an instruction leaflet, or can be layered and packaged into large containers, etc. It is also possible to further package the blister pack 18 present.
- Such a further assembled blister pack 18 is shown in plan view in FIG.
- the recesses of the lid 11 can be seen, under which the contents, for example an ampoule, capsule, soft gelatin capsule, pill or dragee, are located.
- the recess 11 is surrounded by the shoulders 25.
- the further processing includes cutting an outer contour 20.
- the fold 16 shown in the embodiment according to FIG. 3 was removed and, for example, marking aids 21 were formed.
- the outer contour 20 is generally formed by stamping.
- perforations 19 were made in the shoulder area between the individual courtyards, which are formed by the depressions in the lid 11 and the corresponding depressions in the bottom. With these perforations 19, one or more of the courtyards filled with content can be separated and, for example, daily portions etc. can be stored and used up separately from the rest of the packaging.
- the tear-open aids 21 could also be attached inside the outer contour in the area of the perforations 19 by punching etc.
- the courtyard can, for example, be opened by tearing along the tearing aid 21 and the contents can be removed. At most, it is also possible that the contents are made by pressing in the base part. The contents of the pack then push against the lid part and, due to the tension generated and the inelasticity of the material, the lid part bursts and the contents are released. Tear tabs can be produced, for example, by contour sealing of the base and cover part and / or by punching. The contents of the packaging can be uncovered by grasping the pull tabs and peeling off the base and lid material.
- the blister pack 18 according to FIG. 4 can in turn be packaged, for example, in a cardboard sleeve or layered and packaged into a large packaging.
- the shoulder areas are expediently chosen to be so wide that when blister packs are layered on top of one another, the depressions of an overlying blister between two Find recesses in the blister below.
- the stack height of two or more blisters can thus be reduced.
- FIG. 5 shows a cross section through a blister pack according to the present invention in a preferred embodiment.
- the blister pack 18 has the depressions in the lid part 11 and the depressions in the bottom part 12, which are arranged on a plane of symmetry 14.
- the depressions 11 and 12 form courtyards for the contents of the pack, e.g. for the capsules 15.
- the clear height x of the courtyards is divided into, for example, 1/3 for the depression in the lid part and 2/3 for the depression in the bottom part 12.
- the depressions in the bottom part 12 have a shell shape, respectively. Form a half-shell with a turning angle of about 45 °, while the depressions in the cover part have steep walls and a flat top surface.
- the depression of the base part 12 in the form of a half-shell can easily be filled with the content and the shaping of the half-shell represents, for example, 5: 1 to 0.5: 1 and preferably 3: 1 to 1: 1 by the depth ratio (shell width to depth) , no high demands on the packaging material.
- the bowl shape holds the contents securely in place during the further processing process.
- the depression in the cover part 11 has e.g. an even lower depression ratio of, for example, 10: 1 to 0.5: 1, advantageously 5: 1 to 2: 1 and preferably 3: 1 to 2: 1, and walls of great steepness, i.e. up to 90 °.
- This enables the design of smooth, flat cover surfaces 26, which can be printed, glued or otherwise configured.
- the present invention also relates to the use of the blister packs for the absorption of ingredients such as pills, dragees, tablets, capsules, soft gelatin capsules, ampoules, foods such as sweets, spices or technical articles.
- the use of the blister packs for soft gelatin capsules is particularly preferred.
- the shape of the depressions can be selected. Examples of shapes of the depressions are half or partial shells or half or partial spherical shapes or half or partial cylindrical shapes from a partially cylindrical body and terminal hemispherical or partially spherical ends.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Chemical & Material Sciences (AREA)
- Composite Materials (AREA)
- Packages (AREA)
- Containers And Plastic Fillers For Packaging (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH2580/94 | 1994-08-23 | ||
| CH02580/94A CH689305A5 (de) | 1994-08-23 | 1994-08-23 | Blisterpackung. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP0703157A1 true EP0703157A1 (fr) | 1996-03-27 |
| EP0703157B1 EP0703157B1 (fr) | 1998-11-04 |
Family
ID=4236992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP95810514A Expired - Lifetime EP0703157B1 (fr) | 1994-08-23 | 1995-08-16 | Emballage du type blister |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US5911325A (fr) |
| EP (1) | EP0703157B1 (fr) |
| JP (1) | JPH0858840A (fr) |
| AU (1) | AU693573B2 (fr) |
| CH (1) | CH689305A5 (fr) |
| DE (1) | DE59504127D1 (fr) |
| DK (1) | DK0703157T3 (fr) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007012628A3 (fr) * | 2005-07-27 | 2007-06-07 | Boehringer Ingelheim Int | Plaquettes alveolaires pour medicaments |
| WO2011062568A1 (fr) * | 2009-11-23 | 2011-05-26 | Bilgic Mahmut | Plaquette thermoformée portant une composition de poudre sèche |
| WO2011037549A3 (fr) * | 2009-09-23 | 2011-06-09 | Bilgic Mahmut | Formulation de poudre sèche de tiotropium contenue dans une bande alvéolée thermoformée |
| WO2011037551A3 (fr) * | 2009-09-23 | 2011-06-09 | Mahmut Bilgic | Bande alvéolée thermoformée contenant une combinaison qui renferme du tiotropium |
| CH702668A1 (de) * | 2010-02-04 | 2011-08-15 | Christian Schuetz | Setverpackung zum sterilen verpacken einer mehrzahl von fläschchen oder einer mehrzahl von fläschchenverschlüssen. |
| EP1284711B2 (fr) † | 2000-05-25 | 2012-03-28 | Cilag AG | PROCEDE POUR LA FABRICATION d'UN EMBALLAGE COQUE CONTENANT DES COMPRIMES DE TOPIRAMATE |
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| CH689305A5 (de) * | 1994-08-23 | 1999-02-15 | Alusuisse Lonza Services Ag | Blisterpackung. |
| DE59606545D1 (de) * | 1995-12-12 | 2001-04-12 | Alusuisse Tech & Man Ag | Verfahren zum Herstellen von Blisterverpackungen |
| EP1005413B1 (fr) * | 1997-08-18 | 2002-05-08 | R.P. Scherer Corporation | Formation de reperes dans la base d'un emballage coque permettant de transferer ces derniers sur un corps coule dans l'emballage coque |
| US6269671B1 (en) * | 1998-09-16 | 2001-08-07 | Alusuisse Technology & Management Ltd. | Process for manufacturing shaped packaging |
| JP2000281130A (ja) * | 1999-03-30 | 2000-10-10 | Dai Ichi Seiyaku Co Ltd | ブリスター包装体、底材および樹脂シート |
| IT1311383B1 (it) * | 1999-12-30 | 2002-03-12 | Ima Spa | Metodo e apparecchiatura per la formatura di un nastro alveolato diconfezioni blister in macchine blisteratrici. |
| US6464566B1 (en) * | 2000-06-29 | 2002-10-15 | Lsi Logic Corporation | Apparatus and method for linearly planarizing a surface of a semiconductor wafer |
| GB0020964D0 (en) * | 2000-08-25 | 2000-10-11 | Reckitt & Colmann Prod Ltd | Improvements in or relating to containers |
| GB2375542A (en) * | 2001-05-17 | 2002-11-20 | Reckitt Benckiser | Water soluble container |
| GB0225621D0 (en) | 2002-11-02 | 2002-12-11 | Glaxo Group Ltd | Medicament carrier |
| US20040093835A1 (en) * | 2002-11-18 | 2004-05-20 | Todd Siegel | Systems and methods for forming blister packages with support members for pharmaceutical product packaging |
| JP4439206B2 (ja) * | 2002-12-10 | 2010-03-24 | シーケーディ株式会社 | 包装体及び異物検査方法 |
| FR2866865A1 (fr) * | 2004-02-27 | 2005-09-02 | Valois Sas | Bande de blisters pour inhalateur |
| US7266897B2 (en) * | 2004-06-21 | 2007-09-11 | Laserline Mfg., Inc. | Self-aligning, self plumbing baseline instrument |
| US20050284789A1 (en) * | 2004-06-29 | 2005-12-29 | Carespodi Dennis L | Laser-scored push-through blister backing and methods of making same |
| DE102004062864A1 (de) * | 2004-12-21 | 2006-06-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Folienbehälter |
| GB2425115A (en) * | 2005-04-15 | 2006-10-18 | Vectura Group Plc | Blister pack |
| GB2433887A (en) * | 2006-01-04 | 2007-07-11 | Reckitt Benckiser Healthcare | Pack for phenothiazine derivatives |
| US20070295060A1 (en) * | 2006-06-13 | 2007-12-27 | Delgado Juan C | Ampoule card leak detector assembly |
| US9216850B2 (en) | 2006-09-26 | 2015-12-22 | Intercontinental Great Brands Llc | Rupturable substrate |
| PL2069215T3 (pl) * | 2006-09-26 | 2012-10-31 | Intercontinental Great Brands Llc | Opakowanie blistrowe podatne na przerwanie |
| AT504573B1 (de) * | 2006-12-04 | 2010-09-15 | Ebewe Pharma Gmbh Nfg Kg | Verpackung für kleinvolumige flaschen |
| USD548618S1 (en) | 2006-12-06 | 2007-08-14 | Eveready Battery Company, Inc. | Zinc-air hearing aid battery package |
| USD549111S1 (en) | 2006-12-06 | 2007-08-21 | Eveready Battery Company, Inc. | Zinc-air hearing aid battery package |
| USD548619S1 (en) | 2006-12-06 | 2007-08-14 | Eveready Battery Company, Inc. | Zinc-air hearing aid battery package |
| USD548620S1 (en) | 2006-12-06 | 2007-08-14 | Eveready Battery Company, Inc. | Zinc-air hearing aid battery package |
| USD556601S1 (en) | 2006-12-06 | 2007-12-04 | Eveready Battery Company, Inc. | Zinc-air hearing aid battery package |
| USD548617S1 (en) | 2006-12-06 | 2007-08-14 | Eveready Battery Company, Inc. | Zinc-air hearing aid battery package |
| GB2450117A (en) * | 2007-06-13 | 2008-12-17 | Reckitt Benckiser Healthcare | A water- and oxygen-occlusive blister tablet pack |
| CA2699634C (fr) * | 2007-09-14 | 2015-06-09 | Mystic Pharmaceuticals, Inc. | Procede de faconnage d'un receptacle par emboutissage profond |
| US8079475B2 (en) | 2008-01-24 | 2011-12-20 | Sonoco Development, Inc. | Blister package |
| CA2716988A1 (fr) * | 2008-02-28 | 2009-09-03 | Winpak Heat Seal Packaging Inc. | Feuille opercule revetue par extrusion pour emballage-coque enfoncable |
| US8684632B2 (en) | 2010-12-08 | 2014-04-01 | Laserline Mfg., Inc. | Systems and methods for laying out and installing a solar panel array |
| US20130142916A1 (en) * | 2011-03-25 | 2013-06-06 | Michael J. Ure | Spice packaging and distribution including the use of scannable codes |
| US10450126B2 (en) | 2011-07-06 | 2019-10-22 | Sonoco Development, Inc. | Die-cut patterns for blister package |
| US9138378B2 (en) | 2011-07-06 | 2015-09-22 | Sonoco Development, Inc. | Blister package and method of forming same |
| USD694644S1 (en) | 2012-03-28 | 2013-12-03 | Aventisub Ii Inc. | Clamshell package having blisters |
| US8919559B2 (en) | 2012-03-28 | 2014-12-30 | Aventisub Ii Inc. | Package with break-away clamshell |
| USD697813S1 (en) | 2012-03-28 | 2014-01-21 | Aventisub Ii Inc. | Clamshell having blisters received therein |
| USD687313S1 (en) | 2012-03-28 | 2013-08-06 | Aventisub Ii Inc. | A-shaped blister card |
| USD695625S1 (en) | 2012-03-28 | 2013-12-17 | Aventisub Ii Inc. | Package for product |
| US8899419B2 (en) | 2012-03-28 | 2014-12-02 | Aventisub Ii Inc. | Package with break-away clamshell |
| USD693695S1 (en) | 2012-03-28 | 2013-11-19 | Aventisub Ii Inc. | Package for product |
| GB2531987A (en) * | 2014-05-07 | 2016-05-11 | Kraft Foods R&D Inc | An item of packaging |
| DE102014106427A1 (de) * | 2014-05-08 | 2015-11-12 | Technische Universität Dresden | Verfahren und Vorrichtung zur Herstellung von Formteilen aus einer Faserwerkstoffbahn |
| WO2016118605A1 (fr) | 2015-01-21 | 2016-07-28 | Mylan Inc. | Système d'emballage de médicament et de régime posologique |
| EP3135602A1 (fr) * | 2015-08-25 | 2017-03-01 | Bayer Pharma Aktiengesellschaft | Blister |
| JP6990031B2 (ja) * | 2017-03-17 | 2022-01-12 | 藤森工業株式会社 | 積層体、ブリスター容器、及びプレススルーパッケージ |
| US11554104B2 (en) | 2017-08-18 | 2023-01-17 | The Schepens Eye Research Institute, Inc. | Compositions for the treatment of dry eye and methods of use thereof |
| CA3110427A1 (fr) | 2017-10-24 | 2019-05-02 | Danapak Flexibles A/S | Stratifie en feuille, emballage-coque et procede de fabrication |
| US20220331802A1 (en) * | 2021-04-16 | 2022-10-20 | The Regents Of The University Of California | Burstable liquid storage package for biological materials and valve substitution |
| WO2023194545A1 (fr) * | 2022-04-08 | 2023-10-12 | Knapp Ag | Emballage de médicament |
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| GB644584A (en) * | 1945-10-31 | 1950-10-11 | Charles Nicolle | Improvements in or relating to packages for small objects such as tablets and the like |
| US2578444A (en) * | 1943-10-12 | 1951-12-11 | Nicolle Charles | Multicapsule sheet |
| CH326033A (de) * | 1954-04-17 | 1957-11-30 | Faber Castell A W | Verpackung mit Kugelschreiberminen |
| GB897083A (en) * | 1958-06-25 | 1962-05-23 | Rowntree And Company Ltd | Improvements in the manufacture of wrapped pieces of mouldable solid materials |
| US4125190A (en) * | 1977-08-03 | 1978-11-14 | Sharp Corporation | Child-resistant blister package |
| DE2919713A1 (de) * | 1979-05-16 | 1980-11-20 | Helmut Zanker | Kindergesicherte arzneimittelverpackung |
| EP0118975A1 (fr) * | 1983-02-09 | 1984-09-19 | The Wiggins Teape Group Limited | Feuille pour emballage blister |
| DE3311634A1 (de) * | 1982-08-23 | 1984-10-04 | Siemens AG, 1000 Berlin und 8000 München | Verfahren zum verbinden zweier naepfchengurtenden |
| US4782951A (en) * | 1986-03-20 | 1988-11-08 | Oscar Mayer Foods Corporation | Reclosable package and method of making reclosable package |
| EP0587957A1 (fr) * | 1992-09-14 | 1994-03-23 | Ciba-Geigy Ag | Emballage pour suppositoires |
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| CH689305A5 (de) * | 1994-08-23 | 1999-02-15 | Alusuisse Lonza Services Ag | Blisterpackung. |
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1994
- 1994-08-23 CH CH02580/94A patent/CH689305A5/de not_active IP Right Cessation
-
1995
- 1995-08-09 AU AU28437/95A patent/AU693573B2/en not_active Ceased
- 1995-08-16 DE DE59504127T patent/DE59504127D1/de not_active Expired - Lifetime
- 1995-08-16 EP EP95810514A patent/EP0703157B1/fr not_active Expired - Lifetime
- 1995-08-16 DK DK95810514T patent/DK0703157T3/da active
- 1995-08-23 JP JP7214714A patent/JPH0858840A/ja active Pending
-
1997
- 1997-08-22 US US08/916,593 patent/US5911325A/en not_active Expired - Lifetime
-
1999
- 1999-01-28 US US09/239,874 patent/US6055794A/en not_active Expired - Fee Related
-
2000
- 2000-02-24 US US09/512,499 patent/US6212858B1/en not_active Expired - Lifetime
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2578444A (en) * | 1943-10-12 | 1951-12-11 | Nicolle Charles | Multicapsule sheet |
| GB644584A (en) * | 1945-10-31 | 1950-10-11 | Charles Nicolle | Improvements in or relating to packages for small objects such as tablets and the like |
| CH326033A (de) * | 1954-04-17 | 1957-11-30 | Faber Castell A W | Verpackung mit Kugelschreiberminen |
| GB897083A (en) * | 1958-06-25 | 1962-05-23 | Rowntree And Company Ltd | Improvements in the manufacture of wrapped pieces of mouldable solid materials |
| US4125190A (en) * | 1977-08-03 | 1978-11-14 | Sharp Corporation | Child-resistant blister package |
| DE2919713A1 (de) * | 1979-05-16 | 1980-11-20 | Helmut Zanker | Kindergesicherte arzneimittelverpackung |
| DE3311634A1 (de) * | 1982-08-23 | 1984-10-04 | Siemens AG, 1000 Berlin und 8000 München | Verfahren zum verbinden zweier naepfchengurtenden |
| EP0118975A1 (fr) * | 1983-02-09 | 1984-09-19 | The Wiggins Teape Group Limited | Feuille pour emballage blister |
| US4782951A (en) * | 1986-03-20 | 1988-11-08 | Oscar Mayer Foods Corporation | Reclosable package and method of making reclosable package |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1284711B2 (fr) † | 2000-05-25 | 2012-03-28 | Cilag AG | PROCEDE POUR LA FABRICATION d'UN EMBALLAGE COQUE CONTENANT DES COMPRIMES DE TOPIRAMATE |
| WO2007012628A3 (fr) * | 2005-07-27 | 2007-06-07 | Boehringer Ingelheim Int | Plaquettes alveolaires pour medicaments |
| US9168342B2 (en) | 2005-07-27 | 2015-10-27 | Boehringer Ingelheim International Gmbh | Medicament blister |
| WO2011037549A3 (fr) * | 2009-09-23 | 2011-06-09 | Bilgic Mahmut | Formulation de poudre sèche de tiotropium contenue dans une bande alvéolée thermoformée |
| WO2011037551A3 (fr) * | 2009-09-23 | 2011-06-09 | Mahmut Bilgic | Bande alvéolée thermoformée contenant une combinaison qui renferme du tiotropium |
| WO2011062568A1 (fr) * | 2009-11-23 | 2011-05-26 | Bilgic Mahmut | Plaquette thermoformée portant une composition de poudre sèche |
| EP2503977B1 (fr) | 2009-11-23 | 2015-06-10 | Sima Patent ve Lisanslama Hizmetleri Ltd.Sti. | Plaquette thermoformée portant une composition de poudre sèche |
| CH702668A1 (de) * | 2010-02-04 | 2011-08-15 | Christian Schuetz | Setverpackung zum sterilen verpacken einer mehrzahl von fläschchen oder einer mehrzahl von fläschchenverschlüssen. |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2843795A (en) | 1996-03-07 |
| DE59504127D1 (de) | 1998-12-10 |
| AU693573B2 (en) | 1998-07-02 |
| US5911325A (en) | 1999-06-15 |
| CH689305A5 (de) | 1999-02-15 |
| US6055794A (en) | 2000-05-02 |
| JPH0858840A (ja) | 1996-03-05 |
| US6212858B1 (en) | 2001-04-10 |
| EP0703157B1 (fr) | 1998-11-04 |
| DK0703157T3 (da) | 1999-07-19 |
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Free format text: ORIGINAL CODE: 0009012 |
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| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): CH DE DK GB IT LI SE |
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