EP0711111A4 - Neuer stammzellen-marker - Google Patents

Neuer stammzellen-marker

Info

Publication number
EP0711111A4
EP0711111A4 EP94924518A EP94924518A EP0711111A4 EP 0711111 A4 EP0711111 A4 EP 0711111A4 EP 94924518 A EP94924518 A EP 94924518A EP 94924518 A EP94924518 A EP 94924518A EP 0711111 A4 EP0711111 A4 EP 0711111A4
Authority
EP
European Patent Office
Prior art keywords
stem cell
cell marker
novel stem
novel
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94924518A
Other languages
English (en)
French (fr)
Other versions
EP0711111A1 (de
Inventor
Bruno Peault
Nobuko Uchida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Systemix Inc
Original Assignee
Systemix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Systemix Inc filed Critical Systemix Inc
Publication of EP0711111A1 publication Critical patent/EP0711111A1/de
Publication of EP0711111A4 publication Critical patent/EP0711111A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2306—Interleukin-6 (IL-6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1394—Bone marrow stromal cells; whole marrow

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP94924518A 1993-07-29 1994-07-29 Neuer stammzellen-marker Withdrawn EP0711111A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10063393A 1993-07-29 1993-07-29
US100633 1993-07-29
PCT/US1994/008574 WO1995003693A1 (en) 1993-07-29 1994-07-29 Novel stem cell marker

Publications (2)

Publication Number Publication Date
EP0711111A1 EP0711111A1 (de) 1996-05-15
EP0711111A4 true EP0711111A4 (de) 1997-09-24

Family

ID=22280745

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94924518A Withdrawn EP0711111A4 (de) 1993-07-29 1994-07-29 Neuer stammzellen-marker

Country Status (5)

Country Link
EP (1) EP0711111A4 (de)
JP (1) JPH09502167A (de)
AU (1) AU7476694A (de)
CA (1) CA2168348A1 (de)
WO (1) WO1995003693A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08157499A (ja) * 1994-12-06 1996-06-18 Systemix Inc 新規な幹細胞マーカータンパク質をコードするヌクレオチド配列、該タンパク質のアミノ酸配列、該タンパク質の発現方法、単離したタンパク質の組成物、および該タンパク質に特異的な抗体
WO1996040875A1 (en) * 1995-06-07 1996-12-19 Novartis Ag Methods for obtaining compositions enriched for hematopoietic stem cells and antibodies for use therein
AU6223196A (en) * 1995-06-07 1996-12-30 Novartis Ag Methods for obtaining compositions enriched for hematopoietic stem cells and antibodies for use therein
US5728581A (en) * 1995-06-07 1998-03-17 Systemix, Inc. Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
US6060052A (en) * 1995-10-30 2000-05-09 Systemix, Inc. Methods for use of Mpl ligands with primitive human hematopoietic stem cells
AU3440797A (en) * 1996-07-01 1998-01-21 Novartis Ag Process of obtaining compositions enriched for hematopoietic stem cells and antibodies for use therein
WO1998021334A2 (en) * 1996-11-13 1998-05-22 Morphogenesis, Inc. Antibody mg1 recognizing a small subset of human hematopoietic cells
WO2004046312A2 (en) 2002-11-15 2004-06-03 The Board Of Trustees Of The University Of Illinois Methods for in vitro expansion of hematopoietic stem cells
US8609411B2 (en) 2007-05-04 2013-12-17 Whitehead Institute For Biomedical Research Ex vivo expansion of human hematopoietic stem cells
WO2011159684A2 (en) 2010-06-15 2011-12-22 Cellular Dynamics International, Inc. Generation of induced pluripotent stem cells from small volumes of peripheral blood

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025216A1 (en) * 1992-06-08 1993-12-23 Becton, Dickinson And Company Human primitive stem cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4714680B1 (en) * 1984-02-06 1995-06-27 Univ Johns Hopkins Human stem cells
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025216A1 (en) * 1992-06-08 1993-12-23 Becton, Dickinson And Company Human primitive stem cells

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
PEAULT B.M. ET AL.: "Surface marker for hemopoietic and endothelial cell lineages in quail that is defined by a monoclonal antibody", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 80, no. 10, May 1983 (1983-05-01), WASHINGTON US, pages 2976 - 2980, XP002035217 *
See also references of WO9503693A1 *
TSUKAMOTO A. ET AL.: "Characterization and Enrichment of Candidate Human Hematopoietic Stem Cells", JOURNAL OF HEMATOTHERAPY, vol. 2, no. 1, 1993, pages 117 - 119, XP002035218 *

Also Published As

Publication number Publication date
AU7476694A (en) 1995-02-28
EP0711111A1 (de) 1996-05-15
WO1995003693A1 (en) 1995-02-09
CA2168348A1 (en) 1995-02-09
JPH09502167A (ja) 1997-03-04

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19960212

AK Designated contracting states

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: UCHIDA, NOBUKO

Inventor name: PEAULT, BRUNO

A4 Supplementary search report drawn up and despatched

Effective date: 19970807

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STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 19990202