EP0759070A4 - Mesenchymzellen aus blut - Google Patents

Mesenchymzellen aus blut

Info

Publication number
EP0759070A4
EP0759070A4 EP94913910A EP94913910A EP0759070A4 EP 0759070 A4 EP0759070 A4 EP 0759070A4 EP 94913910 A EP94913910 A EP 94913910A EP 94913910 A EP94913910 A EP 94913910A EP 0759070 A4 EP0759070 A4 EP 0759070A4
Authority
EP
European Patent Office
Prior art keywords
mesenchymatory
hematogenic
diffusion
cells
mesenchymatory cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94913910A
Other languages
English (en)
French (fr)
Other versions
EP0759070A1 (de
Inventor
Anthony Cerami
Richard J Bucala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Picower Institute for Medical Research
Original Assignee
Picower Institute for Medical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Picower Institute for Medical Research filed Critical Picower Institute for Medical Research
Publication of EP0759070A1 publication Critical patent/EP0759070A1/de
Publication of EP0759070A4 publication Critical patent/EP0759070A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Dermatology (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP94913910A 1994-03-16 1994-03-16 Mesenchymzellen aus blut Withdrawn EP0759070A4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/002850 WO1995025164A1 (en) 1994-03-16 1994-03-16 Blood-borne mesenchymal cells

Publications (2)

Publication Number Publication Date
EP0759070A1 EP0759070A1 (de) 1997-02-26
EP0759070A4 true EP0759070A4 (de) 1998-03-11

Family

ID=22242354

Family Applications (1)

Application Number Title Priority Date Filing Date
EP94913910A Withdrawn EP0759070A4 (de) 1994-03-16 1994-03-16 Mesenchymzellen aus blut

Country Status (5)

Country Link
EP (1) EP0759070A4 (de)
JP (1) JPH09510348A (de)
KR (1) KR100352057B1 (de)
AU (1) AU693441B2 (de)
WO (1) WO1995025164A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1099754A1 (de) * 1999-11-10 2001-05-16 Universiteit Leiden Mesenchym-Stammzellen und/oder Vorlaüferzellen, ihre Isolierung und ihre Verwendung
WO2011022045A2 (en) * 2009-08-17 2011-02-24 Singh Ashok K Apparatus and process for generating and harvesting adult stem cells and fluid associated with it from skin and omentum for medical, cosmetic, and veterinary use
CN115287260A (zh) * 2022-06-30 2022-11-04 江苏汇先医药技术有限公司 一种t细胞的富集方法

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ALLGOWER, M. AND HULLIGER, L.: "Origin of fibroblasts from mononuclear blood cells: a study on in vitro formation of the collagen precursor, hydroxyproline, in buffy coat cultures", SURGERY, vol. 47, 1960, pages 603, XP002051349 *
BROWN, J. ET AL.: "The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic preogenitor cell lines, brain and embryonic fibroblasts", INTERNATIONAL IMMUNOLOGY, vol. 3, no. 2, February 1991 (1991-02-01), pages 175 - 184, XP002051351 *
BUCALA, R. ET AL.: "Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair", MOLECULAR MEDICINE, vol. 1, no. 1, November 1994 (1994-11-01), pages 71-81, XP002051352 *
See also references of WO9525164A1 *
SIMMONS, P.J. AND TOROK-STORB, B.: "CD34-expression by stromal precursors in normal human adult bone marrow", BLOOD, vol. 78, no. 11, 1991, pages 2848 - 2853, XP002051348 *
VILJANTO, J. AND RAJAMÄKI, A.: "Cellular patterns in the early phase of healing wounds in children", SCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY, vol. 10, no. 2, 1976, pages 83 - 89, XP002051350 *

Also Published As

Publication number Publication date
AU6588494A (en) 1995-10-03
WO1995025164A1 (en) 1995-09-21
EP0759070A1 (de) 1997-02-26
KR970701777A (ko) 1997-04-12
JPH09510348A (ja) 1997-10-21
KR100352057B1 (ko) 2003-01-24
AU693441B2 (en) 1998-07-02

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