EP0784627A4 - Procede de preparation d'acides androsta-3,5-diene-3-carboxyliques a substitution en 17 beta - Google Patents

Procede de preparation d'acides androsta-3,5-diene-3-carboxyliques a substitution en 17 beta

Info

Publication number
EP0784627A4
EP0784627A4 EP95936242A EP95936242A EP0784627A4 EP 0784627 A4 EP0784627 A4 EP 0784627A4 EP 95936242 A EP95936242 A EP 95936242A EP 95936242 A EP95936242 A EP 95936242A EP 0784627 A4 EP0784627 A4 EP 0784627A4
Authority
EP
European Patent Office
Prior art keywords
dien
beta
producing
carbonic acid
substituted androsta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95936242A
Other languages
German (de)
English (en)
Other versions
EP0784627A1 (fr
Inventor
Neil Howard Baine
Michael Anthony Mcguire
Marvin Sungwhan Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9420063A external-priority patent/GB9420063D0/en
Priority claimed from GBGB9515925.7A external-priority patent/GB9515925D0/en
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0784627A1 publication Critical patent/EP0784627A1/fr
Publication of EP0784627A4 publication Critical patent/EP0784627A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
EP95936242A 1994-10-05 1995-10-04 Procede de preparation d'acides androsta-3,5-diene-3-carboxyliques a substitution en 17 beta Withdrawn EP0784627A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9420063A GB9420063D0 (en) 1994-10-05 1994-10-05 Process
GB9420063 1994-10-05
GBGB9515925.7A GB9515925D0 (en) 1995-08-03 1995-08-03 Process
GB9515925 1995-08-03
PCT/US1995/012710 WO1996011206A1 (fr) 1994-10-05 1995-10-04 Procede de preparation d'acides androsta-3,5-diene-3-carboxyliques a substitution en 17 beta

Publications (2)

Publication Number Publication Date
EP0784627A1 EP0784627A1 (fr) 1997-07-23
EP0784627A4 true EP0784627A4 (fr) 1998-05-06

Family

ID=26305742

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95936242A Withdrawn EP0784627A4 (fr) 1994-10-05 1995-10-04 Procede de preparation d'acides androsta-3,5-diene-3-carboxyliques a substitution en 17 beta

Country Status (4)

Country Link
EP (1) EP0784627A4 (fr)
JP (1) JPH10507176A (fr)
AU (1) AU3826095A (fr)
WO (1) WO1996011206A1 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994011386A1 (fr) * 1992-11-18 1994-05-26 Smithkline Beecham Corporation Acyl-3-carboxy-3,5-dienes a substitution 17-alkyle et 17-beta et utilisation de ces derniers pour inhiber la 5-alpha-reductase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4910226A (en) * 1987-04-29 1990-03-20 Smithkline Beckman Corporation Steroid 5-alpha-reductase inhibitors
US5032586A (en) * 1989-08-24 1991-07-16 Smithkline Beecham Corporation 7-keto or hydroxy 3,5-diene steroids as inhibitors of steroid 5-alpha reductase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994011386A1 (fr) * 1992-11-18 1994-05-26 Smithkline Beecham Corporation Acyl-3-carboxy-3,5-dienes a substitution 17-alkyle et 17-beta et utilisation de ces derniers pour inhiber la 5-alpha-reductase

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9611206A1 *

Also Published As

Publication number Publication date
WO1996011206A1 (fr) 1996-04-18
EP0784627A1 (fr) 1997-07-23
AU3826095A (en) 1996-05-02
JPH10507176A (ja) 1998-07-14

Similar Documents

Publication Publication Date Title
DE69516188D1 (de) Verfahren zur herstellung von therephthalsäure
DE59708146D1 (de) Verfahren zur herstellung von polyalkoholen
DE69618020D1 (de) Verfahren zur herstellung von hydrofluorethern
DE69726581D1 (de) Verfahren zur herstellung von cyclohexandimethanol
DE69512250D1 (de) Verfahren zur herstellung von 1,1,1,3,3,3- hexafluorpropan
DE69913666D1 (de) Verfahren zur herstellung von di-methyl-naphthalinen
DE69911398D1 (de) Verfahren zur herstellung von 4-aminodiphenylaminen
DE69519379D1 (de) Verfahren zur herstellung von trifluorethylene
DE69711669D1 (de) VERFAHREN ZUR HERSTELLUNG VON d,1-ALPHA-TOCOPHEROL
DE69513172D1 (de) Verfahren zur herstellung von methacrolein
ATE194850T1 (de) Verfahren zur herstellung von peroxiperfluoropolyxyalkylene
DE59705109D1 (de) Verfahren zur herstellung von arylcyanaten
DE69715616D1 (de) Verfahren zur herstellung von 5-amino-2,4,6-triiod-benzoldicarbonsäurederivate
DE69510466D1 (de) Verfahren zur herstellung von n-phosphonomethylglyzin
DE69510087D1 (de) Verfahren zur herstellung von 5-chlor-2,3-dihydro-1h-inden-1-on
DE69716452D1 (de) Verfahren zur herstellung von beta-amino-alpha-hydroxycarbonsaeure-derivaten
DE69910995D1 (de) Verfahren zur herstellung von fluorkohlenwasserstoffen
DE59901552D1 (de) Verfahren zur herstellung von polyalkylenarylaten
DE59704683D1 (de) Verfahren zur herstellung von 6-aminocapronitril
DE69516400D1 (de) Verfahren zur herstellung von nikotinsäure
DE69608442D1 (de) Verfahren zur herstellung von 5-formylvelerionsäure
ATE198318T1 (de) Verfahren zur herstellung von n-acetonylbenzamide
DE59509620D1 (de) Verfahren zur herstellung von acyloinen
DE69514369D1 (de) Verfahren zur herstellung von pentafluorethan
DE59704682D1 (de) Verfahren zur herstellung von 6-aminocapronitril

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): BE CH DE FR GB IT LI NL

17P Request for examination filed

Effective date: 19970422

A4 Supplementary search report drawn up and despatched

Effective date: 19980320

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): BE CH DE FR GB IT LI NL

18D Application deemed to be withdrawn

Effective date: 19990605