EP0814661A4 - Enzymes 7, 8 et 9 de conjugaison d'ubiquitine - Google Patents

Enzymes 7, 8 et 9 de conjugaison d'ubiquitine

Info

Publication number
EP0814661A4
EP0814661A4 EP95910898A EP95910898A EP0814661A4 EP 0814661 A4 EP0814661 A4 EP 0814661A4 EP 95910898 A EP95910898 A EP 95910898A EP 95910898 A EP95910898 A EP 95910898A EP 0814661 A4 EP0814661 A4 EP 0814661A4
Authority
EP
European Patent Office
Prior art keywords
ubiquitine
conjugation
enzymes
ubiquitine conjugation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95910898A
Other languages
German (de)
English (en)
Other versions
EP0814661A1 (fr
Inventor
Jian Ni
Reiner Gentz
Mark D Adams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP0814661A1 publication Critical patent/EP0814661A1/fr
Publication of EP0814661A4 publication Critical patent/EP0814661A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP95910898A 1995-01-31 1995-01-31 Enzymes 7, 8 et 9 de conjugaison d'ubiquitine Withdrawn EP0814661A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1995/001250 WO1996023410A1 (fr) 1995-01-31 1995-01-31 Enzymes 7, 8 et 9 de conjugaison d'ubiquitine

Publications (2)

Publication Number Publication Date
EP0814661A1 EP0814661A1 (fr) 1998-01-07
EP0814661A4 true EP0814661A4 (fr) 2004-08-11

Family

ID=22248591

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95910898A Withdrawn EP0814661A4 (fr) 1995-01-31 1995-01-31 Enzymes 7, 8 et 9 de conjugaison d'ubiquitine

Country Status (4)

Country Link
EP (1) EP0814661A4 (fr)
JP (1) JPH11501802A (fr)
AU (1) AU1869095A (fr)
WO (1) WO1996023410A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5847094A (en) * 1996-11-13 1998-12-08 Incyte Pharmaceuticals, Inc. UBCH7-like ubiquitin-conjugating enzyme
US5976837A (en) * 1997-03-14 1999-11-02 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US5863779A (en) * 1997-08-21 1999-01-26 Incyte Pharmaceuticals, Inc. UBC7-like ubiquitin-conjugating enzyme
US5968747A (en) * 1997-12-12 1999-10-19 Incyte Pharmaceuticals, Inc. Ubiquitin-like conjugating protein
WO1999050421A1 (fr) * 1998-03-27 1999-10-07 University Of Leeds Enzyme conjuguant l'ubiquitine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995018974A2 (fr) * 1994-01-04 1995-07-13 Mitotix, Inc. Enzymes conjuguant l'ubiquitine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5384255A (en) * 1993-06-21 1995-01-24 Rappaport Family Institute For Research In The Medical Sciences Ubiquitin carrier enzyme E2-F1, purification, production, and use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995018974A2 (fr) * 1994-01-04 1995-07-13 Mitotix, Inc. Enzymes conjuguant l'ubiquitine

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
NAVA BLUMENFELD ET AL.: "Purification and characterization of a novel species of Ubiquitin-carrier protein, E2, that is involved in degradation of non-"N-end Rule" protein substrates.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 13, 1 April 1994 (1994-04-01), MD US, pages 9574 - 9581, XP002119400 *
PETER KAISER ET AL.: "A human Ubiquitin-conjugating enzyme homologous to yeast UBC8", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 12, 1994, pages 8797 - 8802, XP002283982 *
PIERRE-ALAIN GIROD ET AL.: "Homologs of the essential ubiquitin conjugating enzymes UBC1, 4 and 5 in yeast are encoded by a multigene family in Arabidopsis thaliana", THE PLANT JOURNAL, vol. 3, no. 4, 1993, pages 545 - 552, XP002125332 *
See also references of WO9623410A1 *
SHILIANG QIN ET AL.: "Cloning and characterization of a Saccharomyces cerevisiae gene encoding a new member of the Ubiquitin-conjugating protein family", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 266, no. 23, 1991, pages 15549 - 15554, XP002283981 *
SIMON S. WING ET AL.: "Molecular cloning, expression and characterization of a ubiquitin conjugation enzyme (E217kB) highly expressed in rat testis", BIOCHEMICAL JOURNAL, vol. 305, no. 1, 1 January 1995 (1995-01-01), pages 125 - 132, XP002119403 *
WOLFGANG SEUFERT ET AL.: "UBIQUITIN-CONJUGATING ENZYMES UBC4 AND UBC5 MEDIATE SELECTIVE DEGRADATION OF SHORT-LIVED AND ABNORMAL PROTEINS", THE EMBO JOURNAL, vol. 9, no. 2, 1990, pages 543 - 550, XP002085131 *

Also Published As

Publication number Publication date
EP0814661A1 (fr) 1998-01-07
JPH11501802A (ja) 1999-02-16
WO1996023410A1 (fr) 1996-08-08
AU1869095A (en) 1996-08-21

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