EP0828751A4 - HUMAN NEUROPEPTIDE RECEPTOR - Google Patents

HUMAN NEUROPEPTIDE RECEPTOR

Info

Publication number
EP0828751A4
EP0828751A4 EP95918991A EP95918991A EP0828751A4 EP 0828751 A4 EP0828751 A4 EP 0828751A4 EP 95918991 A EP95918991 A EP 95918991A EP 95918991 A EP95918991 A EP 95918991A EP 0828751 A4 EP0828751 A4 EP 0828751A4
Authority
EP
European Patent Office
Prior art keywords
neuropeptide receptor
human neuropeptide
human
receptor
neuropeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95918991A
Other languages
German (de)
French (fr)
Other versions
EP0828751A1 (en
Inventor
Daniel R Soppet
Yi Li
Craig A Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP0828751A1 publication Critical patent/EP0828751A1/en
Publication of EP0828751A4 publication Critical patent/EP0828751A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP95918991A 1995-05-05 1995-05-05 HUMAN NEUROPEPTIDE RECEPTOR Withdrawn EP0828751A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1995/005616 WO1996034877A1 (en) 1995-05-05 1995-05-05 Human neuropeptide receptor
CA002220036A CA2220036A1 (en) 1995-05-05 1995-05-05 Human neuropeptide receptor

Publications (2)

Publication Number Publication Date
EP0828751A1 EP0828751A1 (en) 1998-03-18
EP0828751A4 true EP0828751A4 (en) 1999-01-20

Family

ID=25679790

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95918991A Withdrawn EP0828751A4 (en) 1995-05-05 1995-05-05 HUMAN NEUROPEPTIDE RECEPTOR

Country Status (3)

Country Link
EP (1) EP0828751A4 (en)
CA (1) CA2220036A1 (en)
WO (1) WO1996034877A1 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410701B1 (en) 1995-05-05 2002-06-25 Human Genome Sciences, Inc. Human neuropeptide receptor
US20030022277A1 (en) * 1995-05-05 2003-01-30 Daniel R. Soppet Human neuropeptide receptor
US6309854B1 (en) * 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US6001963A (en) * 1996-12-17 1999-12-14 Smithkline Beecham Corporation Ligands of the neuropeptide receptor HFGAN72
WO1998047514A1 (en) * 1997-04-24 1998-10-29 Merck Sharp & Dohme Limited Use of an nk-1 receptor antagonist and an ssri for treating obesity
US5935814A (en) * 1997-04-30 1999-08-10 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72Y receptor
US6020157A (en) * 1997-04-30 2000-02-01 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72X receptor
CA2233584A1 (en) * 1997-06-11 1998-12-11 Smithkline Beecham Corporation 7tm receptor hlwar77
US6166193A (en) * 1997-07-25 2000-12-26 Board Of Regents, University Of Texas System Polynucleotides encoding MY1 receptor
JP2003527302A (en) * 1997-12-15 2003-09-16 スミスクライン ビーチャム パブリック リミテッド カンパニー Novel neuropeptide receptor HFGAN72 ligand and therapeutic method using agonist or antagonist thereof
AUPP438598A0 (en) 1998-06-29 1998-07-23 Garvan Institute Of Medical Research NPY-Y7 receptor gene
AU2548400A (en) 1999-02-12 2000-08-29 Smithkline Beecham Plc Novel use of orexin receptor antagonists
US6319710B1 (en) 1999-08-23 2001-11-20 Decode Genetics Ehf. Human narcolepsy gene
US6410712B1 (en) * 1999-10-25 2002-06-25 Decode Genetics Ehf. Human narcolepsy gene
EP1311297B1 (en) * 2000-08-25 2006-07-26 Phase One Pharma Oy Ltd. A method for reducing stress-induced overproduction of neuropeptide y in an individual
CZ20032990A3 (en) 2001-05-05 2004-04-14 Smithkline Beecham P. L. C. N-aroyl cyclic amines
US8129384B2 (en) 2008-10-09 2012-03-06 Glaxo Group Limited Imidazo[1,2-a]pyrazines as orexin receptor antagonists
US8093255B2 (en) 2008-10-09 2012-01-10 Glaxo Group Limited Imidazo[1,2-A]pyrimidines as orexin receptor antagonists
GB0823467D0 (en) 2008-12-23 2009-01-28 Glaxo Group Ltd Novel Compounds
US20120040991A1 (en) 2009-04-24 2012-02-16 Glaxo Group Limited 3-azabicyclo [4.1.0] heptanes used as orexin antagonists
WO2011023585A1 (en) 2009-08-24 2011-03-03 Glaxo Group Limited Piperidine derivatives used as orexin antagonists
US20120149723A1 (en) 2009-08-24 2012-06-14 Romano Di Fabio 5-methyl-piperidine derivatives as orexin receptor antagonists for the treatment of sleep disorder
SI2626350T1 (en) 2010-09-22 2015-09-30 Eisai R&D Management Co., Ltd. Cyclopropane compound
WO2012089606A1 (en) 2010-12-28 2012-07-05 Glaxo Group Limited Azabicyclo [4.1.0] hept - 4 - yl derivatives as human orexin receptor antagonists
WO2012089607A1 (en) 2010-12-28 2012-07-05 Glaxo Group Limited Novel compounds with a 3a-azabicyclo [4.1.0] heptane core acting on orexin receptors
ES2731648T3 (en) 2014-08-06 2019-11-18 Eisai R&D Man Co Ltd Method for producing a pyrimidine-1-ol compound and intermediate compound thereof
SG10202007759RA (en) 2014-10-23 2020-09-29 Eisai R&D Man Co Ltd Compositions and methods for treating insomnia
CN114502167A (en) 2019-09-13 2022-05-13 卫材R&D管理有限公司 Pharmaceutical composition for treating insomnia
KR20220119065A (en) 2019-12-20 2022-08-26 에자이 알앤드디 매니지먼트 가부시키가이샤 Uses of Lemborexant for the Treatment of Insomnia
MA59554B1 (en) 2020-07-17 2026-04-30 Eisai R&D Management Co., Ltd. COMPOUND OF SUBSTITUTED PIPERIDIN AND ITS APPLICATION
AU2023206823A1 (en) 2022-01-14 2024-07-11 Eisai R&D Management Co., Ltd. Crystal of substituted piperidine compound, salts of substituted piperidine compound, and crystals thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005302A1 (en) * 1994-08-11 1996-02-22 Takeda Chemical Industries, Ltd. G protein coupled receptor protein, production, and use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005302A1 (en) * 1994-08-11 1996-02-22 Takeda Chemical Industries, Ltd. G protein coupled receptor protein, production, and use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
H.HERZOG ET AL.: "Genomic Organization, Localization, and Allelic Differences in the Gene for the Human Neuropeptide Y Y1 Receptor", J.BIOL.CHEM., vol. 268, no. 9, 1993, pages 6703 - 7, XP002083378 *
See also references of WO9634877A1 *

Also Published As

Publication number Publication date
WO1996034877A1 (en) 1996-11-07
EP0828751A1 (en) 1998-03-18
CA2220036A1 (en) 1996-11-07

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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