EP0828751A4 - Recepteur de neuropeptides humain - Google Patents

Recepteur de neuropeptides humain

Info

Publication number
EP0828751A4
EP0828751A4 EP95918991A EP95918991A EP0828751A4 EP 0828751 A4 EP0828751 A4 EP 0828751A4 EP 95918991 A EP95918991 A EP 95918991A EP 95918991 A EP95918991 A EP 95918991A EP 0828751 A4 EP0828751 A4 EP 0828751A4
Authority
EP
European Patent Office
Prior art keywords
neuropeptide receptor
human neuropeptide
human
receptor
neuropeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95918991A
Other languages
German (de)
English (en)
Other versions
EP0828751A1 (fr
Inventor
Daniel R Soppet
Yi Li
Craig A Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP0828751A1 publication Critical patent/EP0828751A1/fr
Publication of EP0828751A4 publication Critical patent/EP0828751A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP95918991A 1995-05-05 1995-05-05 Recepteur de neuropeptides humain Withdrawn EP0828751A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1995/005616 WO1996034877A1 (fr) 1995-05-05 1995-05-05 Recepteur de neuropeptides humain
CA002220036A CA2220036A1 (fr) 1995-05-05 1995-05-05 Recepteur de neuropeptides humain

Publications (2)

Publication Number Publication Date
EP0828751A1 EP0828751A1 (fr) 1998-03-18
EP0828751A4 true EP0828751A4 (fr) 1999-01-20

Family

ID=25679790

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95918991A Withdrawn EP0828751A4 (fr) 1995-05-05 1995-05-05 Recepteur de neuropeptides humain

Country Status (3)

Country Link
EP (1) EP0828751A4 (fr)
CA (1) CA2220036A1 (fr)
WO (1) WO1996034877A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030022277A1 (en) * 1995-05-05 2003-01-30 Daniel R. Soppet Human neuropeptide receptor
US6410701B1 (en) 1995-05-05 2002-06-25 Human Genome Sciences, Inc. Human neuropeptide receptor
US6309854B1 (en) * 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US6001963A (en) * 1996-12-17 1999-12-14 Smithkline Beecham Corporation Ligands of the neuropeptide receptor HFGAN72
AU735760B2 (en) * 1997-04-24 2001-07-12 Merck Sharp & Dohme Limited Use of a NK-1 receptor antagonist and an SSRI for treating obesity
US5935814A (en) * 1997-04-30 1999-08-10 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72Y receptor
US6020157A (en) * 1997-04-30 2000-02-01 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72X receptor
CA2233584A1 (fr) * 1997-06-11 1998-12-11 Smithkline Beecham Corporation Hlwar77 codant pour un recepteur 7tm
US6166193A (en) * 1997-07-25 2000-12-26 Board Of Regents, University Of Texas System Polynucleotides encoding MY1 receptor
WO1999030670A2 (fr) * 1997-12-15 1999-06-24 Smithkline Beecham Plc Procedes de traitement utilisant de nouveaux ligands du recepteur hfgan72 de neuropeptides et leurs agonistes ou antagonistes
AUPP438598A0 (en) * 1998-06-29 1998-07-23 Garvan Institute Of Medical Research NPY-Y7 receptor gene
JP2002536425A (ja) * 1999-02-12 2002-10-29 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー オレキシン受容体アンタゴニストの新規用途
US6319710B1 (en) 1999-08-23 2001-11-20 Decode Genetics Ehf. Human narcolepsy gene
US6410712B1 (en) 1999-10-25 2002-06-25 Decode Genetics Ehf. Human narcolepsy gene
ATE333902T1 (de) * 2000-08-25 2006-08-15 Phase One Pharma Oy Ltd Methode zur stessinduzierten neuropeptid-y- überproduktion in einem individuum
BR0209334A (pt) 2001-05-05 2004-06-15 Smithkline Beecham Plc Aminas n-aroil cìclicas
US8129384B2 (en) 2008-10-09 2012-03-06 Glaxo Group Limited Imidazo[1,2-a]pyrazines as orexin receptor antagonists
US8093255B2 (en) 2008-10-09 2012-01-10 Glaxo Group Limited Imidazo[1,2-A]pyrimidines as orexin receptor antagonists
GB0823467D0 (en) 2008-12-23 2009-01-28 Glaxo Group Ltd Novel Compounds
CN102459229A (zh) 2009-04-24 2012-05-16 葛兰素集团有限公司 用作食欲肽拮抗剂的3-氮杂二环[4.1.0]庚烷
US20120149711A1 (en) 2009-08-24 2012-06-14 Glaxo Group Limited Piperidine derivatives used as orexin antagonists
EP2470523A1 (fr) 2009-08-24 2012-07-04 Glaxo Group Limited Dérivés de 5-méthylpipéridine comme antagonistes de récepteurs à orexines pour le traitement d'un trouble du sommeil
RU2571414C2 (ru) 2010-09-22 2015-12-20 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Циклопропановые соединения
WO2012089606A1 (fr) 2010-12-28 2012-07-05 Glaxo Group Limited Dérivés azabicyclo [4.1.0] hept-4-yle en tant qu'antagonistes du récepteur humain de l'orexine
WO2012089607A1 (fr) 2010-12-28 2012-07-05 Glaxo Group Limited Nouveaux composés dotés d'un cœur 3a-azabicyclo[4.1.0]heptane agissant sur les récepteurs d'orexine
ES2731648T3 (es) 2014-08-06 2019-11-18 Eisai R&D Man Co Ltd Método para producir un compuesto de pirimidina-1-ol y compuesto intermedio del mismo
JP6659681B2 (ja) 2014-10-23 2020-03-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 不眠症を治療するための組成物および方法
KR20220061950A (ko) 2019-09-13 2022-05-13 에자이 알앤드디 매니지먼트 가부시키가이샤 불면증을 치료하기 위한 약제학적 조성물
EP4076463A1 (fr) 2019-12-20 2022-10-26 Eisai R&D Management Co., Ltd. Utilisation de lemborexant pour le traitement de l'insomnie
CN119235864A (zh) 2020-07-17 2025-01-03 卫材R&D管理有限公司 取代的哌啶化合物及其用途
WO2023136279A1 (fr) 2022-01-14 2023-07-20 エーザイ・アール・アンド・ディー・マネジメント株式会社 Cristal de composé pipéridine substitué, sels de composé pipéridine substitué et cristaux correspondants

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005302A1 (fr) * 1994-08-11 1996-02-22 Takeda Chemical Industries, Ltd. Proteine receptrice couplee a une proteine g, sa production et son utilisation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005302A1 (fr) * 1994-08-11 1996-02-22 Takeda Chemical Industries, Ltd. Proteine receptrice couplee a une proteine g, sa production et son utilisation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
H.HERZOG ET AL.: "Genomic Organization, Localization, and Allelic Differences in the Gene for the Human Neuropeptide Y Y1 Receptor", J.BIOL.CHEM., vol. 268, no. 9, 1993, pages 6703 - 7, XP002083378 *
See also references of WO9634877A1 *

Also Published As

Publication number Publication date
CA2220036A1 (fr) 1996-11-07
WO1996034877A1 (fr) 1996-11-07
EP0828751A1 (fr) 1998-03-18

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Legal Events

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