EP0828751A4 - Recepteur de neuropeptides humain - Google Patents

Recepteur de neuropeptides humain

Info

Publication number
EP0828751A4
EP0828751A4 EP95918991A EP95918991A EP0828751A4 EP 0828751 A4 EP0828751 A4 EP 0828751A4 EP 95918991 A EP95918991 A EP 95918991A EP 95918991 A EP95918991 A EP 95918991A EP 0828751 A4 EP0828751 A4 EP 0828751A4
Authority
EP
European Patent Office
Prior art keywords
neuropeptide receptor
human neuropeptide
human
receptor
neuropeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95918991A
Other languages
German (de)
English (en)
Other versions
EP0828751A1 (fr
Inventor
Daniel R Soppet
Yi Li
Craig A Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP0828751A1 publication Critical patent/EP0828751A1/fr
Publication of EP0828751A4 publication Critical patent/EP0828751A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP95918991A 1995-05-05 1995-05-05 Recepteur de neuropeptides humain Withdrawn EP0828751A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1995/005616 WO1996034877A1 (fr) 1995-05-05 1995-05-05 Recepteur de neuropeptides humain
CA002220036A CA2220036A1 (fr) 1995-05-05 1995-05-05 Recepteur de neuropeptides humain

Publications (2)

Publication Number Publication Date
EP0828751A1 EP0828751A1 (fr) 1998-03-18
EP0828751A4 true EP0828751A4 (fr) 1999-01-20

Family

ID=25679790

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95918991A Withdrawn EP0828751A4 (fr) 1995-05-05 1995-05-05 Recepteur de neuropeptides humain

Country Status (3)

Country Link
EP (1) EP0828751A4 (fr)
CA (1) CA2220036A1 (fr)
WO (1) WO1996034877A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410701B1 (en) 1995-05-05 2002-06-25 Human Genome Sciences, Inc. Human neuropeptide receptor
US20030022277A1 (en) * 1995-05-05 2003-01-30 Daniel R. Soppet Human neuropeptide receptor
US6309854B1 (en) * 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US6001963A (en) * 1996-12-17 1999-12-14 Smithkline Beecham Corporation Ligands of the neuropeptide receptor HFGAN72
WO1998047514A1 (fr) * 1997-04-24 1998-10-29 Merck Sharp & Dohme Limited Utilisation d'un antagoniste du recepteur nk-1 et d'un inhibiteur selectif de reabsorption de la serotonine (ssri) dans le traitement de l'obesite
US5935814A (en) * 1997-04-30 1999-08-10 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72Y receptor
US6020157A (en) * 1997-04-30 2000-02-01 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72X receptor
CA2233584A1 (fr) * 1997-06-11 1998-12-11 Smithkline Beecham Corporation Hlwar77 codant pour un recepteur 7tm
US6166193A (en) * 1997-07-25 2000-12-26 Board Of Regents, University Of Texas System Polynucleotides encoding MY1 receptor
JP2003527302A (ja) * 1997-12-15 2003-09-16 スミスクライン ビーチャム パブリック リミテッド カンパニー 新規な神経ペプチドレセプターｈｆｇａｎ７２のリガンドおよびそのアゴニストまたはアンタゴニストを用いる治療方法
AUPP438598A0 (en) 1998-06-29 1998-07-23 Garvan Institute Of Medical Research NPY-Y7 receptor gene
AU2548400A (en) 1999-02-12 2000-08-29 Smithkline Beecham Plc Novel use of orexin receptor antagonists
US6319710B1 (en) 1999-08-23 2001-11-20 Decode Genetics Ehf. Human narcolepsy gene
US6410712B1 (en) * 1999-10-25 2002-06-25 Decode Genetics Ehf. Human narcolepsy gene
EP1311297B1 (fr) * 2000-08-25 2006-07-26 Phase One Pharma Oy Ltd. Procede pour reduire la surproduction de neuropeptide y chez une personne
CZ20032990A3 (cs) 2001-05-05 2004-04-14 Smithkline Beecham P. L. C. N-aroylové cyklické aminy
US8129384B2 (en) 2008-10-09 2012-03-06 Glaxo Group Limited Imidazo[1,2-a]pyrazines as orexin receptor antagonists
US8093255B2 (en) 2008-10-09 2012-01-10 Glaxo Group Limited Imidazo[1,2-A]pyrimidines as orexin receptor antagonists
GB0823467D0 (en) 2008-12-23 2009-01-28 Glaxo Group Ltd Novel Compounds
US20120040991A1 (en) 2009-04-24 2012-02-16 Glaxo Group Limited 3-azabicyclo [4.1.0] heptanes used as orexin antagonists
WO2011023585A1 (fr) 2009-08-24 2011-03-03 Glaxo Group Limited Dérivés de pipéridine utilisés comme antagonistes d'orexines
US20120149723A1 (en) 2009-08-24 2012-06-14 Romano Di Fabio 5-methyl-piperidine derivatives as orexin receptor antagonists for the treatment of sleep disorder
SI2626350T1 (sl) 2010-09-22 2015-09-30 Eisai R&D Management Co., Ltd. Spojina ciklopropana
WO2012089606A1 (fr) 2010-12-28 2012-07-05 Glaxo Group Limited Dérivés azabicyclo [4.1.0] hept-4-yle en tant qu'antagonistes du récepteur humain de l'orexine
WO2012089607A1 (fr) 2010-12-28 2012-07-05 Glaxo Group Limited Nouveaux composés dotés d'un cœur 3a-azabicyclo[4.1.0]heptane agissant sur les récepteurs d'orexine
ES2731648T3 (es) 2014-08-06 2019-11-18 Eisai R&D Man Co Ltd Método para producir un compuesto de pirimidina-1-ol y compuesto intermedio del mismo
SG10202007759RA (en) 2014-10-23 2020-09-29 Eisai R&D Man Co Ltd Compositions and methods for treating insomnia
CN114502167A (zh) 2019-09-13 2022-05-13 卫材R&D管理有限公司 用于治疗失眠的药物组合物
KR20220119065A (ko) 2019-12-20 2022-08-26 에자이 알앤드디 매니지먼트 가부시키가이샤 불면증 치료를 위한 렘보렉산트의 용도
MA59554B1 (fr) 2020-07-17 2026-04-30 Eisai R&D Management Co., Ltd. Composé de pipéridine substitué et son application
AU2023206823A1 (en) 2022-01-14 2024-07-11 Eisai R&D Management Co., Ltd. Crystal of substituted piperidine compound, salts of substituted piperidine compound, and crystals thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005302A1 (fr) * 1994-08-11 1996-02-22 Takeda Chemical Industries, Ltd. Proteine receptrice couplee a une proteine g, sa production et son utilisation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005302A1 (fr) * 1994-08-11 1996-02-22 Takeda Chemical Industries, Ltd. Proteine receptrice couplee a une proteine g, sa production et son utilisation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
H.HERZOG ET AL.: "Genomic Organization, Localization, and Allelic Differences in the Gene for the Human Neuropeptide Y Y1 Receptor", J.BIOL.CHEM., vol. 268, no. 9, 1993, pages 6703 - 7, XP002083378 *
See also references of WO9634877A1 *

Also Published As

Publication number Publication date
WO1996034877A1 (fr) 1996-11-07
EP0828751A1 (fr) 1998-03-18
CA2220036A1 (fr) 1996-11-07

Similar Documents

Publication Publication Date Title
NO972016D0 (no) Indolyl-Y-reseptorantagonister
FI960953A7 (fi) Endoteliinireseptoriantagonisteja
BR9612327A (pt) Antagonistas receptores de vitronectina
BR9612378A (pt) Antagonistas receptores de vitronectina
NO983737D0 (no) IL-8 reseptor antagonister
BR9612381A (pt) Antagonistas receptores vitronectina
DE69831176D1 (de) Kappa rezeptor opioid peptide
NO951613D0 (no) Ikke-peptidyl tachykinin reseptorantagonister
NO974913D0 (no) Takrenneanordning
DE69629534D1 (de) Gewebe-Aufzeigevorrichtung
DE19681453T1 (de) Digitalisiersteuereinrichtung
BR9712248A (pt) Antagonista receptores de vitronectina
DE59604607D1 (de) Gelenkloses prothesenfussteil
EP0810994A4 (fr) Antagonistes des recepteurs de fibrinogene
PT805813E (pt) Antagonistas de vasopressina triciclicos
EP0866705A4 (fr) Antagonistes du recepteur de fibrinogene
DE69632082D1 (de) Spülungsvorrichtung
DE59610900D1 (de) Adhäsionsrezeptor-Antagonisten
EP0832125A4 (fr) Recepteur hgber32 de proteine g humaine
DE69607046D1 (de) Spüleinrichtung
EP0809648A4 (fr) Recepteur du neuropeptide y
BR9507220A (pt) Antagonistas de receptores de endotelina
EP0689547A4 (fr) Recepteur alpha1c-adrenergique humain clone
ATE341324T1 (de) Endothelin rezeptor antagonisten
DE69616364D1 (de) Endothelinrezeptorantagonisten

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19971205

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched
AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 20030715

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20091201