EP0851765A4 - THERAPEUTIC AND PROPHYLACTIC PROCESSES THAT USE HEAT SHOCK PROTEINS - Google Patents

THERAPEUTIC AND PROPHYLACTIC PROCESSES THAT USE HEAT SHOCK PROTEINS

Info

Publication number: EP0851765A4
Authority: EP; European Patent Office
Prior art keywords: profilactic; therapeutic; methods; thermal shock; shock proteins
Prior art date: 1995-09-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP96930818A

Other languages

German (de)

English (en)

French (fr)

Other versions

EP0851765A1 (en

Inventor

Pramod K Srivastava

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Fordham University

Original Assignee

Fordham University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-13

Filing date

1996-09-11

Publication date

2000-01-19

1995-09-13 Priority claimed from US08/527,547 external-priority patent/US5935576A/en

1996-09-11 Application filed by Fordham University filed Critical Fordham University

1998-07-08 Publication of EP0851765A1 publication Critical patent/EP0851765A1/en

2000-01-19 Publication of EP0851765A4 publication Critical patent/EP0851765A4/en

Status Ceased legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001176—Heat shock proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6043—Heat shock proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Mycology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Microbiology (AREA)
Hematology (AREA)
Virology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

EP96930818A 1995-09-13 1996-09-11 THERAPEUTIC AND PROPHYLACTIC PROCESSES THAT USE HEAT SHOCK PROTEINS Ceased EP0851765A4 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US527547		1995-09-13
US08/527,547 US5935576A (en)	1995-09-13	1995-09-13	Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens
US08/711,918 US6030618A (en)	1995-09-13	1996-09-10	Therapeutic and prophylactic methods using heat shock proteins
US711918		1996-09-10
PCT/US1996/014556 WO1997010000A1 (en)	1995-09-13	1996-09-11	Therapeutic and prophylactic methods using heat shock proteins

Publications (2)

Publication Number	Publication Date
EP0851765A1 EP0851765A1 (en)	1998-07-08
EP0851765A4 true EP0851765A4 (en)	2000-01-19

Family

ID=27062437

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP96930818A Ceased EP0851765A4 (en)	1995-09-13	1996-09-11	THERAPEUTIC AND PROPHYLACTIC PROCESSES THAT USE HEAT SHOCK PROTEINS

Country Status (5)

Country	Link
EP (1)	EP0851765A4 (2)
JP (1)	JPH11513369A (2)
AU (1)	AU727673B2 (2)
CA (1)	CA2231998A1 (2)
WO (1)	WO1997010000A1 (2)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6773707B1 (en)	1995-08-18	2004-08-10	Sloan-Kettering Institute For Cancer Research	Heat shock protein-based vaccines and immunotherapies
US6331299B1 (en)	1995-08-18	2001-12-18	Sloan-Kettering Institute For Cancer Research	Method for treatment of cancer and infectious disease and compositions useful in same
US6761892B1 (en)	1995-08-18	2004-07-13	Sloan-Kettering Institute For Cancer Research	Heat shock protein-based vaccines and immunotherapies
US6719974B1 (en)	1995-08-18	2004-04-13	Sloan-Kettering Institute For Cancer Research	Heat shock protein-based vaccines and immunotherapies
WO1997006821A1 (en)	1995-08-18	1997-02-27	Sloan-Kettering Institute For Cancer Research	Heat shock protein-based vaccines and immunotherapies
US6017540A (en) *	1997-02-07	2000-01-25	Fordham University	Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
EP1336621B1 (en) *	1997-08-05	2006-05-24	Stressgen Biotechnologies Corporation	Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins
AU2005201826B2 (en) *	1997-08-05	2008-01-17	Nventa Biopharmaceuticals Corporation	Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins
KR20060111731A (ko)	1997-08-05	2006-10-27	스트레스젠 바이오테크놀러지스 코포레이션	사람 유두종 바이러스 항원과 스트레스 단백질을 포함하는융합 단백질을 포함하는 조성물에 의해 유도된 사람 유두종바이러스 항원에 대한 면역 반응
US5948646A (en)	1997-12-11	1999-09-07	Fordham University	Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes
JP4768122B2 (ja)	1998-02-20	2011-09-07	ユニバーシティーオブマイアミ	改変型熱ショックタンパク質−抗原性ペプチド複合体
US6797480B1 (en)	1998-10-05	2004-09-28	University Of Connecticut Health Center	Purification of heat shock/stress protein cell surface receptors and their use as immunotherapeutic agents
AUPQ233799A0 (en)	1999-08-19	1999-09-09	Minister For Agriculture, Minister For Land And Water Conservation For And On Behalf Of The State Of New South Wales	Recombinant sub-unit vaccine
GB9919733D0 (en) *	1999-08-19	1999-10-20	Colaco Camilo	Vaccines against intracellular pathogens
WO2001023421A2 (en)	1999-09-30	2001-04-05	Corixa Corporation	Stress protein compositions and methods for prevention and treatment of cancer and infectious disease
US7378096B2 (en)	1999-09-30	2008-05-27	Health Research, Inc.	Stress protein compositions and methods for prevention and treatment of cancer and infectious disease
US7030228B1 (en)	1999-11-15	2006-04-18	Miltenyi Biotec Gmbh	Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
US7449557B2 (en)	2000-06-02	2008-11-11	University Of Connecticut Health Center	Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy
HK1079705A1 (zh)	2001-08-20	2006-04-13	University Of Connecticut Health Center	包含用於治疗癌症及感染性疾病的热休克蛋白或α2-巨球蛋白的组合物制备方法
EP1551957A4 (en)	2001-10-01	2007-01-24	Univ Duke	ISOLATED POLYPEPTIDE OF THE GRP94 LIGANDEN BINDING DOMAIN AND NUCLEIC ACID, CRYSTALLINE FORM THEREOF, CODING THEREOF, AND SCRAPPING METHOD WHERE IT IS USED
WO2003090686A2 (en) *	2002-04-25	2003-11-06	University Of Connecticut Health Center	Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality
US7420037B2 (en)	2003-02-13	2008-09-02	Antigenics Inc.	Heat shock protein-based vaccines and immunotherapies
WO2004074454A2 (en)	2003-02-20	2004-09-02	University Of Connecticut Health Center	Methods and compositions for the treatment of cancer and infectious disease using alpha (2) macroglobulin-antigenic molecule complexes
CA2517396A1 (en)	2003-02-28	2005-03-10	Antigenics Inc.	Use of lectins to promote oligomerization of glycoproteins and antigenic molecules
US7309491B2 (en)	2003-04-11	2007-12-18	Antigenics Inc.	Heat shock protein-based vaccines and immunotherapies
JP2007505147A (ja) *	2003-09-12	2007-03-08	アンティジェニクスインコーポレーテッド	単純ヘルペスウイルス感染の治療および予防用ワクチン
DK2257301T3 (da)	2008-03-03	2014-04-28	Univ Miami	Immunterapi baseret på allogene cancerceller.
KR20110017356A (ko)	2008-03-20	2011-02-21	유니버시티 오브 마이애미	열충격 단백질 ｇｐ96 백신접종 및 이를 사용하는 방법
AU2010232490B2 (en)	2009-04-03	2016-08-11	Agenus Inc.	Methods for preparing and using multichaperone-antigen complexes
GB0910591D0 (en) *	2009-06-19	2009-07-29	Immunobiology Ltd	Method for the purification of protein complexes
GB0916557D0 (en)	2009-09-21	2009-10-28	Health Prot Agency	Commensal neisserial stress protein complexes
BR112017016681A2 (pt)	2015-02-06	2018-04-10	Heat Biologics Inc	vetor de coexpressão de vacina e moléculas coestimulatórias
SG10201912485PA (en)	2015-05-13	2020-02-27	Agenus Inc	Vaccines for treatment and prevention of cancer
US11666649B2 (en)	2016-10-11	2023-06-06	University Of Miami	Vectors and vaccine cells for immunity against Zika virus
CA3058938A1 (en)	2017-04-04	2018-10-11	Heat Biologics, Inc.	Intratumoral vaccination
MA52363A (fr)	2018-04-26	2021-03-03	Agenus Inc	Compositions peptidiques de liaison à une protéine de choc thermique (hsp) et leurs méthodes d'utilisation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993017712A2 (en) *	1992-03-06	1993-09-16	Biocine Spa	Conjugates formed from heat shock proteins and oligo- or polysaccharides
WO1994003208A1 (en) *	1992-07-30	1994-02-17	Yeda Research And Development Company Ltd.	Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989012455A1 (en) *	1988-06-15	1989-12-28	Whitehead Institute For Biomedical Research	Stress proteins and uses therefor

1996
- 1996-09-11 WO PCT/US1996/014556 patent/WO1997010000A1/en not_active Ceased
- 1996-09-11 AU AU69734/96A patent/AU727673B2/en not_active Ceased
- 1996-09-11 CA CA002231998A patent/CA2231998A1/en not_active Abandoned
- 1996-09-11 JP JP9512062A patent/JPH11513369A/ja not_active Ceased
- 1996-09-11 EP EP96930818A patent/EP0851765A4/en not_active Ceased

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993017712A2 (en) *	1992-03-06	1993-09-16	Biocine Spa	Conjugates formed from heat shock proteins and oligo- or polysaccharides
WO1994003208A1 (en) *	1992-07-30	1994-02-17	Yeda Research And Development Company Ltd.	Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
P. K. SRIVASTAVA ET AL.: "Heat shock protein-peptide complexes in cancer immunotherapy", CURRENT OPINION IN IMMUNOLOGY, vol. 6, 1994, pages 728 - 732, XP002037578 *
See also references of WO9710000A1 *

Also Published As

Publication number	Publication date
AU727673B2 (en)	2000-12-21
CA2231998A1 (en)	1997-03-20
WO1997010000A1 (en)	1997-03-20
JPH11513369A (ja)	1999-11-16
AU6973496A (en)	1997-04-01
EP0851765A1 (en)	1998-07-08

Legal Events

Date	Code	Title	Description
1998-05-22	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1998-07-08	17P	Request for examination filed	Effective date: 19980409
1998-07-08	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2000-01-19	A4	Supplementary search report drawn up and despatched	Effective date: 19991208
2000-01-19	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2000-01-26	RA4	Supplementary search report drawn up and despatched (corrected)	Effective date: 19991208
2001-05-09	17Q	First examination report despatched	Effective date: 20010326
2006-11-22	17Q	First examination report despatched	Effective date: 20010326
2008-05-23	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
2008-06-25	18R	Application refused	Effective date: 20080219

Publication	Publication Date	Title
EP0851765A4 (en)	2000-01-19	THERAPEUTIC AND PROPHYLACTIC PROCESSES THAT USE HEAT SHOCK PROTEINS
NO974965L (no)	1997-12-23	Fremgangsmåter og formuleringer for modulering av den humane seksualrespons
DK0811006T3 (da)	2003-08-04	Benzopyranholdige forbindelser og fremgangsmåde til deres anvendelse
ZA967758B (en)	1997-03-20	Therapeutic and prophylactic methods using heat shock proteins
DE69636569D1 (de)	2006-11-09	Verbesserungen an und bezüglich Registrierkassen
EP0954302A4 (en)	2005-03-02	THERAPEUTIC PROCESSES AND COMPOSITIONS WHICH INCLUDE ISOFLAVONES
NO20002846L (no)	2000-08-14	Inhaleringsanordning og fremgangsmÕte ved samme
NO974494L (no)	1997-11-21	Radiomerkede peptider for diagnostikk og terapi
DE69618972D1 (de)	2002-03-14	Persönliche wärmeregelung
DE69620381D1 (de)	2002-05-08	Spielvorrichtung und system dafür
IS4481A (is)	1997-05-12	Díhýdrópyramídín og notkun þeirra
DK0927075T3 (da)	2004-12-06	Varmevekslerapparat og fremgangsmåde til anvendelse
BR9612263A (pt)	1999-07-13	Compostos quinolina e qinazolina úteis em terapia
DK0863790T3 (da)	2001-07-16	Røggas-rensningsanlæg
DE69614654D1 (de)	2001-09-27	Verschlüsselungsgerät und -verfahren
DE69638000D1 (de)	2009-09-24	Ohrenschützer und -wärmer
FR2757059B1 (fr)	1999-01-29	Nouvelle application therapeutique des derives du pyrrole
FI981408A0 (fi)	1995-12-22	Lämpötoimielin
DK0860196T3 (da)	2005-07-25	Fremgangsmåde og indretning til röggasrensning
NO995222D0 (no)	1999-10-26	Forbedringer i og vedrörende gassgeneratorer
DK0763377T3 (da)	2001-12-17	Røggasbehandlingssystem
EP0733057A4 (en)	1998-08-19	Origin of replication complex genes, proteins and methods
DE59606989D1 (de)	2001-07-05	Gasbeheizbares gerät des persönlichen bedarfs
DE69614491D1 (de)	2001-09-20	5HT1Dalpha und 5HT2A Ligande
NO990303L (no)	1999-03-22	Lipidbindende proteiner og deres terapeutiske og diagnostiske anvendelse