EP0851765A4 - THERAPEUTIC AND PROPHYLACTIC PROCESSES THAT USE HEAT SHOCK PROTEINS - Google Patents

THERAPEUTIC AND PROPHYLACTIC PROCESSES THAT USE HEAT SHOCK PROTEINS

Info

Publication number: EP0851765A4
Authority: EP; European Patent Office
Prior art keywords: profilactic; therapeutic; methods; thermal shock; shock proteins
Prior art date: 1995-09-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

EP96930818A

Other languages

German (de)

English (en)

French (fr)

Other versions

EP0851765A1 (en

Inventor

Pramod K Srivastava

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Fordham University

Original Assignee

Fordham University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-13

Filing date

1996-09-11

Publication date

2000-01-19

1995-09-13 Priority claimed from US08/527,547 external-priority patent/US5935576A/en

1996-09-11 Application filed by Fordham University filed Critical Fordham University

1998-07-08 Publication of EP0851765A1 publication Critical patent/EP0851765A1/en

2000-01-19 Publication of EP0851765A4 publication Critical patent/EP0851765A4/en

Status Ceased legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001176—Heat shock proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6043—Heat shock proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Mycology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Microbiology (AREA)
Virology (AREA)
Hematology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

EP96930818A 1995-09-13 1996-09-11 THERAPEUTIC AND PROPHYLACTIC PROCESSES THAT USE HEAT SHOCK PROTEINS Ceased EP0851765A4 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US527547		1974-11-27
US08/527,547 US5935576A (en)	1995-09-13	1995-09-13	Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens
US08/711,918 US6030618A (en)	1995-09-13	1996-09-10	Therapeutic and prophylactic methods using heat shock proteins
US711918		1996-09-10
PCT/US1996/014556 WO1997010000A1 (en)	1995-09-13	1996-09-11	Therapeutic and prophylactic methods using heat shock proteins

Publications (2)

Publication Number	Publication Date
EP0851765A1 EP0851765A1 (en)	1998-07-08
EP0851765A4 true EP0851765A4 (en)	2000-01-19

Family

ID=27062437

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP96930818A Ceased EP0851765A4 (en)	1995-09-13	1996-09-11	THERAPEUTIC AND PROPHYLACTIC PROCESSES THAT USE HEAT SHOCK PROTEINS

Country Status (5)

Country	Link
EP (1)	EP0851765A4 (2)
JP (1)	JPH11513369A (2)
AU (1)	AU727673B2 (2)
CA (1)	CA2231998A1 (2)
WO (1)	WO1997010000A1 (2)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6719974B1 (en)	1995-08-18	2004-04-13	Sloan-Kettering Institute For Cancer Research	Heat shock protein-based vaccines and immunotherapies
US6761892B1 (en)	1995-08-18	2004-07-13	Sloan-Kettering Institute For Cancer Research	Heat shock protein-based vaccines and immunotherapies
US6331299B1 (en)	1995-08-18	2001-12-18	Sloan-Kettering Institute For Cancer Research	Method for treatment of cancer and infectious disease and compositions useful in same
AU724399B2 (en)	1995-08-18	2000-09-21	Sloan-Kettering Institute For Cancer Research	Heat shock protein-based vaccines and immunotherapies
US6773707B1 (en)	1995-08-18	2004-08-10	Sloan-Kettering Institute For Cancer Research	Heat shock protein-based vaccines and immunotherapies
US6017540A (en) *	1997-02-07	2000-01-25	Fordham University	Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
EP1336621B1 (en) *	1997-08-05	2006-05-24	Stressgen Biotechnologies Corporation	Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins
AU2005201826B2 (en) *	1997-08-05	2008-01-17	Nventa Biopharmaceuticals Corporation	Immune responses against HPV antigens elicited by compositions comprising an HPV antigen and a stress protein or an expression vector capable of expression of these proteins
ATE231917T1 (de)	1997-08-05	2003-02-15	Stressgen Biotechnologies Corp	Immunresponse gegen hpv antigene erregt von zusammensetzungen die ein hpv antigen und ein stressprotein enthalten oder einen expressionsvektor fähig zur expression dieser proteine
US5948646A (en)	1997-12-11	1999-09-07	Fordham University	Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes
ES2439014T3 (es)	1998-02-20	2014-01-21	The University Of Miami	Complejo de péptido antigénico-proteína de choque térmico modificada
US6797480B1 (en)	1998-10-05	2004-09-28	University Of Connecticut Health Center	Purification of heat shock/stress protein cell surface receptors and their use as immunotherapeutic agents
AUPQ233799A0 (en)	1999-08-19	1999-09-09	Minister For Agriculture, Minister For Land And Water Conservation For And On Behalf Of The State Of New South Wales	Recombinant sub-unit vaccine
GB9919733D0 (en) *	1999-08-19	1999-10-20	Colaco Camilo	Vaccines against intracellular pathogens
US7378096B2 (en)	1999-09-30	2008-05-27	Health Research, Inc.	Stress protein compositions and methods for prevention and treatment of cancer and infectious disease
WO2001023421A2 (en)	1999-09-30	2001-04-05	Corixa Corporation	Stress protein compositions and methods for prevention and treatment of cancer and infectious disease
US7030228B1 (en)	1999-11-15	2006-04-18	Miltenyi Biotec Gmbh	Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
AU6669401A (en)	2000-06-02	2001-12-11	Univ Connecticut Health Ct	Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy
PL375043A1 (en)	2001-08-20	2005-11-14	University Of Connecticut Health Center	Methods for preparing compositions comprising heat shock proteins or alpha-2-macroglobulin, useful for the treatment of cancer and infectious disease
WO2003029419A2 (en)	2001-10-01	2003-04-10	Duke University	Three dimensional structure of crystalline grp94 binding domain, and its methods of use
AU2003231098A1 (en) *	2002-04-25	2003-11-10	University Of Connecticut Health Center	Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality
US7420037B2 (en)	2003-02-13	2008-09-02	Antigenics Inc.	Heat shock protein-based vaccines and immunotherapies
DE602004030541D1 (de)	2003-02-20	2011-01-27	Univ Connecticut Health Ct	Verfahren zur herstellung von alpha (2) makroglobulin-antigen-molekül-komplexen
ATE553113T1 (de)	2003-02-28	2012-04-15	Agenus Inc	Verwendung von lektinen zur förderung der oligomerisierung von glycoproteinen und antigenen molekülen
US7309491B2 (en)	2003-04-11	2007-12-18	Antigenics Inc.	Heat shock protein-based vaccines and immunotherapies
EP2289547B1 (en)	2003-09-12	2015-12-16	Agenus Inc.	Vaccine for treatment and prevention of herpes simplex virus infection
EP2257301B1 (en)	2008-03-03	2014-01-22	The University of Miami	Allogeneic cancer cell-based immunotherapy
AU2009226077B2 (en)	2008-03-20	2012-04-19	University Of Miami	Heat shock protein gp96 vaccination and methods of using same
AU2010232490B2 (en)	2009-04-03	2016-08-11	Agenus Inc.	Methods for preparing and using multichaperone-antigen complexes
GB0910591D0 (en) *	2009-06-19	2009-07-29	Immunobiology Ltd	Method for the purification of protein complexes
GB0916557D0 (en)	2009-09-21	2009-10-28	Health Prot Agency	Commensal neisserial stress protein complexes
KR20170109582A (ko)	2015-02-06	2017-09-29	히트 바이오로직스, 인코퍼레이티드	벡터 공동 발현 백신 및 공동 자극 분자
EP3294324A1 (en)	2015-05-13	2018-03-21	Agenus Inc.	Vaccines for treatment and prevention of cancer
CA3040123A1 (en)	2016-10-11	2018-04-19	University Of Miami	Vectors and vaccine cells for immunity against zika virus
US11548930B2 (en)	2017-04-04	2023-01-10	Heat Biologics, Inc.	Intratumoral vaccination
KR20210005646A (ko)	2018-04-26	2021-01-14	아게누스 인코포레이티드	열쇼크 단백질-결합 펩티드 조성물 및 그의 이용 방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993017712A2 (en) *	1992-03-06	1993-09-16	Biocine Spa	Conjugates formed from heat shock proteins and oligo- or polysaccharides
WO1994003208A1 (en) *	1992-07-30	1994-02-17	Yeda Research And Development Company Ltd.	Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0419569B1 (en) *	1988-06-15	1995-09-06	Whitehead Institute For Biomedical Research	Stress proteins and uses therefor

1996
- 1996-09-11 EP EP96930818A patent/EP0851765A4/en not_active Ceased
- 1996-09-11 AU AU69734/96A patent/AU727673B2/en not_active Ceased
- 1996-09-11 CA CA002231998A patent/CA2231998A1/en not_active Abandoned
- 1996-09-11 WO PCT/US1996/014556 patent/WO1997010000A1/en not_active Ceased
- 1996-09-11 JP JP9512062A patent/JPH11513369A/ja not_active Ceased

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993017712A2 (en) *	1992-03-06	1993-09-16	Biocine Spa	Conjugates formed from heat shock proteins and oligo- or polysaccharides
WO1994003208A1 (en) *	1992-07-30	1994-02-17	Yeda Research And Development Company Ltd.	Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
P. K. SRIVASTAVA ET AL.: "Heat shock protein-peptide complexes in cancer immunotherapy", CURRENT OPINION IN IMMUNOLOGY, vol. 6, 1994, pages 728 - 732, XP002037578 *
See also references of WO9710000A1 *

Also Published As

Publication number	Publication date
JPH11513369A (ja)	1999-11-16
AU727673B2 (en)	2000-12-21
EP0851765A1 (en)	1998-07-08
CA2231998A1 (en)	1997-03-20
AU6973496A (en)	1997-04-01
WO1997010000A1 (en)	1997-03-20

Legal Events

Date	Code	Title	Description
1998-05-22	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1998-07-08	17P	Request for examination filed	Effective date: 19980409
1998-07-08	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2000-01-19	A4	Supplementary search report drawn up and despatched	Effective date: 19991208
2000-01-19	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2000-01-26	RA4	Supplementary search report drawn up and despatched (corrected)	Effective date: 19991208
2001-05-09	17Q	First examination report despatched	Effective date: 20010326
2006-11-22	17Q	First examination report despatched	Effective date: 20010326
2008-05-23	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED
2008-06-25	18R	Application refused	Effective date: 20080219

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