EP0873790B1 - Pipette - Google Patents

Pipette Download PDF

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Publication number
EP0873790B1
EP0873790B1 EP98102445A EP98102445A EP0873790B1 EP 0873790 B1 EP0873790 B1 EP 0873790B1 EP 98102445 A EP98102445 A EP 98102445A EP 98102445 A EP98102445 A EP 98102445A EP 0873790 B1 EP0873790 B1 EP 0873790B1
Authority
EP
European Patent Office
Prior art keywords
cylinder
line
valve
piston
suction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP98102445A
Other languages
German (de)
English (en)
Other versions
EP0873790A3 (fr
EP0873790A2 (fr
Inventor
Walter Lutz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Walu Labortechnik GmbH
Original Assignee
Walu Labortechnik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Walu Labortechnik GmbH filed Critical Walu Labortechnik GmbH
Publication of EP0873790A2 publication Critical patent/EP0873790A2/fr
Publication of EP0873790A3 publication Critical patent/EP0873790A3/fr
Application granted granted Critical
Publication of EP0873790B1 publication Critical patent/EP0873790B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops

Definitions

  • the invention relates to a pipetting device for aspirating and dispensing a liquid in a pipette with a housing and a holder for a pipette.
  • a disadvantage of the known pipetting devices is that the suction process the liquid in the pipette is difficult to control.
  • EP-A-0 344 792 describes a pipetting device for aspirating and dispensing one Liquid in a pipette according to the preamble of claim 1 is known.
  • This Pipetting device comprises a housing, a receptacle for a pipette, a cylinder, in which a piston is guided in a longitudinally displaceable manner, and a suction line from the pipette holder to the cylinder.
  • An outlet line is also provided runs from a sealed discharge area for pipette reception. The outflow area can by pressing a button with the ambient pressure be connected so that the liquid present in the pipette leak can.
  • the object of the invention is in a pipetting device according to the preamble of Claim 1 to make the filling process of the pipette more controllable.
  • the pipetting device has a cylinder in which a piston is guided in a longitudinally displaceable manner is.
  • a suction line leads from the pipette holder to the cylinder.
  • a suction valve is provided in the suction line.
  • the piston can then several times are operated, whereby larger volumes of liquid are added to the pipette can be. Furthermore, this can result in a higher accuracy when filling the pipette can be reached.
  • a beak valve is preferably used as the suction valve used.
  • the suction valve or beak valve is preferably in the cylinder or provided in a bulge of the cylinder or cylinder housing.
  • the piston is connected to a piston rod protruding from the cylinder, on which an actuating part is provided.
  • the actuator can be used as a handle or finger grip, in particular in the manner of a deduction in one Pistol or a rifle.
  • the opening of the ventilation line is preferably located on the side of the piston on which also the piston rod lies. Due to the vent line leading into the open or the environment, a Pressure equalization during the suction stroke on the side facing away from the mouth of the suction line Side of the piston.
  • a drain line leading to the outside branches off from the suction line can be closed and opened by a first actuating element. While When the pipette is filled, the drain line is closed. When steered open pressure equalization takes place, through which the liquid from the pipette is drained.
  • the suction line can be closed at one point by a second actuating element and controllable, that on the side facing away from the cylinder of the branch the drain line.
  • vent line that branches off from the vent line and leads to the pipette holder.
  • the vent line is through a third actuator lockable and taxable.
  • the exhaust line is through a fourth actuating element can be closed and opened at one point on the side of the branch of the discharge line facing away from the cylinder.
  • the piston can be spring loaded.
  • the piston is preferably spring-loaded in such a way that the suction movement of the piston is opposed to a spring force. It is advantageous to face away from the mouth of the suction line in the cylinder Provide a compression spring on the side of the piston.
  • the compression spring encloses preferably a piston rod connected to the piston. If at one Pipetting device with a spring-loaded piston, a suction valve or beak valve is provided in the suction line, there is the particular advantage that the after a return movement of a spring force required by a suction movement of the piston can be supported.
  • the piston movement or the piston stroke is limited by a stop.
  • the pipetting device can also be used as a metering device.
  • the The pipetting device is then suitable for sucking in defined liquid volumes. It is advantageous to provide a variable stop so that different predefined volumes can be sucked in.
  • the changeable stops can be provided at the end of a piston rod connected to the piston his. The piston rod can be rotated to set the respective stop and / or there can be a fixed stop in different positions to be brought.
  • a pressure valve on the cylinder provided, which is preferably designed as a beak valve. This is particularly so then advantageous if a suction valve is provided in the suction line.
  • the pressure valve allows air to be removed from the cylinder during the Piston executes a pressure stroke between two suction strokes.
  • the first actuator and the second actuator are preferred provided on a valve operating lever. It is advantageous if the Valve actuation lever in the housing of the pipetting device, i.e. fixed to the housing, is rotatably mounted.
  • the valve actuation lever is preferably with an after outside, that is, arm led out of the housing for actuation or manual actuation Mistake.
  • the third actuator and the fourth actuator are preferred provided on a valve operating lever. This is preferably the case around the same valve actuation lever on which the first actuation element is located and the second actuator are provided.
  • the valve actuation lever is preferably rotatably mounted in the housing.
  • the pipetting device shown in FIG. 1 has a housing 1 in which a cylinder 2 is provided.
  • a piston 3 is guided in a longitudinally displaceable manner in the cylinder 2.
  • a suction line 4 leads to the cylinder 2 to a pipette holder 5, in which one Pipette 6 releasably attached, namely inserted.
  • the pipette holder 5 is in one Inserted housing attachment 7, which is screwed onto the housing 1.
  • the cylinder 2 consists of a cylinder part 8 and a head part 9. It is from Cylinder brackets 10, 11 bordered, which are connected to the housing 1.
  • the piston 3, which is longitudinally displaceable in the cylinder 2, is cup-shaped.
  • the end part of the piston 3 is connected to a piston rod 12, on the latter the piston 3 facing away from a U-shaped extension 13 connects with an actuator 14 is connected.
  • the actuating part 14 is a finger actuating part designed and has the shape of a trigger of a pistol. It is in guided a slot 15 of the housing 1 and so at a distance from a handle part 16 of the housing 1 arranged that one-handed operation is possible.
  • the grip part 16 is gripped with the fist, with the fingers in the depressions of the grip part 16.
  • the index finger can then the recessed grip 17 of the actuating part 14 pull in, i.e. move in the direction of arrow 18.
  • One end of a compression spring is supported on the rear of the end part of the piston 3 19 from which surrounds the piston rod 12 and which in the cylindrical shoulder of the cup-shaped piston 3 is used.
  • the other end of the compression spring 19 is at the Supported cylinder holder 11.
  • the piston rod 12 is in a sleeve shape Approach 20 guided in the cylinder holder 11. With the piston rod 12 is one with her aligned extension 21 connected in a shoulder 22 of the housing 1st is guided and at the end of a plurality of graduated paragraphs 23 are provided, the various stops for the piston rod 12 and thus the stroke movement of the Form piston 3.
  • a suction valve 24 designed as a beak valve is provided in the suction line 4. It is located in an extension 25 which is attached to the head part 9 of the cylinder 2 is molded. Furthermore, on cylinder 2 there is also a beak valve Pressure valve 26 is provided, which on another on the head part 9 of the cylinder 2 proposed approach is attached.
  • a vent line 27 leads from the cylinder 2 to the outside.
  • the vent line 27 opens into the cylinder 2 through the cylinder holder 11, namely the side of the piston facing away from the mouth of the suction line 4 into the cylinder 2 Third
  • a valve actuating lever 32 is provided, which is about an axis 33 is rotatably mounted.
  • a first operating element 34 provided, through which the drain line 28 can be closed and can be opened, a second actuating element 35 through which the suction line 4 can be closed and opened, a third actuating element 36, through which the vent line 27 can be closed and opened, and a fourth actuating element 37, through which the discharge line 29 can be closed and opened is.
  • the valve operating lever 32 has a first lever arm 38 and one second lever arm 39, which enclose an angle of approximately 90 ° between them.
  • the first actuating element 34 and the second actuating element 35 are located at the end of the first lever arm 38.
  • the actuating elements 34, 35 close an angle of about 90 °, the first lever arm 38 substantially in Direction of the bisector runs.
  • the third actuating element is in an analogous manner 36 and the fourth actuating element 37 at the end of the second lever arm 39 arranged.
  • the actuating elements 36, 37 close an angle of about 90 ° with each other, the second lever arm essentially in the direction the bisector runs.
  • the suction line 4 can be closed at one point by the second actuating element 35 and controllable, that on the side facing away from the cylinder 2 of the branch the drain line 28 is.
  • the discharge line 29 is through the fourth Actuating element 37 can be closed and opened at a point on the side of the branch of the discharge line 29 facing away from the cylinder 2.
  • the valve actuation lever 32 is in the "suction" position. In this position, the drain line 28 is through the first actuating element 34 closed.
  • the suction line 4 is opened by the second actuating element 35.
  • the vent line 27 is opened by the third actuating element 36.
  • the discharge line 29 is closed by the fourth actuating element 37.
  • the pressure valve 26 closes and the suction valve 24 is opened.
  • the Air is sucked into the cylinder 2 by the pipette 6 through the suction line 4. On the back of the piston 3, the air can flow out through the vent line 27.
  • the liquid 40 is introduced into the pipette 6 to form a liquid column 41 sucked.
  • the suction process can be repeated.
  • the actuator 14 is released is, the compression spring 19 pushes the piston 3 against the direction of arrow 18 in the Starting position back.
  • the suction valve 24 and closes opens the pressure valve 26.
  • the air in the cylinder 2 escapes through the open Pressure valve 26. Air flows onto the through the open ventilation line 27 Back of the piston 3.
  • the liquid column 41 remains unchanged. Subsequently a new suction process can be carried out through which the liquid column 41 continues to rise.
  • the valve actuation lever 32 is in the "dispense” position. He was in this position by moving the lever arm 42 against the Force of the compression spring 43 fixed to the housing.
  • the scale designation "0” denotes the position “suction”
  • the scale designation "a” the position “discharge”
  • the scale designation "b” the position "eject”. Positions a and b are achieved by manual actuation of the lever arm 42, by means of which the valve actuation lever 32 is rotated about the fulcrum or the axis of rotation 33.
  • the drain line 28 is through the first actuating element 34 has been opened.
  • the suction line 4 is through second actuating element 35 is still open.
  • the vent line 27 is still opened by the third actuating element 36.
  • the exhaust line 29 has been opened by the fourth actuating element 37. All actuators control the associated line.
  • air flows into the pipette. Because the drain line 28 leads outside, a pressure equalization is created, through which the liquid flows out of the pipette 6 downwards. Air also flows through the vent line 27 and the ejection line 29 into the pipette. Because the vent line 27 also leads to the outside, i.e. is connected to the ambient pressure, too this removes the liquid from the pipette 6.
  • the valve actuation lever 32 is in the "eject" position.
  • the valve actuation lever 32 is therefore still further against the axis of rotation 33 has been rotated clockwise so that the lever arm 42 the scale designation b has reached.
  • the drain line 28 is through the first actuating element 34 is still open.
  • the suction line 4 is through the second actuator 35 has been closed.
  • the vent line 27 has been closed by the third actuating element 36.
  • the exhaust line 29 has remained open by the fourth actuating element 37.
  • valve actuation lever 32 schematically shows the switching positions of the valve actuation lever 32 and the actuating elements thereon in their interaction with the different lines.
  • the valve actuation lever 32 is located in the "suction” position, in Fig. 5b in the “discharge” position and in Fig. 5c in the Blow out position.
  • Fig. 6 shows a modified embodiment, which is essentially that corresponds to Fig. 1.
  • the pipette holder 5 ' is not below the handle part 16 arranged, but at the lower end of a bend 45 of the housing 1, the connects to the head part 9 of the cylinder 2 and from there to the front and down runs. Accordingly, the common line 31 is around the cylinder 2 led to the pipette holder 5 '.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices For Use In Laboratory Experiments (AREA)

Claims (8)

  1. Pipette pour l'aspiration et l'amenée d'un liquide dans une pipette (6) comportant un boítier (1), un réceptacle (5) pour une pipette (6), un cylindre (2) dans lequel un piston (3) est guidé de manière à pouvoir se déplacer en longitudinale, qui est relié à une tige de piston (12) se projetant hors du cylindre, tige de piston à laquelle une pièce d'actionnement (14) est prévue, comportant par ailleurs une conduite d'aspiration (4) allant du réceptacle de la pipette (5) au cylindre (2), une soupape d'aspiration (24) étant prévue dans la conduite d'aspiration (4), de préférence une valve à bec,
    caractérisée en ce qu'à partir de la conduite d'aspiration (4) une conduite de décharge (28) conduisant à l'air libre dévie, qui peut être fermée et ouverte par un élément d'actionnement (34),
    que la conduite d'aspiration (4) peut être fermée ou ouverte par un deuxième élément d'actionnement (35) à un autre endroit qui se trouve du côté détourné du cylindre (2) de la déviation de la conduite de décharge (28),
    qu'une conduite de purge (27) est prévue qui conduit du cylindre (2) à l'air libre, qui débouche dans le cylindre (2) du côté du piston (3) détourné de l'embouchure de la conduite d'aspiration (4) dans le cylindre (2) et qui peut être fermée et ouverte par un troisième élément d'actionnement (36) et qu'une conduite d'éjection (29) est prévue qui dévie de la conduite de purge (27) et conduit au réceptacle de la pipette (5) et qui peut être fermée et ouverte par un quatrième élément d'actionnement (37) à un endroit qui se trouve du côté opposé au cylindre (2) de la déviation de la conduite d'éjection (29).
  2. Pipette selon la revendication 1, caractérisée en ce que le piston (3) est exposé à la pression d'un ressort (19).
  3. Pipette selon les revendications 1 ou 2, caractérisée en ce que le mouvement du piston est limité par une butée, de préférence par une butée (23) modifiable.
  4. Pipette selon l'une quelconque des revendications précédentes, caractérisée en ce qu'une soupape de refoulement (26), de préférence une valve à bec, est prévue sur le cylindre (2).
  5. Pipette selon l'une quelconque des revendications précédentes, caractérisée en ce que le premier élément d'actionnement (34) et le second élément d'actionnement (35) sont prévus sur un levier d'actionnement de soupape (32).
  6. Pipette selon la revendication 5, caractérisée en ce que le levier d'actionnement de soupape (32) est logé dans le boítier (1) de manière à pouvoir tourner.
  7. Pipette selon l'une quelconque des revendications précédentes, caractérisée en ce que le troisième élément d'actionnement (36) et le quatrième élément d'actionnement (37) sont prévus sur un levier d'actionnement de soupape (32), de préférence sur le levier d'actionnement de soupape (32) comportant le premier élément d'actionnement (34) et le second élément d'actionnement (35).
  8. Pipette selon la revendication 7, caractérisée en ce que le levier d'actionnement de soupape (32) est logé dans le boítier (1) de manière à pouvoir tourner.
EP98102445A 1997-04-24 1998-02-12 Pipette Expired - Lifetime EP0873790B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1997117361 DE19717361C3 (de) 1997-04-24 1997-04-24 Pipettiergerät
DE19717361 1997-04-24

Publications (3)

Publication Number Publication Date
EP0873790A2 EP0873790A2 (fr) 1998-10-28
EP0873790A3 EP0873790A3 (fr) 1999-09-08
EP0873790B1 true EP0873790B1 (fr) 2003-08-13

Family

ID=7827642

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98102445A Expired - Lifetime EP0873790B1 (fr) 1997-04-24 1998-02-12 Pipette

Country Status (2)

Country Link
EP (1) EP0873790B1 (fr)
DE (2) DE19717361C3 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7093507B2 (en) * 2003-05-12 2006-08-22 Bel-Art Products, Inc. Pipette control arrangement

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1025614A (fr) * 1950-09-12 1953-04-17 Pipette volumétrique
DE1719579U (de) * 1955-11-14 1956-03-29 Wolfgang Sternberg Pipettiergeraet.
DE1598531A1 (de) * 1965-05-18 1969-10-02 Heinz Herenz Maschinell betriebenes Pipettiergeraet
DE2058836A1 (de) * 1970-05-15 1971-11-25 Bezirksinstitut Fuer Veterinae Ventilanordnung an Pipettiervorrichtungen mit Saugball
US3954014A (en) * 1974-12-16 1976-05-04 Becton, Dickinson And Company Multiple shot pipetter
US3963061A (en) * 1975-09-16 1976-06-15 Drummond Scientific Company Apparatus for drawing liquids into, and expelling liquids from a pipette
US4257268A (en) * 1979-08-24 1981-03-24 Data Packaging Corporation Pipetter
DE3818704A1 (de) * 1988-06-01 1989-12-07 Hirschmann Glasgeraete Pipettiergeraet
US5073294A (en) * 1990-03-07 1991-12-17 Hercules Incorporated Process of preparing compositions having multiple oriented mesogens
DE4014588A1 (de) * 1990-05-07 1991-11-14 Hirschmann Glasgeraete Pipettiergeraet
DE4214634C1 (de) * 1992-04-24 1993-10-07 Deutsch & Neumann Gmbh Pipettierhilfe

Also Published As

Publication number Publication date
DE19717361A1 (de) 1998-10-29
DE19717361C3 (de) 2002-08-22
DE59809246D1 (de) 2003-09-18
DE19717361C2 (de) 1999-06-24
EP0873790A3 (fr) 1999-09-08
EP0873790A2 (fr) 1998-10-28

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